Home Cart Sign in  
Chemical Structure| 6300-44-3 Chemical Structure| 6300-44-3

Structure of NSC45586 sodium
CAS No.: 6300-44-3

Chemical Structure| 6300-44-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

NSC45586 Sodium is a PHLPP inhibitor that targets the phosphatase domain of PHLPP to activate the AKT pathway.

Synonyms: NSC45586

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of NSC45586 sodium

CAS No. :6300-44-3
Formula : C20H17N6NaO3
M.W : 412.38
SMILES Code : O=C([O-])C1=CC(/N=N/C2=CC=C(/N=N/C3=CC(C)=C(N)C=C3N)C=C2)=CC=C1O.[Na+]
Synonyms :
NSC45586
MDL No. :MFCD33029321

Safety of NSC45586 sodium

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of NSC45586 sodium

PI3K-AKT

Isoform Comparison

Biological Activity

Description
As a PHLPP phosphatase inhibitor, NSC45586 sodium acts on the pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP), specifically targeting the PP2C domain within PHLPP1 and PHLPP2, thereby inducing AKT activation in neuronal cells[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.42mL

0.48mL

0.24mL

12.12mL

2.42mL

1.21mL

24.25mL

4.85mL

2.42mL

References

 

Historical Records

Categories