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Chemical Structure| 129280-34-8 Chemical Structure| 129280-34-8

Structure of Isoangustone A
CAS No.: 129280-34-8

Chemical Structure| 129280-34-8

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Isoangustone A, a natural product isolated and purified from the roots of Licorice with antitumor activity, induces G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, dampens mesangial sclerosis associated with inflammation in response to high glucose through hindering TGF-β and NF-κB signaling, inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma and shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet oxygen radicals.

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Product Details of Isoangustone A

CAS No. :129280-34-8
Formula : C25H26O6
M.W : 422.47
SMILES Code : O=C1C(C2=CC(C/C=C(C)\C)=C(O)C(O)=C2)=COC3=CC(O)=C(C/C=C(C)\C)C(O)=C13
InChI Key :QNLGNISMYMFVHP-UHFFFAOYSA-N
Pubchem ID :21591148

Safety of Isoangustone A

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Isoangustone A

MAPK
PI3K-AKT

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.37mL

0.47mL

0.24mL

11.84mL

2.37mL

1.18mL

23.67mL

4.73mL

2.37mL

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