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Chemical Structure| 548-04-9 Chemical Structure| 548-04-9

Structure of Hypericin
CAS No.: 548-04-9

Chemical Structure| 548-04-9

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Hypericin, a natural product isolated and purified from the herb of Hypericum perforatum L., is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum.

Synonyms: NSC 407313; NSC 622946; SGX301

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Product Details of Hypericin

CAS No. :548-04-9
Formula : C30H16O8
M.W : 504.44
SMILES Code : O=C1C2=C(O)C=C(O)C3=C2C4=C(C5=C6C(O)=CC(C)=C5C7=C4C1=C(O)C=C7C)C8=C3C(O)=CC(O)=C8C6=O
Synonyms :
NSC 407313; NSC 622946; SGX301
MDL No. :MFCD00016683
InChI Key :YDOIFHVUBCIUHF-UHFFFAOYSA-N
Pubchem ID :3663

Safety of Hypericin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H317
Precautionary Statements:P280-P301+P312+P330

Related Pathways of Hypericin

epigenetics
DNA

Isoform Comparison

Biological Activity

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Mice Alcoholic liver injury model Gavage 168.50 mg/g Once daily for 8 weeks Hyperoside prevents alcoholic liver injury through antioxidation, with effects equivalent to silymarin PMC6912415

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01726764 Type 2 Diabetes ... More >> Depression Less << Phase 1 Completed - Denmark ... More >> Department of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark Odense, Denmark, DK-5000 Less <<
NCT02862236 Subclinical Anxious Adults ... More >> Nootropic Potential of Hypericum and Alprazolam Healthy Adults Less << Phase 4 Completed - Israel ... More >> Technion, Israel Institute of Technology Haifa, Israel Less <<
NCT00000792 HIV Infections PHASE1 COMPLETED 1995-01-01 Johns Hopkins Adult AIDS CRS, ... More >>Baltimore, Maryland, 21287, United States|Beth Israel Deaconess - East Campus A0102 CRS, Boston, Massachusetts, 02215, United States|NY Univ. HIV/AIDS CRS, New York, New York, 10016, United States Less <<
NCT01921881 Type 2 Diabetes Phase 1 Completed - Denmark ... More >> Department of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark Odense C, Denmark, DK-5000 Less <<
NCT02840331 Peritoneal Carcinomatosis Phase 3 Recruiting July 2020 Germany ... More >> University Department of General, Visceral and Transplant Surgery Recruiting Tübingen, Baden.Württemberg, Germany, 72076 Contact: Stefan Beckert, Prof. Dr.    +49-(0)7071-29-86619    stefan.beckert@med.uni-tuebingen.de    Contact: Alfred Königsrainer, Prof. Dr.    +49-(0)7071-29-86619    alfred.koenigsrainer@med.uni-tuebingen.de Less <<
NCT02448381 Cutaneous T-Cell Lymphoma Phase 3 Recruiting - -
NCT00000645 HIV Infections PHASE1 COMPLETED 1994-10-01 Beth Israel Deaconess - East C... More >>ampus A0102 CRS, Boston, Massachusetts, 02215, United States|University of Minnesota, ACTU, Minneapolis, Minnesota, United States|NY Univ. HIV/AIDS CRS, New York, New York, 10016, United States Less <<
NCT05380635 Cutaneous T-Cell Lymphoma/Myco... More >>sis Fungoides Less << PHASE2 COMPLETED 2022-08-16 Rochester Skin Lymphoma Medica... More >>l Group, Fairport, New York, 14450, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.98mL

0.40mL

0.20mL

9.91mL

1.98mL

0.99mL

19.82mL

3.96mL

1.98mL

References

 

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