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Chemical Structure| 2272917-13-0 Chemical Structure| 2272917-13-0

Structure of NT-0796
CAS No.: 2272917-13-0

Chemical Structure| 2272917-13-0

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NT-0796 is a selective NLRP3 inflammasome inhibitor that penetrates the central nervous system, with an IC50 of 0.32 nM in PBMCs. NT-0796 converts to the active substance NDT-197959 in vivo, applicable for research on neuroinflammatory diseases, particularly in the treatment of central nervous system disorders.

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Product Details of NT-0796

CAS No. :2272917-13-0
Formula : C23H27N3O4
M.W : 409.48
SMILES Code : O=C(OC(C)C)[C@H](OC(NC1=C2CCCC2=CC3=C1CCC3)=O)CC4=NC=CC=N4
MDL No. :N/A

Safety of NT-0796

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT06129409 Cardiovascular Diseases PHASE1 COMPLETED 2024-04-15 Investigative Site, Miami, Flo... More >>rida, 33147, United States|Investigative Site, Austin, Texas, 78744, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.44mL

0.49mL

0.24mL

12.21mL

2.44mL

1.22mL

24.42mL

4.88mL

2.44mL

 

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