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Chemical Structure| 1599440-25-1 Chemical Structure| 1599440-25-1

Structure of 1599440-25-1

Chemical Structure| 1599440-25-1

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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a degradable ADC linker used for synthesizing antibody-drug conjugates (ADCs).

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Product Details of MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

CAS No. :1599440-25-1
Formula : C28H36N6O10
M.W : 616.62
SMILES Code : OC(COCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O
MDL No. :N/A
InChI Key :SODPQQOBNODMSG-FQEVSTJZSA-N
Pubchem ID :118305142

Safety of MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH serves as a cleavable ADC linker in the synthesis of antibody-drug conjugates (ADCs) [1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.62mL

0.32mL

0.16mL

8.11mL

1.62mL

0.81mL

16.22mL

3.24mL

1.62mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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