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Chemical Structure| 1825302-42-8 Chemical Structure| 1825302-42-8

Structure of H3B-8800
CAS No.: 1825302-42-8

Chemical Structure| 1825302-42-8

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H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant.

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Product Details of H3B-8800

CAS No. :1825302-42-8
Formula : C31H45N3O6
M.W : 555.71
SMILES Code : O=C(N1CCN(C)CC1)O[C@H]([C@](C)(O)CC[C@@H](O)C2)/C=C/[C@H](C)[C@@H](/C(C)=C/C=C/[C@H](C3=NC=CC=C3)C)OC2=O
MDL No. :N/A

Safety of H3B-8800

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.80mL

0.36mL

0.18mL

9.00mL

1.80mL

0.90mL

17.99mL

3.60mL

1.80mL

 

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