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Chemical Structure| 2828433-07-2 Chemical Structure| 2828433-07-2

Structure of Golotimod TFA
CAS No.: 2828433-07-2

Chemical Structure| 2828433-07-2

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Golotimod TFA is an immunomodulatory peptide that enhances anti-tuberculosis effects by inhibiting the STAT3 signaling pathway and reduces the duration and severity of oral mucositis, suitable for research on genital herpes virus (HSV-2) and radiation therapy-related diseases.

Synonyms: SCV 07 TFA; Gamma-D-glutamyl-L-tryptophan TFA

4.5 *For Research Use Only !

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Product Details of Golotimod TFA

CAS No. :2828433-07-2
Formula : C18H20F3N3O7
M.W : 447.36
SMILES Code : O=C(O)[C@H](N)CCC(N[C@H](C(O)=O)CC1=CNC2=C1C=CC=C2)=O.O=C(O)C(F)(F)F
Synonyms :
SCV 07 TFA; Gamma-D-glutamyl-L-tryptophan TFA
MDL No. :MFCD32197311

Safety of Golotimod TFA

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Related Pathways of Golotimod TFA

JAK-STAT

Isoform Comparison

Biological Activity

Description
Golotimod TFA (SCV 07 TFA), an immunomodulatory peptide with antimicrobial properties, enhances the effectiveness of antituberculosis treatments, promotes proliferation in thymic and splenic cells, and boosts macrophage function. It also inhibits STAT3 signaling, reducing the duration and severity of oral mucositis in animal models exposed to radiation alone or combined with Cisplatin. Furthermore, Golotimod TFA (SCV 07 TFA) shows promise as a treatment for recurrent genital herpes simplex virus type 2 (HSV-2)[1][2][3].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.24mL

0.45mL

0.22mL

11.18mL

2.24mL

1.12mL

22.35mL

4.47mL

2.24mL

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