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Chemical Structure| 6506-37-2 Chemical Structure| 6506-37-2

Structure of Nimorazole
CAS No.: 6506-37-2

Chemical Structure| 6506-37-2

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Nimorazole is a nitroimidazole anti-infective.

Synonyms: K-1900; Acterol; NSC 107524

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Product Details of Nimorazole

CAS No. :6506-37-2
Formula : C9H14N4O3
M.W : 226.23
SMILES Code : O=[N+](C1=CN=CN1CCN2CCOCC2)[O-]
Synonyms :
K-1900; Acterol; NSC 107524
MDL No. :MFCD00866796
InChI Key :MDJFHRLTPRPZLY-UHFFFAOYSA-N
Pubchem ID :23009

Safety of Nimorazole

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H319-H372-H410
Precautionary Statements:P501-P273-P260-P270-P264-P280-P391-P314-P337+P313-P305+P351+P338-P301+P312+P330
Class:9
UN#:3077
Packing Group:

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02976051 Locally Advanced Head and Neck... More >> Cancer Radiotherapy Less << Phase 2 Recruiting December 2021 Denmark ... More >> Department of Experimental Clinical Oncology, Aarhus University Hospital Recruiting Aarhus, Denmark, 8000 C Contact: Jens Overgaard, Prof., MD    +45 7846 2629    jens@oncology.au.dk    Contact: Mette Saxø, MD    +89492619    mette.saksoe@oncology.au.dk Less <<
NCT01733823 HNSCC,Larynx, Pharynx and Oral... More >> Cavity Less << Phase 1 Phase 2 Completed - Denmark ... More >> Aarhus Aarhus, Aarhus C, Denmark, 8000 Odense Odense, Odense C, Denmark, 5000 Aalborg Aalborg, Denmark, 9100 Herlev Herlev, Denmark, 2730 Less <<
NCT01880359 Locally Advanced Head and Neck... More >> HPV Negative Squamous Cell Cancers Less << Phase 3 Active, not recruiting December 2020 Australia ... More >> Royal Brisbane And Women's Hospital Brisbane, Australia, QLD 4029 Princess Alexandra Hospital - University Of Queensland Brisbane, Australia, QLD 4102 Royal North Shore Hospital St Leonards, Australia, NSW 2065 Belgium Hopitaux Universitaires Bordet-Erasme - Institut Jules Bordet Brussels, Belgium, 1000 Cliniques Universitaires Saint-Luc Brussels, Belgium, 1200 U.Z. Leuven - Campus Gasthuisberg Leuven, Belgium, 3000 France Centre Georges-Francois-Leclerc Dijon, France, 21079 CHU de Tours - Hopital Bretonneau Tours, France, 37044 Institut Gustave Roussy Villejuif, France, 94805 Germany Charite - Universitaetsmedizin Berlin - Campus Virchow-Klinikum Berlin, Germany Ludwig-Maximilians-Universitaet Muenchen - Klinikum der Universitaet Muenchen - Campus Grosshadern Muenchen, Germany, 81377 Netherlands Vrije Universiteit Medisch Centrum Amsterdam, Netherlands, 7007MB Radboud University Medical Center Nijmegen Nijmegen, Netherlands, 6500 H Poland Medical University Of Gdansk Gdansk, Poland, 80 211 The Great Poland Cancer Centre Poznan, Poland Maria Sklodowska-Curie Memorial Cancer Centre Warsaw, Poland Lower Silesian Oncology Centre Wrocław, Poland Switzerland Hôpitaux universitaires de Genève - HUG - site de Cluse-Roseraie Geneva, Switzerland, 1211 UniversitaetsSpital Zurich Zurich, Switzerland, 8091 Less <<
NCT02661152 Head and Neck Squamous Cell Ca... More >>rcinoma|Radiotherapy|Hypoxic Modification|Hypoxia|Gene Profile, Gene Signature Less << PHASE3 UNKNOWN 2025-12-23 Department of Experimental Cli... More >>nical Oncology, Aarhus University Hospital, Aarhus, 8000 C, Denmark Less <<
NCT01950689 Head and Neck Squamous Cell Ca... More >>rcinoma Less << Phase 3 Recruiting June 2021 United Kingdom ... More >> Cheltenham General Hospital Recruiting Cheltenham, Gloucestershire, United Kingdom, GL53 7AN Principal Investigator: Warren Grant          Clatterbridge Centre for Oncology Recruiting Bebington, Merseyside, United Kingdom, CH63 4JY Principal Investigator: David Husband          St James' Hospital Recruiting Leeds, West Yorkshire, United Kingdom, LS9 7TF Principal Investigator: Mehmet Sen          Belfast City Hospital Recruiting Belfast, United Kingdom, BT9 7AB Contact: Fiona McCloskey          Queen Elizabeth Hospital Suspended Birmingham, United Kingdom, B15 2TH Bradford Teaching Hospitals NHS Foundation Trust Recruiting Bradford, United Kingdom, BD9 6RJ Principal Investigator: Michael Ho          Bristol Haematology and Oncology centre Recruiting Bristol, United Kingdom, BS2 8ED Principal Investigator: Hoda Booz          Addenbrookes Hospital Recruiting Cambridge, United Kingdom, CB2 0QQ Principal Investigator: Gill Barnett          Velindre Cancer Centre Recruiting Cardiff, United Kingdom, CF14 2TL Principal Investigator: Mererid Evans          University Hospitals Coventry and Warwickshire Recruiting Coventry, United Kingdom, CV2 2DX Principal Investigator: Andrew Chan          The Beatson West of Scotland Cancer Centre Recruiting Glasgow, United Kingdom, G12 0YN Principal Investigator: Stefano Schipani          The Royal Surrey County Hospital Recruiting Guildford, United Kingdom, GU2 7XX Principal Investigator: Katie Wood          Leicester Royal Infirmary Recruiting Leicester, United Kingdom, LE1 5WW Principal Investigator: Thiagarajan Sridhar          University College London Hospital Recruiting London, United Kingdom, NW1 2PG Principal Investigator: Ruheena Mendes          The Royal Marsden Recruiting London, United Kingdom, SW3 6JJ Principal Investigator: Chris Nutting          The Christie NHS Foundation Trust Recruiting Manchester, United Kingdom, M20 4BX Principal Investigator: Nick Slevin          The James Cook University Hospital Suspended Middlesborough, United Kingdom, TS4 3BW Mount Vernon Recruiting Middlesex, United Kingdom, HA6 2RN Principal Investigator: Catherine Lemon          Freeman Hospital Withdrawn Newcastle, United Kingdom, NE7 7DN Nottingham University Hospitals Recruiting Nottingham, United Kingdom, NG5 1PB Principal Investigator: Judith Christian          Weston Park Hospital Recruiting Sheffield, United Kingdom, S10 2SJ Principal Investigator: Bernadette Foran          Singleton Hospital Recruiting Swansea, United Kingdom, SA2 8QA Principal Investigator: Russell Banner          York Hospital Recruiting York, United Kingdom, Y031 8HE Principal Investigator: Robin Prestwich Less <<
NCT01507467 Head and Neck Carcinoma Phase 3 Terminated(Insufficient recrui... More >>tment) Less << - Egypt ... More >> Radiation Oncology Department, National Cancer Institute Cairo, Egypt Estonia Radiation Oncology Center Tallin, Estonia, 13419 Pakistan Nuclear Medicine, Oncology & Radiotherapy Institute, Radiation Oncology Department G-8/3 Islamabad, Pakistan Karachi Institute of Radiotherapy and Nuclear Medicine Karachi, Pakistan Institute of Radiotherapy and Nuclear Medicine (IRNUM) Hospital Peshawar Peshawar, Pakistan Slovenia Institute of Oncology Department of Radiation Oncology Ljubljana, Slovenia Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.42mL

0.88mL

0.44mL

22.10mL

4.42mL

2.21mL

44.20mL

8.84mL

4.42mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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