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Chemical Structure| 473921-12-9 Chemical Structure| 473921-12-9

Structure of Lersivirine
CAS No.: 473921-12-9

Chemical Structure| 473921-12-9

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Lersivirine is a next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI, IC50=119 nM) with a unique resistance profile that exhibits potent antiretroviral activity against wild-type human immunodeficiency virus and clinically relevant NNRTI-resistant strains.

Synonyms: UK-453061; UK-453,061

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Product Details of Lersivirine

CAS No. :473921-12-9
Formula : C17H18N4O2
M.W : 310.35
SMILES Code : CCC1=NN(CCO)C(CC)=C1OC2=CC(C#N)=CC(C#N)=C2
Synonyms :
UK-453061; UK-453,061
MDL No. :MFCD16619314
InChI Key :MCPUZZJBAHRIPO-UHFFFAOYSA-N
Pubchem ID :16739244

Safety of Lersivirine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Isoform Comparison

Biological Activity

Description
Lersivirine (UK-453061) is a potent and selective non-nucleoside reverse transcription inhibitor (NNRTI) with an IC50 of 119 nM, showing high efficacy against NNRTI-resistant viruses. It demonstrates strong antiretroviral effects against both wild-type HIV and clinically relevant NNRTI-resistant strains[1].

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Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.22mL

0.64mL

0.32mL

16.11mL

3.22mL

1.61mL

32.22mL

6.44mL

3.22mL

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