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Chemical Structure| 288628-05-7 Chemical Structure| 288628-05-7

Structure of Irosustat
CAS No.: 288628-05-7

Chemical Structure| 288628-05-7

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Irosustat is a potent, irreversible inhibitor of steroid sulfatase.

Synonyms: STX64; BN83495; COUMATE. Irosustat.

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Product Details of Irosustat

CAS No. :288628-05-7
Formula : C14H15NO5S
M.W : 309.34
SMILES Code : O=S(OC1=CC(O2)=C(C=C1)C(CCCCC3)=C3C2=O)(N)=O
Synonyms :
STX64; BN83495; COUMATE. Irosustat.
MDL No. :MFCD12912443
InChI Key :DSLPMJSGSBLWRE-UHFFFAOYSA-N
Pubchem ID :5287541

Safety of Irosustat

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01662726 Breast Neoplasms PHASE2 TERMINATED 2025-12-14 Imperial College Healthcare NH... More >>S Trust, London, W6 8RF, United Kingdom Less <<
NCT01785992 Locally Advanced Breast Cancer... More >>|Metastatic Breast Cancer Less << PHASE2 COMPLETED 2025-12-14 Mid Essex Hospital Services NH... More >>S Trust, Chelmsford, CM1 7ET, United Kingdom|NHS Lothian, Edinburgh, EH1 3EG, United Kingdom|NHS Greater Glasgow and Clyde, Glasgow, G12 0YN, United Kingdom|Royal Liverpool and Broadgreen University Hospital, Liverpool, L7 8XP, United Kingdom|Royal Free London, London, NW3 2QG, United Kingdom|West Middlesex University Hospital NHS Trust, London, TW7 6AF, United Kingdom|Imperial College Healthcare NHS Trust, London, W6 8RF, United Kingdom|University College London Hospitals NHS Foundation Trust, London, WC1E 6BT, United Kingdom|The Christie NHS Foundations Trust, Manchester, M204BX, United Kingdom Less <<
NCT01230970 Breast Cancer PHASE2 TERMINATED 2025-05-11 Akershus University Hospital, ... More >>L?renskog, 1474, Norway Less <<
NCT01251354 Endometrial Cancer PHASE2 TERMINATED 2025-07-11 Dept of Obstetrics and Gynecol... More >>ogy, Medical College of Georgia, Augusta, Georgia, 30912, United States|Division of Gynecologic Oncology, University of Minnesota Medical Center, Minneapolis, Minnesota, 55455, United States|Jordan Center for Gynecologic Cancer at Penn, University of Pennsylvania, Philadelphia, Pennsylvania, 19104-4283, United States|Crozer Chester medical Center, Upland, Pennsylvania, 19103, United States|London Health Sciences Centre, University of Western Ontario, London, Ontario, N6A 4L6, Canada|Department of Oncology, Ottawa Cancer Center, Ottawa, Ontario, K1H 8L6, Canada|Dept of Obstetrics and Gynecology, Princess Margaret Hospital, Toronto, Ontario, M5G 2M9, Canada|CHUM-Hospital Notre-Dame Service de Gynecologic Oncologique, Montreal, Quebec, H2L 4M1, Canada|Department of Oncology, McGill University, Montreal, Quebec, H2W 1S6, Canada Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.23mL

0.65mL

0.32mL

16.16mL

3.23mL

1.62mL

32.33mL

6.47mL

3.23mL

References

 

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