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Chemical Structure| 839713-36-9 Chemical Structure| 839713-36-9

Structure of Nelotanserin
CAS No.: 839713-36-9

Chemical Structure| 839713-36-9

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Nelotanserin is a potent selective 5-HT2A inverse agonist, showing low nanomolar potency on the 5-HT2A receptor with at least 30- and 5000-fold selectivity compared with 5-HT2C and 5-HT2B receptors.

Synonyms: APD125

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Product Details of Nelotanserin

CAS No. :839713-36-9
Formula : C18H15BrF2N4O2
M.W : 437.24
SMILES Code : O=C(NC1=CC=C(F)C=C1F)NC2=CC=C(OC)C(C3=C(Br)C=NN3C)=C2
Synonyms :
APD125
MDL No. :MFCD16619341
InChI Key :COSPVUFTLGQDQL-UHFFFAOYSA-N
Pubchem ID :11683556

Safety of Nelotanserin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Nelotanserin

GPCR

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00452179 Insomnia PHASE2 COMPLETED 2025-06-07 San Diego, California, 92121, ... More >>United States Less <<
NCT02871427 Lewy Body Dementia|Dementia Wi... More >>th Lewy Bodies|Parkinson's Disease Dementia|Visual Hallucinations|REM Sleep Behavior Disorder Less << PHASE2 TERMINATED 2019-01-17 US120, Birmingham, Alabama, 35... More >>294, United States|US143, Little Rock, Arkansas, 77205, United States|US114, Boca Raton, Florida, 33486, United States|US180, Maitland, Florida, 32751, United States|US154, Ocala, Florida, 34471, United States|US113, Orlando, Florida, 32806, United States|US152, Ormond Beach, Florida, 32174, United States|US107, Indianapolis, Indiana, 46202, United States|US132, Lenexa, Kansas, 66214, United States|US103, Rochester, Minnesota, 55905, United States|US129, Lincoln, Nebraska, 68526, United States|US101, Chapel Hill, North Carolina, 27514, United States|US147, Fargo, North Dakota, 58103, United States|US111, Cincinnati, Ohio, 45229, United States|US104, Cleveland, Ohio, 44195, United States|US105, Columbus, Ohio, 43210, United States|US173, Lincoln, Rhode Island, 02865, United States|US128, Memphis, Tennessee, 38163, United States|US131, San Antonio, Texas, 78229, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.29mL

0.46mL

0.23mL

11.44mL

2.29mL

1.14mL

22.87mL

4.57mL

2.29mL

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