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Chemical Structure| 269718-83-4 Chemical Structure| 269718-83-4

Structure of Pardoprunox HCl
CAS No.: 269718-83-4

Chemical Structure| 269718-83-4

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Pardoprunox HCl is a partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.

Synonyms: DU-126891 hydrochloride; SLV-308 hydrochloride; SLV 308

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Product Details of Pardoprunox HCl

CAS No. :269718-83-4
Formula : C12H16ClN3O2
M.W : 269.73
SMILES Code : O=C1OC2=C(N3CCN(C)CC3)C=CC=C2N1.[H]Cl
Synonyms :
DU-126891 hydrochloride; SLV-308 hydrochloride; SLV 308
MDL No. :MFCD09833663
InChI Key :NQRIKTDKFHAOKC-UHFFFAOYSA-N
Pubchem ID :6918524

Safety of Pardoprunox HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Pardoprunox HCl

GPCR

Isoform Comparison

Biological Activity

Description
Pardoprunox (SLV-308) hydrochloride is a partial agonist at dopamine D2 and D3 receptors, with pEC50s of 8 and 9.2, respectively, and acts as a serotonin 5-HT1A receptor agonist with a pEC50 of 6.3[1].

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1 mM

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10 mM

3.71mL

0.74mL

0.37mL

18.54mL

3.71mL

1.85mL

37.07mL

7.41mL

3.71mL

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