Home Cart Sign in  
Chemical Structure| 2241025-68-1 Chemical Structure| 2241025-68-1

Structure of MF-094
CAS No.: 2241025-68-1

Chemical Structure| 2241025-68-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

MF-094 is an effective, selective USP30 inhibitor with an IC50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitosis.

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of MF-094

CAS No. :2241025-68-1
Formula : C30H37N3O4S
M.W : 535.70
SMILES Code : O=C([C@H](CC1=CC=CC=C1)NC(C2CCCCC2)=O)NC3=CC=CC4=C3C=CC=C4S(=O)(NC(C)(C)C)=O
MDL No. :MFCD31813673

Safety of MF-094

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
neurons 180 nmol/L 24 hours Evaluate the effect of MF094 on neuronal survival rate, results showed maximum survival rate at 180 nmol/L Transl Stroke Res. 2025 Apr;16(2):448-466
HTR-8/SVneo trophoblast cells 120 nM 24 hours Increased FUNDC1 ubiquitination level, inhibited mitophagy and Δψm changes, reduced ROS and MDA, increased GSH and SOD, alleviated hypoxia-induced trophoblast cell injury Bioengineered. 2022 Feb;13(2):3620-3633
HOEC cells 0.2 to 2 μM 12, 24, 48 hours Evaluate the effect of MF-094 on cell viability, results showed that MF-094 significantly decreased the viability of HOEC cells Cell Mol Biol Lett. 2022 Dec 6;27(1):107
HSC4 cells 0.05 to 2 μM 12, 24, 48 hours Evaluate the effect of MF-094@NPs on cell viability, results showed that MF-094@NPs significantly decreased the viability of HSC4 cells Cell Mol Biol Lett. 2022 Dec 6;27(1):107

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Nude mice SCC4 cell subcutaneous injection-induced xenograft tumor model Tail vein injection 1 mg/kg/day Once daily for 4 weeks Evaluate the antitumor effect of MF-094@NPs, results showed that MF-094@NPs significantly inhibited tumor growth Cell Mol Biol Lett. 2022 Dec 6;27(1):107
C57BL/6 J mice Subarachnoid hemorrhage model Lateral ventricular injection 5 mg/kg Once daily until the end of the experiment Evaluate the improvement effect of MF094 on neurological injury and inflammatory response after SAH, results showed 5 mg/kg dose significantly improved neurological function Transl Stroke Res. 2025 Apr;16(2):448-466

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.87mL

0.37mL

0.19mL

9.33mL

1.87mL

0.93mL

18.67mL

3.73mL

1.87mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

Historical Records

Categories