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Chemical Structure| 1702428-31-6 Chemical Structure| 1702428-31-6

Structure of GSK-3β inhibitor 2
CAS No.: 1702428-31-6

Chemical Structure| 1702428-31-6

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GSK-3β inhibitor 2 (Compound 3) is a potent, selective and orally active GSK-3β inhibitor with an IC50 of 1.1 nM. GSK-3β inhibitor 2 can cross the blood-brain barrier. GSK-3β inhibitor 2 has the potential for Alzheimer's disease .

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Product Details of GSK-3β inhibitor 2

CAS No. :1702428-31-6
Formula : C14H14N4O3S
M.W : 318.35
SMILES Code : O=C(C1=C(OC)N=C(C2=CC(NC(C3CC3)=O)=NC=C2)S1)N
MDL No. :MFCD32708518
InChI Key :CYADPSMQNARVII-UHFFFAOYSA-N
Pubchem ID :73333976

Safety of GSK-3β inhibitor 2

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of GSK-3β inhibitor 2

PI3K-AKT
Hedgehog

Isoform Comparison

Biological Activity

Description
GSK-3β inhibitor 2, a potent, selective, and orally bioavailable inhibitor of GSK-3β, exhibits an IC50 of 1.1 nM. Capable of crossing the blood-brain barrier, it holds potential for treating Alzheimer's disease[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.14mL

0.63mL

0.31mL

15.71mL

3.14mL

1.57mL

31.41mL

6.28mL

3.14mL

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