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Chemical Structure| 819812-04-9 Chemical Structure| 819812-04-9

Structure of KW-2478
CAS No.: 819812-04-9

Chemical Structure| 819812-04-9

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KW-2478 is a nonansamycin HSP90 inhibitor with IC50 of 3.8 nM.

4.5 *For Research Use Only !

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Product Details of KW-2478

CAS No. :819812-04-9
Formula : C30H42N2O9
M.W : 574.66
SMILES Code : O=C(N(CCOC)CCOC)CC1=C(C(C2=CC=C(OCCN3CCOCC3)C(OC)=C2)=O)C(O)=CC(O)=C1CC
MDL No. :MFCD21609267
InChI Key :VFUXSYAXEKYYMB-UHFFFAOYSA-N
Pubchem ID :23116322

Safety of KW-2478

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Related Pathways of KW-2478

DNA

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00457782 Multiple Myeloma|Chronic Lymph... More >>ocytic Leukaemia|B-cell Non-Hodgkin's Lymphoma Less << PHASE1 COMPLETED 2025-01-11 St Bartholomew's Hospital, Lon... More >>don, United Kingdom|UCLH, London, United Kingdom|Christie Hospital, Manchester, United Kingdom|Nottingham University NHS Trust, Nottingham, United Kingdom|Cancer Research UK Clinical Centre, Southampton, United Kingdom|Royal Marsden Hospital, Sutton, United Kingdom Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.74mL

0.35mL

0.17mL

8.70mL

1.74mL

0.87mL

17.40mL

3.48mL

1.74mL

References

 

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