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Chemical Structure| 479-50-5 Chemical Structure| 479-50-5

Structure of Lucanthone
CAS No.: 479-50-5

Chemical Structure| 479-50-5

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Lucanthone, thioxanthone-based DNA intercalator, is an inhibitor of DNA repair enzyme apurinic-apyrimidinic endonuclease 1 (APEX1 or APE1).

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Product Details of Lucanthone

CAS No. :479-50-5
Formula : C20H24N2OS
M.W : 340.48
SMILES Code : O=C1C2=C(SC3=C1C=CC=C3)C(C)=CC=C2NCCN(CC)CC
MDL No. :MFCD00866726
InChI Key :FBQPGGIHOFZRGH-UHFFFAOYSA-N
Pubchem ID :10180

Safety of Lucanthone

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Lucanthone

DNA

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02014545 Brain Metastases ... More >> Non-small Cell Lung Cancer Less << Phase 2 Withdrawn(Pending resolution o... More >>f study drug issues) Less << - United States, North Carolina ... More >> Comprehensive Cancer Center of Wake Forest University Winston-Salem, North Carolina, United States, 27157 Less <<
NCT01587144 Glioblastoma Multiforme Phase 2 Terminated(Sponsor's decision) - United States, California ... More >> UCSD Moores Cancer Center La Jolla, California, United States, 92093 UCI Medical Center Orange, California, United States, 92868 United States, New York Dent Neurologic Institute Amherst, New York, United States, 14226 United States, Ohio Fairview Hospital Moll Cancer Center/Cleveland Clinic Cleveland, Ohio, United States, 44111 Cleveland Clinic Cleveland, Ohio, United States, 44195 Hillcrest Hospital Hirsh Cancer Center/Cleveland Clinic Mayfield, Ohio, United States, 44124 India Gujarat Cancer Research Institute Ahmedabad, Gujarat, India, 380016 Jaslok Hospital & Research Centre Mumbai, Maharashtra, India, 400062 Bhagwan Mahaveer Cancer Hospital & Reseach Centre Jaipur, Rajasthan, India, 302017 Chittaranjan National Cancer Institute Kolkata, West Bengal, India, 700026 Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.94mL

0.59mL

0.29mL

14.69mL

2.94mL

1.47mL

29.37mL

5.87mL

2.94mL

References

 

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