Home Cart Sign in  
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 26159-34-2 Chemical Structure| 26159-34-2

Structure of Naproxen Sodium
CAS No.: 26159-34-2

Chemical Structure| 26159-34-2

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

Naproxen is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.

Synonyms: RS-3650

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

DE Stock

US Stock

Asia Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of Naproxen Sodium

CAS No. :26159-34-2
Formula : C14H13NaO3
M.W : 252.24
SMILES Code : O=C([C@H](C1=CC2=CC=C(OC)C=C2C=C1)C)[O-].[Na+]
Synonyms :
RS-3650
MDL No. :MFCD00058507
InChI Key :CDBRNDSHEYLDJV-FVGYRXGTSA-M
Pubchem ID :23681059

Safety of Naproxen Sodium

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H360
Precautionary Statements:P201-P280-P301+P312+P330-P308+P313
Class:6.1
UN#:2811
Packing Group:

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
human Th17 cells 1–10 μM 48–72 h Evaluate inhibition of IL-17 release; Naproxen showed no activity in this assay Arthritis Res Ther. 2018 Mar 1;20(1):39.
human dendritic cells 1–30 μM 24 h Evaluate inhibition of IL-23 release; Naproxen inhibited ~50% IL-23 release at 10 μM Arthritis Res Ther. 2018 Mar 1;20(1):39.
CFSC-8B rat hepatic stellate cells 0 to 10 μM 16-18 h To investigate the effect of Naproxen on VEGF and HGF expression, it was found that Naproxen significantly increased the expression of VEGF and HGF, especially under hypoxic conditions. Gastroenterology. 2009 Jun;136(7):2356-64.
Tendon-derived stromal cells 10 μM 24 h To investigate the effect of Naproxen on prostaglandin production induced by IL-1β, results showed that Naproxen significantly inhibited the production of 6-keto PGF1α and PGE2. Arthritis Res Ther. 2019 Mar 13;21(1):74.

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
DBA/1 mice Collagen-induced arthritis model Oral 60 mg/kg Once daily for 10 days Assess effects on arthritis clinical score and edema; Naproxen was ineffective in this model Arthritis Res Ther. 2018 Mar 1;20(1):39.
Mice Kras G12V mutant mice Diet 400 ppm 30 weeks To investigate the effects of Naproxen on spontaneous lung adenocarcinoma formation in Kras G12V mice. Results showed that Naproxen significantly inhibited lung tumor formation and reduced the incidence of adenocarcinoma. Neoplasia. 2021 Jun;23(6):574-583
Male Wistar rats Wistar rats Oral 38.91 mg/kg and 65.78 mg/kg Once daily for 14 days To investigate the effects of Naproxen on oxidative stress, hepatotoxicity, and genotoxicity in male Wistar rats. Results showed that NP treatment decreased GSH levels and increased SOD, CAT, LPO, ALT, AST, ALP, and TBIL activities/levels. MNT results showed increased micronucleus induction, and the comet assay showed a significant increase in DNA damage. J Pharm Anal. 2018 Dec;8(6):400-406
Female Lewis rats Collagen-induced arthritis (CIA) model Oral gavage 8 mg/kg Daily administration for 44 days To evaluate the effects of Naproxen monotherapy and its combination with KBP on health scores, pain assessments, and bone structure in the CIA rat model. Results showed that Naproxen monotherapy increased the time until humane endpoints were reached, improved health scores, pain assessments, and trabecular thickness, while combination therapy further enhanced efficacy, improved health scores, reduced mechanical and cold allodynia, and protected articular cartilage structure and bone volume. Arthritis Res Ther. 2019 Feb 22;21(1):68
Rat Inflammatory Soup Migraine Model Tail vein injection 1mg/kg Single injection, lasting two minutes To investigate the effects of Sumatriptan/Naproxen on brain networks in a migraine model in rats, the results showed that the combination significantly altered functional connectivity across several brain networks, including the cerebellar, default mode, basal ganglia, autonomic, and salience networks. Pain. 2019 Sep;160(9):2161-2171
Mice Lynch syndrome mouse model Dietary administration 166 ppm Continuous administration Naproxen significantly reduced tumor burden and prolonged survival, and the effect was even more pronounced when combined with FSP vaccination. Gastroenterology. 2021 Oct;161(4):1288-1302.e13
Rat DPPIV-F344 rats Intraperitoneal injection 2, 4, 6 mg/kg Single dose, or 8 doses over 3 days after cell transplantation To investigate the effect of Naproxen on hepatocyte engraftment after transplantation, it was found that Naproxen significantly improved the engraftment of transplanted hepatocytes. Gastroenterology. 2009 Jun;136(7):2356-64.

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00875784 Migraine Disorders Phase 1 Completed - United States, Washington ... More >> GSK Investigational Site Tacoma, Washington, United States, 98418 Less <<
NCT01994226 Gout Phase 4 Completed - United Kingdom ... More >> Keele University Stoke-on-Trent, United Kingdom Less <<
NCT03448536 Dysmenorrhea Phase 4 Completed - United States, Arizona ... More >> Radiant Research, Inc. Chandler, Arizona, United States, 85224 Radiant Research, Inc. Scottsdale, Arizona, United States, 85251 United States, Florida Radiant Research, Inc. Pinellas Park, Florida, United States, 33781 United States, Illinois Radiant Research, Inc. Chicago, Illinois, United States, 60602 United States, Ohio Radiant Research, Inc. Akron, Ohio, United States, 44311 Radiant Research, Inc. Cincinnati, Ohio, United States, 45236 United States, Texas Radiant Research, Inc. Dallas, Texas, United States, 75234 Synexus US, LP- Plano Plano, Texas, United States, 75234 Less <<
NCT02786446 Renal Stone Not Applicable Completed - -
NCT01994226 - Completed - -
NCT00959439 Rheumatoid Arthritis ... More >> Osteoarthritis Less << Phase 1 Completed - -
NCT03658473 Gastric Lesion Phase 3 Completed - Brazil ... More >> Galeno Desenvolvimento de Pesquisas Clinicas Ltda. Campinas, SP, Brazil, 13087-010 Less <<
NCT03347929 Sciatica Phase 4 Recruiting November 2021 Norway ... More >> Seksjon for fysikalsk medisin og rehabilitering, Drammen Sykehus, Vestre Viken Recruiting Drammen, Norway, 3004 Contact: Anne Froholdt, MD,PhD          Revmatologisk avdeling, Sykehuset Østfold Moss Recruiting Moss, Norway, 1714 Contact: Anne J Haugen, MD,PhD    +4791193452    annhau@so-hf.no    Fysikalsk medisinsk poliklinikk, Sykehuset Telemark Recruiting Porsgrunn, Norway, 3710 Contact: Anders Sætre, MD          Avdeling for fysikalsk medisin og rehabilitering, Stavanger Universitetssjukehus Recruiting Stavanger, Norway, 4068 Contact: Ståle Mathiassen, MD Less <<
NCT00761501 Healthy Volunteer Phase 1 Completed - Sweden ... More >> Research Site Lulea, Sweden Research Site Uppsala, Sweden Less <<
NCT00804401 Bioequivalency Phase 1 Completed - -
NCT01165814 Pain Cesarean... More >> Section Less << Not Applicable Completed - Israel ... More >> Bnai Zion Medical Center Haifa, Israel Less <<
NCT01427803 Pain Phase 3 Completed - -
NCT00803764 Bioequivalency Phase 1 Completed - -
NCT01612975 Pleural Effusion ... More >> Pleural Effusion Malignant Less << Phase 2 Terminated(Recruitment futile) - Canada, Ontario ... More >> St. Joseph's Healthcare Hamilton Hamilton, Ontario, Canada, L8N 4A6 Less <<
NCT00807846 Arthritis, Juvenile Rheumatoid Phase 4 Completed - -
NCT01427803 - Completed - -
NCT00807846 - Completed - -
NCT00329459 Migraine Disorders Phase 3 Completed - -
NCT02519231 Menorrhagia Phase 4 Completed - United States, Illinois ... More >> John H Stroger Jr Hospital of Cook County Chicago, Illinois, United States, 60612 United States, Washington Harborview Medical Center Seattle, Washington, United States, 98104 UW Neighborhood Clinic Northgate Seattle, Washington, United States, 98125 Hall Health Center Seattle, Washington, United States, 98195 University of Washington Medical Centers Seattle, Washington, United States, 98195 Less <<
NCT00662896 Osteoarthritis ... More >> Hypertension Less << Phase 1 Completed - -
NCT02632812 - Completed - -
NCT02632812 Gastrointestinal Lesions Phase 1 Completed - -
NCT01525043 Epicondylitis of the Elbow Phase 4 Completed - United States, Kansas ... More >> International Clinical Research Institute Overland Park, Kansas, United States, 66210 Less <<
NCT03161093 Osteoarthritis, Knee ... More >> Osteoarthritis, Hip Less << Phase 3 Recruiting April 5, 2021 -
NCT02255955 Postoperative Pain ... More >> Postoperative Laminectomy Pain Less << Phase 4 Unknown December 2014 -
NCT01090596 Healthy Not Applicable Completed - -
NCT00222976 Post-Vaginal Delivery Perineal... More >> Pain Less << Phase 4 Completed - Canada, Saskatchewan ... More >> Department of Anesthesia, Royal University Hospital, University of Saskatchewan Saskatoon, Saskatchewan, Canada, S7N 0W8 Less <<
NCT00383487 Prostatic Neoplasms ... More >> Prostate Cancer Less << Phase 2 Terminated(Extreme toxicity) - United States, California ... More >> Stanford University School of Medicine Stanford, California, United States, 94305 Less <<
NCT00503828 Knee Osteoarthritis Phase 3 Completed - Thailand ... More >> Siriraj Hospital Bangkoknoi, Bangkok, Thailand, 10700 Less <<
NCT01090050 Chronic Migraine Phase 4 Completed - United States, Missouri ... More >> Clinvest Springfield, Missouri, United States, 65807 United States, Texas Texas Headache Associates San Antonio, Texas, United States, 78258 Less <<
NCT00449787 - Completed - -
NCT00385008 Migraine Disorders Phase 3 Completed - United States, Kentucky ... More >> GSK Investigational Site Lexington, Kentucky, United States, 40503 Less <<
NCT00449787 Migraine Tens... More >>ion-type Headache Primary Headache Disorder Less << Phase 4 Completed - United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Columbia University Medical Center New York, New York, United States, 10032 Less <<
NCT00385008 - Completed - -
NCT00615875 Pain, Postoperative Phase 4 Unknown June 2008 Canada, Ontario ... More >> St. Joseph's Healthcare Hamilton Not yet recruiting Hamilton, Ontario, Canada, L8N 4A6 Principal Investigator: Victoria Luckham, BScPhm Less <<
NCT00893594 Migraine With Aura Not Applicable Unknown December 2015 United States, New York ... More >> Dent Neurologic Institute Recruiting Amherst, New York, United States, 14226 Contact: Rebecca M Hogan, BS    716-558-5670    rhogan@dentinstitute.com    Contact: Mary K Betz, P.A.    716-558-5662    mbetz@dentinstitute.com    Principal Investigator: Laszlo L Mechtler, M.D. Less <<
NCT01090050 - Completed - -
NCT00790985 Osteoarthritis Not Applicable Completed - -
NCT00907400 Healthy Phase 1 Completed - Sweden ... More >> Research Site Lulea, Sweden Research Site Uppsala, Sweden Less <<
NCT01409603 Pharmacodynamic Interaction ... More >> Healthy Subjects Less << Phase 1 Completed - France ... More >> SGS Aster Paris, France, 75015 Less <<
NCT00843024 Migraine Disorders Phase 3 Completed - -
NCT00843024 - Completed - -
NCT00665743 Arthritis Phase 1 Completed - United States, Texas ... More >> Austin, Texas, United States Less <<
NCT01450995 Migraine Phase 4 Completed - United States, Tennessee ... More >> Wesley Headache Clinic Memphis, Tennessee, United States, 38018 Less <<
NCT00153660 Arthritis Car... More >>diovascular Diseases Cerebrovascular Disorders Less << Phase 3 Completed - China, Hong Kong ... More >> Endoscopy Center, Prince of Wales Hospital Shatin, Hong Kong, China Less <<
NCT00692016 Bioavailability Phase 1 Completed - United States, Arkansas ... More >> Little Rock, Arkansas, United States, 72202 Less <<
NCT03167541 Healthy Phase 1 Completed - -
NCT01381497 - Completed - -
NCT01390324 Migraine Head... More >>ache Less << Phase 3 Withdrawn - -
NCT01063920 Osteoarthritis Phase 2 Phase 3 Completed - -
NCT00240630 Migraine Disorders ... More >> Migraine Less << Phase 3 Completed - -
NCT02183038 Pharyngitis Phase 2 Completed - -
NCT00692055 Arthritis Phase 1 Completed - United States, Texas ... More >> Austin, Texas, United States Less <<
NCT00596245 Healthy Phase 1 Completed - United States, Texas ... More >> Matthew M. Medlock, MD Austin, Texas, United States, 78744 Less <<
NCT02769247 - Completed - -
NCT02769247 Contraception ... More >> Pain Less << Not Applicable Completed - United States, Maryland ... More >> Walter Reed National Military Medical Center Bethesda, Maryland, United States, 20889 Less <<
NCT01995006 Healthy Phase 1 Completed - Switzerland ... More >> Phase I Research Unit, University Hospital Basel, Switzerland Less <<
NCT00751556 Healthy Phase 1 Completed - United States, Arkansas ... More >> Little Rock, Arkansas, United States, 72202 Less <<
NCT02463552 Toothache Too... More >>th Bleaching Less << Not Applicable Completed - Brazil ... More >> Universidade Federal de Sergipe Aracaju, SE, Brazil, 49060100 Less <<
NCT00928837 Osteoarthritis Not Applicable Completed - United States, Pennsylvania ... More >> Alan Kivitz MD Duncansville, Pennsylvania, United States, 16635 Less <<
NCT00789802 - Completed - -
NCT00789802 Contraception ... More >> Bleeding Less << Not Applicable Completed - United States, Missouri ... More >> Washington University School fo Medicine Saint Louis, Missouri, United States, 63110 Less <<
NCT01118273 Sleep Phase 4 Completed - United States, Utah ... More >> Salt Lake City, Utah, United States, 84124 Less <<
NCT01666678 Therapeutic Equivalence Phase 1 Completed - United States, New Jersey ... More >> Hackensack, New Jersey, United States, 07601 Less <<
NCT00749385 Arthritis Phase 1 Completed - United States, Texas ... More >> PPD Austin, Texas, United States, 78744 Less <<
NCT02501564 Osteoarthritis Phase 4 Completed - -
NCT00751400 Pain Phase 3 Completed - United States, California ... More >> Anaheim, California, United States, 92801 Oceanside, California, United States, 92054 San Dimas, California, United States, 91773 United States, Kansas Overland Park, Kansas, United States, 66209 United States, Minnesota Anoka, Minnesota, United States, 55303 Blaine, Minnesota, United States, 55443 Elk River, Minnesota, United States, 55330 St. Francis, Minnesota, United States, 55070 St. Louis Park, Minnesota, United States, 55426 United States, Missouri Belton, Missouri, United States, 64012 Savannah, Missouri, United States, 64485 St. Joseph, Missouri, United States, 64504 United States, North Carolina Cary, North Carolina, United States, 27513 Chapel Hill, North Carolina, United States, 27514 Raleigh, North Carolina, United States, 27606 Raleigh, North Carolina, United States, 27612 United States, Utah Bountiful, Utah, United States, 84010 Ogden, Utah, United States, 84401 Salt Lake City, Utah, United States, 84102 Syracuse, Utah, United States, 84075 West Jordan, Utah, United States, 84088 United States, Washington Kenmore, Washington, United States, 98028 Seattle, Washington, United States, 98148 Snohomish, Washington, United States, 98290 Less <<
NCT01118273 - Completed - -
NCT01726920 Migraine Head... More >>ache Less << Phase 3 Withdrawn(Due to budget limita... More >>tions, the company decided to withdraw this study.) Less << - -
NCT02549469 Pain Phase 1 Completed - -
NCT00662610 Osteoarthritis ... More >> Hypertension Less << Phase 1 Completed - -
NCT00992381 Healthy Phase 1 Completed - Australia, Queensland ... More >> Research Site Brisbane, Queensland, Australia Less <<
NCT01300546 - Completed - -
NCT01300546 Migraine Phase 4 Completed - United States, California ... More >> Newport Beach Clinical Research Assoc., Inc. Newport Beach, California, United States, 92663 United States, Missouri Clinvest Springfield, Missouri, United States, 65807 Less <<
NCT00751400 - Completed - -
NCT00601458 - Completed - -
NCT01381523 - Completed - -
NCT00527787 Gastric Ulcer Phase 3 Completed - United States, North Carolina ... More >> POZEN Chapel Hill, North Carolina, United States, 27517 Less <<
NCT00382993 Migraine Disorders Phase 3 Completed - -
NCT00382993 - Completed - -
NCT00383162 Migraine Disorders Phase 3 Completed - -
NCT01129011 Gastric Ulcer Phase 3 Completed - -
NCT01129011 - Completed - -
NCT03404206 Pain, Postoperative Phase 4 Completed - United States, Utah ... More >> Jean Brown Research Salt Lake City, Utah, United States, 84124 Less <<
NCT01365052 Pain Phase 3 Completed - United States, Arizona ... More >> Chandler, Arizona, United States, 85224 Mesa, Arizona, United States, 85203 Peoria, Arizona, United States, 85381 United States, California Anaheim, California, United States, 92801 Rancho Cucamonga, California, United States, 91730 Sacramento, California, United States, 95816 United States, Colorado Colorado Springs, Colorado, United States, 80922 United States, Florida Kissimmee, Florida, United States, 34741 Pembroke Pines, Florida, United States, 33028 South Miami, Florida, United States, 33143 United States, Georgia Stockbridge, Georgia, United States, 30281 United States, Louisiana Metairie, Louisiana, United States, 70006 United States, Maryland Elkridge, Maryland, United States, 21075 United States, Rhode Island Warwick, Rhode Island, United States, 02886 United States, South Carolina Mt. Pleasant, South Carolina, United States, 29464 United States, Texas Fort Worth, Texas, United States, 76135 San Angelo, Texas, United States, 76904 San Antonio, Texas, United States, 78231 United States, Utah Salt Lake City, Utah, United States, 84106 Less <<
NCT00527787 - Completed - -
NCT02052908 Lynch Syndrome Phase 1 Active, not recruiting - United States, Massachusetts ... More >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 United States, Michigan University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan, United States, 48109 United States, Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 United States, Utah Huntsman Cancer Institute/University of Utah Salt Lake City, Utah, United States, 84112 Less <<
NCT01365052 - Completed - -
NCT02351024 Pharmacokinetics Phase 1 Completed - United Kingdom ... More >> Quotient Clinical Ltd Nottingham, United Kingdom Less <<
NCT03424135 Pain Phase 1 Completed - United States, Texas ... More >> ICON Development Solutions, LLC San Antonio, Texas, United States, 78219 Less <<
NCT00966641 Healthy Volunteers Phase 1 Phase 2 Completed - United States, Texas ... More >> Houston Institute for Clinical Research Houston, Texas, United States, 77074 Less <<
NCT00601458 Acute Pain Phase 1 Completed - -
NCT03396250 Pain Phase 1 Completed - United States, Texas ... More >> ICON Development Solutions, LLC San Antonio, Texas, United States, 78219 Less <<
NCT00966641 - Completed - -
NCT01280591 Pain, Postoperative Phase 3 Completed - United States, Texas ... More >> Austin, Texas, United States, 78744 United States, Utah Salt Lake City, Utah, United States, 84124 Less <<
NCT01280591 - Completed - -
NCT00720057 - Completed - -
NCT00586365 Heterotopic Ossification Phase 4 Withdrawn(Too difficult to sat... More >>isfy all the inclusion criteria.) Less << - United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Less <<
NCT00720057 Toothache Phase 3 Completed - United States, Texas ... More >> Austin, Texas, United States, 78705 Austin, Texas, United States, 78744 United States, Utah Salt Lake City, Utah, United States, 84124 Less <<
NCT02229461 - Completed - -
NCT02229461 Hematology Phase 1 Completed - United States, Texas ... More >> Austin, Texas, United States, 78744 Less <<
NCT00383162 - Completed - -
NCT02388191 Contraception Not Applicable Completed - United States, Massachusetts ... More >> Planned Parenthood League of Massachusetts Boston, Massachusetts, United States, 02215 Less <<
NCT02702817 Alzheimer Disease ... More >> Cognitive Decline Due to Alzheimer Disease Mild Cognitive Impairment Due to Alzheimer Disease Less << Phase 2 Completed - Canada, Quebec ... More >> Douglas Hospital Research Centre Montreal, Quebec, Canada, H4H1R3 Less <<
NCT01539447 Heterotopic Ossification Early Phase 1 Active, not recruiting January 2019 United States, Utah ... More >> University of Utah Orthopedics Center Salt Lake City, Utah, United States, 84108 Less <<
NCT00818415 Pain Phase 1 Completed - United States, Texas ... More >> Austin, Texas, United States, 78744 Less <<
NCT01557816 Osteoarthritis, Knee Not Applicable Unknown June 2012 United States, Massachusetts ... More >> Analgesic Solutions Recruiting Natick, Massachusetts, United States, 01760 Contact: Stephen Wright, MD    781-444-9605 ext 101    swright@analgesicsolutions.com    Contact: Pura Requintina, Ph.D.    781-444-9605 ext 121    prequintina@analgesicsolutions.com    Principal Investigator: Stephen Wright, MD Less <<
NCT02388191 - Completed - -
NCT02494856 Pain Other Su... More >>rgical Procedures Impacted Third Molar Tooth Less << Phase 4 Completed - Brazil ... More >> University of São Paulo Bauru, SP, Brazil, 17012-901 Less <<
NCT00792636 Migraine Disorders Phase 4 Completed - -
NCT03566979 Post-operative Dental Pain Phase 3 Recruiting May 10, 2019 United States, Utah ... More >> JBR Clinical Research Recruiting Salt Lake City, Utah, United States, 84124 Less <<
NCT01495858 Pain, Postoperative Phase 3 Completed - United States, Texas ... More >> Austin, Texas, United States, 78744 United States, Utah Salt Lake City, Utah, United States, 84106 Less <<
NCT01495858 - Completed - -
NCT00792636 - Completed - -
NCT01389284 Pain, Postoperative Phase 3 Completed - United States, Texas ... More >> Austin, Texas, United States, 78744 Less <<
NCT00488514 Migraine Disorders Phase 3 Completed - -
NCT01389284 - Completed - -
NCT01952652 Arthroscopic Meniscus Surgery Phase 4 Completed - Turkey ... More >> Baskent University School of Medicine Adana Teaching and Research Hospital Adana, Turkey, 01250 Less <<
NCT03092193 Poor Metabolizer Due to Cytoch... More >>rome P450 CYP2C9 Variant Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant Less << Phase 4 Recruiting December 2018 Brazil ... More >> Bauru School of Dentistry/USP Recruiting Bauru, São Paulo, Brazil, 17012-901 Contact: Adriana M Calvo, PhD    551432358276    birinjela@yahoo.com.br Less <<
NCT01052792 Healthy PHASE1 COMPLETED 2025-06-06 Wellquest Clinical Research, M... More >>umbai, Maharashtra, 400 013, India Less <<
NCT00488514 - Completed - -
NCT01383486 - Completed - -
NCT01131728 Healthy Phase 1 Completed - India ... More >> Lotus Labs Private Limited Bangalore, Karnataka, India, 560034 Less <<
NCT01383486 Pain Phase 3 Completed - United States, California ... More >> Anaheim, California, United States, 92801 Yorba Linda, California, United States, 92886 United States, Florida Pembroke Pines, Florida, United States, 33026 United States, Georgia Griffin, Georgia, United States, 30224 United States, Minnesota Andover, Minnesota, United States, 55304 Roseville, Minnesota, United States, 55113 United States, Utah Bountiful, Utah, United States, 84010 West Jordan, Utah, United States, 84088 United States, Washington Bellevue, Washington, United States, 98007 Seattle, Washington, United States, 98122 Less <<
NCT01052129 Healthy Phase 1 Completed - India ... More >> Wellquest Clinical Research Mumbai, Maharashtra, India, 400 013 Less <<
NCT03291418 Gastric Ulcer Phase 1 Phase 2 Completed - Canada, Ontario ... More >> Topstone Clinical Research Toronto, Ontario, Canada, M9C 4Z5 Less <<
NCT01131767 Healthy Phase 1 Completed - India ... More >> Lotus Labs Private Limited Bangalore, Karnataka, India, 560034 Less <<
NCT00969449 Pharmacokinetics Phase 1 Completed - United States, Texas ... More >> Austin, Texas, United States, 78744 Less <<
NCT03697889 Healthy Phase 1 Not yet recruiting March 31, 2019 Russian Federation ... More >> LLC "Scientific and Research centre Eco-safety" Not yet recruiting St.Petersburg, Russian Federation, 196143 Less <<
NCT02143713 Endometriosis Phase 3 Completed - -
NCT01339156 Acute Dental Pain Phase 1 Terminated - -
NCT01931670 Endometriosis Phase 3 Completed - -
NCT02143713 - Completed - -
NCT01620528 Endometriosis Phase 3 Completed - -
NCT01638962 Osteoarthritis, Knee Not Applicable Completed - Denmark ... More >> University of Southern Denmark Odense, Region Syddanmark, Denmark, 5230 Less <<
NCT01620528 - Completed - -
NCT01511627 Hysterectomy Not Applicable Withdrawn(Research question wa... More >>s answered by Acta Anaesthesiol Scand 2012; 56 102-109.) Less << - Canada, Saskatchewan ... More >> Saskatoon City Hospital Saskatoon, Saskatchewan, Canada, S7K0M7 Less <<
NCT02094807 Trauma Rib Fr... More >>actures Surgery Pain Less << Not Applicable Withdrawn(Slow inclusion rate.... More >> Awaiting results from NCT02132416.) Less << May 2020 Sweden ... More >> Sahlgrenska University Hospital Gothenburg, Sweden, 413 45 Less <<
NCT02132416 Trauma Flail ... More >>Chest Rib Fractures Surgery Less << Not Applicable Active, not recruiting December 2018 Sweden ... More >> Departement of Surgery, Sahlgrenska University Hospital Gothenburg, Sweden, 413 45 Departement of Intensive Care, Karolinska University Hospital Stockholm, Sweden, 171 76 Less <<
NCT00551135 Pain, Postoperative ... More >> Hernia, Inguinal Less << Phase 3 Completed - -
NCT00285649 Low Back Pain Not Applicable Completed - United States, Iowa ... More >> Palmer Center for Chiropractic Research Davenport, Iowa, United States, 52803 Less <<
NCT02397785 - Completed - -
NCT01003639 - Completed - -
NCT01003639 Idiopathic Intracranial Hypert... More >>ension Less << Phase 2 Phase 3 Completed - -
NCT00551135 - Completed - -
NCT02397785 Pelvic Pain Not Applicable Completed - United States, Ohio ... More >> Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195 Less <<
NCT00447759 Osteoarthritis ... More >> Rheumatoid Arthritis Less << Phase 4 Completed - Denmark ... More >> University of Southern Denmark Odense, Denmark, 5000 Netherlands Julius Clinical Research Zeist, Netherlands, 3703 CD Zeist United Kingdom University of Aberdeen Aberdeen, United Kingdom, AB25 2ZN University of Birmingham Birmingham, United Kingdom, B15 2TT University of Dundee Dundee, United Kingdom, DD1 9SY University of Edinburgh Edinburgh, United Kingdom, EH4 2XU University of Glasgow Glasgow, United Kingdom, G11 6NT NHS Highlands Inverness, United Kingdom, IV2 3JH University of Nottingham Nottingham, United Kingdom, NG7 2UH University of Oxford Oxford, United Kingdom, OX1 2ET Less <<
NCT01931670 - Completed - -
NCT01916395 - Completed - United States, Michigan ... More >> Westside Family Medical Center, PC Kalamazoo, Michigan, United States, 49009 Less <<
NCT00285649 - Completed - -
NCT00621881 Liver Disease Phase 1 Completed - United States, Florida ... More >> Miami, Florida, United States Less <<
NCT02945839 Migraine Phase 4 Not yet recruiting December 2018 United States, New York ... More >> New York University School of Medicine Not yet recruiting New York, New York, United States, 10016 Contact: Liliana Serrano       Liliana.Serrano2@nyumc.org    Principal Investigator: mia Minen, MD Less <<
NCT01761864 Study Focus: Prescribing of Dr... More >>ugs Less << Not Applicable Unknown January 2016 Belgium ... More >> University of Antwerp Wilrijk, Belgium, 2610 Less <<
NCT02322996 - Withdrawn(never started) - United States, North Carolina ... More >> School of Dental Medicine At East Carolina University Greenville, North Carolina, United States, 27834 Less <<
NCT00688545 - Terminated(See termination rea... More >>son in detailed description.) Less << - -
NCT00688545 - Terminated(See termination rea... More >>son in detailed description.) Less << - -
NCT01094483 Platelet Inhibition Phase 1 Completed - United States, Kansas ... More >> Research Site Overland Park, Kansas, United States Less <<
NCT03245008 Osteoarthritis, Knee / Osteoar... More >>thritis, Hip Less << Phase 2 Phase 3 Recruiting January 2021 Japan ... More >> Investigational Site Recruiting Aichi, Japan Investigational Site Recruiting Aomori, Japan Investigational Site Recruiting Chiba, Japan Investigational Site Recruiting Ehime, Japan Investigational Site Recruiting Fukui, Japan Investigational Site Recruiting Fukuoka, Japan Investigational Site Recruiting Fukushima, Japan Investigational Site Recruiting Gunma, Japan Investigational Site Recruiting Hiroshima, Japan Investigational Site Recruiting Hokkaido, Japan Investigational Site Recruiting Hyogo, Japan Investigational Site Recruiting Ibaraki, Japan Investigational Site Recruiting Kagoshima, Japan Investigational Site Recruiting Kanagawa, Japan Investigational Site Recruiting Kumamoto, Japan Investigational Site Recruiting Kyoto, Japan Investigational Site Recruiting Mie, Japan Investigational Site Recruiting Miyagi, Japan Investigational Site Recruiting Miyazaki, Japan Investigational Site Recruiting Oita, Japan Investigational Site Recruiting Osaka, Japan Investigational Site Recruiting Saitama, Japan Investigational Site Recruiting Shiga, Japan Investigational Site Recruiting Shizuoka, Japan Investigational Site Recruiting Tokyo, Japan Investigational Site Recruiting Yamagata, Japan Investigational Site Recruiting Yamaguchi, Japan Less <<
NCT03220633 Chronic Pain Phase 1 Completed - Canada, Quebec ... More >> Algorithme Pharma Montreal, Quebec, Canada Less <<
NCT02707094 Chronic Low Back Pain Not Applicable Completed - United States, Texas ... More >> Brooke Army Medical Center Fort Sam Houston, Texas, United States, 78234 Less <<
NCT01267825 Disc Herniation ... More >> Lumbosacral Radiculopathy Less << Phase 4 Terminated(Study terminated ea... More >>rly due to low enrollment. No data collected.) Less << - United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less <<
NCT00809354 Osteoarthritis ... More >> Arthritis Less << Phase 3 Terminated(See termination rea... More >>son in detailed description.) Less << - -
NCT03031938 Osteoarthritis ... More >> Cancer Pain Recurrent Low Back Pain Less << Phase 3 Recruiting April 4, 2022 United States, California ... More >> USC Keck School of Medicine Recruiting Los Angeles, California, United States, 90033 United States, Florida Gulfcoast Research Institute Recruiting Sarasota, Florida, United States, 34232 Kennedy and White Orthopaedic Center Recruiting Sarasota, Florida, United States, 34232 Pediatric Epilepsy & Neurology Specialists Recruiting Tampa, Florida, United States, 33609 United States, Indiana Lafayette Clinical Research Group Active, not recruiting Lafayette, Indiana, United States, 47905 Preferred Pediatrics Active, not recruiting Lafayette, Indiana, United States, 47905 Less <<
NCT01267825 - Terminated(Study terminated ea... More >>rly due to low enrollment. No data collected.) Less << - -
NCT00665431 - Completed - -
NCT01298531 Axial Spondyloarthritis Phase 4 Completed - France ... More >> Institut Calot - Fondation Hopale Berck-sur-Mer, France, 62608 Hopital Pellegrin Bordeaux Cedex, France, 33076 Centre Hospitalier, Service de Rhumatologie Cahors, France, 46000 CHU Hopital Gabriel Montpied Clermont-Ferrand, France, 63003 Centre Hospitalier Sud Francilien Corbeil Essonnes, France, 91100 Hopital Bicetre LE KREMLIN-BICETRE Cedex, France, 94275 CH Le Mans Le Mans, France, 72037 Chu Dupuytren, Rhumatologie et Therapeutique Limoges, France, 87042 CHU Lapeyronie, Immuno-Rhumatologie Montpellier, France, 34000 Hopital de l'Archet Nice, France, 06202 Hopital Porte Madeleine Orleans Cedex 1, France, 45032 H�al Saint-Antoine Paris, France, 75012 Hopital Cochin Paris, France, 75014 Hopital Saint Joseph - Service de Rhumatologie Paris, France, 75014 Hopital Bichat Paris, France, 75018 Service de Rhumatologie Paris, France, 75651 Cedex 13 CHU Bois Guillaume - Service de Rhumatologie Rouen, France, 76031 CHU de Saint Etienne, Hopital Nord Saint Etienne Cedex 2, France, 42055 Hopital Purpan Toulouse Cedex 09, France, 31059 Less <<
NCT01298531 - Completed - -
NCT00664560 - Completed - -
NCT00664560 Osteoarthritis Phase 3 Completed - United States, North Carolina ... More >> POZEN Chapel Hill, North Carolina, United States, 27517 Less <<
NCT02674386 Osteoarthritis Phase 3 Recruiting August 12, 2019 -
NCT00001955 Temporomandibular Joint Disord... More >>er Less << Phase 2 Completed - United States, Maryland ... More >> National Institute of Dental And Craniofacial Research (NIDCR) Bethesda, Maryland, United States, 20892 Less <<
NCT00599404 Healthy Phase 1 Completed - -
NCT00665431 Osteoarthritis Phase 3 Completed - United States, North Carolina ... More >> POZEN Chapel Hill, North Carolina, United States, 27517 Less <<
NCT00737737 Chronic Pain ... More >>Osteoarthritis Less << Phase 4 Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT00737737 - Completed - -
NCT00065559 Diabetic Nephropathy Not Applicable Terminated - United States, Illinois ... More >> Rush Presbyterian St. Luke's Medical Center Chicago, Illinois, United States, 60612 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less <<
NCT01355549 Shoulder Pain ... More >> Rotator Cuff Tendinitis Rotator Cuff Syndrome Spinal Cord Injury Less << Phase 1 Completed - United States, New Jersey ... More >> Kessler Institute for Rehabilitation West Orange, New Jersey, United States, 07052 Less <<
NCT02771249 Healthy Volunteers Phase 1 Recruiting December 31, 2019 United States, Maryland ... More >> National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)    800-411-1222 ext TTY8664111010    prpl@cc.nih.gov Less <<
NCT01843179 Acute Myeloid Leukemia Phase 2 Withdrawn(Lack of Funding) - United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02115 Less <<
NCT02929589 Pain Hernia Phase 3 Recruiting April 2020 United States, Nevada ... More >> Mike O'Callaghan Federal Medical Center Recruiting Nellis Air Force Base, Nevada, United States, 89191 Contact: Jill M Clark, MBA/HCM    702-653-3298    jill.m.clark15.ctr@mail.mil    Principal Investigator: William Scott, DO Less <<
NCT02580344 Contraception Phase 2 Completed - Egypt ... More >> Assiut university Assiut, Egypt, 71111 Less <<
NCT02903680 Migraine Phase 1 Recruiting June 2019 Canada, Quebec ... More >> CHU Sainte Justine Recruiting Montréal, Quebec, Canada, H3T1C4 Contact: Geneviève Tourigny-Ruel    5149143133    getruel@yahoo.ca    Principal Investigator: Benoit Bailey, MD          Sub-Investigator: Jocelyn Gravel, MD Less <<
NCT01511926 - Completed - -
NCT01481103 Migraine Headache Not Applicable Terminated(PI cited personal r... More >>easons) Less << - United States, Illinois ... More >> Serenity Acupuncture and Oriental Medicine Oak Park, Illinois, United States, 60302 Less <<
NCT00543868 Stomach Ulcer ... More >> Duodenal Ulcer Less << Phase 2 Completed - -
NCT02139046 - Completed - -
NCT02128490 Gout Moderate... More >> Renal Impairment Less << Phase 2 Completed - -
NCT03472469 Nonspecific Pain Post Traumati... More >>c Injury Less << Phase 4 Enrolling by invitation October 1, 2019 United States, Texas ... More >> The University of Texas Health Science Center at Houston Houston, Texas, United States, 77030 Less <<
NCT02139046 Gout Phase 3 Completed - -
NCT01982799 Odontalgia Not Applicable Withdrawn(Not enough funding) - United States, Minnesota ... More >> University of Minnesota School of Dentistry Minneapolis, Minnesota, United States, 55455 Less <<
NCT01071317 Migraine Phase 4 Completed - United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less <<
NCT02643719 Migraine Not Applicable Withdrawn(Study team missed co... More >>ntinuing review and study lapsed with out recruiting any subjects.) Less << - -
NCT02689024 Hip Fractures ... More >> Anesthesia Less << Phase 4 Recruiting July 2019 Netherlands ... More >> Meander Medical Center Recruiting Amersfoort, Netherlands, 3813 TZ Contact: Maurice Pouw, MD    033 850 5050    me.pouw@meandermc.nl    Slotervaart Medical Center Recruiting Amsterdam, Netherlands, 1066 EC Contact: Daniel Haverkamp, MD, PhD    020 - 512 93 33    Daniël.Haverkamp@slz.nl    VU Medical Center Recruiting Amsterdam, Netherlands, 1081 HV Contact: Edwin Vandewalle, MD    0031(0)20-4444444    e.vandewalle@vumc.nl    Academic Medical Center Recruiting Amsterdam, Netherlands, 1105 AZ Contact: Milan Ridderikhof, MD    0031-(0)20-5663336    m.l.ridderikhof@amc.uva.nl    Contact: Helma Goddijn, MSc    0031-(0)20-5663336    w.m.t.goddijn@amc.uva.nl Less <<
NCT02522130 IUD Insertion Complication Not Applicable Unknown December 2016 Egypt ... More >> Menoufia University Recruiting Shebin Elkom, Egypt Contact: nabih elkholy, MD    00201060868443       Saudi Arabia Alhayah national hospital Recruiting Abha, Saudi Arabia Contact: mohamed maher    +966558198655       Contact: tarek sayyed          Principal Investigator: mohamed maher Less <<
NCT02128490 - Completed - -
NCT02293681 - Terminated(The project was sto... More >>pped by 31-May-2017 because of internal owner decision from out of balance enrollment from two groups.) Less << - China ... More >> Beijing, China Changsha, China Chengdu, China Guangzhou, China Shanghai, China Xi'An, China Xian, China Less <<
NCT01578941 Menstrual Migraine Phase 4 Completed - United States, Alabama ... More >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35233 Less <<
NCT02528188 Chronic Pain ... More >>Osteoarthritis, Hip Osteoarthritis, Knee Less << Phase 3 Active, not recruiting February 2019 -
NCT00447486 Osteoarthritis, Knee Phase 2 Completed - Denmark ... More >> GSK Investigational Site Hvidovre, Denmark, 2650 GSK Investigational Site Odense C, Denmark, 5000 Germany GSK Investigational Site Muenchen, Bayern, Germany, 80333 GSK Investigational Site Essen, Nordrhein-Westfalen, Germany, 45359 GSK Investigational Site Koeln, Nordrhein-Westfalen, Germany, 51069 GSK Investigational Site Leipzg, Sachsen, Germany, 04109 GSK Investigational Site Schmiedeberg, Sachsen, Germany, 01762 GSK Investigational Site Berlin, Germany, 10559 GSK Investigational Site Berlin, Germany, 10787 GSK Investigational Site Berlin, Germany, 12051 GSK Investigational Site Hamburg, Germany, 20249 Spain GSK Investigational Site Centelles, Spain GSK Investigational Site La Coruña, Spain, 15006 GSK Investigational Site Madrid, Spain, 28046 GSK Investigational Site Petrer/Alicante, Spain GSK Investigational Site Santiago de Compostela, Spain, 15706 Sweden GSK Investigational Site Göteborg, Sweden, SE-412 55 GSK Investigational Site Göteborg, Sweden, SE-416 85 GSK Investigational Site Helsingborg, Sweden, SE-252 78 GSK Investigational Site Höllviken, Sweden, SE-236 51 GSK Investigational Site Stocholm, Sweden, SE-17176 GSK Investigational Site Upplands Väsby, Sweden, SE-194 89 Less <<
NCT00261586 Analgesics Phase 4 Completed - -
NCT01071317 - Completed - -
NCT00442208 Healthy Phase 1 Completed - United States, North Carolina ... More >> Pozen Inc. Chapel Hill, North Carolina, United States, 27517 Less <<
NCT00913627 Pain Phase 2 Completed - United States, Utah ... More >> Jean Brown Research Center Salt Lake City, Utah, United States, 84124 Less <<
NCT02108548 Pharmacokinetics of ASP7657 ... More >> Pharmacodynamics of ASP7657 Healthy Subjects Less << Phase 1 Terminated(Gastrointestinal sa... More >>fety findings) Less << - United Kingdom ... More >> Parexel Early Phase Clinical Unit Harrow, Middlesex, United Kingdom, HA1 3UJ Less <<
NCT01343303 Osteoarthritis, Knee Phase 1 Completed - South Africa ... More >> George, South Africa Less <<
NCT01442428 Immune Reconstitution Inflamma... More >>tory Syndrome Immune Reconstitution Syndrome Tuberculosis HIV-infection/Aids Less << Phase 2 Phase 3 Withdrawn(2011 Thailand floodi... More >>ng led to loss of GMP pharmacy, project delays, and further regulatory challenges.) Less << June 2016 Thailand ... More >> Ramathibodi Hospital Bangkok, Thailand Chiang Mai University Chiang Mai, Thailand Bamrasnaradura Infectious Diseases Institute Nonthaburi, Thailand Less <<
NCT00913627 - Completed - -
NCT03351439 Hip Pain Chronic Not Applicable Recruiting December 31, 2018 Canada, Ontario ... More >> Fowler Kennedy Sport Medicine Clinic Recruiting London, Ontario, Canada, N6A 3K7 Contact: Ryan M Degen, MD    519-661-2171    ryan.degen@lhsc.on.ca    Contact: Stacey Wanlin       swanlin@uwo.ca    Principal Investigator: Ryan M Degen, MD          Principal Investigator: Kevin Willits, MD Less <<
NCT00674856 Renal Failure Phase 1 Completed - United States, Florida ... More >> Orlando, Florida, United States United States, Minnesota Minneapolis, Minnesota, United States St. Paul, Minnesota, United States Less <<
NCT02307305 Neuropathic Pain Phase 2 Unknown December 2016 Korea, Republic of ... More >> Department of Orthopaedic Surgery, Hanyang University, College of Medicine Recruiting Seoul, Korea, Republic of, 133-792 Contact: Jinkyu Lee    +82-10-9582-7004    gaia-silver@hanmail.net Less <<
NCT00826462 Tennis Elbow ... More >>Epicondylitis, Lateral Humeral Less << Phase 4 Completed - Norway ... More >> Grålum legesenter Sarpsborg, Norway, 1712 Less <<
NCT01417130 - Unknown August 2012 United States, Arizona ... More >> Banner Sun Health Research Institute Sun City, Arizona, United States, 85351 United States, Florida The Roskamp Institute Sarasota, Florida, United States, 34243 United States, Maryland The Johns Hopkins University Baltimore, Maryland, United States, 21205 United States, Massachusetts Boston University School of Medicine Boston, Massachusetts, United States, 02118 United States, New York Monroe Community Hospital Rochester, New York, United States, 14620 United States, Washington Veterans Affairs Puget Sound Health Care System Seattle, Washington, United States, 98108 Less <<
NCT02268305 Low Back Pain Phase 3 Completed - United States, Nevada ... More >> Mike O'Callaghan Federal Medical Center Nellis Air Force Base, Nevada, United States, 89191 Less <<
NCT01374269 Back Pain Lower Back Phase 4 Completed - Colombia ... More >> Clínica de Las Américas Medellin, Antioquia, Colombia Ips Universitaria Medellin, Antioquia, Colombia Less <<
NCT01112553 - Terminated(Study was closed du... More >>e to low enrollment numbers.) Less << - United States, Massachusetts ... More >> Neuroimaging Center, McLean Hospital Belmont, Massachusetts, United States, 02478 Less <<
NCT01688193 - Completed - Korea, Republic of ... More >> Seoul University Hospital Seoul, Korea, Republic of Less <<
NCT01688934 Osteoarthritis, Knee ... More >> Pain Less << Phase 2 Completed - United States, Arizona ... More >> Genova Clinical Research, Inc. Tucson, Arizona, United States, 85704 United States, Florida Orthopedic Research Institute Boynton Beach, Florida, United States, 33472 Avail Clinical Research, LLC Deland, Florida, United States, 32720 Westside Center for Clinical Research Jacksonville, Florida, United States, 32205 Jacksonville Center for Clinical Research Jacksonville, Florida, United States, 32216 Health Awareness, Inc. Jupiter, Florida, United States, 33458 Compass Research, LLC Orlando, Florida, United States, 32806 Compass Research East, LLC Oviedo, Florida, United States, 32765 United States, Indiana Northwest Indiana Center for Clinical Research Valparaiso, Indiana, United States, 46383 United States, Massachusetts Analgesic Solutions Natick, Massachusetts, United States, 01760 United States, Michigan Great Lakes Research Group, Inc. Bay City, Michigan, United States, 48706 United States, North Carolina PMG Research of Charlotte, LLC. Charlotte, North Carolina, United States, 28209 PMG Research of Raleigh, LLC Raleigh, North Carolina, United States, 27609 Wake Research Associates, LLC Raleigh, North Carolina, United States, 27612 United States, Oklahoma LION Research Norman, Oklahoma, United States, 73069 United States, Pennsylvania Altoona Center for Clinical Research Duncansville, Pennsylvania, United States, 16635 Clinical Research Center of Reading, LLP Wyomissing, Pennsylvania, United States, 19610 United States, Tennessee PMG Research of Bristol Bristol, Tennessee, United States, 37620 Less <<
NCT01154790 Healthy Phase 1 Completed - Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of Less <<
NCT02847702 Osteoarthritis Pain of the Kne... More >>e Less << Phase 2 Terminated(Company decision) - -
NCT02604550 Anterior Cruciate Ligament Rec... More >>onstruction Less << Phase 4 Completed - United States, Georgia ... More >> Emory Healthcare Orthopaedics and Spine Center Atlanta, Georgia, United States, 30329 Less <<
NCT01178203 Pulpitis Pain... More >> Management Less << Phase 1 Phase 2 Completed - -
NCT02604550 - Completed - -
NCT02500641 Gout Phase 4 Completed - Germany ... More >> Dresden, Germany Italy Avezzano, Italy Bologna, Italy Brescia, Italy Chieti, Italy Coppito, Italy Netherlands Reade Amsterdam, Netherlands Poland Gdansk, Poland Grudziadz, Poland Katowice, Poland Krakow, Poland Lodz, Poland Warsaw, Poland Zgierz, Poland Romania Bucharest, Romania Craiova, Romania Timisoara, Romania Serbia Belgrade, Serbia Less <<
NCT00433732 Migraine Headaches Phase 3 Completed - United States, Arkansas ... More >> Little Rock Family Practice Clinic Little Rock, Arkansas, United States, 72205 United States, North Carolina Pozen, Inc. Chapel Hill, North Carolina, United States, 27517 Less <<
NCT00981357 Osteoarthritis, Knee Phase 2 Completed - United States, Florida ... More >> Arthritis & Rheumatic Care Center Miami, Florida, United States, 33143 Miami Research Associates Miami, Florida, United States, 33143 United States, Kansas Vince and Associates Clinical Research Overland Park, Kansas, United States, 66211 Vince and Associates Clinical Research Overland Park, Kansas, United States, 66212 United States, Texas CEDRA Clinical Research, LLC San Antonio, Texas, United States, 78217 Canada, Quebec Diex Research Inc. Sherbrooke, Quebec, Canada, J1H 1Z1 Sweden Centrum for klinisk provning Goteborg, Sweden, 405 30 Less <<
NCT00837044 Migraine Headache ... More >> Cognitive Impairment Less << Not Applicable Unknown September 2009 United States, Vermont ... More >> The Neurological Research center, Inc Recruiting Bennington, Vermont, United States, 05201` Principal Investigator: Keith R Edwards, MD Less <<
NCT00114049 Dental Pain S... More >>urgery, Dental Less << Phase 3 Completed - United States, Texas ... More >> GSK Investigational Site Austin, Texas, United States, 78703 Less <<
NCT02202512 Healthy Phase 1 Completed - Germany ... More >> 1333.43.1 Boehringer Ingelheim Investigational Site Berlin, Germany Less <<
NCT01374269 - Completed - -
NCT00602901 Subacute Low Back Pain ... More >> Chronic Low Back Pain Less << Phase 2 Completed - United States, Iowa ... More >> Palmer Center for Chiropractic Research Davenport, Iowa, United States, 52803 The University of Iowa Iowa City, Iowa, United States, 52242 Less <<
NCT00418782 Osteoarthritis Phase 2 Terminated(Results of interim ... More >>analysis indicate lack of efficacy when compared to placebo.) Less << - -
NCT03028870 Osteo Arthritis Knee Phase 2 Completed - -
NCT02355236 Osteoarthritis Phase 4 Unknown December 2015 Korea, Republic of ... More >> Hallym University Medical Center Not yet recruiting Anyang-si, Korea, Republic of Principal Investigator: Moon-Soo Park, M.D.          Inje University Ilsan Paik Hospital Not yet recruiting Goyang-si, Korea, Republic of Principal Investigator: Jin-Hwan Kim, M.D.          Seoul National University Bundang Hospital Not yet recruiting Seongnam-si, Korea, Republic of Principal Investigator: Ho-Joong Kim, M.D.          Asan Medical Center Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Ho-Seong Lee, M.D.          Ewha Womans University Medical Center Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Sang-Jin Shin, M.D.          Gangnam Severance Hospital Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Woo-Suk Lee, M.D.          Hanyang University Seoul Hospital Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Chang-Nam Kang, M.D.          Seoul National University Hospital Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Sang-Hoon Lee, M.D.          Seoul St. Mary's Hospital Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Young-Hoon Kim, M.D.          Severance Hospital Recruiting Seoul, Korea, Republic of Principal Investigator: Seong-Hwan Moon, M.D. Less <<
NCT03028870 - Completed - -
NCT02665286 Low Back Pain Phase 4 Completed - United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less <<
NCT01207115 Osteoarthritis of the Knee Phase 2 Completed - -
NCT02665286 - Completed - -
NCT00626275 Rheumatoid Arthritis Phase 2 Completed - United States, Connecticut ... More >> New England Research Associates Trumbull, Connecticut, United States, 06611 United States, Florida Covance Clinical Research Unit Inc. Daytona Beach, Florida, United States, 32117 United States, Maryland The Center for Rheumatology and Bone Research Wheaton, Maryland, United States, 20901 United States, Nebraska Heartland Clinical Research, Inc. Omaha, Nebraska, United States, 68134 United States, Nevada Advanced Biomedical Research of America Las Vegas, Nevada, United States, 89123 United States, New York Winthrop University Hospital, Clinical Trials Center Mineola, New York, United States, 11501 United States, Ohio University Hospitals Case Medical Center, Division of Rheumatology, Rheumatology Clinical Research Unit Beachwood, Ohio, United States, 44122 United States, Pennsylvania Altoona Center for Clinical Research Duncansville, Pennsylvania, United States, 16635-8406 Less <<
NCT02986334 Chronic Low Back Pain Phase 4 Unknown September 2018 United States, Illinois ... More >> Northwestern University Feinberg School of Medicine Recruiting Chicago, Illinois, United States, 60611 Contact: Taha B Abdullah, M.S.    312-451-8468    taha.abdullah1@northwestern.edu Less <<
NCT00594854 - Terminated(POZEN agreed with F... More >>DA to stop study due to low and inadequate enrollment) Less << - -
NCT00626275 - Completed - -
NCT02712957 Pain Osteoart... More >>hritis of the Knee Less << Phase 2 Completed - Canada, Quebec ... More >> Diex Recherche Montreal Inc Montreal, Quebec, Canada, H2Y 1S1 Algorithme Pharma Montreal, Quebec, Canada, H3P 3P1 Diex Recherche Sherbrooke Inc Sherbrooke, Quebec, Canada, J1H 1Z1 Less <<
NCT00442221 Migraine Headaches Phase 3 Completed - United States, North Carolina ... More >> POZEN Inc. Chapel Hill, North Carolina, United States, 27517 Headache Wellness Center Greensboro, North Carolina, United States, 27401 Less <<
NCT00676442 Arthritis Phase 1 Completed - United States, Texas ... More >> Austin, Texas, United States Less <<
NCT02646124 Low Back Pain Phase 2 Phase 3 Completed - United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less <<
NCT02646124 - Completed - -
NCT00392080 Osteoarthritis Phase 1 Completed - United States, California ... More >> Pfizer Investigational Site Anaheim, California, United States, 92801 Pfizer Investigational Site San Diego, California, United States, 92103-6204 United States, Florida Pfizer Investigational Site Jupiter, Florida, United States, 33458 Pfizer Investigational Site Ocoee, Florida, United States, 34761 Pfizer Investigational Site South Miami, Florida, United States, 33143 United States, New York Pfizer Investigational Site New York, New York, United States, 10021 United States, North Carolina Pfizer Investigational Site Raleigh, North Carolina, United States, 27607 Pfizer Investigational Site Raleigh, North Carolina, United States, 27612 United States, Texas Pfizer Investigational Site Houston, Texas, United States, 77074 Pfizer Investigational Site Houston, Texas, United States, 77090 United States, Virginia Pfizer Investigational Site Chesapeake, Virginia, United States, 23320 Less <<
NCT00007189 Alzheimer Disease Phase 3 Completed - United States, Arizona ... More >> Sun Health Research Institute Sun City, Arizona, United States, 85351 United States, Florida Roskamp Institute Memory Clinic, 10770 N. 46th Street Tampa, Florida, United States, 33617 United States, Maryland Johns Hopkins University Baltimore, Maryland, United States, 21287 United States, Massachusetts Boston University School of Medicine Boston, Massachusetts, United States, 02118 United States, New York University of Rochester Rochester, New York, United States, 14620 United States, Washington Veterans Affairs Puget Sound Health Care System, University of Washington Seattle, Washington, United States, 98108 Less <<
NCT00945178 Healthy Volunteers Phase 1 Terminated(The study was termi... More >>nated due to results in another study (NCT00878501).) Less << - United Kingdom ... More >> Research Site Harrow, United Kingdom Less <<
NCT00594854 Gastric Ulcer Phase 3 Terminated(POZEN agreed with F... More >>DA to stop study due to low and inadequate enrollment) Less << - United States, North Carolina ... More >> POZEN Chapel Hill, North Carolina, United States, 27517 Less <<
NCT03570554 Osteoarthritis, Knee Phase 2 Recruiting March 24, 2019 United States, Arizona ... More >> Radiant Research, Inc. Recruiting Chandler, Arizona, United States, 85224 United States, Florida Radiant Research, Inc. Recruiting Pinellas Park, Florida, United States, 33781 United States, Illinois Radiant Research, Inc. Recruiting Chicago, Illinois, United States, 60602 United States, Ohio Radiant Research, Inc. Recruiting Cincinnati, Ohio, United States, 45236 United States, Texas Radiant Research, Inc. Recruiting San Antonio, Texas, United States, 78229 Less <<
NCT02484170 Neuralgia, Postherpetic Phase 1 Phase 2 Completed - Canada, British Columbia ... More >> Dr. Helene Bertrand Inc. North Vancouver, British Columbia, Canada, V7M 2K2 Less <<
NCT00819585 Gout Phase 2 Completed - -
NCT00034853 Arthritis, Juvenile Rheumatoid Phase 3 Completed - -
NCT02116790 Acute Pain Phase 2 Withdrawn January 2015 -
NCT03084536 Breast Cancer ... More >> Breast Cancer Female Cancer of Breast Less << Phase 2 Recruiting June 30, 2020 United States, Missouri ... More >> Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Ryan C Guffey, M.D.    314-286-2883    rguffey@wustl.edu    Principal Investigator: Ryan C Guffey, M.D.          Sub-Investigator: Mitchell E Fingerman, M.D.          Sub-Investigator: Erin Gibbons, M.D.          Sub-Investigator: Susan Ironstone, M.D.          Sub-Investigator: Arbi Ben Abdallah          Sub-Investigator: Rebecca L Aft, M.D.          Sub-Investigator: Amy E Cyr, M.D.          Sub-Investigator: Julie A Margenthaler, M.D.          Sub-Investigator: Simon Haroutounian, Ph.D., MSC          Sub-Investigator: Michael S Avidan, MBBCH Less <<
NCT00819585 - Completed - -
NCT03651804 Vertebral Compression Fracture... More >> Facet Joint Pain Less << Phase 4 Recruiting October 1, 2019 United States, California ... More >> UC Davis Medical Center Recruiting Davis, California, United States, 95817 Contact: Jaimish Gwalani, MD    510-386-7942    jgwalani@ucdavis.edu    Contact: Christopher Migdal, BS    4156728991    cwmigdal@ucdavis.edu Less <<
NCT01760954 - Completed - -
NCT01760954 Endometriosis Phase 3 Completed - -
NCT04145518 Dysmenorrhea (Disorder)|Dysmen... More >>orrhea Primary|Dysmenorrhea Secondary|Endometrial Diseases|Leiomyoma|Fibroid Uterus Less << PHASE4 RECRUITING 2024-09-01 NorthShore University HealthSy... More >>stem, Evanston, Illinois, 60201, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.96mL

0.79mL

0.40mL

19.82mL

3.96mL

1.98mL

39.64mL

7.93mL

3.96mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

References

 

Historical Records

Categories