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Chemical Structure| 1346704-33-3 Chemical Structure| 1346704-33-3

Structure of GSK343
CAS No.: 1346704-33-3

Chemical Structure| 1346704-33-3

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GSK343 emerges as an exceptionally potent and selective inhibitor of EZH2, boasting an IC50 of 4 nM.

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Product Details of GSK343

CAS No. :1346704-33-3
Formula : C31H39N7O2
M.W : 541.69
SMILES Code : O=C(C1=CC(C2=CC(N3CCN(C)CC3)=NC=C2)=CC4=C1C=NN4C(C)C)NCC5=C(CCC)C=C(C)NC5=O
MDL No. :MFCD25563250
InChI Key :ULNXAWLQFZMIHX-UHFFFAOYSA-N
Pubchem ID :71268957

Safety of GSK343

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Related Pathways of GSK343

epigenetics

Isoform Comparison

Biological Activity

Target
  • Histone Methyltransferase

    EZH1, IC50:240 nM

    EZH2, IC50:4 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.85mL

0.37mL

0.18mL

9.23mL

1.85mL

0.92mL

18.46mL

3.69mL

1.85mL

References

 

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