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Chemical Structure| 532-03-6 Chemical Structure| 532-03-6

Structure of Methocarbamol
CAS No.: 532-03-6

Chemical Structure| 532-03-6

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Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.

Synonyms: AHR 85; NSC 170960

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Product Details of Methocarbamol

CAS No. :532-03-6
Formula : C11H15NO5
M.W : 241.24
SMILES Code : OC(COC1=CC=CC=C1OC)COC(N)=O
Synonyms :
AHR 85; NSC 170960
MDL No. :MFCD00057662

Safety of Methocarbamol

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P280-P305+P351+P338-P310

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00770497 Inflammation ... More >>Hypertension Less << Phase 2 Completed - Germany ... More >> Deggingen, Baden-Württemberg, Germany Rottweil, Baden-Württemberg, Germany Spaichingen, Baden-Württemberg, Germany Weilersbach, Bayern, Germany Hannover, Niedersachsen, Germany Essen, Nordrhein-Westfalen, Germany Köln, Nordrhein-Westfalen, Germany Werne, Nordrhein-Westfalen, Germany Mainz, Rheinland-Pfalz, Germany Schauenburg, Rheinland-Pfalz, Germany Dresden, Sachsen, Germany Blankenhain, Thüringen, Germany Berlin, Germany Less <<
NCT02707094 Chronic Low Back Pain Not Applicable Completed - United States, Texas ... More >> Brooke Army Medical Center Fort Sam Houston, Texas, United States, 78234 Less <<
NCT02669875 Liver Cirrhosis ... More >> Hypertension, Portal Less << Phase 2 Completed - United Kingdom ... More >> Liver Unit, Royal Infirmary of Edinburgh Edinburgh, United Kingdom, EH164TJ Less <<
NCT01979614 Coronary Artery Disease Phase 2 Completed - United Kingdom ... More >> Novartis Investigative Site Clydebank, West Dumbartonshire, United Kingdom, G81 4HX Novartis Investigative Site Edinburgh, United Kingdom, EHN 2XU Novartis Investigative Site Leicester, United Kingdom, LE3 9QP Less <<
NCT00259103 Labor, Induced Phase 2 Completed - Russian Federation ... More >> Novosibirsk State Medical Academy Novosibirsk, Russian Federation Evidence CPR Saint Petersburg, Russian Federation, 199034 D.O. Ott Research Institute of Obstetrics and Gynecology Saint Petersburg, Russian Federation Less <<
NCT00770640 Diabetes Mellitus Phase 2 Completed - Germany ... More >> Schwetzingen, Baden-Württemberg, Germany Wiesbaden, Hessen, Germany Bottrop, Nordrhein-Westfalen, Germany Düsseldorf, Nordrhein-Westfalen, Germany Lüdenscheid, Nordrhein-Westfalen, Germany Solingen, Nordrhein-Westfalen, Germany Alzey, Rheinland-Pfalz, Germany Ingelheim, Rheinland-Pfalz, Germany Mainz, Rheinland-Pfalz, Germany Less <<
NCT02432456 Wounds and Injuries ... More >> Rib Fractures Less << Phase 4 Recruiting August 2018 United States, Wisconsin ... More >> Froedtert Memorial Lutheran Hospital Recruiting Milwaukee, Wisconsin, United States, 53226 Contact: Nathan W Kugler, MD    414-805-2955    nkugler@mcw.edu    Contact: Thomas W Carver, MD    414-805-8622    tcarver@mcw.edu Less <<
NCT00004380 Systemic Sclerosis Phase 2 Completed - -
NCT00704665 Systemic Sclerosis Phase 3 Completed - -
NCT02831569 - Completed - -
NCT01909492 - Recruiting September 2020 United States, Oregon ... More >> Providence MS Center Recruiting Portland, Oregon, United States, 97225 Contact: Tiffany Gervasi    503-216-1023    Tiffany.Gervasi@providence.org    Contact: Chiayi Chen, RN, PhD    (503) 216-1012    Chiayi.Chen@providence.org    Principal Investigator: Stanley Cohan, MD, PhD          Sub-Investigator: Kiren Kresa-Reahl, MD          Sub-Investigator: Roy Garvin, PhD          Sub-Investigator: Harry Reahl, MD          Sub-Investigator: Kyle Smoot, MD          Sub-Investigator: Elisabeth Lucassen, MD Less <<
NCT00406575 Congestive Heart Failure (CHF) Phase 2 Terminated - Russian Federation ... More >> Russian Scientific Centre of Surgery n.a. B.V.Petrovsky of Russian Academy of Medical Sciences Moscow, Russian Federation, 119992 Educational Scientific Medical Center of the General Management Department of the President of Russian Federation. City Clinical Hospital №51 Moscow, Russian Federation, 121309 Less <<
NCT01979510 Low Back Pain Phase 3 Withdrawn May 2014 -
NCT02831569 Pain Phase 3 Completed - Japan ... More >> Fukuwa Clinic Tokyo, Chuo-ku, Japan, 103-0027 Tokyo-Eki Center-building Clinic Tokyo, Chuo-ku, Japan, 103-0027 Shinjuku Res. Park Clinic, Tokyo, I.M. Tokyo, Shinjyuku-ku, Japan, 169-0073 Less <<
NCT00333307 Pre-Eclampsia Phase 1 Suspended - United States, Kentucky ... More >> Central Baptist Hospital Lexington, Kentucky, United States, 40503 United States, Ohio University of Cincinnati Cincinnati, Ohio, United States, 45267 Less <<
NCT00259116 Heart Failure, Congestive Phase 2 Completed - Germany ... More >> Charite Hospital Berlin, Germany, 10117 Less <<
NCT02665286 Low Back Pain Phase 4 Completed - United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less <<
NCT02665286 - Completed - -
NCT03449251 Cardiovascular Diseases ... More >> Type 2 Diabetes Mellitus Less << Phase 2 Recruiting February 2020 United Kingdom ... More >> Addenbrooke's Hospital Recruiting Cambridge, Cambridgeshire, United Kingdom, CB20QQ Contact: Joseph Cheriyan, MBChB, FRCP    01223 926590    jc403@medschl.cam.ac.uk    Principal Investigator: Joseph Cheriyan, MBChB, FRCP Less <<
NCT02642874 Liver Cirrhosis Phase 3 Recruiting December 2020 Egypt ... More >> Tanta university - faculty of medicine Recruiting Tanta, Elgharbia, Egypt Contact: Sherief Abdelsalam, lecturer    00201095159522    Sheriefabdelsalam@yahoo.com Less <<
NCT00520806 Heart Failure, Congestive Phase 2 Phase 3 Completed - United States, Illinois ... More >> Northwestern University Chicago, Illinois, United States, 60611 United States, Michigan Wayne State University/Detroit Receiving Hospital Detroit, Michigan, United States, 48201 Israel Heart Institute Safed, Israel Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.15mL

0.83mL

0.41mL

20.73mL

4.15mL

2.07mL

41.45mL

8.29mL

4.15mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

References

 

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