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Chemical Structure| 1301761-96-5 Chemical Structure| 1301761-96-5

Structure of GSK-114
CAS No.: 1301761-96-5

Chemical Structure| 1301761-96-5

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GSK-114 is a highly selective, orally active TNNI3K inhibitor (IC50 = 25 nM) with 40-fold selectivity over B-Raf kinase. TNNI3K is specifically expressed in cardiac tissue, making it suitable for research on heart diseases and cardiac regenerative medicine.

Synonyms: GSK-114

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Product Details of GSK-114

CAS No. :1301761-96-5
Formula : C19H23N5O4S
M.W : 417.48
SMILES Code : O=S(C1=CC=C(N(C)C)C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)=C1)(NC)=O
Synonyms :
GSK-114
MDL No. :MFCD33029288
InChI Key :YUSROMRPOFFTMX-UHFFFAOYSA-N
Pubchem ID :52933152

Safety of GSK-114

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.40mL

0.48mL

0.24mL

11.98mL

2.40mL

1.20mL

23.95mL

4.79mL

2.40mL

 

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