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Chemical Structure| 41137-87-5 Chemical Structure| 41137-87-5

Structure of Hirsutenone
CAS No.: 41137-87-5

Chemical Structure| 41137-87-5

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Hirsutenone, a natural product isolated and purified from the eaves of Alnus nepalensis, exhibits anti-cancer effect against prostate cancer through a direct physical inhibition of Akt1/2, attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity, and may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone showed potent PL(pro) inhibitory activity with IC50 value of 4.1µM.

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Product Details of Hirsutenone

CAS No. :41137-87-5
Formula : C19H20O5
M.W : 328.36
SMILES Code : O=C(/C=C/CCC1=CC=C(O)C(O)=C1)CCC2=CC=C(O)C(O)=C2
MDL No. :MFCD20274778

Safety of Hirsutenone

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302+H312-H315-H318-H411
Precautionary Statements:P264-P270-P273-P280-P301+P312+P330-P302+P352+P312-P305+P351+P338+P310-P332+P313-P391-P501
Class:9
UN#:3077
Packing Group:

Related Pathways of Hirsutenone

MAPK
PI3K-AKT

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.05mL

0.61mL

0.30mL

15.23mL

3.05mL

1.52mL

30.45mL

6.09mL

3.05mL

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