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Chemical Structure| 1228280-29-2 Chemical Structure| 1228280-29-2

Structure of KY-05009
CAS No.: 1228280-29-2

Chemical Structure| 1228280-29-2

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Inhibitor of Traf2- and Nck-Interacting Kinase (TNIK; Ki value 100 nM in ATP competitive assay) that attenuates TGF-β1-mediated Wnt and Smad signaling and epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma A549 cells. Additionally, KY05009 inhibits TGF-β1-induced phosphorylation of JNK1/2, FAK, Src, and paxillin.

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Product Details of KY-05009

CAS No. :1228280-29-2
Formula : C18H16N4O2S
M.W : 352.41
SMILES Code : O=C(C1=C(NC(C2=CC=C(C)C=C2)=O)SC(NC3=CC=CC=C3)=N1)N
MDL No. :MFCD29059915
InChI Key :WCEDGRTWDSHZHF-UHFFFAOYSA-N
Pubchem ID :46234348

Safety of KY-05009

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.84mL

0.57mL

0.28mL

14.19mL

2.84mL

1.42mL

28.38mL

5.68mL

2.84mL

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