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Chemical Structure| 126643-37-6 Chemical Structure| 126643-37-6

Structure of KT5823
CAS No.: 126643-37-6

Chemical Structure| 126643-37-6

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KT 5823 is a selective inhibitor of the cGMP-dependent protein kinase (PKG) (Ki values are 0.23, 4 and > 10 μM for inhibition of PKG, PKC and PKA respectively). KT 5823 inhibits SNP-stimulated PKG activity with an IC50 of 60 nM in dispersed smooth muscle cells and has little effect on PKA activity at concentrations of up to 10 μM.

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Product Details of KT5823

CAS No. :126643-37-6
Formula : C29H25N3O5
M.W : 495.53
SMILES Code : C[C@]12O[C@@H](N3C4=CC=CC=C4C5=C3C6=C(C7=CC=CC=C7N26)C8=C5C(N(C)C8)=O)C[C@@]1(C(OC)=O)OC
MDL No. :MFCD09878278

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Related Pathways of KT5823

epigenetics
Hedgehog

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