Structure of Hematoxylin
CAS No.: 517-28-2
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Hematoxylin has a dyeing property after oxidation and is usually used as a tissue staining reagent in combination with eosin.
Synonyms: Natural Black 1; Haematoxylin; Hydroxybrazilin
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| CAS No. : | 517-28-2 |
| Formula : | C16H14O6 |
| M.W : | 302.28 |
| SMILES Code : | OC1=C(O)C2=C(C=C1)[C@]3([H])[C@](CC4=C3C=C(O)C(O)=C4)(O)CO2 |
| Synonyms : |
Natural Black 1; Haematoxylin; Hydroxybrazilin
|
| MDL No. : | MFCD00078111 |
| GHS Pictogram: |
|
| Signal Word: | Warning |
| Hazard Statements: | H302-H315-H319-H335 |
| Precautionary Statements: | P261-P305+P351+P338 |
| Description |
Hematoxylin (Natural Black 1), a flavonoid compound sourced from Caesalpinia sappan Linn., is predominantly utilized as a nuclear stain in histological analysis. Additionally, it demonstrates efficacy as an inhibitor of Aβ42 fibrillogenesis, exhibiting an IC50 of 1.6 μM.
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| NCT03418454 | - | Recruiting | December 31, 2021 | Israel ... More >> Barzilai medical Center Recruiting Ashkelon, Israel Contact: Irit Alon, MD, Phd 972-52-3609727 irital@bmc.gov.il Less << | |
| NCT00943891 | - | Unknown | December 2014 | Singapore ... More >> National University Hospital Singapore, Singapore, 119074 Less << | |
| NCT02266420 | Triple Negative Breast Cancers... More >> Without Lymph-node Involvement and < or = 30 mm Less << | Not Applicable | Recruiting | October 2022 | France ... More >> Institut de Cancerologie de L'Ouest - Site Paul Papin Recruiting Angers, France, 49933 Contact: Patrick SOULIE, Md. 0241352740 ext +33 Principal Investigator: Patrick SOULIE, Md. Centre Francois Baclesse Recruiting Caen, France, 14076 Contact: Christelle LEVY, Md. 0231455002 ext +33 Principal Investigator: Christelle LEVY, Md. Centre Jean Perrin Recruiting Clermont-Ferrand, France, 63011 Contact: Marie-Ange MOURET-REYNIER, Pr. 04 73 27 81 37 ext +33 marie-ange.mouret-reynier@cjp.fr Principal Investigator: Marie-Ange MOURET-REYNIER CH Emile ROUX Recruiting Le Puy-en-Velay, France, 43000 Contact: Brigitte MONANGE brigittemonange@orange.fr CHU de LIMOGES - HOPITAL DUPUYTREN Recruiting Limoges, France, 87042 Contact: Laurence VENAT-BOUVET, Md. 05 55 05 88 24 ext +33 laurence.venat@chu-limoges.fr Principal Investigator: Laurence VENAT-BOUVET, Md. Centre Leon Berard Withdrawn Lyon, France, 69008 Institut Paoli Calmettes Recruiting Marseille, France, 13273 Contact: Anthony GONCALVES, Md. 0491223537 ext +33 Principal Investigator: Anthony GONCALVES, Md. Institut Regional Du Cancer Montpellier Recruiting Montpellier, France, 34298 Contact: William JACOT, Md. 0467613151 ext +33 Principal Investigator: William JACOT, Md. Hopital TENON Not yet recruiting Paris, France, 75970 Contact: Joseph GLIGOROV 01 56 01 60 24 joseph.gligorov@tnn.aphp.fr Institut de Cancerologie de L'Ouest - Site Rene Gauducheau Recruiting Saint-Herblain, France, 44805 Contact: Mario CAMPONE, Md. 0240679977 ext +33 Principal Investigator: Mario CAMPONE, Md. Institut Claudius Regaud Recruiting Toulouse, France, 31059 Contact: Florence DALENC, Md. 0531155104 ext +33 Principal Investigator: Florence DALENC, Md. Clinique St Jean Du Languedoc Recruiting Toulouse, France, 31077 Contact: Etienne SUC 05 61 54 90 35 esucsjl@club-internet.fr Institut Gustave Roussy Recruiting Villejuif, France, 94805 Contact: Marie-Christine MATHIEU, Md. 0142114528 ext +33 Principal Investigator: Marie-Christine MATHIEU, Md. Less << |
| NCT01064609 | Interstitial Lung Disease | Not Applicable | Completed | - | Spain ... More >> Hospital de la Sanrta Creu i Sant Pau Barcelona, Spain, 08024 Less << |
| NCT03747068 | - | Completed | - | - | |
| NCT01584414 | - | Completed | - | Israel ... More >> Meir Medical Center Kfar - Sava, Israel Less << | |
| NCT03023475 | CABG Graft Integrity | Not Applicable | Not yet recruiting | December 2017 | Germany ... More >> Kerckhoff Klinik Bad Nauheim, Germany, 61231 Less << |
| NCT00551278 | - | Completed | - | United States, Indiana ... More >> Indiana University Hospital Indianapolis, Indiana, United States, 46202 Less << | |
| NCT03508856 | Actinic Keratosis ... More >> Photo-aged Skin Less << | Not Applicable | Completed | - | - |
| NCT00847340 | - | Completed | - | - | |
| NCT01795066 | Solid Pancreatic Masses | Not Applicable | Unknown | January 2015 | Korea, Republic of ... More >> Division of Gastroenterology, Department of Internal Medicine, Yonsei Institute of Gastroenterology, Yonsei University College of Medicine Recruiting Seoul, Korea, Republic of, 120-752 Contact: Moon Jae Chung, MD +82-2-2228-1981 mjchung@yuhs.ac Less << |
| NCT02638181 | Open-angle Glaucoma | Not Applicable | Completed | - | China, Tianjin ... More >> Tianjin Medical University Eye Hospital Tianjin, Tianjin, China, 300384 Less << |
| NCT02834429 | - | Completed | - | United Kingdom ... More >> Department of Gastroenterology Sheffield, South Yorkshire, United Kingdom, S10 2JF Less << | |
| NCT02845180 | Obesity | Not Applicable | Completed | - | United States, Pennsylvania ... More >> University of Pittsburgh Philadelphia, Pennsylvania, United States, 15261 Less << |
| NCT02745379 | Alveolar Bone Loss | Phase 1 | Unknown | December 2016 | Iran, Islamic Republic of ... More >> School of Dentristry at Shahid Beheshti University of Medical Sciences Recruiting Tehran, Iran, Islamic Republic of, 19839 Contact: Arash Khojasteh, DDS, OMFS 00989121060032 arashkhojasteh@yahoo.com Less << |
| NCT01140776 | - | Terminated | July 2012 | United States, Arizona ... More >> Arizona Cancer Center Tucson, Arizona, United States, 85724 United States, Texas University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Less << | |
| NCT02745366 | Alveolar Bone Loss ... More >> Atrophy Less << | Phase 1 | Unknown | December 2016 | Iran, Islamic Republic of ... More >> School of Dentristry at Shahid Beheshti University of Medical Sciences Recruiting Tehran, Iran, Islamic Republic of, 19839 Contact: Arash Khojasteh, DDS, OMFS 00989121060032 arashkhojasteh@yahoo.com Less << |
| NCT02586025 | Breast Cancer | Phase 3 | Active, not recruiting | April 30, 2022 | China ... More >> The Affiliated Hospital of Military Medical Sciences(The 307th Hospital of Chinese PLA) Beijing, China, 100071 Jilin Cancer Hospital Changchun, China, 130012 the First Hospital of Jilin University Changchun, China, 130021 Fujian Medical University Union Hospital Fujian, China, 350001 Sun Yet-sen University Cancer Center Guangzhou, China, 510060 Guangdong General Hospital Guangzhou, China, 510080 Zhejiang Cancer Hospital Hangzhou, China, 310022 Harbin Medical University Cancer Hospital Harbin, China, 150081 Shandong Cancer Hospital Jinan, China, 250117 The 1st Affiliated Hospital of Nanchang Unversity Nanchang, China, 330006 Jiangsu Province Hospital Nanjing, China, 210036 Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, China, 200025 Fudan University Shanghai Cancer Center Shanghai, China, 200032 Henan Cancer Hospital Zhengzhou, China, 450008 Korea, Republic of Kyungpook National University Medical Center Daegu, Korea, Republic of, 41404 Ajou University Medical Center Gyeonggi-do, Korea, Republic of, 16499 Korea University Guro Hospital Seoul, Korea, Republic of, 08308 Taiwan Taipei Medical University -Shuang Ho Hospital New Taipei City, Taiwan, 23561 China Medical University Hospital; Surgery Taichung, Taiwan, 404 Mackay Memorial Hospital; Dept of Surgery Taipei, Taiwan, 104 Taipei Medical University Hospital Taipei, Taiwan, 110 Wanfang Hospital Taipei, Taiwan, 116 Thailand Bhumibol Adulyadej Hospital; Medicine Bangkok, Thailand, 10220 Srinagarind Hospital, Khon Kaen University; Surgery Khon Kaen, Thailand, 40002 Songklanagarind Hospital; Department of Surgery Songkla, Thailand, 90110 Less << |
| NCT03150901 | - | Completed | - | - | |
| NCT01136369 | - | Completed | - | United States, California ... More >> John Wayne Cancer Institute Santa Monica, California, United States, 90404 United States, Georgia WellStar Health Systems Marietta, Georgia, United States, 30062 United States, Missouri Washington University Medical School Saint Louis, Missouri, United States, 63110 United States, New York Beth Israel Medical Center New York, New York, United States, 10003 United States, North Carolina Central Carolina Surgery, PA Greensboro, North Carolina, United States, 27401 Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 United States, Ohio Breast Care Specialist, Inc. Westerville, Ohio, United States, 43081 United States, Pennsylvania Breast Care Specialist, PC Allentown, Pennsylvania, United States, 18104 United States, Tennessee Nashville Breast Center, PC Nashville, Tennessee, United States, 37203 United States, Texas Dallas Surgical Group Dallas, Texas, United States, 75230 University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Less << | |
| NCT03295175 | - | Recruiting | January 31, 2020 | Colombia ... More >> Luis Gabriel Villarraga Recruiting Bogotá, Colombia, 110231 Contact: Nicolas Fernandez, MD 5946161 nicolasfernandezb@gmail.com Principal Investigator: Jaime Perez, MD Principal Investigator: Nicolas Fernandez, MD Principal Investigator: Luis G Villarraga, MD Sub-Investigator: Eugenio Meek, MD Sub-Investigator: Maddy Mejia, MD Less << |
| Bio Calculators | ||||
| Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
|
1 mM 5 mM 10 mM |
3.12mL 0.62mL 0.31mL |
15.61mL 3.12mL 1.56mL |
31.22mL 6.24mL 3.12mL |
|
| Dissolving Methods |
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:
in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
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