Structure of Nimorazole
CAS No.: 6506-37-2
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Nimorazole is a nitroimidazole anti-infective.
Synonyms: K-1900; Acterol; NSC 107524
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Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
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CAS No. : | 6506-37-2 |
Formula : | C9H14N4O3 |
M.W : | 226.23 |
SMILES Code : | O=[N+](C1=CN=CN1CCN2CCOCC2)[O-] |
Synonyms : |
K-1900; Acterol; NSC 107524
|
MDL No. : | MFCD00866796 |
InChI Key : | MDJFHRLTPRPZLY-UHFFFAOYSA-N |
Pubchem ID : | 23009 |
GHS Pictogram: |
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Signal Word: | Danger |
Hazard Statements: | H302-H319-H372-H410 |
Precautionary Statements: | P501-P273-P260-P270-P264-P280-P391-P314-P337+P313-P305+P351+P338-P301+P312+P330 |
Class: | 9 |
UN#: | 3077 |
Packing Group: | Ⅲ |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT02976051 | Locally Advanced Head and Neck... More >> Cancer Radiotherapy Less << | Phase 2 | Recruiting | December 2021 | Denmark ... More >> Department of Experimental Clinical Oncology, Aarhus University Hospital Recruiting Aarhus, Denmark, 8000 C Contact: Jens Overgaard, Prof., MD +45 7846 2629 jens@oncology.au.dk Contact: Mette Saxø, MD +89492619 mette.saksoe@oncology.au.dk Less << |
NCT01733823 | HNSCC,Larynx, Pharynx and Oral... More >> Cavity Less << | Phase 1 Phase 2 | Completed | - | Denmark ... More >> Aarhus Aarhus, Aarhus C, Denmark, 8000 Odense Odense, Odense C, Denmark, 5000 Aalborg Aalborg, Denmark, 9100 Herlev Herlev, Denmark, 2730 Less << |
NCT01880359 | Locally Advanced Head and Neck... More >> HPV Negative Squamous Cell Cancers Less << | Phase 3 | Active, not recruiting | December 2020 | Australia ... More >> Royal Brisbane And Women's Hospital Brisbane, Australia, QLD 4029 Princess Alexandra Hospital - University Of Queensland Brisbane, Australia, QLD 4102 Royal North Shore Hospital St Leonards, Australia, NSW 2065 Belgium Hopitaux Universitaires Bordet-Erasme - Institut Jules Bordet Brussels, Belgium, 1000 Cliniques Universitaires Saint-Luc Brussels, Belgium, 1200 U.Z. Leuven - Campus Gasthuisberg Leuven, Belgium, 3000 France Centre Georges-Francois-Leclerc Dijon, France, 21079 CHU de Tours - Hopital Bretonneau Tours, France, 37044 Institut Gustave Roussy Villejuif, France, 94805 Germany Charite - Universitaetsmedizin Berlin - Campus Virchow-Klinikum Berlin, Germany Ludwig-Maximilians-Universitaet Muenchen - Klinikum der Universitaet Muenchen - Campus Grosshadern Muenchen, Germany, 81377 Netherlands Vrije Universiteit Medisch Centrum Amsterdam, Netherlands, 7007MB Radboud University Medical Center Nijmegen Nijmegen, Netherlands, 6500 H Poland Medical University Of Gdansk Gdansk, Poland, 80 211 The Great Poland Cancer Centre Poznan, Poland Maria Sklodowska-Curie Memorial Cancer Centre Warsaw, Poland Lower Silesian Oncology Centre Wrocław, Poland Switzerland Hôpitaux universitaires de Genève - HUG - site de Cluse-Roseraie Geneva, Switzerland, 1211 UniversitaetsSpital Zurich Zurich, Switzerland, 8091 Less << |
NCT02661152 | Head and Neck Squamous Cell Ca... More >>rcinoma|Radiotherapy|Hypoxic Modification|Hypoxia|Gene Profile, Gene Signature Less << | PHASE3 | UNKNOWN | 2025-12-23 | Department of Experimental Cli... More >>nical Oncology, Aarhus University Hospital, Aarhus, 8000 C, Denmark Less << |
NCT01950689 | Head and Neck Squamous Cell Ca... More >>rcinoma Less << | Phase 3 | Recruiting | June 2021 | United Kingdom ... More >> Cheltenham General Hospital Recruiting Cheltenham, Gloucestershire, United Kingdom, GL53 7AN Principal Investigator: Warren Grant Clatterbridge Centre for Oncology Recruiting Bebington, Merseyside, United Kingdom, CH63 4JY Principal Investigator: David Husband St James' Hospital Recruiting Leeds, West Yorkshire, United Kingdom, LS9 7TF Principal Investigator: Mehmet Sen Belfast City Hospital Recruiting Belfast, United Kingdom, BT9 7AB Contact: Fiona McCloskey Queen Elizabeth Hospital Suspended Birmingham, United Kingdom, B15 2TH Bradford Teaching Hospitals NHS Foundation Trust Recruiting Bradford, United Kingdom, BD9 6RJ Principal Investigator: Michael Ho Bristol Haematology and Oncology centre Recruiting Bristol, United Kingdom, BS2 8ED Principal Investigator: Hoda Booz Addenbrookes Hospital Recruiting Cambridge, United Kingdom, CB2 0QQ Principal Investigator: Gill Barnett Velindre Cancer Centre Recruiting Cardiff, United Kingdom, CF14 2TL Principal Investigator: Mererid Evans University Hospitals Coventry and Warwickshire Recruiting Coventry, United Kingdom, CV2 2DX Principal Investigator: Andrew Chan The Beatson West of Scotland Cancer Centre Recruiting Glasgow, United Kingdom, G12 0YN Principal Investigator: Stefano Schipani The Royal Surrey County Hospital Recruiting Guildford, United Kingdom, GU2 7XX Principal Investigator: Katie Wood Leicester Royal Infirmary Recruiting Leicester, United Kingdom, LE1 5WW Principal Investigator: Thiagarajan Sridhar University College London Hospital Recruiting London, United Kingdom, NW1 2PG Principal Investigator: Ruheena Mendes The Royal Marsden Recruiting London, United Kingdom, SW3 6JJ Principal Investigator: Chris Nutting The Christie NHS Foundation Trust Recruiting Manchester, United Kingdom, M20 4BX Principal Investigator: Nick Slevin The James Cook University Hospital Suspended Middlesborough, United Kingdom, TS4 3BW Mount Vernon Recruiting Middlesex, United Kingdom, HA6 2RN Principal Investigator: Catherine Lemon Freeman Hospital Withdrawn Newcastle, United Kingdom, NE7 7DN Nottingham University Hospitals Recruiting Nottingham, United Kingdom, NG5 1PB Principal Investigator: Judith Christian Weston Park Hospital Recruiting Sheffield, United Kingdom, S10 2SJ Principal Investigator: Bernadette Foran Singleton Hospital Recruiting Swansea, United Kingdom, SA2 8QA Principal Investigator: Russell Banner York Hospital Recruiting York, United Kingdom, Y031 8HE Principal Investigator: Robin Prestwich Less << |
NCT01507467 | Head and Neck Carcinoma | Phase 3 | Terminated(Insufficient recrui... More >>tment) Less << | - | Egypt ... More >> Radiation Oncology Department, National Cancer Institute Cairo, Egypt Estonia Radiation Oncology Center Tallin, Estonia, 13419 Pakistan Nuclear Medicine, Oncology & Radiotherapy Institute, Radiation Oncology Department G-8/3 Islamabad, Pakistan Karachi Institute of Radiotherapy and Nuclear Medicine Karachi, Pakistan Institute of Radiotherapy and Nuclear Medicine (IRNUM) Hospital Peshawar Peshawar, Pakistan Slovenia Institute of Oncology Department of Radiation Oncology Ljubljana, Slovenia Less << |
Tags: Nimorazole | K-1900 | Antiparasitic | Anti-Infection | 6506-37-2
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
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