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Type HazMat fee for 500 gram (Estimated)
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Limited Quantity USD 15-60
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Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
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Chemical Structure| 78919-13-8 Chemical Structure| 78919-13-8

Structure of Iloprost
CAS No.: 78919-13-8

Chemical Structure| 78919-13-8

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Iloprost is a synthetic analogue of prostacyclin PGI2.

Synonyms: Ciloprost; ZK 36374; Iloprost, Endoprost, Ilomedin, Ciloprost, Ventavis, CHEMBL494

4.5 *For Research Use Only !

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Product Details of Iloprost

CAS No. :78919-13-8
Formula : C22H32O4
M.W : 360.49
SMILES Code : O=C(O)CCC/C=C1C[C@@]2([H])C[C@@H](O)[C@H](/C=C/[C@@H](O)C(C)CC#CC)[C@@]2([H])C\1
Synonyms :
Ciloprost; ZK 36374; Iloprost, Endoprost, Ilomedin, Ciloprost, Ventavis, CHEMBL494
MDL No. :MFCD00867145

Safety of Iloprost

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H311-H331-H361
Precautionary Statements:P260-P262-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310-P403+P233
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Iloprost

GPCR

Isoform Comparison

Biological Activity

Description
Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analog that plays a role in embryo development, reduces inflammation, and prevents tumor metastasis. It is applicable in studies related to peripheral vascular conditions[1].[2].[3].[4].

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00887978 Pulmonary Hypertension Phase 3 Completed - -
NCT03610217 Scleroderma, Systemic ... More >> Sclerosis, Systemic Less << Not Applicable Not yet recruiting October 2021 Canada, Ontario ... More >> Saint Joseph's Health Care London Not yet recruiting London, Ontario, Canada, n6a 4v2 Contact: Janet E Pope, MD, MPH, FRCPSC    15196466332    Janet.Pope@sjhc.london.on.ca    Contact: Andreu Fernandez-Codina    151964661023    doccodina@gmail.com Less <<
NCT00380068 Pulmonary Hypertension Phase 3 Completed - -
NCT01347216 - Recruiting June 2020 Belgium ... More >> Dept. of Pneumology, University Recruiting Leuven, Belgium Contact: Marion Delcroix, MD, PhD          Principal Investigator: Marion Delcroix, MD, PhD          Germany DRK-Klinikum Köpenick Recruiting Berlin, Germany Contact: Christian Opitz, MD, PhD          Principal Investigator: Christian Opitz, MD, PhD          Lung Centre, University of Giessen Recruiting Giessen, Germany Contact: Ardeschir Ghofrani, MD, PhD          Principal Investigator: Ardeschir Ghofrani, MD          Sub-Investigator: Melanie Thamm, MD          Department of Pulmology; Hannover Medical School Recruiting Hannover, Germany Contact: Marius M Hoeper          Principal Investigator: Marius M Hoeper, MD, PhD          Sub-Investigator: Karen Olsson, MD          German Heart Centre Recruiting Munich, Germany Contact: Harald Kaemmerer, MD,. PhD          Principal Investigator: Harald Kaemmerer, MD, PhD          Ireland Mater Misericordiae Recruiting Dublin, Ireland Contact: Sean Gaine, MD, PhD          Principal Investigator: Sean Gaine, MD, PhD          Italy Department of Cardiovascular and Respiratory Sciences, University La Sapienza Recruiting Rome, Italy Contact: Dario Vizza, MD, PhD          Principal Investigator: Dario Vizza, MD, PhD          Switzerland Dept. for Rheumatology, University Hospital Recruiting Zurich, Switzerland Contact: Oliver Distler, MD, PhD          Principal Investigator: Oliver Distler, MD, PhD Less <<
NCT02565030 - Active, not recruiting October 2021 United Kingdom ... More >> Sheffield Teaching Hospitals NHS Foundation Trust Sheffield, South Yorkshire, United Kingdom, S10 2JF Less <<
NCT02551042 Systemic Sclerosis Phase 2 Unknown September 2018 United Kingdom ... More >> Royal Free London NHS Foundation Trust Recruiting London, United Kingdom, NW3 2QG Less <<
NCT03754660 Hypertension, Pulmonary Phase 1 Not yet recruiting March 6, 2020 Germany ... More >> Universitätsklinikum Giessen und Marburg Not yet recruiting Gießen, Hessen, Germany, 35392 Less <<
NCT01467791 - Unknown January 2018 United States, Ohio ... More >> University of Cincinnati Recruiting Cincinnati, Ohio, United States, 45267 Contact: Rebecca Ingledue    513-584-6252    ingledra@ucmail.uc.edu    Principal Investigator: Robert P Baughman, MD          Sub-Investigator: Peter Engel, MD Less <<
NCT01266265 - Completed - -
NCT00380068 - Completed - -
NCT01266265 - Completed - -
NCT00452218 Pulmonary Arterial Hypertensio... More >>n Less << Phase 1 Completed - United States, Illinois ... More >> The University of Chicago Chicago, Illinois, United States, 60637 Less <<
NCT00314548 Adult Respiratory Distress Syn... More >>drome Pulmonary Hypertension Less << Not Applicable Completed - -
NCT01836263 - Unknown June 2017 France ... More >> Université Paris Descartes, Hôpital Cochin, Service de Rhumatologie A & INSERM 1016 Recruiting Paris, France, 75014 Principal Investigator: Yannick Allanore, Prof.          Germany Justus-Liebig-University Gießen, Kerckhoff Clinic, Departement of Rheumatology and Clinical Immunology Recruiting Bad Nauheim, Germany, 61231 Principal Investigator: Ulf Müller-Ladner, Prof.          Sub-Investigator: Ingo H. T, Dr.          Sub-Investigator: Marc Frerix, Dr.          Charité Universitätsmedizin Berlin, Charité Centrum 12 für Innere Medizin und Dermatologie, Medizinische Klinik mit Schwerpunkt Rheumatologie und Klinische Immunologie Recruiting Berlin, Germany, 10117 Principal Investigator: Gabriela Riemekasten, Prof.          Centre for Pediatric Rheumatology, Klinikum Eilbek Recruiting Hamburg, Germany, 22081 Principal Investigator: Ivan Foeldvari, Dr.          Hungary Pecsi Tudomanyegyetem - University of Pecs Recruiting Pecs, Hungary, H-7622 Principal Investigator: Laszlo Czirjak, Prof.          Italy University of Florence, Denothe Centre, Division of Rheumatology AOUC, Department of Biomedicine Recruiting Firenze, Italy, 50139 Principal Investigator: Marco Matucci-Cerinic, Prof.          Policlinico, Via Pansini Recruiting Napoli-Italia, Italy, 5-80131 Principal Investigator: Gabriele Valentini, Prof.          Switzerland Felix-Platter Spital, University of Basel Recruiting Basel, Switzerland, CH 4012 Principal Investigator: Ulrich Walker, Prof.          University of Zurich, Department of Rheumatology Recruiting Zurich, Switzerland, 8006 Principal Investigator: Oliver Distler, Prof.          United Kingdom The Universitiy of Leeds, Division of Rheumatic and Musculoskeletal Disease, St James's University Hospital Recruiting Leeds, United Kingdom, LS9 7TF Principal Investigator: Francesco Del Galdo, Dr.          Royal Free Hospital, University College London Recruiting London, United Kingdom, NW3 2QG Principal Investigator: Christopher Denton, Prof. Less <<
NCT00887978 - Completed - -
NCT00705588 Pulmonary Arterial Hypertensio... More >>n Less << Phase 4 Unknown - Israel ... More >> Pulmonary Institute, Rabin Medical Center Not yet recruiting Petach Tikva, Israel, 49100 Sub-Investigator: Benjamin D Fox, BM BCh MRCP Less <<
NCT03406988 Systemic Sclerosis ... More >> Digital Ulcer Less << Not Applicable Recruiting March 31, 2018 Italy ... More >> UOC Day Hospital Reumatologia, ASST G. Pini-CTO Recruiting Milan, Italy, 20122 Contact: Nicoletta Del Papa, MD    +39-0258296415    nicoletta.delpapa@asst-pini-cto.it Less <<
NCT01179776 Myocardial Infarct Phase 1 Phase 2 Completed - Denmark ... More >> Lene Holmvang Copenhagen, Denmark, 2100 Less <<
NCT01757808 Pulmonary Arterial Hypertensio... More >>n Less << Phase 1 Completed - United States, Illinois ... More >> University of Chicago Chicago, Illinois, United States, 60637 Less <<
NCT01532544 Pneumonia Phase 2 Terminated(Difficulty recruiti... More >>ng patients, company closed down) Less << - Denmark ... More >> University hospital Copenhagen Copenhagen, Denmark, 2100 Vejle hospital Vejle, Denmark Finland Kuopio University Hospital Kuopio, Finland Tampere University Hospital Tampere, Finland, 33521 Less <<
NCT01649739 Pulmonary Arterial Hypertensio... More >>n Less << Phase 4 Unknown January 2014 Israel ... More >> Pulmonary Institute,Rabin Medical Center Not yet recruiting Petach Tikva, Israel, 49100 Contact: Mordechai R Kramer, MD    972-39377221    kremerm@clalit.org.il    Principal Investigator: Mordechai R Kramer, MD Less <<
NCT00428883 Scleroderma, Diffuse Phase 2 Phase 3 Unknown - Italy ... More >> Università politecnica delle marche Recruiting Ancona, Italy, 60020 Contact: Armando Gabrielli, MD,professor    +390712206104    a.gabrielli@univpm.it    Contact: Giovanni Pomponio, MD    +390715964205    g.pomponio@ao-umbertoprimo.marche.it    Principal Investigator: Armando Gabrielli, MD,professor          Università de L’Aquila Recruiting Aquila, Italy Contact: Roberto Giacomelli, Ph       roberto.giacomelli@cc.univaq.it    Principal Investigator: Roberto Giacomelli, MD,professor          Università di Firenze Recruiting Firenze, Italy Contact: Marco Matucci-Cerinic, MD,professor       cerinic@unifi.it    Principal Investigator: Marco Matucci-Cerinic, MD,professor          Seconda Università di Napoli Recruiting Napoli, Italy Contact: Gabriele Valentini, MD,professor       gabriele.valentini@unina2.it    Principal Investigator: Gabriele Valentini, MD,professor          Catholic University of the Sacred Recruiting Roma, Italy Contact: Gianfranco Ferraccioli, MD,professor          Principal Investigator: Gianfranco Ferraccioli, MD,professor Less <<
NCT01389206 - Completed - -
NCT00458042 Hypertension, Pulmonary Phase 4 Terminated(Low Enrollment) - United States, California ... More >> UCSD Medical Center Thornton Hospital La Jolla, California, United States, 92037 UCSD Medical Center Hillcrest Campus San Diego, California, United States, 92103 Less <<
NCT00004786 Systemic Sclerosis ... More >> Raynaud Disease Less << Phase 3 Completed - -
NCT01468545 - Completed - Spain ... More >> Many Locations, Spain Less <<
NCT00741819 Pulmonary Arterial Hypertensio... More >>n Less << Phase 4 Completed - United States, Alabama ... More >> University of Alabama Birmingham Birmingham, Alabama, United States, 35294 United States, California UCSD Medical Center La Jolla, California, United States, 82037 Ronald Reagan UCLA Medical Center Los Angeles, California, United States, 90095 United States, Kansas Kansas University Medical Center Kansas City, Kansas, United States, 66160 United States, New York Long Island Jewish Medical Center - North Shore New Hyde Park, New York, United States, 11040 Beth Israel Medical Center New York City, New York, United States, 10003-3314 Cornell University Medical Center New York City, New York, United States, 10021 Columbia Presbyterian Medical Center New York, New York, United States, 10032 Mary M. Parkes Center for Asthma, Allergy and Pulmonary Care Rochester, New York, United States, 14623 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Ohio Ohio State University Medical Center Columbus, Ohio, United States, 43210 United States, Pennsylvania Allegheny General Hospital Pittsburgh, Pennsylvania, United States, 15212 University of Pittsburg Medical Center Pittsburgh, Pennsylvania, United States, 15213 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 United States, Texas Baylor College of Medicine Houston, Texas, United States, 77030 Less <<
NCT01774058 Diabetes Arte... More >>riosclerosis Peripheral Arterial Occlusive Disease Neuropathy Less << Phase 2 Recruiting June 2019 Austria ... More >> Department of vascular and endovascular surgery, Georg Hagmüller Institute for Vascular Research Wilhelminenhospital Recruiting Vienna, Austria, 1160 Contact: Afshin Assadian, Prim PD Dr    +34(0)1491504101    afshin.assadian@wienkav.at    Contact: Kornelia Hirsch, Dr    +34(0)1491504101    kornelia.hirsch@wienkav.at    Principal Investigator: Afshin Assadian, Prim. PD.Dr Less <<
NCT02032836 Pulmonary Arterial Hypertensio... More >>n Less << Phase 1 Phase 2 Completed - Austria ... More >> Graz, Steiermark, Austria, 8036 Germany München, Bayern, Germany, 80639 Würzburg, Bayern, Germany, 97067 Gießen, Hessen, Germany, 35392 Köln, Nordrhein-Westfalen, Germany, 50924 Hamburg, Germany, 20246 Less <<
NCT01062282 - Completed - Korea, Republic of ... More >> Many Locations, Korea, Republic of Less <<
NCT02238535 Residual Pulmonary Hypertensio... More >>n Less << Phase 2 Unknown October 2016 Russian Federation ... More >> State Research Institute of Circulation Pathology Recruiting Novosibirsk, Russian Federation, 630055 Contact: Yulia Klevanets, MD    +79139443607    klevanetc@yandex.ru Less <<
NCT00882947 - Completed - China ... More >> Many Locations, China Less <<
NCT00741819 - Completed - -
NCT00250640 - Completed - -
NCT01283958 - Completed - -
NCT00086463 Pulmonary Arterial Hypertensio... More >>n Ayerza Syndrome Pulmonary Hypertension Less << Phase 2 Completed - United States, Alabama ... More >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, California UCSD Medical Center La Jolla, California, United States, 92037 Stanford University Medical Center Palo Alto, California, United States, 94305 UCSF Medical Center San Francisco, California, United States, 94143 Harbor-UCLA Medical Center Torrance, California, United States, 90502 United States, Colorado The Children's Hospital Denver, Colorado, United States, 80218 University of Colorado HSC Denver, Colorado, United States, 80262 United States, Illinois Rush Heart Institute, Center for Pulmonary Heart Disease Chicago, Illinois, United States, 60612 United States, Maryland Johns Hopkins University Baltimore, Maryland, United States, 21205 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48109 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55095 United States, New York Columbia University Medical Center New York, New York, United States, 10032 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Pennsylvania University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 United States, Texas Baylor College of Medicine Houston, Texas, United States, 77030 United States, Utah Latter Day Saints Hospital Salt Lake City, Utah, United States, 84143 Less <<
NCT01718288 Peripheral Arterial Disease Phase 4 Completed - Italy ... More >> Angiology, Hospital "G. Fucito" Mercato San Severino, Salerno, Italy, 84085 Internal Medicine, Hospital "Policlinico" Bari, Italy, 70124 Angiology, Hospital "Ferrarotto - Alessi" Catania, Italy, 95100 Internal Medicine, Hospital "Pugliese - Ciaccio" Catanzaro, Italy, 88100 Internal Medicine, Hospital of Fermo Fermo, Italy, 63900 Vascular Surgery, Hospital "Galliera" Genoa, Italy, 16128 Internal Medicine, Hospital Civile Legnano, Italy, 20025 Internal Medicine, "Madonna delle Grazie" Hospital Matera, Italy, 75100 Internal Medicine, Hospital "Fatebenefratelli" Naples, Italy, 80123 Surgery Dept., Hospital " San Giovanni Bosco" Naples, Italy, 80144 Internal Medicine, Hospital "Bianchi Melacrino Morelli" Reggio Calabria, Italy, 89100 Internal Medicine, Hospital Policlinico Campus Biomedico Rome, Italy, 00155 Internal Medicine, Hospital "Fondazione Circolo Macchi" Varese, Italy, 21100 Internal Medicine, Hospital "Jazzolino" Vibo Valentia, Italy, 89900 Less <<
NCT00120380 Hypertension Phase 4 Terminated(Futility analysis) - Germany ... More >> Hannover Medical School Hannover, Germany, 30625 Less <<
NCT02685618 Cardiac Arrest Phase 2 Completed - Denmark ... More >> Dept. of Cardiology, 2143, Rigshospitalet Copenhagen, Denmark, DK-2100 Less <<
NCT00216931 Persistent Pulmonary Hypertens... More >>ion Respiratory Distress Syndrome Less << Not Applicable Withdrawn(No patients enrolled... More >> after three years) Less << October 2008 Sweden ... More >> University Hospital in Lund , Department of Pediatrics Lund, Sweden, 221 85 Less <<
NCT00109681 Pulmonary Fibrosis ... More >> Pulmonary Hypertension Less << Phase 2 Completed - United States, Alabama ... More >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, California UCLA School of Medicine Los Angeles, California, United States, 90095 University of California, San Diego San Diego, California, United States, 92037 University of California, San Francisco San Francisco, California, United States, 94143 United States, Florida University of Miami Miami, Florida, United States, 33136 United States, Illinois The University of Chicago Chicago, Illinois, United States, 60637 United States, Iowa University of Iowa College of Medicine Iowa City, Iowa, United States, 52242 United States, Louisiana Tulane University New Orleans, Louisiana, United States, 70112 United States, Michigan University of Michigan Health System Ann Arbor, Michigan, United States, 48109 United States, Minnesota Mayo Clinic Rochester Rochester, Minnesota, United States, 55905 United States, New York Mount Sinai Medical Center New York, New York, United States, 10029 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Pennsylvania University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania, United States, 15213 United States, Tennessee Vanderbilt University Medical Nashville, Tennessee, United States, 37232 United States, Texas Baylor College of Medicine Houston, Texas, United States, 77030 University of Texas Health Center at Tyler Tyler, Texas, United States, 75708 United States, Virginia Inova Research Center Church Falls, Virginia, United States, 22042 Less <<
NCT01389271 - Completed - Turkey ... More >> Multiple Locations, Turkey Less <<
NCT00414687 Hypertension, Pulmonary Phase 2 Completed - -
NCT01054105 Pulmonary Arterial Hypertensio... More >>n Less << COMPLETED 2018-12-25 Soonchunhyang University Buche... More >>on Hospital, Bucheon, Korea, Republic of|Gachon University Gil Hospital, Incheon, 405-760, Korea, Republic of|Seoul National University Bundang Hospital, Seongnam, Korea, Republic of|Catholic University Seoul Saint Mary's Hospital, Seoul, Korea, Republic of|Seoul National University Hospital, Seoul, Korea, Republic of|Sungkyunkwan University Seoul Samsung Hospital, Seoul, Korea, Republic of Less <<
NCT01082484 Healthy Phase 1 Phase 2 Completed - France ... More >> Unité de Pharmacologie Clinique, Inserm CIC3, CHU Grenoble Grenoble, France, 38043 Less <<
NCT01971450 - Completed - Russian Federation ... More >> Multiple Locations, Russian Federation Less <<
NCT02490657 Video-assisted Thoracoscopic S... More >>urgery Chronic Obstructive Pulmonary Disease Less << Not Applicable Completed - Korea, Republic of ... More >> Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine Seoul, Korea, Republic of, 120-752 Less <<
NCT00302211 - Terminated(Terminated due to s... More >>low enrollment) Less << - -
NCT00084409 Lung Cancer P... More >>recancerous Condition Less << Phase 2 Completed - United States, Colorado ... More >> University of Colorado Cancer Center at UC Health Sciences Center Aurora, Colorado, United States, 80045 Veterans Affairs Medical Center - Denver Denver, Colorado, United States, 80220 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231-2410 United States, Minnesota Mayo Clinic Cancer Center Rochester, Minnesota, United States, 55905 United States, Pennsylvania UPMC Cancer Centers Pittsburgh, Pennsylvania, United States, 15232 United States, Tennessee Vanderbilt-Ingram Cancer Center Nashville, Tennessee, United States, 37232-6838 Less <<
NCT01712997 Pulmonary Arterial Hypertensio... More >>n Less << Phase 3 Unknown - China, Shaanxi ... More >> The department of pulmonary and critical care medicine, Tangdu hospital Recruiting Xi'an, Shaanxi, China, 710032 Contact: Yonghong Xie, MD    +86-29-84777725    xieyh65@yahoo.com.cn    Principal Investigator: Yonghong Xie, MD          The department of pulmonary and critical care medicine, Xijing hospital Recruiting Xi'an, Shaanxi, China, 710032 Contact: Xinpeng Han, MD    +86-29-84775237    hxp0728@163.com    Sub-Investigator: Xinpeng Han, MD          Sub-Investigator: Yongping Yu, MD Less <<
NCT02170519 Pulmonary Hypertension Phase 4 Terminated(Project was complet... More >>ed) Less << - -
NCT00302211 Pulmonary Hypertension Phase 3 Terminated(Terminated due to s... More >>low enrollment) Less << - -
NCT02170519 - Terminated(Project was complet... More >>ed) Less << - -
NCT00453414 Pulmonary Arterial Hypertensio... More >>n Less << Phase 2 Withdrawn(Withdrawn due to lac... More >>k of enrollment) Less << October 2006 United States, Colorado ... More >> The Children's Hospital Denver, Colorado, United States, 80218 United States, New York Columbia University Medical Center New York, New York, United States, 10032 Less <<
NCT01469169 Hypertension, Pulmonary Phase 3 Completed - Japan ... More >> Nagoya, Aichi, Japan, 466-8560 Nagoya, Aichi, Japan, 467-8602 Kurume, Fukuoka, Japan, 830-0011 Asahikwa, Hokkaido, Japan, 078-8510 Kobe, Hyogo, Japan, 650-0017 Kawasaki, Kanagawa, Japan, 216-8511 Sendai, Miyagi, Japan, 980-8574 Tomigusuku, Okinawa, Japan, 901-0243 Bunkyo-ku, Tokyo, Japan, 113-8655 Chuoku, Tokyo, Japan, 104-8560 Mitaka, Tokyo, Japan, 181-8611 Ota-ku, Tokyo, Japan, 143-8541 Shinjuku-ku, Tokyo, Japan, 160-8582 Shinjuku-ku, Tokyo, Japan, 162-8655 Tanabe, Wakayama, Japan, 646-8558 Ube, Yamaguchi, Japan, 755-8505 Chiba, Japan, 260-8677 Tokushima, Japan, 770-8503 Less <<
NCT00439543 Pulmonary Fibrosis ... More >> Pulmonary Hypertension Less << Phase 2 Phase 3 Unknown - Korea, Republic of ... More >> Pulmonary Medicine, Asan Medical Center, Ulsan University Not yet recruiting Seoul, Korea, Republic of, 138-736 Principal Investigator: Dong Soon Kim, MD Less <<
NCT00185315 Hypertension, Pulmonary Phase 3 Completed - Belgium ... More >> Bruxelles, Belgium, 1070 Leuven, Belgium, 3000 France Clamart Cedex, France, 92141 Grenoble Cedex 9, France, 38043 Lille, France, 59037 Reims, France, 51092 Tours Cedex, France, 37044 Italy Bologna, BO, Italy, 40138 Montescano, Pavia, Italy, 27040 Pisa, PI, Italy, 56100 Netherlands Amsterdam, Netherlands, 1081 HV Poland Warszawa, Poland, 01138 Portugal Coimbra, Portugal, 3000-076 Vila Nova de Gaia, Portugal, 4434-506 Spain Barcelona, Spain, 08035 Madrid, Spain, 28041 Less <<
NCT01355380 - Completed - Poland ... More >> Many Locations, Poland Less <<
NCT00622687 Systemic Sclerosis Phase 2 Terminated(sufficient number t... More >>o reach the primary endpoint and as planned) Less << - Germany ... More >> Charrité Universitätsmedizin Berlin, Germany, 10117 Less <<
NCT02784899 Lung Cancer Not Applicable Completed - Korea, Republic of ... More >> Department of Anaesthesiology and Pain Medicine, Anaesthesia and Pain Research Institute, Yonsei University College of Medicine Seoul, Korea, Republic of, 03722 Less <<
NCT00084409 - Completed - -
NCT00345501 Renal Insufficiency, Chronic ... More >> Coronary Angiography Angioplasty, Transluminal, Percutaneous Coronary Less << Phase 2 Phase 3 Completed - Greece ... More >> Onassis Cardiac Surgery Centre Athens, Greece, 17674 Less <<
NCT01310751 Pulmonary Hypertension Phase 2 Phase 3 Completed - China ... More >> Cardiac intensive Care Unit,Department of Thoracic and Cardiovascular Sugery,Shanghai Children's Medical Center Shanghai, China, 200127 Less <<
NCT03293407 - Recruiting July 31, 2019 Germany ... More >> Many Locations Recruiting Multiple Locations, Germany Less <<
NCT02204852 Septic Shock Phase 2 Completed - Denmark ... More >> Department of Anesthesia and Intensive Care, Nordsjællands Hospital Hillerød, Capital Region, Denmark, DK-3400 Less <<
NCT01116063 Chronic Obstructive Pulmonary ... More >>Disease Less << Phase 4 Unknown June 2013 Israel ... More >> Pulmoanry Division, Carmel Medical Center Not yet recruiting Haifa, Israel Contact: Yochai Adir, MD    972-4-8250517    yochaiad@clalit.org.il    Principal Investigator: Yochai Adir, MD Less <<
NCT00235521 Pulmonary Hypertension Not Applicable Completed - Germany ... More >> University of Heidelberg, Medical Faculty, Department of Pediatric Cardiology Heidelberg, Germany, 69120 Less <<
NCT01549171 - Unknown December 2013 United States, Texas ... More >> Fertility Specialists of Houston Recruiting Houston, Texas, United States, 77054 Contact: Wan-Song A Wun, Ph.D.    713-512-7680    awun@obgynassociates.com    Contact: George M Grunert, M.D.    713-512-7760    ggrunert@fshivf.com    Sub-Investigator: Randall C Dunn, M.D.          Sub-Investigator: Schenk M Leah, M.D.          Sub-Investigator: Mangal K Rakesh, M.D.          Sub-Investigator: Chauhan R Subodh, M.D.          Sub-Investigator: Wan-Song A Wun, Ph.D. Less <<
NCT01781052 - Completed - France ... More >> Multiple Locations, France Less <<
NCT01458041 - Completed - Hungary ... More >> Many locations, Hungary Less <<
NCT01383083 - Unknown November 2012 -
NCT00409526 Pulmonary Hypertension Phase 4 Terminated(Sub-Investigator le... More >>ft U of C) Less << - United States, Illinois ... More >> Comer Children's Hospital, The University of Chicago Hospitals Chicago, Illinois, United States, 60637 Israel Shaare Zedek Medical Center Jerusalem, Israel, 91031 Less <<
NCT02237183 Cytologic Atypia ... More >> Former Smoker Mild Dysplasia Less << Phase 1 Recruiting - United States, Colorado ... More >> University of Colorado Recruiting Denver, Colorado, United States, 80217-3364 Contact: York E. Miller    303-393-2896    york.miller@ucdenver.edu    Principal Investigator: York E. Miller Less <<
NCT01894035 - Completed - Portugal ... More >> Multiple Locations, Portugal Less <<
NCT00403650 Sarcoidosis|Pulmonary Arterial... More >> Hypertension Less << PHASE4 COMPLETED 2025-09-08 University of Cincinnati, Cinc... More >>innati, Ohio, 45267, United States Less <<
NCT00709956 Pulmonary Arterial Hypertensio... More >>n Less << Phase 3 Completed - -
NCT00927654 Pulmonary Hypertension Phase 3 Completed - Germany ... More >> Hospital of the university of Aachen Aachen, Germany, 52074 Herz- und Diabeteszentrum NRW Bad Oeynhausen, Germany, 32545 Deutsches Herzzentrum Berlin Berlin, Germany, 13353 Hospital of the university of Duesseldorf Duesseldorf, Germany, 40225 Hospital of the university of Frankfurt Frankfurt, Germany, 60590 Hospital of the university of munich Munich, Germany, 81377 Less <<
NCT02825160 - Recruiting September 27, 2023 Japan ... More >> Many Locations Recruiting Multiple Locations, Japan Less <<
NCT01320878 Pulmonary Hypertension Phase 2 Completed - China ... More >> Cardiac intensive Care Unit,Department of Thoracic and Cardiovascular Sugery,Shanghai Children's Medical Center Shanghai, China, 200127 Less <<
NCT01437878 Chronic Obstructive Pulmonary ... More >>Disease Pulmonary Hypertension Less << Phase 2 Terminated(low recruitment) - United States, California ... More >> Los Angeles Biomedical Research Institute Torrance, California, United States, 90502 United States, Florida Mayo Clinic Jacksonville Jacksonville, Florida, United States, 32224 United States, Illinois Northwestern University Chicago, Illinois, United States, 60611 United States, Louisiana Ochsner Clinic Foundation New Orleans, Louisiana, United States, 70112 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114 United States, Ohio Cleveland Clinic Cleveland, Ohio, United States, 44195 United States, Oklahoma University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma, United States, 73104 United States, Pennsylvania Temple University Hospital Philadelphia, Pennsylvania, United States, 19140 University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 France Hopital d'adultes de Brabois Vandoeuvre-lès-Nancy, France, 54500 Spain Hospital Clinic i Provincial Barcelona, Spain, 08036 Less <<
NCT01437878 - Terminated(low recruitment) - -
NCT01941225 Chronic Obstructive Pulmonary ... More >>Disease Less << Phase 2 Completed - United States, Louisiana ... More >> LSU Health Sciences Center New Orleans, Louisiana, United States, 70125 Less <<
NCT03111212 Respiratory Distress Syndrome,... More >> Adult Less << Phase 3 Not yet recruiting September 2021 Germany ... More >> University Hospital Tuebingen Not yet recruiting Tuebingen, Germany, 72076 Contact: Peter Rosenberger, MD       peter.rosenberger@med.uni-tuebingen.de    Contact: Helene A Haeberle, MD       helene.haeberle@med.uni-tuebingen.de    Sub-Investigator: Helene A Haeberle, MD          Principal Investigator: Peter Rosenberger, MD Less <<
NCT00709956 - Completed - -
NCT00724321 Hypoxic Pulmonary Vasoconstric... More >>tion Less << Phase 1 Withdrawn(PI has left the inst... More >>itution. We are unable to locate any study records to determine if subjects were enrolled.) Less << - United States, California ... More >> Loma Linda University Loma Linda, California, United States, 92354 Less <<
NCT01598441 Pulmonary Hypertension Phase 3 Completed - China, Guangdong ... More >> Guangzhou Children's Hospital Guangzhou, Guangdong, China, 510000 China, Hubei Wuhan Asia Hear Hospital Wuhan, Hubei, China, 430022 China Cardiac intensive Care Unit,Department of Thoracic and Cardiovascular Sugery,Shanghai Children's Medical Center Shanghai, China, 200127 Less <<
NCT00708565 Hypoxic Pulmonary Vasoconstric... More >>tion Less << Phase 1 Unknown October 2008 United States, California ... More >> Jerry L. Pettis VA Medical Center Recruiting Loma Linda, California, United States, 92357 Contact: James D Anholm, MD    909-583-6098    James.Anholm@va.gov Less <<
NCT02482402 Chronic Left Ventricular Failu... More >>re Pulmonary Hypertension Less << Phase 2 Withdrawn(Delay in recruitment... More >>) Less << - Germany ... More >> Klinik für Thorax- und Kardiovaskularchirurgie Bad Oeynhausen, Germany, 32545 Thoraxclinic at the University of Heidelberg Heidelberg, Germany, 69126 Less <<
NCT00902603 - Terminated(low enrollment and ... More >>difficulty recruiting eligible patients in adequate time) Less << - -
NCT01319045 Pulmonary Arterial Hypertensio... More >>n|Congenital Heart Disease|Eisenmenger's Syndrome Less << TERMINATED 2025-05-13 Ronald Reagan UCLA Medical Cen... More >>ter, Los Angeles, California, 90095, United States Less <<
NCT00709098 Pulmonary Arterial Hypertensio... More >>n Less << Phase 3 Completed - -
NCT01209533 Asthma EARLY_PHASE1 COMPLETED 2025-07-11 Vanderbilt University Medical ... More >>Center, Nashville, Tennessee, 37064, United States Less <<
NCT00981591 Pulmonary Hypertension ... More >> Neonatal Hypoxic Respiratory Failure Persistent Pulmonary Hypertension of Newborn Congenital Heart Defects Acute Respiratory Distress Syndrome Less << Phase 1 Phase 2 Withdrawn(No patients recruite... More >>d) Less << - -
NCT00561223 Chronic Obstructive Pulmonary ... More >>Disease Pulmonary Hypertension Less << Not Applicable Completed - United States, Oklahoma ... More >> University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma, United States, 73104 Less <<
NCT00467896 Pulmonary Hypertension Phase 2 Terminated(Sponsor's decision) - United States, Arizona ... More >> Pulmonary Associates Phoenix, Arizona, United States, 85006 United States, California UCSD Medical Center, Thorton Hospital La Jolla, California, United States, 92037 United States, Iowa University of Iowa Hospital and Clinics Iowa City, Iowa, United States, 52242 United States, Louisiana Ochsner Clinic Foundation New Orleans, Louisiana, United States, 70112 United States, Maryland University of Maryland Hospital Baltimore, Maryland, United States, 21201 United States, New York Columbia University Medical Center New York, New York, United States, 10032 New York Presbyterian Hospital New York, New York, United States, 10032 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Pennsylvania University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 United States, Texas Baylor College of Medicine Houston, Texas, United States, 77030 Diagnostic Research Group San Antonio, Texas, United States, 78229 United States, Wisconsin Aurora Medical Group - Cardiovascular Services Milwaukee, Wisconsin, United States, 53215 Less <<
NCT01319045 Pulmonary Arterial Hypertensio... More >>n|Congenital Heart Disease|Eisenmenger's Syndrome Less << TERMINATED 2025-05-13 Ronald Reagan UCLA Medical Cen... More >>ter, Los Angeles, California, 90095, United States Less <<
NCT00723554 Pulmonary Arterial Hypertensio... More >>n Less << Phase 3 Terminated(sponsor's decision) - -
NCT00467896 - Terminated(Sponsor's decision) - -
NCT01274481 Acute Respiratory Distress Syn... More >>drome|Acute Lung Injury|Pulmonary Hypertension Less << PHASE1 COMPLETED 2025-07-12 OU Medical Center, Oklahoma Ci... More >>ty, Oklahoma, 73104, United States Less <<
NCT03380325 Diabetes Mellitus, Type 2 ... More >> Insulin Sensitivity/Resistance Less << Not Applicable Completed - Netherlands ... More >> VU University Medical Center Amsterdam, Noord-Holland, Netherlands, 1081 HV Less <<
NCT00723554 - Terminated(sponsor's decision) - -
NCT00709098 - Completed - -
NCT03620526 Heart Failure With Normal Ejec... More >>tion Fraction Less << Phase 4 Recruiting September 1, 2018 Taiwan ... More >> National Taiwan University Hospital Recruiting Taipei, Taiwan, 100 Contact: CHO-KAI WU, MD, PhD Less <<
NCT02826252 - Completed - Germany ... More >> Many locations, Germany Less <<
NCT03044314 Pulmonary Hypertension Phase 4 Recruiting December 1, 2020 United States, North Carolina ... More >> Duke University Health System Recruiting Durham, North Carolina, United States, 27710 Contact: Richard A Krasuski, MD    919-684-2407    richard.krasuski@duke.edu    Contact: Stephanie Newbold, MS    919-613-4728    stephanie.newbold@duke.edu    Sub-Investigator: Jordan Awerbach, MD Less <<
NCT03365479 Pulmonary Hypertension|Pulmona... More >>ry Arterial Hypertension Less << COMPLETED 2018-10-24 University Clinic Giessen and ... More >>Marburg, Giessen, Hesse, 35392, Germany|Kerckhoff-Klinik, Bad Nauheim, Germany Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.77mL

0.55mL

0.28mL

13.87mL

2.77mL

1.39mL

27.74mL

5.55mL

2.77mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

Historical Records

Categories