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Mouse FcRL1 +SDS-PAGE.jpg Mouse FcRL1 +SDS-PAGE.jpg Greater than 95% as determined by reducing SDS-PAGE.

Greater than 95% as determined by reducing SDS-PAGE.

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Recombinant Mouse FcRL1 (C-6His, HEK293) is a mouse-derived Fc receptor-like protein 1, expressed in HEK293 human cells and tagged with a C-terminal 6×His tag. This protein is a type I single-pass transmembrane protein, predominantly expressed at various stages of B cell differentiation. Its extracellular region contains two immunoglobulin-like domains and may function as a co-receptor involved in B cell activation and differentiation, rather than serving as an Ig receptor.

Synonyms: Recombinant Mouse FcRL1 (C-6His, HEK293); Fc receptor-like protein 1; FcR-like protein 1

4.5 *For Research Use Only !

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Product Details of Mouse FcRL1 (C-6His, HEK293)

M.W : 22.5 KDa
SMILES Code : NONE
Synonyms :
Recombinant Mouse FcRL1 (C-6His, HEK293); Fc receptor-like protein 1; FcR-like protein 1

Safety of Mouse FcRL1 (C-6His, HEK293)

Isoform Comparison

Biological Activity

Description
Mouse Fc receptor-like protein 1 (FCRL1) is a single-pass type I membrane protein. It is expressed in B-cells at the various stages of differentiation. Mouse FCRL1 consists of a 203 amino acid (aa) extracellular domain (ECD) with two Ig‑like domains, a 21 aa transmembrane segment, and a 103 aa cytoplasmic domain with two immunotyrosine activation motifs (ITAMs). FCRL1 is likely not a receptor for immunoglobulin. It may function as an activating coreceptor in B-cells and B-cells differentiation.
Protein Species Mouse
Expression System Human Cells
Tag C-6His
Protein Expression Interval Ala17-Ser219
Protein ID BAC30017.1
Endotoxin < 1 EU/µg as determined by LAL test.
Characteristics Lyophilized powder
Formulation Description Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Method Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
For long-term storage, it is recommended to further dilute the product with a solution containing carrier proteins (e.g., 0.1% BSA, 10% FBS, or 5% HSA). For serum-free cultures or in vivo animal experiments where BSA, FBS, or HSA cannot be present in the cytokine preparation, trehalose may be used as an alternative carrier. Aliquots should be stored frozen at -20°C to -80°C.
Note: Low-adsorption tubes are recommended for aliquot storage, and repeated freeze-thaw cycles should be avoided. The dilution concentration for aliquoting should not be lower than 10 μg/mL, and the aliquot volume should be no less than 10 μL.
Aliquoted protein remains stable for up to 3 months when stored at ≤ -20°C.
 

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