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Chemical Structure| 517-28-2 Chemical Structure| 517-28-2

Structure of Hematoxylin
CAS No.: 517-28-2

Chemical Structure| 517-28-2

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Hematoxylin has a dyeing property after oxidation and is usually used as a tissue staining reagent in combination with eosin.

Synonyms: Natural Black 1; Haematoxylin; Hydroxybrazilin

4.5 *For Research Use Only !

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Product Details of Hematoxylin

CAS No. :517-28-2
Formula : C16H14O6
M.W : 302.28
SMILES Code : OC1=C(O)C2=C(C=C1)[C@]3([H])[C@](CC4=C3C=C(O)C(O)=C4)(O)CO2
Synonyms :
Natural Black 1; Haematoxylin; Hydroxybrazilin
MDL No. :MFCD00078111

Safety of Hematoxylin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Description
Hematoxylin (Natural Black 1), a flavonoid compound sourced from Caesalpinia sappan Linn., is predominantly utilized as a nuclear stain in histological analysis. Additionally, it demonstrates efficacy as an inhibitor of Aβ42 fibrillogenesis, exhibiting an IC50 of 1.6 μM.

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02637141 Celiac Disease Phase 2 Completed - Finland ... More >> ODL Oulu, Finland Tampere University Hospital Tampere, Finland CRST Turku, Finland Less <<
NCT02340312 - Recruiting - United States, Missouri ... More >> The Children's Mercy Hospital Recruiting Kansas City, Missouri, United States, 64108 Contact: Trevor J Cole, B.S.    816-983-6025    tjcole@cmh.edu Less <<
NCT01923168 Breast Cancer Phase 2 Completed - -
NCT00515970 Carcinoma, Basal Cell Not Applicable Suspended(Problems with the el... More >>ectronic data collection program) Less << December 2014 Germany ... More >> Department of Dermatology, Eberhard Karls University Tuebingen, Baden-Wuerttemberg, Germany, 72076 Less <<
NCT02685098 Ischemia Peri... More >>pheral Arterial Disease Peripheral Vascular Disease Vascular Disease Arterial Occlusive Disease Arteriosclerosis Atherosclerosis Cardiovascular Disease Pathologic Processes Orthopedic Procedures Amputation Less << Phase 1 Recruiting September 2019 United States, Indiana ... More >> Indiana University Recruiting Indianapolis, Indiana, United States, 46202 Contact: Kristen E Wanczyk, RN, CCRC    317-988-9548    keevans@iu.edu Less <<
NCT03130920 Liver Metastases Not Applicable Completed - Croatia ... More >> University Hospital Dubrava Zagreb, Croatia, 10000 Less <<
NCT01923168 - Completed - -
NCT02275273 - Completed - Belgium ... More >> CHU Brugmann Brussels, Belgium, 1020 Less <<
NCT02493153 - Unknown July 2016 -
NCT02907736 - Withdrawn(replaced by a new st... More >>udy) Less << - France ... More >> Fondation Ophtalmologique Adolphe de Rothschild Paris, France, 75019 Less <<
NCT03399981 - Active, not recruiting December 31, 2023 United States, Massachusetts ... More >> Research Site Cambridge, Massachusetts, United States, 02142 Less <<
NCT00898846 - Completed - -
NCT02704988 Lymph Node Metastasis ... More >> Colorectal Cancer Less << Not Applicable Active, not recruiting November 2018 Brazil ... More >> Hospital Moinhos de Vento Porto Alegre, Rio Grande Do Sul, Brazil, 90035001 Less <<
NCT01405144 Photoaging Ac... More >>tinic Keratosis Less << Phase 3 Unknown March 2012 Brazil ... More >> Edileia Bagatin Recruiting Sao Paulo, SP, Brazil, 04075-000 Contact: Carolina Zerbini, MD    55-15-97280079    carolzerbini@hotmail.com    Principal Investigator: Carolina Zerbini, MD Less <<
NCT02639572 Chronic Periodontitis Phase 2 Completed - India ... More >> SVS Institute of Dental Sciences, Mahabubnagar Hyderabad, Andhra Pradesh, India, 509002 Less <<
NCT03682276 Hepatocellular Carcinoma Phase 1 Phase 2 Not yet recruiting September 1, 2022 United Kingdom ... More >> Imperial College Healthcare NHS Trust Not yet recruiting London, Greater London, United Kingdom, W12 0HS Contact: Rohini Sharma, MD    02033131151    rohini.sharma2@nhs.net    Contact: Frances Abomeli    02033133089    f.abomeli@imperial.ac.uk    Principal Investigator: Rohini Sharma, MD Less <<
NCT02849821 Inflammatory Bowel Disease Not Applicable Unknown December 2016 -
NCT02056886 Breast Cancer ... More >> Surgery Less << Not Applicable Recruiting January 2022 France ... More >> ICO Paul Papin Recruiting Angers, France, 49000 Contact: Pedro RARO, MD       pedro.raro@ico.unicancer.fr    Principal Investigator: Pedro RARO, Md          ICO René Gauducheau Recruiting Nantes - St Herblain, France, 44800 Contact: Virginie BORDES, MD    +33 2 40 67 99 00 ext 9185    Virginie.Bordes@ico.unicancer.fr    Principal Investigator: Virginie BORDES, MD          Institut Curie Recruiting Paris, France, 75248 Contact: Séverine ALRAN, MD       severine.alran@curie.net    Principal Investigator: Séverine ALRAN, MD Less <<
NCT03539965 - Completed - Brazil ... More >> Instituto Nacional do Cancer - CPQ Rio De Janeiro, Brazil, 20231050 Less <<
NCT03005639 Stage IIIB-C Melanoma Phase 2 Withdrawn(Sponsor has decided ... More >>to close study.) Less << - United States, Virginia ... More >> Inova Schar Cancer Institute Fairfax, Virginia, United States, 22031 Less <<
NCT03488667 Gastro Esophageal Junction Can... More >>cer Stomach Cancer Adenocarcinoma Less << Phase 2 Recruiting April 30, 2021 United States, Kansas ... More >> The University of Kansas Cancer Center Recruiting Westwood, Kansas, United States, 66205 Contact: Kerry Hepler, RN    913-945-7552    ctnursenav@kumc.edu Less <<
NCT02273973 Breast Cancer Phase 2 Completed - -
NCT01695018 - Completed - -
NCT02817984 Healthy Volunteers Phase 1 Completed - United States, Maryland ... More >> Johns Hopkins University School of Medicine Baltimore, Maryland, United States, 21287 Less <<
NCT02623101 Carcinoma, Basal Cell Not Applicable Recruiting - Netherlands ... More >> Canisius Wilhelmina Hospital Not yet recruiting Nijmegen, Netherlands Contact: J AC Alkemade, MD. PhD          Radboud University Medical Center Recruiting Nijmegen, Netherlands Contact: M JP Gerritsen, MD. PhD.          Principal Investigator: M JP Gerritsen, MD. PhD          Sub-Investigator: M Peppelman, PhD          Rijnstate Hospital Not yet recruiting Velp, Netherlands Contact: M B Maessen-Visch, MD. PhD Less <<
NCT00898885 - Completed - -
NCT03425721 - Recruiting June 1, 2019 United States, California ... More >> Skin Care and Laser Physicians (SCLP) of Beverly Hills Recruiting West Hollywood, California, United States, 92269 Belgium Aalst Dermatology Clinic Recruiting Aalst, Belgium, 43-9300 Canada, Ontario Nowell Solish Recruiting Toronto, Ontario, Canada, M5R3N8 Netherlands Poli Kiniek Dermatologie Recruiting Rotterdam, Netherlands, 2193 Less <<
NCT02273973 - Completed - -
NCT01182610 Gastroesophageal Adenocarcinom... More >>a Adenocarcinoma of the Distal Esophagus Adenocarcinomas of the Gastroesophageal Junction Adenocarcinoma of the Proximal Stomach Less << Phase 2 Terminated(Safety concern in a... More >> similar trial enrolling the same patient population) Less << - United States, Arkansas ... More >> Clopton Clinic Jonesboro, Arkansas, United States, 72401 Less <<
NCT03767244 Prostatic Neoplasms Phase 3 Not yet recruiting December 28, 2027 -
NCT01182610 - Terminated(Safety concern in a... More >> similar trial enrolling the same patient population) Less << - -
NCT02872831 Pancreatic Cancer ... More >> Lymphadenopathy Cholangiocarcinoma Less << Not Applicable Unknown November 2017 United States, Pennsylvania ... More >> Thomas Jefferson University Hospital Recruiting Philadelphia, Pennsylvania, United States, 19107 Contact: Ali Siddiqui, MD    215-955-8900    aas138@jefferson.edu    Contact: Thomas Kowalski, MD    2159558900    thomas.kowalski@jefferson.edu    Sub-Investigator: David E Loren, MD          Sub-Investigator: Thomas Kowalski, MD          Principal Investigator: Ali A Siddiqui, MD          Sub-Investigator: Juan Palazo, MD Less <<
NCT01734967 Pancreatic Neoplasms ... More >> CHRONIC PANCREATITIS Less << Not Applicable Completed - Denmark ... More >> Copenhagen University Hospital Herlev Herlev, Denmark, 2730 Romania Research Center of Gastroenterology and Hepatology, Craiva, Romania, 200349, Less <<
NCT01932047 - Unknown April 2015 Korea, Republic of ... More >> Samsung Medical Center Seoul, Gyunggido, Korea, Republic of, 135-710 Less <<
NCT02561832 Breast Cancer Phase 1 Completed - United States, New York ... More >> Research Site New York, New York, United States Research Site Stony Brook, New York, United States Spain Research Site Barcelona, Spain Research Site Madrid, Spain Research Site Valencia, Spain Research Site Zaragoza, Spain Less <<
NCT02205619 Dental Diseases Phase 2 Phase 3 Completed - -
NCT02293811 Crohn Disease-Associated Color... More >>ectal Adenocarcinoma Less << Not Applicable Unknown June 2016 France ... More >> CHU de Nice Not yet recruiting Nice, Alpes-Maritimes, France, 06001 Contact: Hébuterne Xavier, PhD    +33492036168    hebuterne.xavier@chu-nice.fr    Contact: Butori mathilde, Ph       mathilde.butori@gmail.com    Principal Investigator: HEBUTERNE Xavier, Phd Less <<
NCT01668914 Breast Cancer Phase 3 Completed - China, Shandong ... More >> Shandong Cancer Hospital Jinan, Shandong, China, 250117 Less <<
NCT02976987 High Grade Cervical Epithelial... More >> Neoplasia (CIN2+) Less << Phase 2 Completed - Belgium ... More >> CHU Brugmann Hospital Brussels, Belgium, 1020 Less <<
NCT02242929 Nodular Basal Cell Carcinoma Phase 3 Active, not recruiting December 2022 Netherlands ... More >> Maastricht University medical Centre Maastricht, Limburg, Netherlands, 6202AZ Less <<
NCT02631278 Uterine Myoma Not Applicable Unknown August 2017 Italy ... More >> Catholic University of Sacred Heart Rome, Recruiting Rome,, Rome, Italy, 00100 Contact: Giovanni Scambia, Professor    +39-06-30156279    giovanni.scambia@rm.unicatt.it    Principal Investigator: Giovanni Scambia, Professor          Sub-Investigator: Rossitto Cristiano, MD          Sub-Investigator: Tropeano Giovanna, MD          Sub-Investigator: Amoroso Sonia, MD          Catholic University of Sacred Heart Recruiting Rome, Italy, 00100 Contact: Catholic University of Sacred Heart Less <<
NCT01391767 - Completed - United States, Oklahoma ... More >> University of Oklahoma College of Dentistry Oklahoma City, Oklahoma, United States, 73126 Less <<
NCT02891291 - Recruiting May 2019 Taiwan ... More >> National Taiwan University Hospital Recruiting Taipei City, Taiwan, 10002 Contact: JENGWEI TJIU, MDPHD    886-23123456 ext 65315    jengweitjiu@gmail.com Less <<
NCT00526591 Prostate Cancer Phase 2 Terminated(Slow accrual) - United States, Ohio ... More >> Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center Cleveland, Ohio, United States, 44195 Less <<
NCT01623258 - Completed - United States, District of Col... More >>umbia Walter Reed Army Medical Center Washington DC, District of Columbia, United States, 20307-5001 Less <<
NCT00003854 Breast Cancer Phase 3 Completed - -
NCT00645541 Breast Cancer Phase 1 Completed - United States, Texas ... More >> UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT01292876 Traumatic Injury ... More >> Muscle Injury Tendon Injury Soft Tissue Injury Extremity Injury Less << Not Applicable Completed - United States, Maryland ... More >> Walter Reed National Military Medical Center (WRNMMC) Bethesda, Maryland, United States, 20889 United States, Pennsylvania University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 Less <<
NCT01292876 - Completed - -
NCT03001791 Fibrous Hyperplasia on Oral Mu... More >>cosa Less << Not Applicable Completed - Switzerland ... More >> Department of oral Surgery and Stomatology, Dental school, University Bern Bern, Switzerland, 3010 Less <<
NCT00042926 Head and Neck Cancer Not Applicable Completed - -
NCT00526591 - Terminated(Slow accrual) - -
NCT03301350 Breast Cancer ... More >> Triple Negative Breast Cancer Less << Phase 2 Suspended(Toxicity) October 2022 United States, Wisconsin ... More >> University of Wisconsin Carbone Cancer Center Madison, Wisconsin, United States, 53792 Medical College of Wisconsin Milwaukee, Wisconsin, United States, 53226 Less <<
NCT03725059 Breast Cancer Phase 3 Not yet recruiting January 24, 2031 -
NCT03259152 Giant Cell Tumor of Bone Phase 3 Recruiting May 1, 2019 China, Hebei ... More >> Zhuang Zhou Recruiting Shijiazhuang, Hebei, China, 050000 Contact: Zhuang Zhou, Ph.D    +86 18833130669    39094572@qq.com    Contact: Guochuan Zhang, M.D.    +86 13932110889 Less <<
NCT01140763 - Unknown March 2012 United States, Pennsylvania ... More >> Breast Care Specialist, PC Recruiting Allentown, Pennsylvania, United States, 18104 Contact: Charlotte Bryk    610-366-7333    cbryk2@yahoo.com    Principal Investigator: Mark A Gittleman, MD Less <<
NCT03348462 Psoriasis Vulgaris Phase 4 Not yet recruiting April 30, 2018 -
NCT02689921 Breast Neoplasms Phase 2 Active, not recruiting December 2018 United States, Georgia ... More >> Southeastern Regional Medical Center Newnan, Georgia, United States, 30265 United States, Illinois Cancer Treatment Centers of America at Midwestern Regional Medical Center Zion, Illinois, United States, 60099 Less <<
NCT02131064 Breast Neoplasms Phase 3 Completed - -
NCT03515798 Inflammatory Breast Cancer Phase 2 Not yet recruiting April 30, 2025 France ... More >> Institut Sainte Catherine Not yet recruiting Avignon, France Contact: Julien GRENIER, Dr          Principal Investigator: Julien GRENIER, Dr          Institut BERGONIE Not yet recruiting Bordeaux, France Contact: Camille CHAKIBA-BRUGERE, Dr          Principal Investigator: Camille CHAKIBA-BRUGERE, Dr          CENTRE Francois Baclesse Not yet recruiting Caen, France Contact: Christelle LEVY, Dr          Principal Investigator: Christelle LEVY          Centre Oscar Lambret Not yet recruiting Lille, France Contact: Nuria Koteki, Dr          Principal Investigator: Nuria Koteki, Dr          Centre Leon Berard Not yet recruiting Lyon, France Contact: Thomas BACHELOT, Dr          Principal Investigator: Thomas BACHELOT, Dr          Centre Antoine Lacassagne Not yet recruiting Nice, France Contact: Jean-Marc FERRERO, Pr          Principal Investigator: Jean-Marc FERRERO, Pr          Institut Curie Not yet recruiting Paris, France Contact: Jean-Yves PIERGA, Pr          Principal Investigator: Jean-Yves PIERGA, Pr          Centre Henri Becquerel Not yet recruiting Rouen, France Contact: Marianne LEHEURTEUR, Dr          Principal Investigator: Marianne LEHEURTEUR, Dr          Institut Curie hopital rene huguenin Not yet recruiting Saint-Cloud, France Contact: Florence Lerebours, Dr          Principal Investigator: Florence Lerebours          Institut De Cancérologie de l'Ouest Not yet recruiting Saint-Herblain, France Contact: Marie ROBERT, Dr          Principal Investigator: Marie ROBERT, Dr          Institut de cancérologie de la loire Not yet recruiting Saint-Priest-en-Jarez, France Contact: Jean-Philippe JACQUIN, Pr          Principal Investigator: Jean-Philippe JACQUIN, Pr          Centre Paul Strauss Not yet recruiting Strasbourg, France Contact: Thierry PETIT, Pr          Principal Investigator: Thierry PETIT, Pr          IUCT-Oncopole Institut Claudius Rigaud Not yet recruiting Toulouse, France Contact: Florence DALENC, Dr          Principal Investigator: Florence DALENC, Dr          Institut Gustave Roussy Not yet recruiting Villejuif, France Contact: Suzette Delaloge, Dr          Principal Investigator: Suzette Delaloge, Dr Less <<
NCT01902589 - Completed - Israel ... More >> Ha'Emek Medical Center Afula, Israel, 18101 Less <<
NCT03726879 Breast Cancer Phase 3 Not yet recruiting February 8, 2023 -
NCT03511625 Rheumatoid Arthritis Phase 3 Not yet recruiting September 2018 -
NCT02131064 - Completed - -
NCT03490435 - Recruiting December 31, 2019 Poland ... More >> The Chair of Medical Biology, Collegium Medicum of Nicolaus Copernicus University Recruiting Bydgoszcz, Kujawsko-Pomorskie, Poland, 85-092 Contact: Paweł Sutkowy, PhD    +48525853822    p.sutkowy@cm.umk.pl Less <<
NCT03765229 Melanoma Phase 2 Not yet recruiting June 2023 -
NCT03329378 Locally Advanced Breast Cancer Phase 2 Not yet recruiting October 16, 2019 United States, New York ... More >> Mount Sinai Beth Israel Not yet recruiting New York, New York, United States, 10011 Contact: Damien Francois    212-604-6021    damien.francois@mssm.edu    Contact: Tiffany Xing    212-604-6021    tiffany.xing@mountsinai.org    Principal Investigator: Paula Klein, MD          Mount Sinai West Not yet recruiting New York, New York, United States, 10019 Contact: Tahkir Mirzoyev, MD    212-523-7289    takhir.mirzoyev@mountsinai.org    Principal Investigator: Anupama Goel, MD          Icahn School of Medicine at Mount Sinai Not yet recruiting New York, New York, United States, 10029 Contact: Neha Kumarley    212-824-7659    neha.kumarley@mssm.edu    Contact: Jalwa Afroz    212-824-7320    jalwa.afroz@mssm.edu    Principal Investigator: Aarti Bhardwaj, MD Less <<
NCT03569683 Gingival Overgrowth Not Applicable Completed - India ... More >> Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre Hyderabad, Telangana, India, 500060 Less <<
NCT03036488 Triple Negative Breast Neoplas... More >>ms Less << Phase 3 Active, not recruiting March 14, 2025 -
NCT02494869 High Risk for Developing Breas... More >>t Cancer Less << Not Applicable Recruiting July 2019 United States, New York ... More >> Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Neil Iyengar, MD    646-888-4714       Contact: Lee Jones, PhD    646-888-8103       Principal Investigator: Neil Iyengar, MD Less <<
NCT01810640 Brain Death L... More >>iver Disease Less << Not Applicable Terminated(Complications encou... More >>ntered with biopsy in first 6 patients) Less << - United States, New Jersey ... More >> New Jersey Organ and Sharing Network New Providence, New Jersey, United States, 07974 University Hospital Newark, New Jersey, United States, 07101 Less <<
NCT03556358 Breast Cancer ... More >> Breast Neoplasms HER2-positive Breast Cancer Stage II Breast Cancer Stage IIIA Breast Cancer Less << Phase 3 Recruiting March 2020 Bulgaria ... More >> Tanvex Investigational Site Recruiting Burgas, Bulgaria, 8000 Tanvex Investigational Site Recruiting Dobrich, Bulgaria, 9300 Tanvex Investigational Site Recruiting Gabrovo, Bulgaria, 5300 Tanvex Investigational Site Recruiting Pleven, Bulgaria, 5800 Tanvex Investigational Site Recruiting Plovdiv, Bulgaria, 4004 Chile Tanvex Investigational Site Recruiting Temuco, Chile, 4810469 Tanvex Investigational Site Recruiting Viña Del Mar, Chile, 2520598 Georgia Tanvex Investigational Site Recruiting Batumi, Georgia, 6000 Tanvex Investigational Site Recruiting Batumi, Georgia, 6010 Tanvex Investigational Site Recruiting Tbilisi, Georgia, 0144 Tanvex Investigational Site Recruiting Tbilisi, Georgia, 0159 Tanvex Investigational Site Recruiting Tbilisi, Georgia, 0177 Tanvex Investigational Site Recruiting Tbilisi, Georgia, 0179 Tanvex Investigational Site Recruiting Tbilisi, Georgia, 0186 Tanvex Investigational Site Recruiting Tbilisi, Georgia, 112 Tanvex Investigational Site Recruiting Tbilisi, Georgia, 131 Tanvex Investigational Site Recruiting Tbilisi, Georgia, 141 Hungary Tanvex Investigational Site Recruiting Budapest, Hungary, 1122 Tanvex Investigational Site Recruiting Debrecen, Hungary, 4032 Tanvex Investigational Site Recruiting Győr, Hungary, 9024 Tanvex Investigational Site Recruiting Miskolc, Hungary, 3526 Tanvex Investigational Site Recruiting Pécs, Hungary, 7264 Less <<
NCT02495532 Colorectal Neoplasms ... More >> Neoplasm Metastasis Less << Not Applicable Unknown March 2018 Brazil ... More >> Hospital Moinhos de Vento Recruiting Porto Alegre, Rio Grande do Sul, Brazil, 90035001 Contact: Tiago L Ghezzi, MD, PhD    + 555197256265    tlghezzi@terra.com.br Less <<
NCT03077776 Triple-Negative Breast Neoplas... More >>m Less << Not Applicable Recruiting July 2025 France ... More >> Centre Jean Perrin Recruiting Clermont-Ferrand, France Contact: Marie-ANger Mouret-Reynier          Centre George François Leclerc Recruiting Dijon, France Contact: Isabelle Desmoulin          Centre Leon Bérard Recruiting Lyon, France Contact: Olivier TREDAN, MD          Principal Investigator: Olivier TREDAN, MD          Institut Paoli Calmettes Recruiting Marseille, France Contact: Anthony GONCALVES, MD          Principal Investigator: Anthony GONCALVES, MD          Institut de Cancerologie de l'Ouest Not yet recruiting Nantes, France Contact: Jean-Sébastien FRENEL, MD          Principal Investigator: Jean-Sébastien FRENEL, MD          Centre Eugène Marquis Recruiting Rennes, France Contact: Thibault DE LA MOTTE ROUGE, MD          Principal Investigator: Thibault DE LA MOTTE ROUGE, MD          Centre Paul Strauss Recruiting Strasbourg, France Contact: Thierry Petit, MD          Principal Investigator: Thierry Petit, MD          Hopitaux universitaire de strasbourg - Hopital civil Recruiting Strasbourg, France Contact: Phillipe Barthelemy          Institut de Cancérologie de Lorraine Recruiting Vandœuvre-lès-Nancy, France Contact: Anne Kieffer          Gustave Roussy Recruiting Villejuif, France Contact: Monica Arnedos, MD       monica.arnedos@gustaveroussy.fr    Principal Investigator: Monica Arnedos, MD Less <<
NCT03433313 Breast Cancer Phase 3 Not yet recruiting September 3, 2021 -
NCT02972801 Cancer Autoim... More >>mune Disorders Less << Not Applicable Recruiting January 2021 United States, Pennsylvania ... More >> Magee-Womens Hospital Recruiting Pittsburgh, Pennsylvania, United States, 15213 Contact: Kyle E Orwig, PhD    412-641-2460    orwigke@upmc.edu Less <<
NCT03564782 Triple Negative Breast Cancer Early Phase 1 Recruiting December 2021 United States, North Carolina ... More >> Duke University Medical Center Recruiting Durham, North Carolina, United States, 27710 Contact: Shelley Hwang, MD, MPH    919-660-1278    shelley.hwang@duke.edu    Contact: Laura Gorski    919-660-1278    laura.gorski@duke.edu Less <<
NCT03747120 HER2-positive Breast Cancer ... More >> Breast Cancer Less << Phase 2 Not yet recruiting July 2023 United States, California ... More >> Cedars Sinai Medical Center Los Angeles, California, United States, 90048 Less <<
NCT02116725 Denuded Epidermis Phase 2 Unknown September 2014 Denmark ... More >> Digestive Disease Center and Copenhagen Wound Healing Center, University of Copenhagen Recruiting Copenhagen, Denmark, DK-2400 Contact: Heidi F Larsen, MD    (+45) 35313531       Principal Investigator: Lars N Jørgensen, MD, DMSc          Sub-Investigator: Magnus S Ågren, DMSc Less <<
NCT03425656 Malignant Neoplasm of Breast Phase 3 Recruiting October 30, 2018 Iran, Islamic Republic of ... More >> Imam Khomeini hospital Recruiting Tehran, Iran, Islamic Republic of Contact: Morteza Azhdarzadeh, Pharm D    00982143473000    azhdarzadeh.m@orchidpharmed.com Less <<
NCT00203502 Breast Cancer Phase 2 Completed - United States, Arkansas ... More >> University of Arkansas for Medical Sciences Little Rock, Arkansas, United States, 72205 Less <<
NCT00203502 - Completed - -
NCT01818063 - Active, not recruiting - -
NCT02850783 Sentinel Lymph Node Phase 2 Phase 3 Completed - Netherlands ... More >> VU University Medical Center Amsterdam, Noord-Holland, Netherlands, 1081 HV Less <<
NCT03376971 Lesion Lung C... More >>ancer Diagnoses Disease Less << Early Phase 1 Recruiting November 1, 2021 United States, Arizona ... More >> The University of Arizona Recruiting Tucson, Arizona, United States, 85724 Contact: Charles Hennemeyer, MD    520-626-1957    cth@radiology.arizona.edu    Contact: Andrew Rouse, PhD    520-626-5894    rouse@u.arizona.edu    Principal Investigator: Charles Hennemeyer, MD          Principal Investigator: Andrew Rouse, PhD          Principal Investigator: Gregory Woodhead, MD Less <<
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NCT01818063 Estrogen Receptor-negative Bre... More >>ast Cancer HER2-negative Breast Cancer Progesterone Receptor-negative Breast Cancer Stage II Breast Cancer Stage IIIA Breast Cancer Stage IIIB Breast Cancer Stage IIIC Breast Cancer Triple-negative Breast Cancer Less << Phase 2 Active, not recruiting April 30, 2019 United States, Maryland ... More >> Walter Reed National Military Medical Center Bethesda, Maryland, United States, 20889 United States, Pennsylvania Thomas Jefferson University Philadelphia, Pennsylvania, United States, 19107 Reading Hospital Reading, Pennsylvania, United States, 19611 Less <<
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NCT00943891 - Unknown December 2014 Singapore ... More >> National University Hospital Singapore, Singapore, 119074 Less <<
NCT02266420 Triple Negative Breast Cancers... More >> Without Lymph-node Involvement and < or = 30 mm Less << Not Applicable Recruiting October 2022 France ... More >> Institut de Cancerologie de L'Ouest - Site Paul Papin Recruiting Angers, France, 49933 Contact: Patrick SOULIE, Md.    0241352740 ext +33       Principal Investigator: Patrick SOULIE, Md.          Centre Francois Baclesse Recruiting Caen, France, 14076 Contact: Christelle LEVY, Md.    0231455002 ext +33       Principal Investigator: Christelle LEVY, Md.          Centre Jean Perrin Recruiting Clermont-Ferrand, France, 63011 Contact: Marie-Ange MOURET-REYNIER, Pr.    04 73 27 81 37 ext +33    marie-ange.mouret-reynier@cjp.fr    Principal Investigator: Marie-Ange MOURET-REYNIER          CH Emile ROUX Recruiting Le Puy-en-Velay, France, 43000 Contact: Brigitte MONANGE       brigittemonange@orange.fr    CHU de LIMOGES - HOPITAL DUPUYTREN Recruiting Limoges, France, 87042 Contact: Laurence VENAT-BOUVET, Md.    05 55 05 88 24 ext +33    laurence.venat@chu-limoges.fr    Principal Investigator: Laurence VENAT-BOUVET, Md.          Centre Leon Berard Withdrawn Lyon, France, 69008 Institut Paoli Calmettes Recruiting Marseille, France, 13273 Contact: Anthony GONCALVES, Md.    0491223537 ext +33       Principal Investigator: Anthony GONCALVES, Md.          Institut Regional Du Cancer Montpellier Recruiting Montpellier, France, 34298 Contact: William JACOT, Md.    0467613151 ext +33       Principal Investigator: William JACOT, Md.          Hopital TENON Not yet recruiting Paris, France, 75970 Contact: Joseph GLIGOROV    01 56 01 60 24    joseph.gligorov@tnn.aphp.fr    Institut de Cancerologie de L'Ouest - Site Rene Gauducheau Recruiting Saint-Herblain, France, 44805 Contact: Mario CAMPONE, Md.    0240679977 ext +33       Principal Investigator: Mario CAMPONE, Md.          Institut Claudius Regaud Recruiting Toulouse, France, 31059 Contact: Florence DALENC, Md.    0531155104 ext +33       Principal Investigator: Florence DALENC, Md.          Clinique St Jean Du Languedoc Recruiting Toulouse, France, 31077 Contact: Etienne SUC    05 61 54 90 35    esucsjl@club-internet.fr    Institut Gustave Roussy Recruiting Villejuif, France, 94805 Contact: Marie-Christine MATHIEU, Md.    0142114528 ext +33       Principal Investigator: Marie-Christine MATHIEU, Md. Less <<
NCT01064609 Interstitial Lung Disease Not Applicable Completed - Spain ... More >> Hospital de la Sanrta Creu i Sant Pau Barcelona, Spain, 08024 Less <<
NCT03747068 - Completed - -
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NCT00551278 - Completed - United States, Indiana ... More >> Indiana University Hospital Indianapolis, Indiana, United States, 46202 Less <<
NCT03508856 Actinic Keratosis ... More >> Photo-aged Skin Less << Not Applicable Completed - -
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Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.12mL

0.62mL

0.31mL

15.61mL

3.12mL

1.56mL

31.22mL

6.24mL

3.12mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

References

 

Historical Records