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Chemical Structure| 1382722-47-5 Chemical Structure| 1382722-47-5

Structure of MMPI-1154
CAS No.: 1382722-47-5

Chemical Structure| 1382722-47-5

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MMPI-1154 is a novel cardioprotective agent and belongs to the imidazole-carboxylic acid MMP-2 inhibitors (IC50=6.6 μM). It can be used in acute myocardial infarction research and also inhibits MMP-13, MMP-1, and MMP-9, with IC50 values of 1.8 μM, 10 μM, and 13 μM, respectively, showing potential cardioprotective effects.

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Product Details of MMPI-1154

CAS No. :1382722-47-5
Formula : C26H24FN3O3
M.W : 445.49
SMILES Code : O=C(O)C1=CN=C(N1)CN(CC2=CC=C(F)C=C2)CC3=CC=C(OCC=4C=CC=CC4)C=C3
MDL No. :MFCD32693883

Safety of MMPI-1154

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.24mL

0.45mL

0.22mL

11.22mL

2.24mL

1.12mL

22.45mL

4.49mL

2.24mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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