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Chemical Structure| 2380230-73-7 Chemical Structure| 2380230-73-7

Structure of NF-56-EJ40
CAS No.: 2380230-73-7

Chemical Structure| 2380230-73-7

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NF-56-EJ40 is a high-affinity and highly selective antagonist of human SUCNR1 (GPR91) (IC50 of 25 nM).

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Product Details of NF-56-EJ40

CAS No. :2380230-73-7
Formula : C27H29N3O3
M.W : 443.54
SMILES Code : CN1CCN(CC2=CC=C(C3=CC(C(NC4=CC=CC=C4CC(O)=O)=O)=CC=C3)C=C2)CC1
MDL No. :MFCD32263439
InChI Key :UTWXDNZWMQAUKL-UHFFFAOYSA-N
Pubchem ID :138811017

Safety of NF-56-EJ40

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of NF-56-EJ40

GPCR

Isoform Comparison

Biological Activity

Description
NF-56-EJ40 is a potent and highly selective antagonist of human SUCNR1 (GPR91), demonstrating high affinity with an IC50 value of 25 nM and a Ki of 33 nM. It exhibits minimal activity against rat SUCNR1. Notably, NF-56-EJ40 possesses significant affinity for humanized rat SUCNR1, with a Ki of 17.4 nM[1].

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22.55mL

4.51mL

2.25mL

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