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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 944252-63-5 Chemical Structure| 944252-63-5

Structure of Murepavadin
CAS No.: 944252-63-5

Chemical Structure| 944252-63-5

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Murepavadin is the first in class of the outer membrane protein-targeting antibiotics (OMPTA) and a pathogen-specific peptidomimetic antibacterial with a novel, nonlytic mechanism of action targeting Pseudomonas aeruginosa.

Synonyms: POL7080

4.5 *For Research Use Only !

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Product Details of Murepavadin

CAS No. :944252-63-5
Formula : C73H112N22O16
M.W : 1553.81
SMILES Code : O=C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCN)C(N[C@@H](CCN)C(N[C@@H](C)C(N[C@@H](CO)C(N1[C@@](CCC1)([H])C(N2[C@](CCC2)([H])C(N[C@]([C@H](O)C)([H])C3=O)=O)=O)=O)=O)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O)CCN)=O)CCN)=O)CCCN)=O)CCN)=O)([H])[C@@H](C)CC)[C@](N3)([H])CC6=CNC7=CC=CC=C67
Synonyms :
POL7080
MDL No. :N/A
InChI Key :RIDRXGOBXZLKHZ-NZUANIILSA-N
Pubchem ID :91824766

Safety of Murepavadin

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P280-P301+P310-P311
Class:6.1
UN#:2811
Packing Group:

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02110459 Renal Impairment PHASE1 COMPLETED 2025-07-15 CRS Clinical Research Services... More >> Kiel GmbH, Kiel, 24105, Germany Less <<
NCT02096328 Ventilator Associated Pneumoni... More >>a|Lower Respiratory Infection Less << PHASE2 COMPLETED 2025-12-16 ATTIKON University Hospital, A... More >>thens, Greece|Hospital EVANGELISMOS, Athens, Greece|Hospital KORGIALENIO-BENAKIO E.E.S, Athens, Greece|SOTIRA Pulmonary Clinic, Athens, Greece|Hospital Bellvitge, Barcelona, Spain|Hospital Clinic, Barcelona, Spain|Hospital Del Mar, Barcelona, Spain|Hospital Clinic San Carlos, Madrid, Spain|Hospital Joan XXIII, Tarragona, Spain|Hospital La Fe, Valencia, Spain Less <<
NCT02096315 Bronchiectasis|Lower Respirato... More >>ry Infection Less << PHASE2 TERMINATED 2025-11-15 Hospital Bellvitge, Barcelona,... More >> Spain|Hospital Clinic, Barcelona, Spain|Hospital La Fe, Valencia, Spain|Royal Infirmary, City of Edinburgh, United Kingdom Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

0.64mL

0.13mL

0.06mL

3.22mL

0.64mL

0.32mL

6.44mL

1.29mL

0.64mL

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