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Chemical Structure| 849461-90-1 Chemical Structure| 849461-90-1

Structure of nAChR-IN-1
CAS No.: 849461-90-1

Chemical Structure| 849461-90-1

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nAChR-IN-1 is a selective nicotinic acetylcholine receptor inhibitor targeting receptors lacking α5, α6, or β3 subunits, with neuroprotective potential, suitable for research on neurological disorders and receptor dysfunction.

Synonyms: 2,2,6,6-tetramethylpiperidin-4-yl heptanoate

4.5 *For Research Use Only !

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Product Details of nAChR-IN-1

CAS No. :849461-90-1
Formula : C16H31NO2
M.W : 269.42
SMILES Code : CCCCCCC(OC1CC(C)(C)NC(C)(C)C1)=O
Synonyms :
2,2,6,6-tetramethylpiperidin-4-yl heptanoate

Safety of nAChR-IN-1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
nAChR-IN-1 (2,2,6,6-Tetramethylpiperidin-4-yl heptanoate) is a tetramethylpiperidine heptanoate, functioning as a selective nicotinic acetylcholine receptor (nAChR) inhibitor that targets nAChRs lacking α5, α6, or β3 subunits. It holds promise in preventing nerve disorders and can be applied in research on nicotinic acetylcholine receptor dysfunction or neurological disorders[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.71mL

0.74mL

0.37mL

18.56mL

3.71mL

1.86mL

37.12mL

7.42mL

3.71mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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