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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 3689-50-7 Chemical Structure| 3689-50-7

Structure of Oxomemazine
CAS No.: 3689-50-7

Chemical Structure| 3689-50-7

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Oxomemazine is a phenothiazine-based histamine H1 receptor antagonist with notable anticholinergic activity and selective antagonism at muscarinic M1 receptors, showing a 20-fold difference in affinity at high (histamine H1-receptor = 84 nM, M1 receptor) and low (histamine H1-receptor = 1.65 μM, M2 receptor) affinity sites. It can be used as an antihistamine and anticholinergic agent for cough-related studies.

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Product Details of Oxomemazine

CAS No. :3689-50-7
Formula : C18H22N2O2S
M.W : 330.44
SMILES Code : CC(CN(C)C)CN1C2=C(C=CC=C2)S(C3=CC=CC=C13)(=O)=O
MDL No. :MFCD00868197
InChI Key :QTQPVLDZQVPLGV-UHFFFAOYSA-N
Pubchem ID :19396

Safety of Oxomemazine

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H330
Precautionary Statements:P260-P280-P284-P310
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Oxomemazine

GPCR

Isoform Comparison

Biological Activity

Description
Oxomemazine, a phenothiazine-based histamine H1-receptor antagonist, exhibits significant antimuscarinic effects. It acts as a selective antagonist for the muscarinic M1 receptor, demonstrating approximately a 20-fold difference in affinity between high (Ki = 84 nM, M1 receptor) and low (Ki = 1.65 μM, M2 receptor) affinity sites[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.03mL

0.61mL

0.30mL

15.13mL

3.03mL

1.51mL

30.26mL

6.05mL

3.03mL

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