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Chemical Structure| 1628502-91-9 Chemical Structure| 1628502-91-9

Structure of MW-150
CAS No.: 1628502-91-9

Chemical Structure| 1628502-91-9

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MW-150 is a selective, orally active p38α MAPK inhibitor that penetrates the central nervous system, with a Ki value of 101 nM. This compound can inhibit the phosphorylation of the downstream substrate MK2 activated by p38α MAPK in glial cells, suitable for studies on neuroinflammation and neurodegenerative diseases.

Synonyms: MW01-18-150SRM

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Product Details of MW-150

CAS No. :1628502-91-9
Formula : C24H23N5
M.W : 381.47
SMILES Code : CN1CCN(C2=CC(C3=CC=NC=C3)=C(C4=CC5=C(C=CC=C5)C=C4)N=N2)CC1
Synonyms :
MW01-18-150SRM
MDL No. :MFCD32062790
InChI Key :CIIVUDIZZJLXCN-UHFFFAOYSA-N
Pubchem ID :86270361

Safety of MW-150

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Related Pathways of MW-150

MAPK
TLR

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.62mL

0.52mL

0.26mL

13.11mL

2.62mL

1.31mL

26.21mL

5.24mL

2.62mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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