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Chemical Structure| 1912422-56-0 Chemical Structure| 1912422-56-0

Structure of NFATc1-IN-1
CAS No.: 1912422-56-0

Chemical Structure| 1912422-56-0

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NFATc1-IN-1 is a potent inhibitor of RANKL-induced osteoclast formation with an IC50 of 1.57 μM. It exhibits anti-osteoclast activity by reducing NFATc1 nuclear translocation, making it suitable for research on osteoclastic diseases.

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Product Details of NFATc1-IN-1

CAS No. :1912422-56-0
Formula : C13H8F2INO2
M.W : 375.10
SMILES Code : O=C(NC1=CC=C(I)C=C1F)C2=CC(F)=CC=C2O

Safety of NFATc1-IN-1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P264-P270-P301+P312-P330-P501

Isoform Comparison

Biological Activity

Description
NFATc1-IN-1 is a potent inhibitor of RANKL-induced osteoclast formation, demonstrating an IC50 of 1.57 μM. It exhibits anti-osteoclastogenic effects by reducing RANKL-induced NFATc1 nuclear translocation and is suitable for research into osteoclastic diseases[1].

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Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.67mL

0.53mL

0.27mL

13.33mL

2.67mL

1.33mL

26.66mL

5.33mL

2.67mL

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