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Chemical Structure| 130209-82-4 Chemical Structure| 130209-82-4

Structure of Latanoprost
CAS No.: 130209-82-4

Chemical Structure| 130209-82-4

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Latanoprost is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.

Synonyms: PHXA41; 17-phenyl-13,14-dihydro trinor Prostaglandin F2α isopropyl ester; Xalatan

4.5 *For Research Use Only !

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Product Details of Latanoprost

CAS No. :130209-82-4
Formula : C26H40O5
M.W : 432.59
SMILES Code : O=C(CCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)CC[C@H](CCC2=CC=CC=C2)O)OC(C)C
Synonyms :
PHXA41; 17-phenyl-13,14-dihydro trinor Prostaglandin F2α isopropyl ester; Xalatan
MDL No. :MFCD00216074
InChI Key :GGXICVAJURFBLW-CEYXHVGTSA-N
Pubchem ID :5311221

Safety of Latanoprost

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H361
Precautionary Statements:P201-P202-P264-P270-P280-P301+P310-P308+P313-P330-P405-P501
Class:6.1
UN#:2810
Packing Group:

Related Pathways of Latanoprost

GPCR

Isoform Comparison

Biological Activity

Description
Latanoprost (PHXA41) is a prostaglandin F2α analogue utilized in glaucoma research. It can penetrate the cornea and is metabolized by esterase into latanoprost acid. Latanoprost acid acts as an F-prostaglandin (FP) receptor agonist, effectively lowering intraocular pressure (IOP) by enhancing aqueous humor outflow through the uvea[1].

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00442312 Glaucoma Phase 4 Unknown - Taiwan ... More >> Allergan Taipei, Taiwan Less <<
NCT03762369 Primary Open-angle Glaucoma ... More >> Ocular Hypertension Less << Phase 3 Not yet recruiting May 30, 2022 Korea, Republic of ... More >> Seoul National University Hosipital Seoul, Jongno, Korea, Republic of Less <<
NCT01433900 Glaucoma Phase 3 Unknown June 2014 Italy ... More >> San Paolo Hospital Recruiting Milano, Italy, 20142 Principal Investigator: Luca Rossetti, MD          Principal Investigator: Paolo Fogagnolo, MD Less <<
NCT01525173 - Completed - -
NCT01525173 Glaucoma Ocul... More >>ar Hypertension Less << Phase 4 Completed - United States, Florida ... More >> Deerfield Beach, Florida, United States Less <<
NCT00846989 Glaucoma Ocul... More >>ar Hypertension Less << Phase 1 Phase 2 Completed - -
NCT01084902 Ocular Hypertension Not Applicable Unknown December 2010 -
NCT01060579 Glaucoma Phase 2 Completed - United States, California ... More >> United Medical Research Institute Inglewood, California, United States, 90301 North Bay Eye Associates Petaluma, California, United States, 94954 Centre For Health Care Poway, California, United States, 92064 United States, Florida East Florida Eye Institute Stuart, Florida, United States, 34994 Marvin Greenberg, MD Tamarac, Florida, United States, 33321 United States, Georgia Coastal Research Associates, LLC Roswell, Georgia, United States, 30076 United States, Kansas Bradley Kwapiszeski, MD Shawnee Mission, Kansas, United States, 66204 United States, Kentucky Taustine Eye Center Louisville, Kentucky, United States, 40217 United States, Missouri Comprehensive Eye Care St Louis, Missouri, United States, 63090 United States, New York Mount Sinai School Of Medicine New York, New York, United States, 10029 Rochester Ophthalmology Group Rochester, New York, United States, 14618 Glaucoma Consultants of the Capital Region Slingerlands, New York, United States, 12159 United States, North Carolina Charlotte Eye Ear Nose and Throat Charlotte, North Carolina, United States, 28210 United States, Oklahoma The Eye Institute Tulsa, Oklahoma, United States, 74104 United States, South Dakota Black Hills Regional Eye Institute Rapid City, South Dakota, United States, 57701 United States, Tennessee Univ Eye Surgeons, Maryville Ctr. Maryville, Tennessee, United States, 37803 United States, Texas Texan Eye Austin, Texas, United States, 78731 Medical Center Ophth. Associates San Antonio, Texas, United States, 78731 Less <<
NCT02108288 Glaucoma Ocul... More >>ar Hypertension Less << Phase 1 Completed - Japan ... More >> Kansai Region, Japan Less <<
NCT02108288 - Completed - -
NCT00967811 Glaucoma Ocul... More >>ar Hypertension Less << Phase 2 Completed - United States, California ... More >> Menlo Park, California, United States, 94025 Less <<
NCT03274323 Glaucoma, Open-Angle Not Applicable Withdrawn(Difficulty obtaining... More >> IDE by the FDA. Currently not worthwhile to pursue further.) Less << - -
NCT00751049 Ocular Hypertension ... More >> Open Angle Glaucoma Less << Phase 3 Completed - United Kingdom ... More >> Pfizer Investigational Site Aberdeen, Grampian, United Kingdom, AB25 2ZD Pfizer Investigational Site Nottingham, Notts., United Kingdom, NG7 2UH Pfizer Investigational Site Bristol, United Kingdom, BS1 2LX Pfizer Investigational Site Cambridge, United Kingdom Pfizer Investigational Site Cardiff, United Kingdom, CF4 4XW Pfizer Investigational Site Dundee, United Kingdom, DD2 9SY Pfizer Investigational Site Liverpool, United Kingdom, L7 8XP Pfizer Investigational Site London, United Kingdom, NW3 2QG Pfizer Investigational Site London, United Kingdom Pfizer Investigational Site Manchester, United Kingdom Pfizer Investigational Site Paisley, United Kingdom Pfizer Investigational Site Sheffield, United Kingdom, S10 2JF Less <<
NCT00811564 Glaucoma Ocul... More >>ar Hypertension Less << Phase 4 Completed - United States, New York ... More >> Slingerlands, New York, United States Less <<
NCT00811564 - Completed - -
NCT00304785 Open-Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 4 Completed - Poland ... More >> Gabinety Okulistyczne Bydgoszcz, Poland, PL-85-670 Kierownik Kliniki Okulistycznej Akademii Medycznej Poznan', Poland, PL-61-848 Instytut Jaskry Warsaw, Poland, 00415 Katdra Klinika Okulityki Akademii Medycznej w Warszawie Warsaw, Poland, 02-005 Ordynator Oddziału Okulistycznego Międzyleski Szpital Specjalistyczny Warszawa, Poland, PL-04-749 Less <<
NCT00348400 Glaucoma Phase 4 Completed - United States, Pennsylvania ... More >> Dr. Noecker Pittsburgh, Pennsylvania, United States, 15213 Less <<
NCT00751062 Open Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 3 Completed - Denmark ... More >> Pfizer Investigational Site Hellerup, Denmark Pfizer Investigational Site Vejle, Denmark Finland Pfizer Investigational Site Oulu, Finland Norway Pfizer Investigational Site Bergen, Norway Pfizer Investigational Site Oslo, Norway Pfizer Investigational Site Trondheim, Norway Sweden Pfizer Investigational Site Gothenburg, Sweden Pfizer Investigational Site Huddinge, Sweden, 141 86 Pfizer Investigational Site Linkoping, Sweden, 581 85 Pfizer Investigational Site Lund, Sweden Pfizer Investigational Site Malmo, Sweden, 205 02 Pfizer Investigational Site Umea, Sweden Pfizer Investigational Site Uppsala, Sweden Less <<
NCT00596791 Ocular Hypertension ... More >> Open-Angle Glaucoma Less << Phase 3 Completed - Finland ... More >> Finn-Medi Research Oy Tampere, Finland, 33520 Less <<
NCT00440141 Glaucoma Ocul... More >>ar Hypertension Less << Phase 4 Completed - United States, Georgia ... More >> Atlanta, Georgia, United States Less <<
NCT01087671 Ocular Hypertension ... More >> Open-Angle Glaucoma Less << Phase 3 Completed - -
NCT00705757 - Completed - -
NCT01254370 Glaucoma Ocul... More >>ar Hypertension Ocular Surface Disease Less << Phase 2 Completed - United States, Massachusetts ... More >> Ora (Ophthalmic Research Associates) Andover, Massachusetts, United States, 01810 Less <<
NCT02278614 Open Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 3 Completed - France ... More >> Laboratoires Thea Clermont ferrand, France, 63017 Less <<
NCT01037036 Ocular Hypertension ... More >> Open-Angle Glaucoma Less << Phase 2 Completed - United States, California ... More >> Menlo Park Menlo Park, California, United States, 94025 Less <<
NCT00347126 - Completed - Singapore ... More >> Singapore National Eye Centre Singapore, Singapore, 168751 Less <<
NCT02278614 - Completed - -
NCT00803387 - Completed - United States, Texas ... More >> WHMC Lackland AFB, Texas, United States, 78236 Less <<
NCT00705757 Glaucoma Appl... More >>ication Site Pigmentation Changes Less << Phase 4 Completed - United States, Illinois ... More >> Arlington Eye Physicians Arlington Heights, Illinois, United States, 60005 United States, Ohio Summa Health System Akron, Ohio, United States, 44304 Less <<
NCT00934089 Glaucoma, Open-Angle ... More >> Ocular Hypertension Less << Phase 2 Completed - United States, California ... More >> Pfizer Investigational Site Cypress, California, United States, 90630 Pfizer Investigational Site Garden Grove, California, United States, 92844 Pfizer Investigational Site Gardena, California, United States, 90247 Pfizer Investigational Site Long Beach, California, United States, 90806 Pfizer Investigational Site Los Angeles, California, United States, 90013 Pfizer Investigational Site Los Angeles, California, United States, 90057 Pfizer Investigational Site Newport Beach, California, United States, 92663 Pfizer Investigational Site Pasadena, California, United States, 91105 Less <<
NCT00402493 Glaucoma Ocul... More >>ar Hypertension Less << Not Applicable Completed - United States, New Jersey ... More >> Philadelphia Eye Associates Willingboro, New Jersey, United States, 08046 United States, Pennsylvania Philadelphia Eye Associates Philadelphia, Pennsylvania, United States, 19134 Philadelphia Eye Associates Philadelphia, Pennsylvania, United States, 19148 Less <<
NCT00051142 Glaucoma, Open-Angle ... More >> Ocular Hypertension Less << Phase 3 Completed - United States, Texas ... More >> Latin America Fort Worth, Texas, United States Less <<
NCT00051181 Glaucoma, Angle-Closure ... More >> Ocular Hypertension Less << Phase 3 Completed - United States, Texas ... More >> Asia Fort Worth, Texas, United States Australia Australia Sidney, Australia Less <<
NCT03284853 Open Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 3 Recruiting November 2019 -
NCT00821002 Open-Angle Glaucoma|Ocular Hyp... More >>ertension Less << PHASE2 COMPLETED 2025-11-09 Menlo Park, California, 94025,... More >> United States Less <<
NCT01302249 Glaucoma Ocul... More >>ar Hypertension Less << Phase 2 Completed - United States, Connecticut ... More >> David Silverstone, M.D. New Haven, Connecticut, United States, 06510 United States, Georgia Coastal Research Associates, LLC Roswell, Georgia, United States, 30076 United States, Kansas Heart of America Eye Care, P.A. Shawnee Mission, Kansas, United States, 66204 United States, Kentucky Taustine Eye Center Louisville, Kentucky, United States, 40217 United States, Maryland Alan L Robin, M.D. Baltimore, Maryland, United States, 21209 United States, Missouri Comprehensive Eye Care St Louis, Missouri, United States, 63090 United States, New York Rochester Ophthalmology Group Rochester, New York, United States, 14618 Glaucoma Consultants of the Capital Region Slingerlands, New York, United States, 12159 United States, North Carolina Thomas K. Mundorf, M.D. Charlotte, North Carolina, United States, 28204 Charlotte Eye Ear Nose and Throat Charlotte, North Carolina, United States, 28210 United States, Oklahoma The Eye Institute Tulsa, Oklahoma, United States, 74104 United States, Pennsylvania Wills Eye Hospital Philadelphia, Pennsylvania, United States, 19107 United States, South Dakota Black Hills Regional Eye Institute Rapid City, South Dakota, United States, 57701 United States, Texas Cataract & Glaucoma Center El Paso, Texas, United States, 79902 United States, Utah Stacy R. Smith, M.D. Salt Lake City, Utah, United States, 84117 Less <<
NCT00804115 Exfoliation Syndrome ... More >> Glaucoma Ocular Hypertension Less << Not Applicable Unknown December 2008 United States, New York ... More >> New York Eye and Ear Infirmary New York, New York, United States, 10003 Less <<
NCT00716859 - Completed - -
NCT00397241 Open-angle Glaucoma Phase 4 Completed - Greece ... More >> Glaucoma Unit, A University Dept of Ophthalmology Thessaloniki, Greece, 546 43 Less <<
NCT01243567 - Completed - -
NCT00872651 Open-angle Glaucoma ... More >> Ocular Hypertension Less << Phase 3 Completed - China, Guangdong ... More >> Zhongshan Ophthalmic Center, Sun Yat-sen University Guangzhou, Guangdong, China, 510060 Less <<
NCT01243567 Glaucoma, Open-Angle Phase 4 Completed - Portugal ... More >> Coimbra, Portugal Spain Madrid, Spain Less <<
NCT00716859 Glaucoma Phase 3 Completed - -
NCT00441883 Primary Open Angle Glaucoma ... More >> Ocular Hypertension Pigmentary Glaucoma Pseudoexfoliative Glaucoma Less << Phase 2 Completed - United States, California ... More >> Pfizer Investigational Site Artesia, California, United States, 90701 Pfizer Investigational Site Newport Beach, California, United States, 92663 Pfizer Investigational Site Petaluma, California, United States, 94954 Pfizer Investigational Site Poway, California, United States, 92064 United States, Connecticut Pfizer Investigational Site Danbury, Connecticut, United States, 06810-4004 United States, Florida Pfizer Investigational Site Jacksonville, Florida, United States, 32204 Pfizer Investigational Site Ormond Beach, Florida, United States, 32174 United States, Georgia Pfizer Investigational Site Atlanta, Georgia, United States, 30339 Pfizer Investigational Site Atlanta, Georgia, United States, 30342 United States, Indiana Pfizer Investigational Site Evansville, Indiana, United States, 47710 United States, Kentucky Pfizer Investigational Site Louisville, Kentucky, United States, 40217 United States, New York Pfizer Investigational Site Rochester, New York, United States, 14618 United States, North Carolina Pfizer Investigational Site Charlotte, North Carolina, United States, 28210 Pfizer Investigational Site High Point, North Carolina, United States, 27262 United States, Oklahoma Pfizer Investigational Site Tulsa, Oklahoma, United States, 74104 United States, Pennsylvania Pfizer Investigational Site Cranberry Township, Pennsylvania, United States, 16066 Pfizer Investigational Site Pittsburgh, Pennsylvania, United States, 15238 United States, Tennessee Pfizer Investigational Site Memphis, Tennessee, United States, 38119 United States, Texas Pfizer Investigational Site Austin, Texas, United States, 78705 Less <<
NCT03318146 Glaucoma Ocul... More >>ar Hypertension IOP Less << Not Applicable Not yet recruiting September 1, 2019 Israel ... More >> Shaare Zedek Medical Center Not yet recruiting Jerusalem, Israel, 9103102 Contact: Lilach Drori Wagschal, MD    972-2-9934193    lilach_111@walla.co.il    Contact: Orit Cohen, Mrs.    972-2-5645363    oritc@szmc.org.il Less <<
NCT00567788 Glaucoma, Angle-Closure Not Applicable Unknown July 2008 Singapore ... More >> Singapore National Eye Centre Singapore, Singapore, 168751 Less <<
NCT00845299 Glaucoma Ocul... More >>ar Hypertension Less << Phase 2 Completed - United States, California ... More >> Menlo Park, California, United States, 94025 Less <<
NCT00347841 Glaucoma Phase 4 Completed - United States, Pennsylvania ... More >> Dr. Noecker Pittsburgh, Pennsylvania, United States, 15213 Less <<
NCT00820300 Glaucoma Ocul... More >>ar Hypertension Less << Phase 2 Completed - United States, California ... More >> Menlo Park, California, United States, 94025 Less <<
NCT00541242 Ocular Hypertension ... More >> Glaucoma Less << Phase 4 Completed - United States, California ... More >> Newport Beach, California, United States Less <<
NCT01265719 - Completed - -
NCT00541242 - Completed - -
NCT01151904 Glaucoma, Angle-Closure Phase 4 Terminated(Difficulty with pat... More >>ient recruitment) Less << - Thailand ... More >> Bangkok, Thailand Less <<
NCT01151904 - Terminated(Difficulty with pat... More >>ient recruitment) Less << - -
NCT00706927 Retina Ocular... More >> Physiology Less << Not Applicable Completed - Austria ... More >> Department of Clinical Pharmacology Vienna, Austria, 1090 Less <<
NCT01042665 - Completed - United States, Florida ... More >> University of Miami Bascom Palmer Eye Institute Palm Beach Gardens, Florida, United States, 33418 Less <<
NCT01481077 Glaucoma Ocul... More >>ar Hypertension (OH) Less << Phase 2 Completed - United States, Arkansas ... More >> Vold Vision Springdale, Arkansas, United States, 72762 United States, Colorado Glaucoma Consultants of Colorado, PC Denver, Colorado, United States, 80134 United States, Connecticut Danbury Eye Physicians & Surgeons Danbury, Connecticut, United States, 06810 United States, Missouri Ophthalmology Consultants Inc. Des Peres, Missouri, United States, 63131 Ophthalmology Associates St. Louis, Missouri, United States, 63131 Comprehensive Eye Care, Ltd Washington, Missouri, United States, 63090 United States, Nevada Las Vegas Physicians Research Group Henderson, Nevada, United States, 89052 Abrams Eye Institute Las Vegas, Nevada, United States, 89148 United States, Pennsylvania Philadelphia Eye Associates Philadelphia, Pennsylvania, United States, 19148 United States, Tennessee University Eye Surgeons Maryville, Tennessee, United States, 37803 Total Eye Care, P.A. Memphis, Tennessee, United States, 38119 Less <<
NCT00941525 Open Angle Glaucoma|Ocular Hyp... More >>ertension Less << PHASE4 COMPLETED 2025-07-14 A' Department of Ophthalmology... More >>, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, 54636, Greece Less <<
NCT00751127 Glaucoma Open... More >> Angle Glaucoma Ocular Hypertension Less << Phase 3 Completed - United States, California ... More >> Pfizer Investigational Site La Jolla, California, United States, 92093-0946 Pfizer Investigational Site Los Angeles, California, United States, 90033 United States, Florida Pfizer Investigational Site Gainesville, Florida, United States, 32610 United States, Illinois Pfizer Investigational Site Chicago, Illinois, United States, 60611 Pfizer Investigational Site Chicago, Illinois, United States, 60612 United States, Kentucky Pfizer Investigational Site Louisville, Kentucky, United States, 40292 United States, Maryland Pfizer Investigational Site Baltimore, Maryland, United States, 21209 United States, Michigan Pfizer Investigational Site Ann Arbor, Michigan, United States United States, Missouri Pfizer Investigational Site St. Louis, Missouri, United States, 63110 United States, Nebraska Pfizer Investigational Site Omaha, Nebraska, United States, 68105 United States, New Jersey Pfizer Investigational Site River Edge, New Jersey, United States, 07661-1931 United States, New York Pfizer Investigational Site New York, New York, United States, 10003 Pfizer Investigational Site New York, New York, United States, 10029 United States, Oregon Pfizer Investigational Site Portland, Oregon, United States, 97210-3049 United States, Pennsylvania Pfizer Investigational Site Philadelphia, Pennsylvania, United States, 19107-5599 United States, South Carolina Pfizer Investigational Site Charleston, South Carolina, United States, 29425-0001 United States, Wisconsin Pfizer Investigational Site Madison, Wisconsin, United States, 53705-3611 Less <<
NCT01265719 - Completed - -
NCT01917383 Primary Open-Angle Glaucoma (P... More >>OAG) Ocular Hypertension (OHT) Less << Phase 2 Completed - United States, Tennessee ... More >> Chiltern Bristol, Tennessee, United States, 37620 Less <<
NCT00800267 Ocular Hypertension ... More >> Glaucoma Less << Phase 3 Completed - -
NCT00219596 Glaucoma, Open Angle ... More >> Ocular Hypertension Less << Phase 3 Completed - China, Beijing ... More >> Pfizer Investigational Site Beijing, Beijing, China, 100034 Pfizer Investigational Site Beijing, Beijing, China, 100730 China, Guangdong Pfizer Investigational Site Guangzhou, Guangdong, China, 510060 China, Shanghai Pfizer Investigational Site Shanghai, Shanghai, China, 200092 China, Shanxi Pfizer Investigational Site Xi?an, Shanxi, China, 710004 China, Zhejiang Pfizer Investigational Site Hangzhou, Zhejiang, China, 310003 Pfizer Investigational Site Hangzhou, Zhejiang, China, 310009 China Pfizer Investigational Site Shanghai, China, 200031 Less <<
NCT01229982 Ocular Hypertension ... More >> Open Angle Glaucoma Less << Phase 2 Completed - Canada, British Columbia ... More >> QLT Inc. Vancouver, British Columbia, Canada, V5T 4T5 Less <<
NCT02047630 Primary Open Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 4 Terminated(Problem with IP sup... More >>ply) Less << - Canada ... More >> Centre universitaire d'ophtalmologie, Hôpital du Saint-Sacrement, CHU de Québec Québec, Canada, G1S 4L8 Less <<
NCT01481051 Glaucoma Ocul... More >>ar Hypertension (OH) Less << Phase 2 Completed - United States, California ... More >> Sall Research Medical Center, Inc Artesia, California, United States, 90701 Wolstan & Goldberg Eye Associates Los Angeles, California, United States, 90505 West Coast Eye Care Associates San Diego, California, United States, 92115 United States, Georgia Coastal Research Associates, LLC Roswell, Georgia, United States, 30076 United States, Texas R and R Eye Associates San Antonio, Texas, United States, 78229 United States, Utah Rocky Mountain Eye Care Associates Salt Lake City, Utah, United States, 84107 Less <<
NCT00847483 Glaucoma Ocul... More >>ar Hypertension Less << Phase 4 Completed - -
NCT01379144 Primary Open Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 2 Completed - Australia, New South Wales ... More >> Eye Associates Pty Limited Sydney, New South Wales, Australia, 2000 Save Sight Institute Sydney, New South Wales, Australia, 2000 Australia, South Australia Royal Adelaide Hospital, North Terrace Adelaide, South Australia, Australia, 5000 Czechia University Hospital Brno-Bohunice Brno, Czechia, CZ - 62500 Private Ophthalmology, V Hurkach 1296 Prague 5, Czechia, 150 00 Institute of Aviation Medicine, Generalal Piky 1 Prague 9, Czechia, 160 60 Specializovana Glaukomova Poradna, Blanicka 25 Praha 2, Czechia, 120 00 VseobecnBfakultnf nemocnice Praha 2, Czechia, 128 21 France Hopital De La Timone Marseille, France Hopital Des Armees Laveran Marseille, France Fondation Adolphe De Rothchild Paris, France, 75016 Hopital Civil Strasbourg, France Greece Akadimos Ophthalmology Center of Northern Greece Thessaloniki, Greece Pakistan Layton Rahmatullah Benevolent Trust (LRBT), Eye Hospital Lahore, Punjab, Pakistan Services Hospital Lahore Lahore, Punjab, Pakistan Aga Khan University Hospital Karachi Karachi, Sindh, Pakistan Civil Hospital Karachi Karachi, Sindh, Pakistan Portugal A.I.B.I.L.I. Coimbra, Portugal, 3000 Hospital De S. Jose Lisboa, Portugal Hospital Pedro Hispano Matosinhos, Portugal Thailand Siriraj Hospital, Ophthalmology Bangkok, Thailand, 10700 Chulalongkorn Hospital Bangkok, Thailand United Kingdom Birmingham Heartlands Hospital Birmingham, United Kingdom, B9 5SS Glasgow Royal Infirmary Glasgow, United Kingdom, G4 0SF Sunderland Eye Infirmary Sunderland, United Kingdom, SR2 9HP Less <<
NCT02129673 Open Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 1 Phase 2 Completed - United States, Washington ... More >> Speciality Eyecare Centre Bellevue, Washington, United States Less <<
NCT01987323 Ocular Hypertension Phase 1 Phase 2 Completed - -
NCT01223378 - Completed - -
NCT02829996 Primary Open-Angle Glaucoma (P... More >>OAG) Ocular Hypertension (OHT) Less << Phase 2 Completed - United States, Massachusetts ... More >> Inotek Pharmaceuticals Corporation Lexington, Massachusetts, United States, 02421 Less <<
NCT01223378 Intraocular Pressure Phase 2 Completed - United States, New York ... More >> Bausch & Lomb, Inc Rochester, New York, United States, 14609 Less <<
NCT02829996 - Completed - -
NCT00647101 Glaucoma, Open-Angle|Ocular Hy... More >>pertension Less << PHASE4 COMPLETED 2025-02-05 Pfizer Investigational Site, A... More >>lbi, 81000, France|Pfizer Investigational Site, Ambert, 63600, France|Pfizer Investigational Site, Amboise, 37400, France|Pfizer Investigational Site, Angers, 49100, France|Pfizer Investigational Site, Antibes, 06600, France|Pfizer Investigational Site, Aubenas, 07200, France|Pfizer Investigational Site, Belfort, 90000, France|Pfizer Investigational Site, Bergerac, 24100, France|Pfizer Investigational Site, Bernay, 27300, France|Pfizer Investigational Site, Bethune, 62400, France|Pfizer Investigational Site, Beziers, 34500, France|Pfizer Investigational Site, Blagnac, 31700, France|Pfizer Investigational Site, Bordeaux, 33000, France|Pfizer Investigational Site, Bordeaux, 33100, France|Pfizer Investigational Site, Bougival, 78380, France|Pfizer Investigational Site, Boulogne-Billancourt, 92100, France|Pfizer Investigational Site, Brest, 29200, France|Pfizer Investigational Site, Bry Sur Marne, 94360, France|Pfizer Investigational Site, Carentan, 50500, France|Pfizer Investigational Site, Cenon, 33150, France|Pfizer Investigational Site, Chamalieres, 63400, France|Pfizer Investigational Site, Chantilly, 60500, France|Pfizer Investigational Site, Chartres, 28000, France|Pfizer Investigational Site, Chateaubriant, 44110, France|Pfizer Investigational Site, Chateaulin, 29150, France|Pfizer Investigational Site, Clermont-Ferrand, 63100, France|Pfizer Investigational Site, Condom, 32100, France|Pfizer Investigational Site, Coulommiers, 77120, France|Pfizer Investigational Site, Courbevoie, 92400, France|Pfizer Investigational Site, Creil, 60100, France|Pfizer Investigational Site, Deauville, 14800, France|Pfizer Investigational Site, Deuil la Barre, 95170, France|Pfizer Investigational Site, Douai, 59500, France|Pfizer Investigational Site, Draveil, 91210, France|Pfizer Investigational Site, Enghien Les Bains, 95880, France|Pfizer Investigational Site, Epernay, 51200, France|Pfizer Investigational Site, Fontaine, 38600, France|Pfizer Investigational Site, Frejus, 83600, France|Pfizer Investigational Site, Gennevilliers, 92230, France|Pfizer Investigational Site, Gradignan, 33170, France|Pfizer Investigational Site, Grasse, 06130, France|Pfizer Investigational Site, Grasse, 06135, France|Pfizer Investigational Site, Grenoble, 38000, France|Pfizer Investigational Site, Grenoble, 38100, France|Pfizer Investigational Site, Guingamp, 22200, France|Pfizer Investigational Site, Haguenau, 67500, France|Pfizer Investigational Site, Herblay, 95220, France|Pfizer Investigational Site, Hyeres, 83400, France|Pfizer Investigational Site, Issy Les Moulineaux, 92130, France|Pfizer Investigational Site, Ivry Sur Seine, 94210, France|Pfizer Investigational Site, Jarville La Malgrange, 5414, France|Pfizer Investigational Site, Joigny, 89300, France|Pfizer Investigational Site, Juvisy Sur Orge, 91260, France|Pfizer Investigational Site, La Rochelle, 17000, France|Pfizer Investigational Site, La Talaudiere, 42350, France|Pfizer Investigational Site, La Trinite, 06340, France|Pfizer Investigational Site, Landerneau, 29800, France|Pfizer Investigational Site, Langon, 33210, France|Pfizer Investigational Site, Lannion, 22300, France|Pfizer Investigational Site, Laon, 02000, France|Pfizer Investigational Site, Le Creuzot, 71200, France|Pfizer Investigational Site, Le Havre, 76600, France|Pfizer Investigational Site, Le Mans, 72000, France|Pfizer Investigational Site, Le Peage De Rousillon, 38550, France|Pfizer Investigational Site, Le Quesnoy, 59530, France|Pfizer Investigational Site, Lesneven, 29260, France|Pfizer Investigational Site, Lille, 59000, France|Pfizer Investigational Site, Livry Gargan, 93190, France|Pfizer Investigational Site, Lunel, 34400, France|Pfizer Investigational Site, Luneville, 54300, France|Pfizer Investigational Site, Luxeuil les Bains, 70300, France|Pfizer Investigational Site, Lyon, 69002, France|Pfizer Investigational Site, Lyon, 69006, France|Pfizer Investigational Site, Lyon, 69008, France|Pfizer Investigational Site, Lyon, 69437, France|Pfizer Investigational Site, Maisons Laffitte, 78600, France|Pfizer Investigational Site, Marcq en Baroeul, 59700, France|Pfizer Investigational Site, Marignanne, 13700, France|Pfizer Investigational Site, Marseille, 13001, France|Pfizer Investigational Site, Marseille, 13004, France|Pfizer Investigational Site, Marseille, 13008, France|Pfizer Investigational Site, MArseille, 13009, France|Pfizer Investigational Site, Marseille, 13012, France|Pfizer Investigational Site, Meyzieu, 69330, France|Pfizer Investigational Site, Montauban, 82000, France|Pfizer Investigational Site, Montceau Les Mines, 71300, France|Pfizer Investigational Site, Montpellier, 34000, France|Pfizer Investigational Site, Mulhouse, 68200, France|Pfizer Investigational Site, Nantes, 44000, France|Pfizer Investigational Site, Nice, 06000, France|Pfizer Investigational Site, Nice, 06300, France|Pfizer Investigational Site, Nimes Cedex 2, 30918, France|Pfizer Investigational Site, Nimes, 30000, France|Pfizer Investigational Site, Niort, 79000, France|Pfizer Investigational Site, Nogent Sur Marne, 94130, France|Pfizer Investigational Site, Noyon, 60400, France|Pfizer Investigational Site, Orleans, 45000, France|Pfizer Investigational Site, Oullins, 69600, France|Pfizer Investigational Site, Pantin, 93500, France|Pfizer Investigational Site, Paray le Monial, 71600, France|Pfizer Investigational Site, Paris, 75006, France|Pfizer Investigational Site, Paris, 75008, France|Pfizer Investigational Site, Paris, 75009, France|Pfizer Investigational Site, Paris, 75010, France|Pfizer Investigational Site, Paris, 75012, France|Pfizer Investigational Site, Paris, 75013, France|Pfizer Investigational Site, Paris, 75014, France|Pfizer Investigational Site, Paris, 75015, France|Pfizer Investigational Site, Paris, 75016, France|Pfizer Investigational Site, Paris, 75018, France|Pfizer Investigational Site, Paris, 75019, France|Pfizer Investigational Site, Paris, 75020, France|Pfizer Investigational Site, Paris, 75116, France|Pfizer Investigational Site, Pauillac, 33250, France|Pfizer Investigational Site, Pau, 64000, France|Pfizer Investigational Site, Perigueux, 24000, France|Pfizer Investigational Site, Perros Girec, 22700, France|Pfizer Investigational Site, Pezenas, 34120, France|Pfizer Investigational Site, Poissy, 78300, France|Pfizer Investigational Site, Poitiers, 86000, France|Pfizer Investigational Site, Pont de Cheruy, 38230, France|Pfizer Investigational Site, Pornic, 44210, France|Pfizer Investigational Site, Port De Bouc, 13110, France|Pfizer Investigational Site, Quimper, 29000, France|Pfizer Investigational Site, Reims, 51100, France|Pfizer Investigational Site, Rochefort, 17300, France|Pfizer Investigational Site, Romilly sur Seine, 10100, France|Pfizer Investigational Site, Saint Die des Vosges, 88100, France|Pfizer Investigational Site, Saint Etienne, 42000, France|Pfizer Investigational Site, Saint Gaudens, 31800, France|Pfizer Investigational Site, Saint Savine, 10300, France|Pfizer Investigational Site, Saintes, 17100, France|Pfizer Investigational Site, Salon de Provence, 13300, France|Pfizer Investigational Site, Sartrouville, 78500, France|Pfizer Investigational Site, Sens, 89100, France|Pfizer Investigational Site, Sessiney Pariset, 38170, France|Pfizer Investigational Site, Sete, 34200, France|Pfizer Investigational Site, Soissons, 02209, France|Pfizer Investigational Site, St Chamond, 42200, France|Pfizer Investigational Site, St Etienne, 42100, France|Pfizer Investigational Site, St Michel Sur Orge, 91240, France|Pfizer Investigational Site, St. Brieuc, 22015, France|Pfizer Investigational Site, St. Lo, 50000, France|Pfizer Investigational Site, Strasbourg, 67000, France|Pfizer Investigational Site, Strasbourg, 67200, France|Pfizer Investigational Site, Suresnes, 92150, France|Pfizer Investigational Site, Talence, 33400, France|Pfizer Investigational Site, Thiers, 63300, France|Pfizer Investigational Site, Toulon, 83000, France|Pfizer Investigational Site, Toulouse, 31500, France|Pfizer Investigational Site, Toulouse, 34100, France|Pfizer Investigational Site, Tourcoing, 59200, France|Pfizer Investigational Site, Tournefeuille, 31170, France|Pfizer Investigational Site, Tours, 37000, France|Pfizer Investigational Site, Trelissac, 24750, France|Pfizer Investigational Site, Tremblay en France, 93290, France|Pfizer Investigational Site, Triel Sur Seine, 78510, France|Pfizer Investigational Site, Troyes, 10000, France|Pfizer Investigational Site, Valenciennes, 59300, France|Pfizer Investigational Site, Vannes, 56000, France|Pfizer Investigational Site, Vauvert, 30600, France|Pfizer Investigational Site, Veauche, 42340, France|Pfizer Investigational Site, Velaux, 13800, France|Pfizer Investigational Site, Vendargues, 34740, France|Pfizer Investigational Site, Venissieux Cedex, 69694, France|Pfizer Investigational Site, Viarmes, 95270, France|Pfizer Investigational Site, Vienne, 38200, France|Pfizer Investigational Site, Villeneuve D'Ascq, 59650, France|Pfizer Investigational Site, Villeneuve la Garenne, 92390, France|Pfizer Investigational Site, Villeneuve Saint Georges, 94190, France|Pfizer Investigational Site, Villeparisis, 77270, France|Pfizer Investigational Site, Villepinte, 93420, France|Pfizer Investigational Site, Villiers Le Bel, 95400, France|Pfizer Investigational Site, Vizille, 38220, France|Pfizer Investigational Site, Voiron, 38500, France|Pfizer Investigational Site, Wattrelos, 59150, France Less <<
NCT02154217 Glaucoma Phase 3 Completed - Germany ... More >> Universitaets-augenklinik Dresden, Germany Universitaets-augenklinik Magdeburg, Germany Greece Department of Ophthalmology, University of Thessaly, University Hos- pital of Larissa Larissa, Greece II Department of Ophthalmology, Aristotle University of Thessaloniki Thessaloniki, Greece Italy A.O. San Paolo Milan, Lombardy, Italy, 20142 Clinica Oculistica, Dipartimento di Oftalmologia-Otorinolaringoiatria, Università di Bari Bari, Italy Clinica Oculistica, Università degli studi di Roma, Tor Vergata Rome, Italy Switzerland Universitäts-Augenklinik, Inselspital, University of Bern Bern, Switzerland United Kingdom Moorfields Eye Hospital, London, United Kingdom Less <<
NCT02531152 Open Angle Glaucoma -Ocular Hy... More >>pertension Less << Phase 1 Completed - United States, California ... More >> Investigational Site Number 840001 Inglewood, California, United States, 90301 United States, Florida Investigational Site Number 840003 Cape Coral, Florida, United States, 33904 United States, Georgia Investigational Site Number 840005 Roswell, Georgia, United States, 30076 United States, Michigan Investigational Site Number 840004 St Joseph, Michigan, United States, 49085 United States, Tennessee Investigational Site Number 840002 Memphis, Tennessee, United States, 38119 Less <<
NCT01973114 Menière's Disease Phase 2 Unknown - Sweden ... More >> Falu Lasarett Falun, Sweden Sahlgrenska Universitetssjukhuset Göteborg, Sweden Blekinge Hospital Karlskrona, Sweden Centralsjukhuset i Karlstad Karlstad, Sweden Centralsjukhuset i Kristianstad Kristianstad, Sweden Linköping University Hospital Linköping, Sweden Sunderby Sjukhus Luleå, Sweden Lund University Hospital Lund, Sweden Karolinska Universitetssjukhuset Stockholm, Sweden Uppsala University Hospital Uppsala, Sweden Västmanlands Sjukhus i Västerås Västerås, Sweden University Hospital Örebro Örebro, Sweden Less <<
NCT00855517 Glaucoma Ocul... More >>ar Hypertension Less << Phase 2 Withdrawn(Sponsor's decision) July 2009 -
NCT02585375 Glaucoma Ocul... More >>ar Hypertension Less << Phase 4 Recruiting December 2018 Austria ... More >> Department of Clinical Pharmacology, Medical University of Vienna Recruiting Vienna, Austria, 1090 Contact: Gerhard Garhofer, MD    00431 40400 ext 29810    gerhard.garhoefer@meduniwien.ac.at Less <<
NCT01426464 Glaucoma Phase 2 Unknown December 2011 United States, California ... More >> Eye Surgical and Medical Associates Not yet recruiting Visalia, California, United States, 93277 Contact: Michael Boone, MD    559-627-9393    drboone@visaliaeyecare.com    Contact: Amy Smith    559-627-9393    amys@visaliaeyecare.com    Sub-Investigator: Michael Boone, MD Less <<
NCT01779284 Glaucoma Phase 4 Completed - Greece ... More >> Glaucoma Unit, 1st University Department of Ophthalmology Thessaloniki, Greece, 546 36 Less <<
NCT02138461 - Completed - United States, California ... More >> Harvard Eye Associates Laguna Hills, California, United States, 92653 Less <<
NCT01731002 - Completed - -
NCT02138461 - Completed - -
NCT01731002 Ocular Hypertension ... More >> Open Angle Glaucoma Less << Phase 2 Completed - United States, California ... More >> Kenneth Sall, M.D. Artesia, California, United States, 90701 United Medical Research Institute Inglewood, California, United States, 90301 Aesthetic Eye Care Institute Newport Beach, California, United States, 92657 North Bay Eye Associates Petaluma, California, United States, 94954 Centre For Health Care Poway, California, United States, 92064 United States, Georgia Clayton Eye Center Morrow, Georgia, United States, 30260 Coastal Research Associates, LLC Roswell, Georgia, United States, 30076 United States, Kansas Bradley Kwapiszeski, MD Shawnee Mission, Kansas, United States, 66204 United States, Kentucky Taustine Eye Center Louisville, Kentucky, United States, 40217 United States, Maryland Alan L Robin, M.D. Baltimore, Maryland, United States, 21209 Seidenberg Protzko Eye Associates Havre De Grace, Maryland, United States, 21078 United States, Michigan Great Lakes Eye Care Saint Joseph, Michigan, United States, 49085 United States, New York Ophthalmic Consultants of Long Island Lynbrook, New York, United States, 11563 Rochester Ophthalmological Group Rochester, New York, United States, 14618 United States, North Carolina Charlotte Eye Ear Nose and Throat Charlotte, North Carolina, United States, 28210 Michael E. Tepedino, M.D. High Point, North Carolina, United States, 27262 United States, Oklahoma The Eye Institute Tulsa, Oklahoma, United States, 74104 United States, Pennsylvania Wills Eye Hospital Philadelphia, Pennsylvania, United States, 19107 United States, Texas Texan Eye Austin, Texas, United States, 78731 Cataract & Glaucoma Center El Paso, Texas, United States, 79902 Medical Center Ophth. Associates San Antonio, Texas, United States, 78731 United States, Virginia Virginia Eye Consultants Norfolk, Virginia, United States, 23502 Less <<
NCT02981446 Open Angle Glaucoma or Ocular ... More >>Hypertension Less << Phase 3 Recruiting - Singapore ... More >> Recruiting Singapore, Singapore Contact: Santen Pharmaceutical Co., Ltd.    +81-6-6321-7394    clinical@santen.co.jp Less <<
NCT01527682 Childhood Glaucoma Phase 2 Unknown July 2017 Italy ... More >> Azienda Ospedaliera Spedali Civili di Brescia Brescia, Italy, 25123 A.O. Universitaria " Policlinico Vittorio Emanuele" P.O. Rodolico Catania, Italy, 95123 Less <<
NCT01361841 Ocular Hypertension ... More >> Primary Glaucoma Less << Not Applicable Unknown January 2013 Canada, Quebec ... More >> Centre hospitalier de Sherbrooke Recruiting Sherbrooke, Quebec, Canada, J1H 5N4 Contact: Pierre PB Blondeau, MD    1 (819) 346 1110 ext 28008    pierre.blondeau@videotron.ca Less <<
NCT00906594 Glaucoma Phase 4 Completed - Brazil ... More >> University of Sao Paulo Sao Paulo, SP, Brazil Less <<
NCT01975714 Glaucoma Ocul... More >>ar Hypertension Less << Phase 4 Completed - Austria ... More >> Vienna, Austria Belgium Leuven, Belgium Italy Milan, Italy Rome, Italy Portugal Coimbra, Portugal Switzerland Geneva, Switzerland United Kingdom London, United Kingdom Less <<
NCT02350023 Alopecia Areata Phase 4 Completed - India ... More >> Dept of Dermatology, PGIMER Chandigarh, India, 160012 Less <<
NCT02822742 Primary Open Angle Glaucoma or... More >> Ocular Hypertension Less << Phase 3 Completed - Japan ... More >> Tokyo, Japan Less <<
NCT01448837 Glaucoma Phase 4 Completed - Greece ... More >> Glaucoma Unit, 1st University Department of Ophthalmology Thessaloniki, Greece Less <<
NCT00579969 Glaucoma Phase 2 Terminated(Study stopped and d... More >>ata not analyzed) Less << - United States, Nebraska ... More >> UNMC Department of Ophthalmolgy and Visual Sciences Omaha, Nebraska, United States, 68198-5540 Less <<
NCT00757835 Glaucoma Phase 4 Completed - -
NCT02014142 Ocular Hypertension ... More >> Open-Angle Glaucoma Less << Phase 2 Completed - United States, Arizona ... More >> Arizona Eye Center Chandler, Arizona, United States, 85225 Arizona Glaucoma Specialists Phoenix, Arizona, United States, 85050 United States, California Wolstan & Goldberg Eye Associates Torrance, California, United States, 90505 United States, Florida Argus Research at Cape Coral Eye Center Cape Coral, Florida, United States, 33904 Eye Associates of Fort Myers Fort Myers, Florida, United States, 33901 United States, Indiana Indiana Universtiy - Eugene and Marilyn Glick Eye Institute Ophthalmology Center Indianapolis, Indiana, United States, 46202 United States, Kentucky Cincinnati Eye Institute Edgewood, Kentucky, United States, 41017 United States, Michigan Great Lakes Eye Care St. Joseph, Michigan, United States, 49085 United States, Minnesota Chu Vision Institute Bloomington, Minnesota, United States, 55420 United States, Missouri Ophthalmology Associates St. Louis, Missouri, United States, 63131 Comprehensive Eye Care, Ltd. Washington, Missouri, United States, 63090 United States, Nevada Abrams Eye Institute Las Vegas, Nevada, United States, 89148 United States, New York Ophthalmic Consultants of Long Island Lynbrook, New York, United States, 11563 Dr. Steven T. Simmons Slingerlands, New York, United States, 12159 United States, Pennsylvania Philadelphia Eye Associates Philadelphia, Pennsylvania, United States, 19148 Wills Eye Hospital Phildelphia, Pennsylvania, United States, 19107 United States, Tennessee University Eye Surgeons Maryville, Tennessee, United States, 37803 Total Eye Care Memphis, Tennessee, United States, 38119 Less <<
NCT00712400 Ocular Physiology ... More >> Intraocular Pressure Regional Blood Flow Less << Not Applicable Completed - Austria ... More >> Department of Clinical Pharmacology Vienna, Austria, 1090 Less <<
NCT02466399 Glaucoma Phase 2 Completed - United States, South Carolina ... More >> Professional Research Network Goose Creek, South Carolina, United States, 29445 Less <<
NCT00224289 Glaucoma Phase 4 Completed - United States, Connecticut ... More >> Yale Eye Center New Haven, Connecticut, United States, 06510 Less <<
NCT00856622 Ocular Hypertension ... More >> Glaucoma Open-angle Glaucoma Less << Phase 3 Completed - Germany ... More >> Pfizer Investigational Site Aachen, Germany Pfizer Investigational Site Aalen, Germany Pfizer Investigational Site Ahaus, Germany, 48683 Pfizer Investigational Site Alzey, Germany, 55232 Pfizer Investigational Site Aschaffenburg, Germany, 63739 Pfizer Investigational Site Bad Abbach, Germany, 93077 Pfizer Investigational Site Berlin, Germany, 13088 Pfizer Investigational Site Coesfeld, Germany, 48653 Pfizer Investigational Site Dillingen, Germany, 89407 Pfizer Investigational Site Eitorf, Germany, 53783 Pfizer Investigational Site Erlangen, Germany, 91052 Pfizer Investigational Site Essen, Germany, 45147 Pfizer Investigational Site Freiburg, Germany, 79106 Pfizer Investigational Site Freising, Germany, 85354 Pfizer Investigational Site Fulda, Germany Pfizer Investigational Site Greifswald, Germany, 17489 Pfizer Investigational Site Gummersbach, Germany, 51643 Pfizer Investigational Site Hannover, Germany Pfizer Investigational Site Hirschaid, Germany, 96114 Pfizer Investigational Site Iserlohn, Germany, 58638 Pfizer Investigational Site Koblenz, Germany, 56068 Pfizer Investigational Site Leonberg, Germany, 71229 Pfizer Investigational Site Leverkusen, Germany, 51373 Pfizer Investigational Site Mainz, Germany, 55116 Pfizer Investigational Site Mainz, Germany, 55124 Pfizer Investigational Site Mainz, Germany, 55131 Pfizer Investigational Site Muenchen, Germany, 80336 Pfizer Investigational Site Muenchen, Germany, 81925 Pfizer Investigational Site Mülheim, Germany, 45481 Pfizer Investigational Site Münster, Germany, 48165 Pfizer Investigational Site Offenbach, Germany, 63065 Pfizer Investigational Site Osnabrueck, Germany, 49076 Pfizer Investigational Site Parsberg, Germany, 92331 Pfizer Investigational Site Siegburg, Germany, 53721 Pfizer Investigational Site Sulzbach, Germany, 66280 Pfizer Investigational Site Trier, Germany, 54290 Pfizer Investigational Site Weiden, Germany, 92637 Less <<
NCT00187577 Alopecia Areata Not Applicable Completed - United States, California ... More >> University of California, San Francisco San Francisco, California, United States, 94117 Less <<
NCT01162603 Primary Open Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 4 Completed - Greece ... More >> Glaucoma Unit, 1st University Department of Ophthalmology, Aristotle University, AHEPA Hospital Thessaloniki, Greece, 54636 Italy USVD "Centro per lo studio del glaucoma" Spedali civili di Brescia Brescia, Italy, 25123 Less <<
NCT01896180 Primary Open Angle Glaucoma ... More >> Ocular Hypertension Elevated Intraocular Pressure Less << Phase 2 Completed - United States, Georgia ... More >> Morrow, Georgia, United States Less <<
NCT01225653 Diabetic Retinopathy PHASE4 COMPLETED 2025-12-14 Department of Ophthalmology, ?... More >>rhus University Hospital, ?rhus, 8000, Denmark Less <<
NCT00638742 Glaucoma Ocul... More >>ar Hypertension Less << Phase 1 Completed - United States, California ... More >> Pfizer Investigational Site Artesia, California, United States, 90701 United States, Georgia Pfizer Investigational Site Atlanta, Georgia, United States, 30339 Pfizer Investigational Site Atlanta, Georgia, United States, 30342 United States, Massachusetts Pfizer Investigational Site North Dartmouth, Massachusetts, United States, 02747 United States, Minnesota Pfizer Investigational Site Minneapolis, Minnesota, United States, 55455 United States, North Carolina Pfizer Investigational Site Durham, North Carolina, United States, 27705 Denmark Pfizer Investigational Site Koebenhavn OE, Denmark, 2100 Italy Pfizer Investigational Site Catania, Italy, 95123 Portugal Pfizer Investigational Site Coimbra, Portugal, 3000-548 Pfizer Investigational Site Lisboa, Portugal, 1169-097 South Africa Pfizer Investigational Site Mayfair West, South Africa, 2109 Spain Pfizer Investigational Site Madrid, Spain, 28040 Pfizer Investigational Site Madrid, Spain, 28046 Less <<
NCT00224289 - Completed - -
NCT01721707 Open Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 3 Withdrawn(withdrawn by industr... More >>y) Less << June 2013 Brazil ... More >> Department of Ophthalmology / Hospital São Paulo São Paulo, Brazil, 04023062 Less <<
NCT02792803 POAG Primary ... More >>Open Angle Glaucoma Ocular Hypertension Less << Phase 4 Recruiting September 2017 Canada, Ontario ... More >> Opthalmis Diagnostic Services Recruiting Toronto, Ontario, Canada, M5G1Z5 Contact: Jonathan Elin-Calcador    4165869626    jonathanec.ods@gmail.com    Principal Investigator: David B Yan, M.D., F.R.C.S. (C) Less <<
NCT03331770 Primary Open-angle Glaucoma Phase 4 Completed - Argentina ... More >> Laboratoarios Poen Buenos Aires, Argentina, 1407 Less <<
NCT03611348 Vitiligo Phase 2 Phase 3 Not yet recruiting December 1, 2019 -
NCT01430923 Glaucoma, Open-Angle ... More >> Ocular Hypertension Less << Not Applicable Unknown August 2012 India ... More >> Aravind Eye hospital Madurai, Tamilnadu, India, 625020 Less <<
NCT01180062 Primary Open Angle Glaucoma (P... More >>OAG) Ocular Hypertension (OHT) Less << Phase 1 Terminated(Study terminated ea... More >>rly due to manufacturer not replenishing study site supply of inserts, despite repeated requests for more inserts.) Less << - United States, Kentucky ... More >> Univ of Ky Dept of Ophthalmology and Visual Sciences Lexington, Kentucky, United States, 40546 Less <<
NCT03657797 Glaucoma, Open-Angle ... More >> Hypertension, Ocular Less << Phase 2 Recruiting December 2019 United States, Texas ... More >> Texan Eye Recruiting Austin, Texas, United States, 78731 Contact: Robert Stapper Less <<
NCT01580254 Intraocular Pressure (IOP) ... More >> Tear Break-Up Time Less << Phase 4 Unknown July 2012 Italy ... More >> University of Catanzaro - Eye Department Recruiting Catanzaro, Italy, 88100 Contact: Luigi Varano, M.D.    +3909613647365    luigi-varano@libero.it    Contact: Giovanni Scorcia, M. D.    +3909613647135    scorcia@unicz.it    Principal Investigator: Luigi Varano, M. D.          Sub-Investigator: Valentina De Luca Less <<
NCT00468988 Glaucoma Phase 4 Completed - United States, Florida ... More >> Orlando Orlando, Florida, United States, 32801 Less <<
NCT00798694 - Completed - -
NCT00465621 Open-Angle Glaucoma|Ocular Hyp... More >>ertension Less << PHASE2 COMPLETED - Atlanta, Atlanta, Georgia, 303... More >>42, United States Less <<
NCT01263444 Glaucoma Ocul... More >>ar Hypertension Less << Phase 4 Completed - -
NCT00798694 Glaucoma Phase 4 Completed - United States, Pennsylvania ... More >> Wills Eye Glaucoma Service Philadelphia, Pennsylvania, United States, 19107 Less <<
NCT01704989 Glaucoma Phase 4 Unknown December 2015 Canada, Nova Scotia ... More >> Eye Care Centre, VG Site, QEII Not yet recruiting Halifax, Nova Scotia, Canada, B3H 2Y9 Contact: Marcelo T Nicolela, MD    902-473-3622    nicolela@dal.ca    Principal Investigator: Marcelo T Nicolela, MD          Sub-Investigator: Lesya Shuba, MD          Sub-Investigator: Rizwan Malik, MD          Sub-Investigator: Paul Rafuse, MD          Sub-Investigator: Balwantray Chauhan, PhD Less <<
NCT00573638 Glaucoma Not Applicable Unknown December 2009 United States, Georgia ... More >> Medical College of Georgia Health Inc Recruiting Augusta, Georgia, United States, 30912 Less <<
NCT01895985 Intraocular Pressure Phase 1 Completed - United States, New Jersey ... More >> Bausch & Lomb Incorporated Madison, New Jersey, United States, 07940 Less <<
NCT01263444 - Completed - -
NCT00283764 Glaucoma, Open-Angle|Ocular Hy... More >>pertension Less << PHASE3 WITHDRAWN - -
NCT00143429 Glaucoma, Open-Angle|Ocular Hy... More >>pertension Less << PHASE2 WITHDRAWN - -
NCT00383019 Glaucoma, Primary Open Angle (... More >>POAG) Ocular Hypertension Less << Phase 3 Completed - -
NCT01155219 Glaucoma Phase 4 Completed - France ... More >> Clermont-Ferrand, France, 63000 Less <<
NCT01012245 - Completed - -
NCT00912054 Open Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 3 Terminated(poor enrollment) - Belgium ... More >> Cliniques Universitaires Saint Luc Brussels, Belgium Less <<
NCT01535768 Glaucoma Phase 4 Recruiting June 2020 Canada, Ontario ... More >> Credit Valley Eye Care Recruiting Mississauga, Ontario, Canada, L5L1W8 Contact: Amandeep S Rai, MD    647-987-4724    amandeeprai85@gmail.com    Principal Investigator: Devesh K Varma, MD FRCSC          Sub-Investigator: Ike K Ahmed, MD FRCSC Less <<
NCT01012245 - Completed - -
NCT00293787 Open-angle Glaucoma ... More >> Ocular Hypertension Less << Phase 3 Completed - -
NCT01155219 - Completed - -
NCT01125306 Glaucoma Hype... More >>rtension Less << Phase 4 Unknown October 2012 Israel ... More >> Ophthalmology department, Meir Medical Center Recruiting Kfar-Saba, Israel, 44281 Contact: Ronit Nesher, MD    972-9747555 ext 2774    nesher.ronit@clalit.org.il    Principal Investigator: Ronit Nesher, MD Less <<
NCT02419508 Open-Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 4 Completed - United States, Texas ... More >> Contact Alcon Call Center for Trial Locations Fort Worth, Texas, United States, 76134 Less <<
NCT00293800 Open-Angle Glaucoma ... More >> Ocular Hypertension Less << Phase 3 Completed - -
NCT00383019 - Completed - -
NCT02419508 - Completed - -
NCT02390284 Glaucoma Phase 3 Recruiting July 2019 United States, Florida ... More >> Bascom Palmer Eye Institute - University of Miami Recruiting Miami, Florida, United States, 33136 Contact: Marlene Perez, RC    305-482-4309    marlene.perez@med.miami.edu    Contact: Shiva Roghaee, RA    305 482 4309    sxr935@med.miami.edu    Principal Investigator: Vittorio Porciatti, DSc          Sub-Investigator: John J McSoley, OD          Sub-Investigator: Luis E Vazquez, MD,PhD          Sub-Investigator: Steven J Gedde, MD          Sub-Investigator: Pedro F Monsalve, RA          Sub-Investigator: Maja Kostic, PhD Less <<
NCT02656979 Glaucoma UNKNOWN 2025-09-19 Department of Clinical Science... More >>, Ophthalmology, Ume? University, Ume?, V?sterbotten, 90187, Sweden Less <<
NCT06239324 Alopecia Areata PHASE1|PHASE2 RECRUITING 2024-05-01 Qena Hospital, Qinā, Egypt

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.31mL

0.46mL

0.23mL

11.56mL

2.31mL

1.16mL

23.12mL

4.62mL

2.31mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

References

 

Historical Records

Categories