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Chemical Structure| 1010085-13-8 Chemical Structure| 1010085-13-8

Structure of MK-5108
CAS No.: 1010085-13-8

Chemical Structure| 1010085-13-8

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MK-5108 is a potent and highly selective Aurora inhibitor with IC50 of 0.064, 14 and 12 nM for Aurora A, B and C.

Synonyms: VX-689

4.5 *For Research Use Only !

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Product Details of MK-5108

CAS No. :1010085-13-8
Formula : C22H21ClFN3O3S
M.W : 461.94
SMILES Code : FC(C(Cl)=CC=C1)=C1O[C@H](CC2)CC[C@@]2(C(O)=O)CC3=CC=CC(NC4=NC=CS4)=N3
Synonyms :
VX-689
MDL No. :MFCD22124479
InChI Key :LCVIRAZGMYMNNT-UHFFFAOYSA-N
Pubchem ID :24748204

Safety of MK-5108

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of MK-5108

epigenetics
DNA

Isoform Comparison

Biological Activity

Target
  • Aurora A

    Aurora A, IC50:0.064 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.16mL

0.43mL

0.22mL

10.82mL

2.16mL

1.08mL

21.65mL

4.33mL

2.16mL

References

 

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