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Chemical Structure| 2445499-20-5 Chemical Structure| 2445499-20-5

Structure of JAK-IN-21
CAS No.: 2445499-20-5

Chemical Structure| 2445499-20-5

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JAK-IN-21 is a selective and potent JAK inhibitor with IC50 values of 1.73, 2.04, 109, and 62.9 nM for JAK1, JAK2, J2V617F, and TYK2, respectively.

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Product Details of JAK-IN-21

CAS No. :2445499-20-5
Formula : C19H16N8O
M.W : 372.38
SMILES Code : O=C(NCC#N)C1=CC=C(C2=NC(NC3=CN(CC#N)N=C3)=NC=C2C)C=C1
MDL No. :N/A

Safety of JAK-IN-21

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of JAK-IN-21

epigenetics
RTK
JAK-STAT

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.69mL

0.54mL

0.27mL

13.43mL

2.69mL

1.34mL

26.85mL

5.37mL

2.69mL

 

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