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Chemical Structure| 99624-27-8 Chemical Structure| 99624-27-8

Structure of Kazinol B
CAS No.: 99624-27-8

Chemical Structure| 99624-27-8

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Kazinol B, a natural product isolated and purified from the barks of Broussonetia papyrifera, inhibits the NO synthesis with an IC(50) of 21.6 mM, stimulates respiratory burst, is probably mediated by the synergism of PKC activation and [Ca2+]i elevation in rat neutrophils, stimulates Ca(2+) release from internal Ca(2+) store, probably through the sphingosine 1-phosphate and IP(3) signaling, activates external Ca(2+) influx mainly through a non-store-operated Ca(2+) entry (non-SOCE) pathway, and inhibits SOCE, probably attributable to a break in the Ca(2+) driven force of mitochondria.

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Product Details of Kazinol B

CAS No. :99624-27-8
Formula : C25H28O4
M.W : 392.49
SMILES Code : OC1=CC=C2CC[C@@H](C3=C(C/C=C(C)\C)C(O)=C4C(C=CC(C)(C)O4)=C3)OC2=C1

Safety of Kazinol B

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Kazinol B

epigenetics
PI3K-AKT

Isoform Comparison

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Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.55mL

0.51mL

0.25mL

12.74mL

2.55mL

1.27mL

25.48mL

5.10mL

2.55mL

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