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Chemical Structure| 203120-17-6 Chemical Structure| 203120-17-6

Structure of Laninamivir
CAS No.: 203120-17-6

Chemical Structure| 203120-17-6

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Laninamivir is a neuraminidase inhibitor that exhibits clinical efficacy for both treatment and prophylaxis of influenza virus infection, resulting from hydrolytic bioactivation into its pharmacologically active metabolite laninamivir in the pulmonary tissue.

Synonyms: R 125489

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Product Details of Laninamivir

CAS No. :203120-17-6
Formula : C13H22N4O7
M.W : 346.34
SMILES Code : OC[C@@H](O)[C@H]([C@@]1([H])[C@@H]([C@H](C=C(O1)C(O)=O)NC(N)=N)NC(C)=O)OC
Synonyms :
R 125489
MDL No. :MFCD18071611
InChI Key :QNRRHYPPQFELSF-CNYIRLTGSA-N
Pubchem ID :502272

Safety of Laninamivir

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Isoform Comparison

Biological Activity

Description
Laninamivir (R 125489) exhibits potent inhibition of influenza neuraminidase (NA), demonstrating IC50 values of 0.90 nM, 1.83 nM, and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1), and A/RI/5+/1957 H2N2 N2 (p57N2), respectively [1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.89mL

0.58mL

0.29mL

14.44mL

2.89mL

1.44mL

28.87mL

5.77mL

2.89mL

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