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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 1933460-19-5 Chemical Structure| 1933460-19-5

Structure of Mitiperstat
CAS No.: 1933460-19-5

Chemical Structure| 1933460-19-5

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Mitiperstat is a potent myeloperoxidase (MPO) inhibitor primarily used for the prevention and treatment of cardiovascular diseases, such as heart failure and coronary artery disease. This compound reduces oxidative stress by inhibiting MPO activity, providing significant cardiovascular protection.

Synonyms: AZD4831

4.5 *For Research Use Only !

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Product Details of Mitiperstat

CAS No. :1933460-19-5
Formula : C15H15ClN4OS
M.W : 334.82
SMILES Code : O=C(NC1=S)C(NC=C2)=C2N1CC3=C(C=C(C=C3)Cl)[C@H](N)C
Synonyms :
AZD4831
MDL No. :N/A

Safety of Mitiperstat

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:3259
Packing Group:

Related Pathways of Mitiperstat

ferroptosis

Isoform Comparison

Biological Activity

Description
Mitiperstat (AZD4831) is a potent inhibitor of myeloperoxidase (MPO) and is particularly valuable in research aimed at the prophylaxis of cardiovascular disorders, including heart failure and coronary artery disease, as outlined in patent US20160152623A1[1].

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT05751759 Hepatic Impairment PHASE1 COMPLETED 2024-11-21 Research Site, Rialto, Califor... More >>nia, 92377, United States|Research Site, Hialeah, Florida, 33016, United States|Research Site, Orlando, Florida, 32808, United States|Research Site, Canton, Ohio, 44718, United States|Research Site, San Antonio, Texas, 78215, United States Less <<
NCT04949438 Renal Impairment PHASE1 COMPLETED 2022-03-04 Research Site, Sofia, 1612, Bu... More >>lgaria Less <<
NCT05457270 Healthy Volunteers PHASE1 COMPLETED 2022-10-17 Research Site, Brooklyn, Maryl... More >>and, 21225, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.99mL

0.60mL

0.30mL

14.93mL

2.99mL

1.49mL

29.87mL

5.97mL

2.99mL

References

 

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