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| Type | HazMat fee for 500 gram (Estimated) |
| Excepted Quantity | USD 0.00 |
| Limited Quantity | USD 15-60 |
| Inaccessible (Haz class 6.1), Domestic | USD 80+ |
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Structure of Naproxen Sodium
CAS No.: 26159-34-2
*Storage: {[sel_prStorage]}
*Shipping: {[sel_prShipping]}
The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Naproxen is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.
Synonyms: RS-3650
4.5
*For Research Use Only !
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Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
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| CAS No. : | 26159-34-2 |
| Formula : | C14H13NaO3 |
| M.W : | 252.24 |
| SMILES Code : | O=C([C@H](C1=CC2=CC=C(OC)C=C2C=C1)C)[O-].[Na+] |
| Synonyms : |
RS-3650
|
| MDL No. : | MFCD00058507 |
| InChI Key : | CDBRNDSHEYLDJV-FVGYRXGTSA-M |
| Pubchem ID : | 23681059 |
| GHS Pictogram: |
|
| Signal Word: | Danger |
| Hazard Statements: | H302-H360 |
| Precautionary Statements: | P201-P280-P301+P312+P330-P308+P313 |
| Class: | 6.1 |
| UN#: | 2811 |
| Packing Group: | Ⅲ |
In Vitro:
| Concentration | Treated Time | Description | References |
| human Th17 cells | 1–10 μM | 48–72 h | Evaluate inhibition of IL-17 release; Naproxen showed no activity in this assay | Arthritis Res Ther. 2018 Mar 1;20(1):39. |
| human dendritic cells | 1–30 μM | 24 h | Evaluate inhibition of IL-23 release; Naproxen inhibited ~50% IL-23 release at 10 μM | Arthritis Res Ther. 2018 Mar 1;20(1):39. |
| CFSC-8B rat hepatic stellate cells | 0 to 10 μM | 16-18 h | To investigate the effect of Naproxen on VEGF and HGF expression, it was found that Naproxen significantly increased the expression of VEGF and HGF, especially under hypoxic conditions. | Gastroenterology. 2009 Jun;136(7):2356-64. |
| Tendon-derived stromal cells | 10 μM | 24 h | To investigate the effect of Naproxen on prostaglandin production induced by IL-1β, results showed that Naproxen significantly inhibited the production of 6-keto PGF1α and PGE2. | Arthritis Res Ther. 2019 Mar 13;21(1):74. |
In Vivo:
| Administration | Dosage | Frequency | Description | References |
| DBA/1 mice | Collagen-induced arthritis model | Oral | 60 mg/kg | Once daily for 10 days | Assess effects on arthritis clinical score and edema; Naproxen was ineffective in this model | Arthritis Res Ther. 2018 Mar 1;20(1):39. |
| Mice | Kras G12V mutant mice | Diet | 400 ppm | 30 weeks | To investigate the effects of Naproxen on spontaneous lung adenocarcinoma formation in Kras G12V mice. Results showed that Naproxen significantly inhibited lung tumor formation and reduced the incidence of adenocarcinoma. | Neoplasia. 2021 Jun;23(6):574-583 |
| Male Wistar rats | Wistar rats | Oral | 38.91 mg/kg and 65.78 mg/kg | Once daily for 14 days | To investigate the effects of Naproxen on oxidative stress, hepatotoxicity, and genotoxicity in male Wistar rats. Results showed that NP treatment decreased GSH levels and increased SOD, CAT, LPO, ALT, AST, ALP, and TBIL activities/levels. MNT results showed increased micronucleus induction, and the comet assay showed a significant increase in DNA damage. | J Pharm Anal. 2018 Dec;8(6):400-406 |
| Female Lewis rats | Collagen-induced arthritis (CIA) model | Oral gavage | 8 mg/kg | Daily administration for 44 days | To evaluate the effects of Naproxen monotherapy and its combination with KBP on health scores, pain assessments, and bone structure in the CIA rat model. Results showed that Naproxen monotherapy increased the time until humane endpoints were reached, improved health scores, pain assessments, and trabecular thickness, while combination therapy further enhanced efficacy, improved health scores, reduced mechanical and cold allodynia, and protected articular cartilage structure and bone volume. | Arthritis Res Ther. 2019 Feb 22;21(1):68 |
| Rat | Inflammatory Soup Migraine Model | Tail vein injection | 1mg/kg | Single injection, lasting two minutes | To investigate the effects of Sumatriptan/Naproxen on brain networks in a migraine model in rats, the results showed that the combination significantly altered functional connectivity across several brain networks, including the cerebellar, default mode, basal ganglia, autonomic, and salience networks. | Pain. 2019 Sep;160(9):2161-2171 |
| Mice | Lynch syndrome mouse model | Dietary administration | 166 ppm | Continuous administration | Naproxen significantly reduced tumor burden and prolonged survival, and the effect was even more pronounced when combined with FSP vaccination. | Gastroenterology. 2021 Oct;161(4):1288-1302.e13 |
| Rat | DPPIV-F344 rats | Intraperitoneal injection | 2, 4, 6 mg/kg | Single dose, or 8 doses over 3 days after cell transplantation | To investigate the effect of Naproxen on hepatocyte engraftment after transplantation, it was found that Naproxen significantly improved the engraftment of transplanted hepatocytes. | Gastroenterology. 2009 Jun;136(7):2356-64. |
Clinical Trial:
| NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
| NCT00875784 | Migraine Disorders | Phase 1 | Completed | - | United States, Washington ... More >> GSK Investigational Site Tacoma, Washington, United States, 98418 Less << |
| NCT01994226 | Gout | Phase 4 | Completed | - | United Kingdom ... More >> Keele University Stoke-on-Trent, United Kingdom Less << |
| NCT03448536 | Dysmenorrhea | Phase 4 | Completed | - | United States, Arizona ... More >> Radiant Research, Inc. Chandler, Arizona, United States, 85224 Radiant Research, Inc. Scottsdale, Arizona, United States, 85251 United States, Florida Radiant Research, Inc. Pinellas Park, Florida, United States, 33781 United States, Illinois Radiant Research, Inc. Chicago, Illinois, United States, 60602 United States, Ohio Radiant Research, Inc. Akron, Ohio, United States, 44311 Radiant Research, Inc. Cincinnati, Ohio, United States, 45236 United States, Texas Radiant Research, Inc. Dallas, Texas, United States, 75234 Synexus US, LP- Plano Plano, Texas, United States, 75234 Less << |
| NCT02786446 | Renal Stone | Not Applicable | Completed | - | - |
| NCT01994226 | - | Completed | - | - | |
| NCT00959439 | Rheumatoid Arthritis ... More >> Osteoarthritis Less << | Phase 1 | Completed | - | - |
| NCT03658473 | Gastric Lesion | Phase 3 | Completed | - | Brazil ... More >> Galeno Desenvolvimento de Pesquisas Clinicas Ltda. Campinas, SP, Brazil, 13087-010 Less << |
| NCT03347929 | Sciatica | Phase 4 | Recruiting | November 2021 | Norway ... More >> Seksjon for fysikalsk medisin og rehabilitering, Drammen Sykehus, Vestre Viken Recruiting Drammen, Norway, 3004 Contact: Anne Froholdt, MD,PhD Revmatologisk avdeling, Sykehuset Østfold Moss Recruiting Moss, Norway, 1714 Contact: Anne J Haugen, MD,PhD +4791193452 annhau@so-hf.no Fysikalsk medisinsk poliklinikk, Sykehuset Telemark Recruiting Porsgrunn, Norway, 3710 Contact: Anders Sætre, MD Avdeling for fysikalsk medisin og rehabilitering, Stavanger Universitetssjukehus Recruiting Stavanger, Norway, 4068 Contact: Ståle Mathiassen, MD Less << |
| NCT00761501 | Healthy Volunteer | Phase 1 | Completed | - | Sweden ... More >> Research Site Lulea, Sweden Research Site Uppsala, Sweden Less << |
| NCT00804401 | Bioequivalency | Phase 1 | Completed | - | - |
| NCT01165814 | Pain Cesarean... More >> Section Less << | Not Applicable | Completed | - | Israel ... More >> Bnai Zion Medical Center Haifa, Israel Less << |
| NCT01427803 | Pain | Phase 3 | Completed | - | - |
| NCT00803764 | Bioequivalency | Phase 1 | Completed | - | - |
| NCT01612975 | Pleural Effusion ... More >> Pleural Effusion Malignant Less << | Phase 2 | Terminated(Recruitment futile) | - | Canada, Ontario ... More >> St. Joseph's Healthcare Hamilton Hamilton, Ontario, Canada, L8N 4A6 Less << |
| NCT00807846 | Arthritis, Juvenile Rheumatoid | Phase 4 | Completed | - | - |
| NCT01427803 | - | Completed | - | - | |
| NCT00807846 | - | Completed | - | - | |
| NCT00329459 | Migraine Disorders | Phase 3 | Completed | - | - |
| NCT02519231 | Menorrhagia | Phase 4 | Completed | - | United States, Illinois ... More >> John H Stroger Jr Hospital of Cook County Chicago, Illinois, United States, 60612 United States, Washington Harborview Medical Center Seattle, Washington, United States, 98104 UW Neighborhood Clinic Northgate Seattle, Washington, United States, 98125 Hall Health Center Seattle, Washington, United States, 98195 University of Washington Medical Centers Seattle, Washington, United States, 98195 Less << |
| NCT00662896 | Osteoarthritis ... More >> Hypertension Less << | Phase 1 | Completed | - | - |
| NCT02632812 | - | Completed | - | - | |
| NCT02632812 | Gastrointestinal Lesions | Phase 1 | Completed | - | - |
| NCT01525043 | Epicondylitis of the Elbow | Phase 4 | Completed | - | United States, Kansas ... More >> International Clinical Research Institute Overland Park, Kansas, United States, 66210 Less << |
| NCT03161093 | Osteoarthritis, Knee ... More >> Osteoarthritis, Hip Less << | Phase 3 | Recruiting | April 5, 2021 | - |
| NCT02255955 | Postoperative Pain ... More >> Postoperative Laminectomy Pain Less << | Phase 4 | Unknown | December 2014 | - |
| NCT01090596 | Healthy | Not Applicable | Completed | - | - |
| NCT00222976 | Post-Vaginal Delivery Perineal... More >> Pain Less << | Phase 4 | Completed | - | Canada, Saskatchewan ... More >> Department of Anesthesia, Royal University Hospital, University of Saskatchewan Saskatoon, Saskatchewan, Canada, S7N 0W8 Less << |
| NCT00383487 | Prostatic Neoplasms ... More >> Prostate Cancer Less << | Phase 2 | Terminated(Extreme toxicity) | - | United States, California ... More >> Stanford University School of Medicine Stanford, California, United States, 94305 Less << |
| NCT00503828 | Knee Osteoarthritis | Phase 3 | Completed | - | Thailand ... More >> Siriraj Hospital Bangkoknoi, Bangkok, Thailand, 10700 Less << |
| NCT01090050 | Chronic Migraine | Phase 4 | Completed | - | United States, Missouri ... More >> Clinvest Springfield, Missouri, United States, 65807 United States, Texas Texas Headache Associates San Antonio, Texas, United States, 78258 Less << |
| NCT00449787 | - | Completed | - | - | |
| NCT00385008 | Migraine Disorders | Phase 3 | Completed | - | United States, Kentucky ... More >> GSK Investigational Site Lexington, Kentucky, United States, 40503 Less << |
| NCT00449787 | Migraine Tens... More >>ion-type Headache Primary Headache Disorder Less << | Phase 4 | Completed | - | United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Columbia University Medical Center New York, New York, United States, 10032 Less << |
| NCT00385008 | - | Completed | - | - | |
| NCT00615875 | Pain, Postoperative | Phase 4 | Unknown | June 2008 | Canada, Ontario ... More >> St. Joseph's Healthcare Hamilton Not yet recruiting Hamilton, Ontario, Canada, L8N 4A6 Principal Investigator: Victoria Luckham, BScPhm Less << |
| NCT00893594 | Migraine With Aura | Not Applicable | Unknown | December 2015 | United States, New York ... More >> Dent Neurologic Institute Recruiting Amherst, New York, United States, 14226 Contact: Rebecca M Hogan, BS 716-558-5670 rhogan@dentinstitute.com Contact: Mary K Betz, P.A. 716-558-5662 mbetz@dentinstitute.com Principal Investigator: Laszlo L Mechtler, M.D. Less << |
| NCT01090050 | - | Completed | - | - | |
| NCT00790985 | Osteoarthritis | Not Applicable | Completed | - | - |
| NCT00907400 | Healthy | Phase 1 | Completed | - | Sweden ... More >> Research Site Lulea, Sweden Research Site Uppsala, Sweden Less << |
| NCT01409603 | Pharmacodynamic Interaction ... More >> Healthy Subjects Less << | Phase 1 | Completed | - | France ... More >> SGS Aster Paris, France, 75015 Less << |
| NCT00843024 | Migraine Disorders | Phase 3 | Completed | - | - |
| NCT00843024 | - | Completed | - | - | |
| NCT00665743 | Arthritis | Phase 1 | Completed | - | United States, Texas ... More >> Austin, Texas, United States Less << |
| NCT01450995 | Migraine | Phase 4 | Completed | - | United States, Tennessee ... More >> Wesley Headache Clinic Memphis, Tennessee, United States, 38018 Less << |
| NCT00153660 | Arthritis Car... More >>diovascular Diseases Cerebrovascular Disorders Less << | Phase 3 | Completed | - | China, Hong Kong ... More >> Endoscopy Center, Prince of Wales Hospital Shatin, Hong Kong, China Less << |
| NCT00692016 | Bioavailability | Phase 1 | Completed | - | United States, Arkansas ... More >> Little Rock, Arkansas, United States, 72202 Less << |
| NCT03167541 | Healthy | Phase 1 | Completed | - | - |
| NCT01381497 | - | Completed | - | - | |
| NCT01390324 | Migraine Head... More >>ache Less << | Phase 3 | Withdrawn | - | - |
| NCT01063920 | Osteoarthritis | Phase 2 Phase 3 | Completed | - | - |
| NCT00240630 | Migraine Disorders ... More >> Migraine Less << | Phase 3 | Completed | - | - |
| NCT02183038 | Pharyngitis | Phase 2 | Completed | - | - |
| NCT00692055 | Arthritis | Phase 1 | Completed | - | United States, Texas ... More >> Austin, Texas, United States Less << |
| NCT00596245 | Healthy | Phase 1 | Completed | - | United States, Texas ... More >> Matthew M. Medlock, MD Austin, Texas, United States, 78744 Less << |
| NCT02769247 | - | Completed | - | - | |
| NCT02769247 | Contraception ... More >> Pain Less << | Not Applicable | Completed | - | United States, Maryland ... More >> Walter Reed National Military Medical Center Bethesda, Maryland, United States, 20889 Less << |
| NCT01995006 | Healthy | Phase 1 | Completed | - | Switzerland ... More >> Phase I Research Unit, University Hospital Basel, Switzerland Less << |
| NCT00751556 | Healthy | Phase 1 | Completed | - | United States, Arkansas ... More >> Little Rock, Arkansas, United States, 72202 Less << |
| NCT02463552 | Toothache Too... More >>th Bleaching Less << | Not Applicable | Completed | - | Brazil ... More >> Universidade Federal de Sergipe Aracaju, SE, Brazil, 49060100 Less << |
| NCT00928837 | Osteoarthritis | Not Applicable | Completed | - | United States, Pennsylvania ... More >> Alan Kivitz MD Duncansville, Pennsylvania, United States, 16635 Less << |
| NCT00789802 | - | Completed | - | - | |
| NCT00789802 | Contraception ... More >> Bleeding Less << | Not Applicable | Completed | - | United States, Missouri ... More >> Washington University School fo Medicine Saint Louis, Missouri, United States, 63110 Less << |
| NCT01118273 | Sleep | Phase 4 | Completed | - | United States, Utah ... More >> Salt Lake City, Utah, United States, 84124 Less << |
| NCT01666678 | Therapeutic Equivalence | Phase 1 | Completed | - | United States, New Jersey ... More >> Hackensack, New Jersey, United States, 07601 Less << |
| NCT00749385 | Arthritis | Phase 1 | Completed | - | United States, Texas ... More >> PPD Austin, Texas, United States, 78744 Less << |
| NCT02501564 | Osteoarthritis | Phase 4 | Completed | - | - |
| NCT00751400 | Pain | Phase 3 | Completed | - | United States, California ... More >> Anaheim, California, United States, 92801 Oceanside, California, United States, 92054 San Dimas, California, United States, 91773 United States, Kansas Overland Park, Kansas, United States, 66209 United States, Minnesota Anoka, Minnesota, United States, 55303 Blaine, Minnesota, United States, 55443 Elk River, Minnesota, United States, 55330 St. Francis, Minnesota, United States, 55070 St. Louis Park, Minnesota, United States, 55426 United States, Missouri Belton, Missouri, United States, 64012 Savannah, Missouri, United States, 64485 St. Joseph, Missouri, United States, 64504 United States, North Carolina Cary, North Carolina, United States, 27513 Chapel Hill, North Carolina, United States, 27514 Raleigh, North Carolina, United States, 27606 Raleigh, North Carolina, United States, 27612 United States, Utah Bountiful, Utah, United States, 84010 Ogden, Utah, United States, 84401 Salt Lake City, Utah, United States, 84102 Syracuse, Utah, United States, 84075 West Jordan, Utah, United States, 84088 United States, Washington Kenmore, Washington, United States, 98028 Seattle, Washington, United States, 98148 Snohomish, Washington, United States, 98290 Less << |
| NCT01118273 | - | Completed | - | - | |
| NCT01726920 | Migraine Head... More >>ache Less << | Phase 3 | Withdrawn(Due to budget limita... More >>tions, the company decided to withdraw this study.) Less << | - | - |
| NCT02549469 | Pain | Phase 1 | Completed | - | - |
| NCT00662610 | Osteoarthritis ... More >> Hypertension Less << | Phase 1 | Completed | - | - |
| NCT00992381 | Healthy | Phase 1 | Completed | - | Australia, Queensland ... More >> Research Site Brisbane, Queensland, Australia Less << |
| NCT01300546 | - | Completed | - | - | |
| NCT01300546 | Migraine | Phase 4 | Completed | - | United States, California ... More >> Newport Beach Clinical Research Assoc., Inc. Newport Beach, California, United States, 92663 United States, Missouri Clinvest Springfield, Missouri, United States, 65807 Less << |
| NCT00751400 | - | Completed | - | - | |
| NCT00601458 | - | Completed | - | - | |
| NCT01381523 | - | Completed | - | - | |
| NCT00527787 | Gastric Ulcer | Phase 3 | Completed | - | United States, North Carolina ... More >> POZEN Chapel Hill, North Carolina, United States, 27517 Less << |
| NCT00382993 | Migraine Disorders | Phase 3 | Completed | - | - |
| NCT00382993 | - | Completed | - | - | |
| NCT00383162 | Migraine Disorders | Phase 3 | Completed | - | - |
| NCT01129011 | Gastric Ulcer | Phase 3 | Completed | - | - |
| NCT01129011 | - | Completed | - | - | |
| NCT03404206 | Pain, Postoperative | Phase 4 | Completed | - | United States, Utah ... More >> Jean Brown Research Salt Lake City, Utah, United States, 84124 Less << |
| NCT01365052 | Pain | Phase 3 | Completed | - | United States, Arizona ... More >> Chandler, Arizona, United States, 85224 Mesa, Arizona, United States, 85203 Peoria, Arizona, United States, 85381 United States, California Anaheim, California, United States, 92801 Rancho Cucamonga, California, United States, 91730 Sacramento, California, United States, 95816 United States, Colorado Colorado Springs, Colorado, United States, 80922 United States, Florida Kissimmee, Florida, United States, 34741 Pembroke Pines, Florida, United States, 33028 South Miami, Florida, United States, 33143 United States, Georgia Stockbridge, Georgia, United States, 30281 United States, Louisiana Metairie, Louisiana, United States, 70006 United States, Maryland Elkridge, Maryland, United States, 21075 United States, Rhode Island Warwick, Rhode Island, United States, 02886 United States, South Carolina Mt. Pleasant, South Carolina, United States, 29464 United States, Texas Fort Worth, Texas, United States, 76135 San Angelo, Texas, United States, 76904 San Antonio, Texas, United States, 78231 United States, Utah Salt Lake City, Utah, United States, 84106 Less << |
| NCT00527787 | - | Completed | - | - | |
| NCT02052908 | Lynch Syndrome | Phase 1 | Active, not recruiting | - | United States, Massachusetts ... More >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 United States, Michigan University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan, United States, 48109 United States, Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 United States, Utah Huntsman Cancer Institute/University of Utah Salt Lake City, Utah, United States, 84112 Less << |
| NCT01365052 | - | Completed | - | - | |
| NCT02351024 | Pharmacokinetics | Phase 1 | Completed | - | United Kingdom ... More >> Quotient Clinical Ltd Nottingham, United Kingdom Less << |
| NCT03424135 | Pain | Phase 1 | Completed | - | United States, Texas ... More >> ICON Development Solutions, LLC San Antonio, Texas, United States, 78219 Less << |
| NCT00966641 | Healthy Volunteers | Phase 1 Phase 2 | Completed | - | United States, Texas ... More >> Houston Institute for Clinical Research Houston, Texas, United States, 77074 Less << |
| NCT00601458 | Acute Pain | Phase 1 | Completed | - | - |
| NCT03396250 | Pain | Phase 1 | Completed | - | United States, Texas ... More >> ICON Development Solutions, LLC San Antonio, Texas, United States, 78219 Less << |
| NCT00966641 | - | Completed | - | - | |
| NCT01280591 | Pain, Postoperative | Phase 3 | Completed | - | United States, Texas ... More >> Austin, Texas, United States, 78744 United States, Utah Salt Lake City, Utah, United States, 84124 Less << |
| NCT01280591 | - | Completed | - | - | |
| NCT00720057 | - | Completed | - | - | |
| NCT00586365 | Heterotopic Ossification | Phase 4 | Withdrawn(Too difficult to sat... More >>isfy all the inclusion criteria.) Less << | - | United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Less << |
| NCT00720057 | Toothache | Phase 3 | Completed | - | United States, Texas ... More >> Austin, Texas, United States, 78705 Austin, Texas, United States, 78744 United States, Utah Salt Lake City, Utah, United States, 84124 Less << |
| NCT02229461 | - | Completed | - | - | |
| NCT02229461 | Hematology | Phase 1 | Completed | - | United States, Texas ... More >> Austin, Texas, United States, 78744 Less << |
| NCT00383162 | - | Completed | - | - | |
| NCT02388191 | Contraception | Not Applicable | Completed | - | United States, Massachusetts ... More >> Planned Parenthood League of Massachusetts Boston, Massachusetts, United States, 02215 Less << |
| NCT02702817 | Alzheimer Disease ... More >> Cognitive Decline Due to Alzheimer Disease Mild Cognitive Impairment Due to Alzheimer Disease Less << | Phase 2 | Completed | - | Canada, Quebec ... More >> Douglas Hospital Research Centre Montreal, Quebec, Canada, H4H1R3 Less << |
| NCT01539447 | Heterotopic Ossification | Early Phase 1 | Active, not recruiting | January 2019 | United States, Utah ... More >> University of Utah Orthopedics Center Salt Lake City, Utah, United States, 84108 Less << |
| NCT00818415 | Pain | Phase 1 | Completed | - | United States, Texas ... More >> Austin, Texas, United States, 78744 Less << |
| NCT01557816 | Osteoarthritis, Knee | Not Applicable | Unknown | June 2012 | United States, Massachusetts ... More >> Analgesic Solutions Recruiting Natick, Massachusetts, United States, 01760 Contact: Stephen Wright, MD 781-444-9605 ext 101 swright@analgesicsolutions.com Contact: Pura Requintina, Ph.D. 781-444-9605 ext 121 prequintina@analgesicsolutions.com Principal Investigator: Stephen Wright, MD Less << |
| NCT02388191 | - | Completed | - | - | |
| NCT02494856 | Pain Other Su... More >>rgical Procedures Impacted Third Molar Tooth Less << | Phase 4 | Completed | - | Brazil ... More >> University of São Paulo Bauru, SP, Brazil, 17012-901 Less << |
| NCT00792636 | Migraine Disorders | Phase 4 | Completed | - | - |
| NCT03566979 | Post-operative Dental Pain | Phase 3 | Recruiting | May 10, 2019 | United States, Utah ... More >> JBR Clinical Research Recruiting Salt Lake City, Utah, United States, 84124 Less << |
| NCT01495858 | Pain, Postoperative | Phase 3 | Completed | - | United States, Texas ... More >> Austin, Texas, United States, 78744 United States, Utah Salt Lake City, Utah, United States, 84106 Less << |
| NCT01495858 | - | Completed | - | - | |
| NCT00792636 | - | Completed | - | - | |
| NCT01389284 | Pain, Postoperative | Phase 3 | Completed | - | United States, Texas ... More >> Austin, Texas, United States, 78744 Less << |
| NCT00488514 | Migraine Disorders | Phase 3 | Completed | - | - |
| NCT01389284 | - | Completed | - | - | |
| NCT01952652 | Arthroscopic Meniscus Surgery | Phase 4 | Completed | - | Turkey ... More >> Baskent University School of Medicine Adana Teaching and Research Hospital Adana, Turkey, 01250 Less << |
| NCT03092193 | Poor Metabolizer Due to Cytoch... More >>rome P450 CYP2C9 Variant Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant Less << | Phase 4 | Recruiting | December 2018 | Brazil ... More >> Bauru School of Dentistry/USP Recruiting Bauru, São Paulo, Brazil, 17012-901 Contact: Adriana M Calvo, PhD 551432358276 birinjela@yahoo.com.br Less << |
| NCT01052792 | Healthy | PHASE1 | COMPLETED | 2025-06-06 | Wellquest Clinical Research, M... More >>umbai, Maharashtra, 400 013, India Less << |
| NCT00488514 | - | Completed | - | - | |
| NCT01383486 | - | Completed | - | - | |
| NCT01131728 | Healthy | Phase 1 | Completed | - | India ... More >> Lotus Labs Private Limited Bangalore, Karnataka, India, 560034 Less << |
| NCT01383486 | Pain | Phase 3 | Completed | - | United States, California ... More >> Anaheim, California, United States, 92801 Yorba Linda, California, United States, 92886 United States, Florida Pembroke Pines, Florida, United States, 33026 United States, Georgia Griffin, Georgia, United States, 30224 United States, Minnesota Andover, Minnesota, United States, 55304 Roseville, Minnesota, United States, 55113 United States, Utah Bountiful, Utah, United States, 84010 West Jordan, Utah, United States, 84088 United States, Washington Bellevue, Washington, United States, 98007 Seattle, Washington, United States, 98122 Less << |
| NCT01052129 | Healthy | Phase 1 | Completed | - | India ... More >> Wellquest Clinical Research Mumbai, Maharashtra, India, 400 013 Less << |
| NCT03291418 | Gastric Ulcer | Phase 1 Phase 2 | Completed | - | Canada, Ontario ... More >> Topstone Clinical Research Toronto, Ontario, Canada, M9C 4Z5 Less << |
| NCT01131767 | Healthy | Phase 1 | Completed | - | India ... More >> Lotus Labs Private Limited Bangalore, Karnataka, India, 560034 Less << |
| NCT00969449 | Pharmacokinetics | Phase 1 | Completed | - | United States, Texas ... More >> Austin, Texas, United States, 78744 Less << |
| NCT03697889 | Healthy | Phase 1 | Not yet recruiting | March 31, 2019 | Russian Federation ... More >> LLC "Scientific and Research centre Eco-safety" Not yet recruiting St.Petersburg, Russian Federation, 196143 Less << |
| NCT02143713 | Endometriosis | Phase 3 | Completed | - | - |
| NCT01339156 | Acute Dental Pain | Phase 1 | Terminated | - | - |
| NCT01931670 | Endometriosis | Phase 3 | Completed | - | - |
| NCT02143713 | - | Completed | - | - | |
| NCT01620528 | Endometriosis | Phase 3 | Completed | - | - |
| NCT01638962 | Osteoarthritis, Knee | Not Applicable | Completed | - | Denmark ... More >> University of Southern Denmark Odense, Region Syddanmark, Denmark, 5230 Less << |
| NCT01620528 | - | Completed | - | - | |
| NCT01511627 | Hysterectomy | Not Applicable | Withdrawn(Research question wa... More >>s answered by Acta Anaesthesiol Scand 2012; 56 102-109.) Less << | - | Canada, Saskatchewan ... More >> Saskatoon City Hospital Saskatoon, Saskatchewan, Canada, S7K0M7 Less << |
| NCT02094807 | Trauma Rib Fr... More >>actures Surgery Pain Less << | Not Applicable | Withdrawn(Slow inclusion rate.... More >> Awaiting results from NCT02132416.) Less << | May 2020 | Sweden ... More >> Sahlgrenska University Hospital Gothenburg, Sweden, 413 45 Less << |
| NCT02132416 | Trauma Flail ... More >>Chest Rib Fractures Surgery Less << | Not Applicable | Active, not recruiting | December 2018 | Sweden ... More >> Departement of Surgery, Sahlgrenska University Hospital Gothenburg, Sweden, 413 45 Departement of Intensive Care, Karolinska University Hospital Stockholm, Sweden, 171 76 Less << |
| NCT00551135 | Pain, Postoperative ... More >> Hernia, Inguinal Less << | Phase 3 | Completed | - | - |
| NCT00285649 | Low Back Pain | Not Applicable | Completed | - | United States, Iowa ... More >> Palmer Center for Chiropractic Research Davenport, Iowa, United States, 52803 Less << |
| NCT02397785 | - | Completed | - | - | |
| NCT01003639 | - | Completed | - | - | |
| NCT01003639 | Idiopathic Intracranial Hypert... More >>ension Less << | Phase 2 Phase 3 | Completed | - | - |
| NCT00551135 | - | Completed | - | - | |
| NCT02397785 | Pelvic Pain | Not Applicable | Completed | - | United States, Ohio ... More >> Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195 Less << |
| NCT00447759 | Osteoarthritis ... More >> Rheumatoid Arthritis Less << | Phase 4 | Completed | - | Denmark ... More >> University of Southern Denmark Odense, Denmark, 5000 Netherlands Julius Clinical Research Zeist, Netherlands, 3703 CD Zeist United Kingdom University of Aberdeen Aberdeen, United Kingdom, AB25 2ZN University of Birmingham Birmingham, United Kingdom, B15 2TT University of Dundee Dundee, United Kingdom, DD1 9SY University of Edinburgh Edinburgh, United Kingdom, EH4 2XU University of Glasgow Glasgow, United Kingdom, G11 6NT NHS Highlands Inverness, United Kingdom, IV2 3JH University of Nottingham Nottingham, United Kingdom, NG7 2UH University of Oxford Oxford, United Kingdom, OX1 2ET Less << |
| NCT01931670 | - | Completed | - | - | |
| NCT01916395 | - | Completed | - | United States, Michigan ... More >> Westside Family Medical Center, PC Kalamazoo, Michigan, United States, 49009 Less << | |
| NCT00285649 | - | Completed | - | - | |
| NCT00621881 | Liver Disease | Phase 1 | Completed | - | United States, Florida ... More >> Miami, Florida, United States Less << |
| NCT02945839 | Migraine | Phase 4 | Not yet recruiting | December 2018 | United States, New York ... More >> New York University School of Medicine Not yet recruiting New York, New York, United States, 10016 Contact: Liliana Serrano Liliana.Serrano2@nyumc.org Principal Investigator: mia Minen, MD Less << |
| NCT01761864 | Study Focus: Prescribing of Dr... More >>ugs Less << | Not Applicable | Unknown | January 2016 | Belgium ... More >> University of Antwerp Wilrijk, Belgium, 2610 Less << |
| NCT02322996 | - | Withdrawn(never started) | - | United States, North Carolina ... More >> School of Dental Medicine At East Carolina University Greenville, North Carolina, United States, 27834 Less << | |
| NCT00688545 | - | Terminated(See termination rea... More >>son in detailed description.) Less << | - | - | |
| NCT00688545 | - | Terminated(See termination rea... More >>son in detailed description.) Less << | - | - | |
| NCT01094483 | Platelet Inhibition | Phase 1 | Completed | - | United States, Kansas ... More >> Research Site Overland Park, Kansas, United States Less << |
| NCT03245008 | Osteoarthritis, Knee / Osteoar... More >>thritis, Hip Less << | Phase 2 Phase 3 | Recruiting | January 2021 | Japan ... More >> Investigational Site Recruiting Aichi, Japan Investigational Site Recruiting Aomori, Japan Investigational Site Recruiting Chiba, Japan Investigational Site Recruiting Ehime, Japan Investigational Site Recruiting Fukui, Japan Investigational Site Recruiting Fukuoka, Japan Investigational Site Recruiting Fukushima, Japan Investigational Site Recruiting Gunma, Japan Investigational Site Recruiting Hiroshima, Japan Investigational Site Recruiting Hokkaido, Japan Investigational Site Recruiting Hyogo, Japan Investigational Site Recruiting Ibaraki, Japan Investigational Site Recruiting Kagoshima, Japan Investigational Site Recruiting Kanagawa, Japan Investigational Site Recruiting Kumamoto, Japan Investigational Site Recruiting Kyoto, Japan Investigational Site Recruiting Mie, Japan Investigational Site Recruiting Miyagi, Japan Investigational Site Recruiting Miyazaki, Japan Investigational Site Recruiting Oita, Japan Investigational Site Recruiting Osaka, Japan Investigational Site Recruiting Saitama, Japan Investigational Site Recruiting Shiga, Japan Investigational Site Recruiting Shizuoka, Japan Investigational Site Recruiting Tokyo, Japan Investigational Site Recruiting Yamagata, Japan Investigational Site Recruiting Yamaguchi, Japan Less << |
| NCT03220633 | Chronic Pain | Phase 1 | Completed | - | Canada, Quebec ... More >> Algorithme Pharma Montreal, Quebec, Canada Less << |
| NCT02707094 | Chronic Low Back Pain | Not Applicable | Completed | - | United States, Texas ... More >> Brooke Army Medical Center Fort Sam Houston, Texas, United States, 78234 Less << |
| NCT01267825 | Disc Herniation ... More >> Lumbosacral Radiculopathy Less << | Phase 4 | Terminated(Study terminated ea... More >>rly due to low enrollment. No data collected.) Less << | - | United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less << |
| NCT00809354 | Osteoarthritis ... More >> Arthritis Less << | Phase 3 | Terminated(See termination rea... More >>son in detailed description.) Less << | - | - |
| NCT03031938 | Osteoarthritis ... More >> Cancer Pain Recurrent Low Back Pain Less << | Phase 3 | Recruiting | April 4, 2022 | United States, California ... More >> USC Keck School of Medicine Recruiting Los Angeles, California, United States, 90033 United States, Florida Gulfcoast Research Institute Recruiting Sarasota, Florida, United States, 34232 Kennedy and White Orthopaedic Center Recruiting Sarasota, Florida, United States, 34232 Pediatric Epilepsy & Neurology Specialists Recruiting Tampa, Florida, United States, 33609 United States, Indiana Lafayette Clinical Research Group Active, not recruiting Lafayette, Indiana, United States, 47905 Preferred Pediatrics Active, not recruiting Lafayette, Indiana, United States, 47905 Less << |
| NCT01267825 | - | Terminated(Study terminated ea... More >>rly due to low enrollment. No data collected.) Less << | - | - | |
| NCT00665431 | - | Completed | - | - | |
| NCT01298531 | Axial Spondyloarthritis | Phase 4 | Completed | - | France ... More >> Institut Calot - Fondation Hopale Berck-sur-Mer, France, 62608 Hopital Pellegrin Bordeaux Cedex, France, 33076 Centre Hospitalier, Service de Rhumatologie Cahors, France, 46000 CHU Hopital Gabriel Montpied Clermont-Ferrand, France, 63003 Centre Hospitalier Sud Francilien Corbeil Essonnes, France, 91100 Hopital Bicetre LE KREMLIN-BICETRE Cedex, France, 94275 CH Le Mans Le Mans, France, 72037 Chu Dupuytren, Rhumatologie et Therapeutique Limoges, France, 87042 CHU Lapeyronie, Immuno-Rhumatologie Montpellier, France, 34000 Hopital de l'Archet Nice, France, 06202 Hopital Porte Madeleine Orleans Cedex 1, France, 45032 H�al Saint-Antoine Paris, France, 75012 Hopital Cochin Paris, France, 75014 Hopital Saint Joseph - Service de Rhumatologie Paris, France, 75014 Hopital Bichat Paris, France, 75018 Service de Rhumatologie Paris, France, 75651 Cedex 13 CHU Bois Guillaume - Service de Rhumatologie Rouen, France, 76031 CHU de Saint Etienne, Hopital Nord Saint Etienne Cedex 2, France, 42055 Hopital Purpan Toulouse Cedex 09, France, 31059 Less << |
| NCT01298531 | - | Completed | - | - | |
| NCT00664560 | - | Completed | - | - | |
| NCT00664560 | Osteoarthritis | Phase 3 | Completed | - | United States, North Carolina ... More >> POZEN Chapel Hill, North Carolina, United States, 27517 Less << |
| NCT02674386 | Osteoarthritis | Phase 3 | Recruiting | August 12, 2019 | - |
| NCT00001955 | Temporomandibular Joint Disord... More >>er Less << | Phase 2 | Completed | - | United States, Maryland ... More >> National Institute of Dental And Craniofacial Research (NIDCR) Bethesda, Maryland, United States, 20892 Less << |
| NCT00599404 | Healthy | Phase 1 | Completed | - | - |
| NCT00665431 | Osteoarthritis | Phase 3 | Completed | - | United States, North Carolina ... More >> POZEN Chapel Hill, North Carolina, United States, 27517 Less << |
| NCT00737737 | Chronic Pain ... More >>Osteoarthritis Less << | Phase 4 | Completed | - | United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less << |
| NCT00737737 | - | Completed | - | - | |
| NCT00065559 | Diabetic Nephropathy | Not Applicable | Terminated | - | United States, Illinois ... More >> Rush Presbyterian St. Luke's Medical Center Chicago, Illinois, United States, 60612 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less << |
| NCT01355549 | Shoulder Pain ... More >> Rotator Cuff Tendinitis Rotator Cuff Syndrome Spinal Cord Injury Less << | Phase 1 | Completed | - | United States, New Jersey ... More >> Kessler Institute for Rehabilitation West Orange, New Jersey, United States, 07052 Less << |
| NCT02771249 | Healthy Volunteers | Phase 1 | Recruiting | December 31, 2019 | United States, Maryland ... More >> National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 prpl@cc.nih.gov Less << |
| NCT01843179 | Acute Myeloid Leukemia | Phase 2 | Withdrawn(Lack of Funding) | - | United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02115 Less << |
| NCT02929589 | Pain Hernia | Phase 3 | Recruiting | April 2020 | United States, Nevada ... More >> Mike O'Callaghan Federal Medical Center Recruiting Nellis Air Force Base, Nevada, United States, 89191 Contact: Jill M Clark, MBA/HCM 702-653-3298 jill.m.clark15.ctr@mail.mil Principal Investigator: William Scott, DO Less << |
| NCT02580344 | Contraception | Phase 2 | Completed | - | Egypt ... More >> Assiut university Assiut, Egypt, 71111 Less << |
| NCT02903680 | Migraine | Phase 1 | Recruiting | June 2019 | Canada, Quebec ... More >> CHU Sainte Justine Recruiting Montréal, Quebec, Canada, H3T1C4 Contact: Geneviève Tourigny-Ruel 5149143133 getruel@yahoo.ca Principal Investigator: Benoit Bailey, MD Sub-Investigator: Jocelyn Gravel, MD Less << |
| NCT01511926 | - | Completed | - | - | |
| NCT01481103 | Migraine Headache | Not Applicable | Terminated(PI cited personal r... More >>easons) Less << | - | United States, Illinois ... More >> Serenity Acupuncture and Oriental Medicine Oak Park, Illinois, United States, 60302 Less << |
| NCT00543868 | Stomach Ulcer ... More >> Duodenal Ulcer Less << | Phase 2 | Completed | - | - |
| NCT02139046 | - | Completed | - | - | |
| NCT02128490 | Gout Moderate... More >> Renal Impairment Less << | Phase 2 | Completed | - | - |
| NCT03472469 | Nonspecific Pain Post Traumati... More >>c Injury Less << | Phase 4 | Enrolling by invitation | October 1, 2019 | United States, Texas ... More >> The University of Texas Health Science Center at Houston Houston, Texas, United States, 77030 Less << |
| NCT02139046 | Gout | Phase 3 | Completed | - | - |
| NCT01982799 | Odontalgia | Not Applicable | Withdrawn(Not enough funding) | - | United States, Minnesota ... More >> University of Minnesota School of Dentistry Minneapolis, Minnesota, United States, 55455 Less << |
| NCT01071317 | Migraine | Phase 4 | Completed | - | United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less << |
| NCT02643719 | Migraine | Not Applicable | Withdrawn(Study team missed co... More >>ntinuing review and study lapsed with out recruiting any subjects.) Less << | - | - |
| NCT02689024 | Hip Fractures ... More >> Anesthesia Less << | Phase 4 | Recruiting | July 2019 | Netherlands ... More >> Meander Medical Center Recruiting Amersfoort, Netherlands, 3813 TZ Contact: Maurice Pouw, MD 033 850 5050 me.pouw@meandermc.nl Slotervaart Medical Center Recruiting Amsterdam, Netherlands, 1066 EC Contact: Daniel Haverkamp, MD, PhD 020 - 512 93 33 Daniël.Haverkamp@slz.nl VU Medical Center Recruiting Amsterdam, Netherlands, 1081 HV Contact: Edwin Vandewalle, MD 0031(0)20-4444444 e.vandewalle@vumc.nl Academic Medical Center Recruiting Amsterdam, Netherlands, 1105 AZ Contact: Milan Ridderikhof, MD 0031-(0)20-5663336 m.l.ridderikhof@amc.uva.nl Contact: Helma Goddijn, MSc 0031-(0)20-5663336 w.m.t.goddijn@amc.uva.nl Less << |
| NCT02522130 | IUD Insertion Complication | Not Applicable | Unknown | December 2016 | Egypt ... More >> Menoufia University Recruiting Shebin Elkom, Egypt Contact: nabih elkholy, MD 00201060868443 Saudi Arabia Alhayah national hospital Recruiting Abha, Saudi Arabia Contact: mohamed maher +966558198655 Contact: tarek sayyed Principal Investigator: mohamed maher Less << |
| NCT02128490 | - | Completed | - | - | |
| NCT02293681 | - | Terminated(The project was sto... More >>pped by 31-May-2017 because of internal owner decision from out of balance enrollment from two groups.) Less << | - | China ... More >> Beijing, China Changsha, China Chengdu, China Guangzhou, China Shanghai, China Xi'An, China Xian, China Less << | |
| NCT01578941 | Menstrual Migraine | Phase 4 | Completed | - | United States, Alabama ... More >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35233 Less << |
| NCT02528188 | Chronic Pain ... More >>Osteoarthritis, Hip Osteoarthritis, Knee Less << | Phase 3 | Active, not recruiting | February 2019 | - |
| NCT00447486 | Osteoarthritis, Knee | Phase 2 | Completed | - | Denmark ... More >> GSK Investigational Site Hvidovre, Denmark, 2650 GSK Investigational Site Odense C, Denmark, 5000 Germany GSK Investigational Site Muenchen, Bayern, Germany, 80333 GSK Investigational Site Essen, Nordrhein-Westfalen, Germany, 45359 GSK Investigational Site Koeln, Nordrhein-Westfalen, Germany, 51069 GSK Investigational Site Leipzg, Sachsen, Germany, 04109 GSK Investigational Site Schmiedeberg, Sachsen, Germany, 01762 GSK Investigational Site Berlin, Germany, 10559 GSK Investigational Site Berlin, Germany, 10787 GSK Investigational Site Berlin, Germany, 12051 GSK Investigational Site Hamburg, Germany, 20249 Spain GSK Investigational Site Centelles, Spain GSK Investigational Site La Coruña, Spain, 15006 GSK Investigational Site Madrid, Spain, 28046 GSK Investigational Site Petrer/Alicante, Spain GSK Investigational Site Santiago de Compostela, Spain, 15706 Sweden GSK Investigational Site Göteborg, Sweden, SE-412 55 GSK Investigational Site Göteborg, Sweden, SE-416 85 GSK Investigational Site Helsingborg, Sweden, SE-252 78 GSK Investigational Site Höllviken, Sweden, SE-236 51 GSK Investigational Site Stocholm, Sweden, SE-17176 GSK Investigational Site Upplands Väsby, Sweden, SE-194 89 Less << |
| NCT00261586 | Analgesics | Phase 4 | Completed | - | - |
| NCT01071317 | - | Completed | - | - | |
| NCT00442208 | Healthy | Phase 1 | Completed | - | United States, North Carolina ... More >> Pozen Inc. Chapel Hill, North Carolina, United States, 27517 Less << |
| NCT00913627 | Pain | Phase 2 | Completed | - | United States, Utah ... More >> Jean Brown Research Center Salt Lake City, Utah, United States, 84124 Less << |
| NCT02108548 | Pharmacokinetics of ASP7657 ... More >> Pharmacodynamics of ASP7657 Healthy Subjects Less << | Phase 1 | Terminated(Gastrointestinal sa... More >>fety findings) Less << | - | United Kingdom ... More >> Parexel Early Phase Clinical Unit Harrow, Middlesex, United Kingdom, HA1 3UJ Less << |
| NCT01343303 | Osteoarthritis, Knee | Phase 1 | Completed | - | South Africa ... More >> George, South Africa Less << |
| NCT01442428 | Immune Reconstitution Inflamma... More >>tory Syndrome Immune Reconstitution Syndrome Tuberculosis HIV-infection/Aids Less << | Phase 2 Phase 3 | Withdrawn(2011 Thailand floodi... More >>ng led to loss of GMP pharmacy, project delays, and further regulatory challenges.) Less << | June 2016 | Thailand ... More >> Ramathibodi Hospital Bangkok, Thailand Chiang Mai University Chiang Mai, Thailand Bamrasnaradura Infectious Diseases Institute Nonthaburi, Thailand Less << |
| NCT00913627 | - | Completed | - | - | |
| NCT03351439 | Hip Pain Chronic | Not Applicable | Recruiting | December 31, 2018 | Canada, Ontario ... More >> Fowler Kennedy Sport Medicine Clinic Recruiting London, Ontario, Canada, N6A 3K7 Contact: Ryan M Degen, MD 519-661-2171 ryan.degen@lhsc.on.ca Contact: Stacey Wanlin swanlin@uwo.ca Principal Investigator: Ryan M Degen, MD Principal Investigator: Kevin Willits, MD Less << |
| NCT00674856 | Renal Failure | Phase 1 | Completed | - | United States, Florida ... More >> Orlando, Florida, United States United States, Minnesota Minneapolis, Minnesota, United States St. Paul, Minnesota, United States Less << |
| NCT02307305 | Neuropathic Pain | Phase 2 | Unknown | December 2016 | Korea, Republic of ... More >> Department of Orthopaedic Surgery, Hanyang University, College of Medicine Recruiting Seoul, Korea, Republic of, 133-792 Contact: Jinkyu Lee +82-10-9582-7004 gaia-silver@hanmail.net Less << |
| NCT00826462 | Tennis Elbow ... More >>Epicondylitis, Lateral Humeral Less << | Phase 4 | Completed | - | Norway ... More >> Grålum legesenter Sarpsborg, Norway, 1712 Less << |
| NCT01417130 | - | Unknown | August 2012 | United States, Arizona ... More >> Banner Sun Health Research Institute Sun City, Arizona, United States, 85351 United States, Florida The Roskamp Institute Sarasota, Florida, United States, 34243 United States, Maryland The Johns Hopkins University Baltimore, Maryland, United States, 21205 United States, Massachusetts Boston University School of Medicine Boston, Massachusetts, United States, 02118 United States, New York Monroe Community Hospital Rochester, New York, United States, 14620 United States, Washington Veterans Affairs Puget Sound Health Care System Seattle, Washington, United States, 98108 Less << | |
| NCT02268305 | Low Back Pain | Phase 3 | Completed | - | United States, Nevada ... More >> Mike O'Callaghan Federal Medical Center Nellis Air Force Base, Nevada, United States, 89191 Less << |
| NCT01374269 | Back Pain Lower Back | Phase 4 | Completed | - | Colombia ... More >> Clínica de Las Américas Medellin, Antioquia, Colombia Ips Universitaria Medellin, Antioquia, Colombia Less << |
| NCT01112553 | - | Terminated(Study was closed du... More >>e to low enrollment numbers.) Less << | - | United States, Massachusetts ... More >> Neuroimaging Center, McLean Hospital Belmont, Massachusetts, United States, 02478 Less << | |
| NCT01688193 | - | Completed | - | Korea, Republic of ... More >> Seoul University Hospital Seoul, Korea, Republic of Less << | |
| NCT01688934 | Osteoarthritis, Knee ... More >> Pain Less << | Phase 2 | Completed | - | United States, Arizona ... More >> Genova Clinical Research, Inc. Tucson, Arizona, United States, 85704 United States, Florida Orthopedic Research Institute Boynton Beach, Florida, United States, 33472 Avail Clinical Research, LLC Deland, Florida, United States, 32720 Westside Center for Clinical Research Jacksonville, Florida, United States, 32205 Jacksonville Center for Clinical Research Jacksonville, Florida, United States, 32216 Health Awareness, Inc. Jupiter, Florida, United States, 33458 Compass Research, LLC Orlando, Florida, United States, 32806 Compass Research East, LLC Oviedo, Florida, United States, 32765 United States, Indiana Northwest Indiana Center for Clinical Research Valparaiso, Indiana, United States, 46383 United States, Massachusetts Analgesic Solutions Natick, Massachusetts, United States, 01760 United States, Michigan Great Lakes Research Group, Inc. Bay City, Michigan, United States, 48706 United States, North Carolina PMG Research of Charlotte, LLC. Charlotte, North Carolina, United States, 28209 PMG Research of Raleigh, LLC Raleigh, North Carolina, United States, 27609 Wake Research Associates, LLC Raleigh, North Carolina, United States, 27612 United States, Oklahoma LION Research Norman, Oklahoma, United States, 73069 United States, Pennsylvania Altoona Center for Clinical Research Duncansville, Pennsylvania, United States, 16635 Clinical Research Center of Reading, LLP Wyomissing, Pennsylvania, United States, 19610 United States, Tennessee PMG Research of Bristol Bristol, Tennessee, United States, 37620 Less << |
| NCT01154790 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of Less << |
| NCT02847702 | Osteoarthritis Pain of the Kne... More >>e Less << | Phase 2 | Terminated(Company decision) | - | - |
| NCT02604550 | Anterior Cruciate Ligament Rec... More >>onstruction Less << | Phase 4 | Completed | - | United States, Georgia ... More >> Emory Healthcare Orthopaedics and Spine Center Atlanta, Georgia, United States, 30329 Less << |
| NCT01178203 | Pulpitis Pain... More >> Management Less << | Phase 1 Phase 2 | Completed | - | - |
| NCT02604550 | - | Completed | - | - | |
| NCT02500641 | Gout | Phase 4 | Completed | - | Germany ... More >> Dresden, Germany Italy Avezzano, Italy Bologna, Italy Brescia, Italy Chieti, Italy Coppito, Italy Netherlands Reade Amsterdam, Netherlands Poland Gdansk, Poland Grudziadz, Poland Katowice, Poland Krakow, Poland Lodz, Poland Warsaw, Poland Zgierz, Poland Romania Bucharest, Romania Craiova, Romania Timisoara, Romania Serbia Belgrade, Serbia Less << |
| NCT00433732 | Migraine Headaches | Phase 3 | Completed | - | United States, Arkansas ... More >> Little Rock Family Practice Clinic Little Rock, Arkansas, United States, 72205 United States, North Carolina Pozen, Inc. Chapel Hill, North Carolina, United States, 27517 Less << |
| NCT00981357 | Osteoarthritis, Knee | Phase 2 | Completed | - | United States, Florida ... More >> Arthritis & Rheumatic Care Center Miami, Florida, United States, 33143 Miami Research Associates Miami, Florida, United States, 33143 United States, Kansas Vince and Associates Clinical Research Overland Park, Kansas, United States, 66211 Vince and Associates Clinical Research Overland Park, Kansas, United States, 66212 United States, Texas CEDRA Clinical Research, LLC San Antonio, Texas, United States, 78217 Canada, Quebec Diex Research Inc. Sherbrooke, Quebec, Canada, J1H 1Z1 Sweden Centrum for klinisk provning Goteborg, Sweden, 405 30 Less << |
| NCT00837044 | Migraine Headache ... More >> Cognitive Impairment Less << | Not Applicable | Unknown | September 2009 | United States, Vermont ... More >> The Neurological Research center, Inc Recruiting Bennington, Vermont, United States, 05201` Principal Investigator: Keith R Edwards, MD Less << |
| NCT00114049 | Dental Pain S... More >>urgery, Dental Less << | Phase 3 | Completed | - | United States, Texas ... More >> GSK Investigational Site Austin, Texas, United States, 78703 Less << |
| NCT02202512 | Healthy | Phase 1 | Completed | - | Germany ... More >> 1333.43.1 Boehringer Ingelheim Investigational Site Berlin, Germany Less << |
| NCT01374269 | - | Completed | - | - | |
| NCT00602901 | Subacute Low Back Pain ... More >> Chronic Low Back Pain Less << | Phase 2 | Completed | - | United States, Iowa ... More >> Palmer Center for Chiropractic Research Davenport, Iowa, United States, 52803 The University of Iowa Iowa City, Iowa, United States, 52242 Less << |
| NCT00418782 | Osteoarthritis | Phase 2 | Terminated(Results of interim ... More >>analysis indicate lack of efficacy when compared to placebo.) Less << | - | - |
| NCT03028870 | Osteo Arthritis Knee | Phase 2 | Completed | - | - |
| NCT02355236 | Osteoarthritis | Phase 4 | Unknown | December 2015 | Korea, Republic of ... More >> Hallym University Medical Center Not yet recruiting Anyang-si, Korea, Republic of Principal Investigator: Moon-Soo Park, M.D. Inje University Ilsan Paik Hospital Not yet recruiting Goyang-si, Korea, Republic of Principal Investigator: Jin-Hwan Kim, M.D. Seoul National University Bundang Hospital Not yet recruiting Seongnam-si, Korea, Republic of Principal Investigator: Ho-Joong Kim, M.D. Asan Medical Center Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Ho-Seong Lee, M.D. Ewha Womans University Medical Center Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Sang-Jin Shin, M.D. Gangnam Severance Hospital Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Woo-Suk Lee, M.D. Hanyang University Seoul Hospital Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Chang-Nam Kang, M.D. Seoul National University Hospital Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Sang-Hoon Lee, M.D. Seoul St. Mary's Hospital Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Young-Hoon Kim, M.D. Severance Hospital Recruiting Seoul, Korea, Republic of Principal Investigator: Seong-Hwan Moon, M.D. Less << |
| NCT03028870 | - | Completed | - | - | |
| NCT02665286 | Low Back Pain | Phase 4 | Completed | - | United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less << |
| NCT01207115 | Osteoarthritis of the Knee | Phase 2 | Completed | - | - |
| NCT02665286 | - | Completed | - | - | |
| NCT00626275 | Rheumatoid Arthritis | Phase 2 | Completed | - | United States, Connecticut ... More >> New England Research Associates Trumbull, Connecticut, United States, 06611 United States, Florida Covance Clinical Research Unit Inc. Daytona Beach, Florida, United States, 32117 United States, Maryland The Center for Rheumatology and Bone Research Wheaton, Maryland, United States, 20901 United States, Nebraska Heartland Clinical Research, Inc. Omaha, Nebraska, United States, 68134 United States, Nevada Advanced Biomedical Research of America Las Vegas, Nevada, United States, 89123 United States, New York Winthrop University Hospital, Clinical Trials Center Mineola, New York, United States, 11501 United States, Ohio University Hospitals Case Medical Center, Division of Rheumatology, Rheumatology Clinical Research Unit Beachwood, Ohio, United States, 44122 United States, Pennsylvania Altoona Center for Clinical Research Duncansville, Pennsylvania, United States, 16635-8406 Less << |
| NCT02986334 | Chronic Low Back Pain | Phase 4 | Unknown | September 2018 | United States, Illinois ... More >> Northwestern University Feinberg School of Medicine Recruiting Chicago, Illinois, United States, 60611 Contact: Taha B Abdullah, M.S. 312-451-8468 taha.abdullah1@northwestern.edu Less << |
| NCT00594854 | - | Terminated(POZEN agreed with F... More >>DA to stop study due to low and inadequate enrollment) Less << | - | - | |
| NCT00626275 | - | Completed | - | - | |
| NCT02712957 | Pain Osteoart... More >>hritis of the Knee Less << | Phase 2 | Completed | - | Canada, Quebec ... More >> Diex Recherche Montreal Inc Montreal, Quebec, Canada, H2Y 1S1 Algorithme Pharma Montreal, Quebec, Canada, H3P 3P1 Diex Recherche Sherbrooke Inc Sherbrooke, Quebec, Canada, J1H 1Z1 Less << |
| NCT00442221 | Migraine Headaches | Phase 3 | Completed | - | United States, North Carolina ... More >> POZEN Inc. Chapel Hill, North Carolina, United States, 27517 Headache Wellness Center Greensboro, North Carolina, United States, 27401 Less << |
| NCT00676442 | Arthritis | Phase 1 | Completed | - | United States, Texas ... More >> Austin, Texas, United States Less << |
| NCT02646124 | Low Back Pain | Phase 2 Phase 3 | Completed | - | United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less << |
| NCT02646124 | - | Completed | - | - | |
| NCT00392080 | Osteoarthritis | Phase 1 | Completed | - | United States, California ... More >> Pfizer Investigational Site Anaheim, California, United States, 92801 Pfizer Investigational Site San Diego, California, United States, 92103-6204 United States, Florida Pfizer Investigational Site Jupiter, Florida, United States, 33458 Pfizer Investigational Site Ocoee, Florida, United States, 34761 Pfizer Investigational Site South Miami, Florida, United States, 33143 United States, New York Pfizer Investigational Site New York, New York, United States, 10021 United States, North Carolina Pfizer Investigational Site Raleigh, North Carolina, United States, 27607 Pfizer Investigational Site Raleigh, North Carolina, United States, 27612 United States, Texas Pfizer Investigational Site Houston, Texas, United States, 77074 Pfizer Investigational Site Houston, Texas, United States, 77090 United States, Virginia Pfizer Investigational Site Chesapeake, Virginia, United States, 23320 Less << |
| NCT00007189 | Alzheimer Disease | Phase 3 | Completed | - | United States, Arizona ... More >> Sun Health Research Institute Sun City, Arizona, United States, 85351 United States, Florida Roskamp Institute Memory Clinic, 10770 N. 46th Street Tampa, Florida, United States, 33617 United States, Maryland Johns Hopkins University Baltimore, Maryland, United States, 21287 United States, Massachusetts Boston University School of Medicine Boston, Massachusetts, United States, 02118 United States, New York University of Rochester Rochester, New York, United States, 14620 United States, Washington Veterans Affairs Puget Sound Health Care System, University of Washington Seattle, Washington, United States, 98108 Less << |
| NCT00945178 | Healthy Volunteers | Phase 1 | Terminated(The study was termi... More >>nated due to results in another study (NCT00878501).) Less << | - | United Kingdom ... More >> Research Site Harrow, United Kingdom Less << |
| NCT00594854 | Gastric Ulcer | Phase 3 | Terminated(POZEN agreed with F... More >>DA to stop study due to low and inadequate enrollment) Less << | - | United States, North Carolina ... More >> POZEN Chapel Hill, North Carolina, United States, 27517 Less << |
| NCT03570554 | Osteoarthritis, Knee | Phase 2 | Recruiting | March 24, 2019 | United States, Arizona ... More >> Radiant Research, Inc. Recruiting Chandler, Arizona, United States, 85224 United States, Florida Radiant Research, Inc. Recruiting Pinellas Park, Florida, United States, 33781 United States, Illinois Radiant Research, Inc. Recruiting Chicago, Illinois, United States, 60602 United States, Ohio Radiant Research, Inc. Recruiting Cincinnati, Ohio, United States, 45236 United States, Texas Radiant Research, Inc. Recruiting San Antonio, Texas, United States, 78229 Less << |
| NCT02484170 | Neuralgia, Postherpetic | Phase 1 Phase 2 | Completed | - | Canada, British Columbia ... More >> Dr. Helene Bertrand Inc. North Vancouver, British Columbia, Canada, V7M 2K2 Less << |
| NCT00819585 | Gout | Phase 2 | Completed | - | - |
| NCT00034853 | Arthritis, Juvenile Rheumatoid | Phase 3 | Completed | - | - |
| NCT02116790 | Acute Pain | Phase 2 | Withdrawn | January 2015 | - |
| NCT03084536 | Breast Cancer ... More >> Breast Cancer Female Cancer of Breast Less << | Phase 2 | Recruiting | June 30, 2020 | United States, Missouri ... More >> Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Ryan C Guffey, M.D. 314-286-2883 rguffey@wustl.edu Principal Investigator: Ryan C Guffey, M.D. Sub-Investigator: Mitchell E Fingerman, M.D. Sub-Investigator: Erin Gibbons, M.D. Sub-Investigator: Susan Ironstone, M.D. Sub-Investigator: Arbi Ben Abdallah Sub-Investigator: Rebecca L Aft, M.D. Sub-Investigator: Amy E Cyr, M.D. Sub-Investigator: Julie A Margenthaler, M.D. Sub-Investigator: Simon Haroutounian, Ph.D., MSC Sub-Investigator: Michael S Avidan, MBBCH Less << |
| NCT00819585 | - | Completed | - | - | |
| NCT03651804 | Vertebral Compression Fracture... More >> Facet Joint Pain Less << | Phase 4 | Recruiting | October 1, 2019 | United States, California ... More >> UC Davis Medical Center Recruiting Davis, California, United States, 95817 Contact: Jaimish Gwalani, MD 510-386-7942 jgwalani@ucdavis.edu Contact: Christopher Migdal, BS 4156728991 cwmigdal@ucdavis.edu Less << |
| NCT01760954 | - | Completed | - | - | |
| NCT01760954 | Endometriosis | Phase 3 | Completed | - | - |
| NCT04145518 | Dysmenorrhea (Disorder)|Dysmen... More >>orrhea Primary|Dysmenorrhea Secondary|Endometrial Diseases|Leiomyoma|Fibroid Uterus Less << | PHASE4 | RECRUITING | 2024-09-01 | NorthShore University HealthSy... More >>stem, Evanston, Illinois, 60201, United States Less << |
| Bio Calculators | ||||
| Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
|
1 mM 5 mM 10 mM |
3.96mL 0.79mL 0.40mL |
19.82mL 3.96mL 1.98mL |
39.64mL 7.93mL 3.96mL |
|
| Dissolving Methods |
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:
in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
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