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Chemical Structure| 760-78-1 Chemical Structure| 760-78-1

Structure of H-DL-Nva-OH
CAS No.: 760-78-1

Chemical Structure| 760-78-1

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H-DL-Nva-OH is the derivative of L-norvaline which is an inhibitor of arginase.

Synonyms: 2-Aminopentanoic acid; α-Aminopentanoic acid; 2-Aminovaleric acid

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Product Details of H-DL-Nva-OH

CAS No. :760-78-1
Formula : C5H11NO2
M.W : 117.15
SMILES Code : CCCC(N)C(O)=O
Synonyms :
2-Aminopentanoic acid; α-Aminopentanoic acid; 2-Aminovaleric acid
MDL No. :MFCD00064420

Safety of H-DL-Nva-OH

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
A549 cells 10 ug/ml DL-Norvaline inhibited autophagy in A549 cells under low-dose radiation and increased the expression levels of ATM, JNK, and AMBRA1. Front Cell Dev Biol. 2021 May 12;9:650819

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Ralstonia eutropha H16 Bacterial culture model Culture medium addition 0.1% (wt/vol) Single addition, observed for 100 minutes Chemical induction of the stringent response caused an increased accumulation of PHB in the presence of ammonium. Appl Environ Microbiol. 2012 Nov;78(22):8033-44

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

8.54mL

1.71mL

0.85mL

42.68mL

8.54mL

4.27mL

85.36mL

17.07mL

8.54mL

Dissolving Methods
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
 

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