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Structure of Paricalcitol
CAS No.: 131918-61-1
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Paricalcitol, a vitamin D analogue, acts as a vitamin D receptor agonist and is used to prevent and treat secondary hyperparathyroidism associated with chronic renal failure.
Synonyms: 1α,25-Dihydroxy-19-nor-vitamin D2; Zemplar; paricalcitol-d6
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CAS No. : | 131918-61-1 |
Formula : | C27H44O3 |
M.W : | 416.64 |
SMILES Code : | C[C@]([C@]([C@H](C)/C=C/[C@H](C)C(C)(C)O)([H])CC1)(CCC/2)[C@]1([H])C2=C\C=C3C[C@@H](O)C[C@H](O)C/3 |
Synonyms : |
1α,25-Dihydroxy-19-nor-vitamin D2; Zemplar; paricalcitol-d6
|
MDL No. : | MFCD08067734 |
GHS Pictogram: |
![]() ![]() |
Signal Word: | Danger |
Hazard Statements: | H301+H311-H330-H372 |
Precautionary Statements: | P260-P280-P302+P352+P312-P304+P340+P310-P403+P233 |
Class: | 6.1 |
UN#: | 2811 |
Packing Group: | Ⅰ |
In Vitro:
Concentration | Treated Time | Description | References |
N2a cells | 15 nM | 24 hours | To evaluate the effect of Paricalcitol on Aβ42 oligomer-induced cell death. Results showed that Paricalcitol significantly reduced Aβ42 oligomer-induced mitochondrial 8-OHdG generation and increased cell viability. | PMC6642335 |
N2a-sw cells | 0-30 nM | 24 hours | To evaluate the effect of Paricalcitol on BACE1 expression in N2a-sw cells. Results showed that Paricalcitol dramatically downregulated BACE1 expression in a dose-dependent manner without altering the expression of APP, ADAM10, or PS1. | PMC6642335 |
HK-2 cells | 400 nM | 24 hours | To investigate the protective effect of Paricalcitol on Erastin-induced cell death, results showed that Paricalcitol pretreatment significantly alleviated Erastin-induced cell death | PMC6989512 |
HK-2 cells | 400 nM | 24 hours | To investigate the protective effect of Paricalcitol on cisplatin-induced tubular cell injury, results showed that Paricalcitol pretreatment significantly reduced cisplatin-induced cell death | PMC6989512 |
HK-2 cells | 0.5 ng/ml | 3 days | To evaluate the effect of Paricalcitol on high glucose-induced autophagy defects and inflammation. Results showed that Paricalcitol partially restored high glucose-induced autophagy defects and reduced the expression of inflammatory factors. | PMC9037529 |
Human umbilical vein endothelial cells (HUVECs) | 0.01, 0.1 or 1 µM | 30 min pretreatment followed by 6 h stimulation with TNF-α | To examine the effects of paricalcitol on TNF-α-induced expression of cell adhesion molecules. Results showed that paricalcitol suppressed the TNF-α-induced increase in ICAM-1, VCAM-1, and fractalkine expression in a dose-dependent manner. | PMC4790655 |
5363 cells | 300 nM | 36 hours | Evaluate the effect of PH combined with G on the growth inhibition of PDAC cells, results showed that GPH significantly inhibited PDAC cell growth. | PMC11866435 |
PANC-1 cells | 300 nM | 36 hours | Evaluate the effect of PH combined with G on the growth inhibition of PDAC cells, results showed that GPH significantly inhibited PDAC cell growth. | PMC11866435 |
Mia PaCa-2 cells | 300 nM | 36 hours | Evaluate the effect of PH combined with G on the growth inhibition of PDAC cells, results showed that GPH significantly inhibited PDAC cell growth. | PMC11866435 |
KPC-Luc cells | 300 nM | 36 hours | Evaluate the effect of PH combined with G on the growth inhibition of PDAC cells, results showed that GPH significantly inhibited PDAC cell growth. | PMC11866435 |
HK-2 cells | 0.1 μM | 48 hours | To evaluate the effect of PAR on HK-2 cell viability under high glucose conditions. PAR treatment significantly improved cell viability and reduced ROS generation. | PMC10933633 |
HK-2 cells | 200 nM | 72 hours | Pretreatment with paricalcitol partially restored MAMs integrity and mitochondrial function via the Mfn2-MAMs-Fundc1 pathway. | PMC10850784 |
Mouse kidney pericytes | 20 ng/mL | 90 min pretreatment followed by exposure to TGF-β1 or hypoxia for 48 h | To evaluate the protective effect of paricalcitol on TGF-β1 or hypoxia-induced pericyte injury. Results showed that paricalcitol reversed the upregulation of α-SMA, fibronectin, vimentin, and MMP-9 induced by TGF-β1 or hypoxia and restored PDGFRβ expression. | PMC8472327 |
In Vivo:
Administration | Dosage | Frequency | Description | References |
Db/db mice | Diabetic nephropathy model | Intraperitoneal injection | 0.1 μg/kg | Once daily for 10 weeks | To evaluate the effect of PAR on renal function in diabetic nephropathy mice. PAR treatment significantly attenuated kidney hypertrophy and albuminuria excretion, and improved blood glucose levels. | PMC10933633 |
C57BL/6 mice | LPS-induced myocardial inflammation model | Intraperitoneal injection | 0.2 µg/kg | Once daily for 5 days | To investigate the effects of paricalcitol on LPS-induced myocardial inflammation. Results showed that paricalcitol pre-treatment significantly suppressed LPS-induced increases in myocardial ICAM-1, VCAM-1, and TNF-α expression and alleviated myocardial microvascular leakage. | PMC4790655 |
C57BL/6 mice | Cisplatin-induced acute kidney injury model | Intraperitoneal injection | 0.2 μg/kg | Once daily for five consecutive days | To investigate the protective effect of Paricalcitol on cisplatin-induced acute kidney injury, results showed that Paricalcitol pretreatment significantly improved renal function and attenuated tissue injury | PMC6989512 |
C57BL/6 mice | Cisplatin-induced acute kidney injury model | Injection | 0.2 μg/kg | Once daily for nine days | Paricalcitol significantly improved renal function in mice, reduced inflammatory cell infiltration and mitochondrial damage in renal tissue, and suppressed oxidative stress and inflammation via the Nrf2/HO-1 signaling pathway. | PMC9861387 |
Rats | Diabetic nephropathy model | Intraperitoneal injection | 0.25 mg/kg/day | 5 times/week for 8 weeks | To evaluate the renoprotective effects of Paricalcitol alone or in combination with omega-3 fatty acids against diabetic nephropathy. Results showed that Paricalcitol monotherapy improved glycemic control, lipid profile, and renal function, reduced renal oxidative stress and inflammation, while the combination therapy exhibited enhanced renoprotective effects. | PMC9091913 |
C57BL/6J male mice | PDAC orthotopic model | Intravenous injection | 0.3 mg/kg | Twice weekly for 14 days | Evaluate the effect of GPH on tumor growth in PDAC orthotopic models, results showed that GPH significantly reduced tumor growth and improved survival. | PMC11866435 |
Mice | Ischemia-reperfusion induced acute kidney injury model | Intraperitoneal injection | 0.3 μg/kg | Injected one time at 1 day before the injury | Paricalcitol, as a clinically used activator for PGE2 synthesis, alleviated injury-induced AKI/AKI-CKD stages and eliminated the worst outcomes observed in ApelaKsp KO mice when used alone or in combination with nor-NOHA. | PMC10283061 |
Mice | Streptozotocin-induced diabetic model | Intraperitoneal injection | 0.4 µg/kg | Three times a week for 12 weeks | To evaluate the effect of Paricalcitol on the progression of diabetic nephropathy. Results showed that Paricalcitol alleviated STZ-induced albuminuria, renal tubule injury, and inflammation, and partially restored autophagy defects. | PMC9037529 |
APP/PS1 transgenic mice | Alzheimer's disease model | Intraperitoneal injection | 200 ng/kg | Once every two days for 15 weeks | To evaluate the effect of Paricalcitol on cognitive ability and Aβ generation in APP/PS1 mice. Results showed that long-term Paricalcitol treatment significantly reduced Aβ generation and neuronal loss and improved cognitive ability in mice. | PMC6642335 |
Sprague-Dawley rats | Adriamycin-induced nephropathy model | Subcutaneous osmotic pump | 6 ng/day | Once daily for 27 days | To evaluate the effect of paricalcitol on renal endothelial toxicity in a model of CKD induced by ADR in rats and explore mechanisms involved in endothelial cell maintenance. Results showed that paricalcitol improved renal function and structure through antiproteinuric effects and glomerular and tubular protection. | PMC9783872 |
Rats | Endothelial denudation-induced intimal hyperplasia | Intraperitoneal | 750 ng/kg | Every other day for 2 weeks | Paricalcitol significantly suppressed the stress response and inflammatory features induced by endothelial injury but had a limited impact on intimal hyperplasia and luminal stenosis. | PMC11084681 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT01204528 | Chronic Kidney Disease | PHASE2|PHASE3 | COMPLETED | 2025-07-13 | Karolinska Institute at Dander... More >>yd University Hospital, Danderyd, Stockholm, 18288, Sweden Less << |
NCT02018133 | CKD Stage 3/4 | Phase 3 | Completed | - | United States, Illinois ... More >> University of Illinois at Chicago Chicago, Illinois, United States, 60612 Less << |
NCT03138720 | Resectable Pancreatic Cancer ... More >> Unresectable Pancreatic Cancer Pancreatic Adenocarcinoma Less << | Phase 2 | Recruiting | March 1, 2020 | United States, Arizona ... More >> HonorHealth Research Institute Recruiting Scottsdale, Arizona, United States, 85258 Contact: Joyce Schaffer, MSN, AOCNS 480-323-1339 ext option #2 Joyce.Schaffer@HonorHealth.com Principal Investigator: Erkut Borazanci, MD Less << |
NCT00073710 | Secondary Hyperparathyroidism ... More >> Chronic Kidney Disease Less << | Phase 4 | Completed | - | United States, Nebraska ... More >> Creighton University Omaha, Nebraska, United States, 68131 Less << |
NCT00656032 | End Stage Renal Disease | Phase 2 | Completed | - | United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less << |
NCT00091481 | Kidney Failure, Chronic | PHASE4 | COMPLETED | - | Errikos Dynan Hospital, Ambelo... More >>kipi, Athens, 11526, Greece|General Hospital of Athens, "G.Gennimatas", Holargos, Athens, 11527, Greece|General Hospital of Attica "Sismanoglio", Marousi, Athens, 15126, Greece|"Hygeia" Diagnosis and Therapy Center, Marousi, Athens, 152 00, Greece|General Hospital of Melissia "Amalia Fleming", Melissia, Athens, 15127, Greece|General Hospital of Voula Askilpieion, Voula, Athens, 16673, Greece|General Hospital of Heraklion, Voutes, Heraklion, Crete, Greece|General Hospital Thessaloniki "Papanikolaou", Exohi, Thessaloniki, 570 10, Greece|General Hospital of Veria, Papagou Area, Veria, Greece|Blue Cross Clinic, Athens, 11528, Greece|Evgenidio Clinic, Athens, 11528, Greece|Regional General Hospital of Athens "Korgialeneio-Benakeio", Athens, Greece|General University Hospital of Alexandroupolis, Dragana, 68100, Greece|Regional General Hospital of Ioannina "Hatzikosta", Ioannina, 450 01, Greece|General University Hospital Ioannina, Ioannina, 455 00, Greece|General Hospital of Nikea "Agios Panteleimon", Nikea, Piraeus 18454,, Greece|General Hospital of Thessaloniki "Ahepa", Thessaloniki, Greece|General Hospital of Thessaloniki "Hippokrateion", Thessaloniki, Greece|General Hospital of Thessaloniki "Papageorgiou", Thessaloniki, Greece Less << |
NCT02754726 | Untreated Metastatic Pancreati... More >>c Ductal Adenocarcinoma Less << | Phase 2 | Recruiting | July 2020 | United States, Arizona ... More >> HonorHealth Research Institute Recruiting Scottsdale, Arizona, United States, 85258 Contact: Joyce Schaffer, MSN, AOCNS 480-323-1339 ext option #2 Joyce.Schaffer@HonorHealth.com Principal Investigator: Erkut Borazanci, MD Less << |
NCT00062699 | End-Stage Kidney Disease | Phase 4 | Terminated | - | - |
NCT01401478 | - | Completed | - | Russian Federation ... More >> Site Reference ID/Investigator# 57348 Almetyevsk, Russian Federation, 423450 Site Reference ID/Investigator# 57347 Cheboksary, Russian Federation, 428018 Site Reference ID/Investigator# 58347 Chelyabinsk, Russian Federation, 454076 Site Reference ID/Investigator# 67404 Iakutsk, Russian Federation, 677019 Site Reference ID/Investigator# 57344 Irkutsk, Russian Federation, 664079 RF Site Reference ID/Investigator# 57346 Kazan, Russian Federation, 420045 Site Reference ID/Investigator# 58356 Moscow, Russian Federation, 125284 Site Reference ID/Investigator# 58348 Moscow, Russian Federation, 127015 Site Reference ID/Investigator# 57342 Novosibirsk, Russian Federation, 630120 Site Reference ID/Investigator# 57364 Orenburg, Russian Federation, 460040 Site Reference ID/Investigator# 69687 Samara, Russian Federation, 443095 Site Reference ID/Investigator# 57363 St. Petersburg, Russian Federation, 191104 Site Reference ID/Investigator# 69688 Ulan-Ude, Russian Federation, 670031 Less << | |
NCT00091975 | Kidney Disease | Phase 3 | Completed | - | United States, California ... More >> California Institute of Renal Research San Diego, California, United States, 92120 United States, District of Columbia Georgetown University Medical Center Washington, District of Columbia, United States, 60057 United States, Florida Associates in Nephrology Fort Meyers, Florida, United States, 33908 University of Florida Gainesville, Florida, United States, 32610 Outcomes Research International, Inc. Hudson, Florida, United States, 34667 United States, Illinois Evanston Northwestern Healthcare Evanston, Illinois, United States, 60201 United States, Indiana Indiana University School of Medicine Indianapolis, Indiana, United States, 46202 United States, Louisiana Tulane University School of Medicine New Orleans, Louisiana, United States, 70112-2699 United States, Missouri Washington University Medical Center St. Louis, Missouri, United States, 63108 St. Louis University St. Louis, Missouri, United States, 63110 United States, Nevada Nea Research Las Vegas, Nevada, United States, 89102 United States, Ohio University of Cincinnati College of Medicine Cincinnati, Ohio, United States, 45267-0585 United States, Oregon Northwestern Renal Clinic, INC. Portland, Oregon, United States, 97210 United States, Tennessee Nephrology Associates, P.C. Nashville, Tennessee, United States, 37205 United States, Texas Kidney Associates, PLLC Houston, Texas, United States, 77030 University of Texas Health Center at San Antonio San Antonio, Texas, United States, 78229 Less << |
NCT00053378 | Hypocalcemia | Phase 2 | Completed | - | United States, California ... More >> Merced Heart Association Merced, California, United States, 95340 United States, Colorado Denver Health Medical Center Denver, Colorado, United States, 80204 United States, Florida Outcomes Research Institute Hudson, Florida, United States, 34667 Florida Hospital Orlando, Florida, United States, 32803 United States, Illinois University of Chicago Chicago, Illinois, United States, 60637 United States, Kentucky Central Baptist Hospital Clinical Research Center Lexington, Kentucky, United States, 40503 United States, New York Strong Memorial Hospital Rochester, New York, United States, 14642 United States, Pennsylvania St. Luke's Hospital Bethlehem, Pennsylvania, United States, 18015 United States, Virginia Heart Care Associates Hopewell, Virginia, United States, 23860 Less << |
NCT00257920 | - | Completed | - | - | |
NCT00257920 | Chronic Kidney Disease, Stage ... More >>5 Secondary Hyperparathyroidism Less << | Phase 4 | Completed | - | United States, Nebraska ... More >> Bellevue, Nebraska, United States, 68123 Omaha, Nebraska, United States, 68131 Less << |
NCT01136564 | Chronic Kidney Disease | Phase 2 | Completed | - | Denmark ... More >> Department of Medical Research Holstebro, Denmark, 7500 Less << |
NCT00053547 | Secondary Hyperparathyroidism ... More >> End Stage Renal Disease Less << | Phase 4 | Completed | - | United States, California ... More >> Stanford University Medical Center Stanford, California, United States, 94305 United States, Florida Miami Children's Hospital Miami, Florida, United States United States, New York The Children's Hospital of Buffalo Buffalo, New York, United States United States, Texas Texas Children's Hospital Houston, Texas, United States University of Texas at Houston Houston, Texas, United States United States, Wisconsin Medical College of Wisconsin Milwaukee, Wisconsin, United States Less << |
NCT01368042 | - | Completed | - | Greece ... More >> Site Reference ID/Investigator# 56803 Arta, Greece, 47100 Site Reference ID/Investigator# 53424 Athens, Greece, 11528 Site Reference ID/Investigator# 53425 Larissa, Greece, 41223 Site Reference ID/Investigator# 56805 Lefkada, Greece, 31100 Site Reference ID/Investigator# 56802 Melissia, Greece, 151 27 Site Reference ID/Investigator# 66291 Patras, Greece, 26225 Site Reference ID/Investigator# 56809 Patras, Greece, 26504 Site Reference ID/Investigator# 50442 Pylaia Thessaloniki, Greece, 57001 Site Reference ID/Investigator# 77554 Thessaloniki, Greece, 570 01, Site Reference ID/Investigator# 77553 Thessaloniki, Greece, 570 19 Site Reference ID/Investigator# 53422 Volos, Greece, 38221 Less << | |
NCT00634582 | Metastatic Cancer ... More >> Prostate Cancer Less << | Phase 2 | Terminated(slow accrual) | - | United States, North Carolina ... More >> Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 Less << |
NCT01368042 | - | Completed | - | - | |
NCT00048438 | Renal Insufficiency, Chronic | Phase 3 | Completed | - | United States, California ... More >> UCI Medical Center Orange, California, United States, 92868 United States, Colorado Western Nephrology Thornton, Colorado, United States, 80260 United States, Florida Outcomes Research International, Inc. Hudson, Florida, United States, 34667 Nephrology Association of South Miami Miami, Florida, United States, 33173 Tampa Bay Nephrology Associates Tampa, Florida, United States, 33603 United States, Illinois Northwestern University Medical School Chicago, Illinois, United States, 60611 United States, Missouri University of Missouri Health Sciences Center Columbia, Missouri, United States, 65212 Arms, Dodge, Robinson, Wilber and Crouch Kansas City, Missouri, United States, 64111 Washington University School of Medicine St. Louis, Missouri, United States, 63110 United States, Nevada NEA Research Las Vegas, Nevada, United States, 89102 United States, New York North Shore University Hospital Great Neck, New York, United States, 11021 Mount Sinai School of Medicine New York, New York, United States, 10029 United States, North Carolina Wake Nephrology Associates, PA Raleigh, North Carolina, United States, 27609 United States, Ohio Kidney and Hypertension Center Cincinnati, Ohio, United States, 45220 United States, South Carolina Dorn VA Hospital Columbia, South Carolina, United States, 29209 United States, Texas Dallas Nephrology Associates Dallas, Texas, United States, 75235 United States, Washington The Vancouver Clinic, Inc., P.S. Vancouver, Washington, United States, 98644 Poland Jagiellonian University Cracow, Poland Less << |
NCT01401478 | - | Completed | - | - | |
NCT00634582 | - | Terminated(slow accrual) | - | - | |
NCT00048516 | Renal Insufficiency, Chronic | Phase 3 | Completed | - | United States, California ... More >> VA Greater Los Angeles Healthcare System, West Los Angeles Los Angeles, California, United States, 90073 Nephrology Associates Medical Group Riverside, California, United States, 92501 Kidney Center, Inc. Simi Valley, California, United States, 93065 United States, Colorado Denver Nephrologists Denver, Colorado, United States, 80220 University of CO Health Sciences Center Denver, Colorado, United States, 80262 United States, Iowa Dialysis PC Des Moines, Iowa, United States, 50309 United States, Minnesota Twin Cities Clinical Research Arden Hills, Minnesota, United States, 55126 United States, New York Long Island College Hospital Brooklyn, New York, United States, 11201 Erie County Medical Center Buffalo, New York, United States, 14215 United States, Pennsylvania Temple University Hospital Philadelphia, Pennsylvania, United States, 19140 United States, South Carolina Medical University of South Carolina Charleston, South Carolina, United States, 29425 United States, South Dakota Avera McKennan Research Institute Sioux Falls, South Dakota, United States, 57105 United States, Tennessee Nephrology Associates Nashville, Tennessee, United States, 37205 United States, Texas San Antonio Kidney Disease Research Center San Antonio, Texas, United States, 78219 United States, Virginia Clinical Research Associates of Tidewater Norfolk, Virginia, United States, 23507 United States, Washington FHS Research Center Tacoma, Washington, United States, 98405 Poland Wojewodzki Szpital Specjalistyczny AM w Bialymstoku Bialymstoku, Poland Krakow Hospital Krakow, Poland Less << |
NCT01224782 | - | Completed | - | - | |
NCT00048451 | Renal Insufficiency, Chronic | Phase 3 | Completed | - | United States, Arizona ... More >> Tucson Therapeutic Research Institute, Inc. Tucson, Arizona, United States, 85712 United States, California Pasadena, California, United States, 91105 California Institute of Renal Research San Diego, California, United States, 92120 Nephrology Educational Services and Research, Inc. Tarzana, California, United States, 91356 United States, Connecticut Phoenix Internal Medicine Associates Waterbury, Connecticut, United States, 06708 United States, Florida University of Florida Gainesville, Florida, United States, 32610 Miami Kidney Group Miami, Florida, United States, 33143 ICSL Clinical Studies Sarasota, Florida, United States, 34232 Genesis Clinical Research Corporation Tampa, Florida, United States, 33614 United States, Illinois Evanston Northwestern Healthcare Evanston, Illinois, United States, 60201 United States, Indiana Medisphere Medical Research Center Evansville, Indiana, United States, 47714 United States, Louisiana Ochsner Clinic Chronic Dialysis New Orleans, Louisiana, United States, 70121 United States, Maryland Biolab Research, LLC Rockville, Maryland, United States, 20852 United States, New York The Rogosin Institute New York, New York, United States, 10021 United States, Ohio Dialysis Clinic, Inc. Cincinnati, Ohio, United States, 45206 United States, Texas Kidney Associates Houston, Texas, United States, 77030 Texas Tech University Health Science Center Lubbock, Texas, United States, 79430 University of Texas Health Science Center San Antonio, Texas, United States, 78229 Poland Wojskowy Instytut Medyczny Warszawa, Poland Less << |
NCT01506947 | - | Completed | - | - | |
NCT01506947 | Moderate to Severe Secondary H... More >>yperparathyroidism Stage 5 Chronic Kidney Diseases Less << | Phase 4 | Completed | - | - |
NCT00958451 | Secondary Hyperparathyroidism ... More >> Chronic Kidney Disease Less << | Phase 4 | Completed | - | United States, Virginia ... More >> VA Medical Center Salem, Virginia, United States, 24153 Less << |
NCT01081665 | - | Completed | - | Greece ... More >> Site Reference ID/Investigator# 32055 Athens, Greece, 11526 Site Reference ID/Investigator# 32050 Athens, Greece, 11528 Site Reference ID/Investigator# 32051 Athens, Greece, 11528 Site Reference ID/Investigator# 32049 Athens, Greece, 17237 Site Reference ID/Investigator# 5283 Athens, Greece Site Reference ID/Investigator# 32056 Chalkida, Greece, 34100 Site Reference ID/Investigator# 32057 Chania, Greece, 73100 Site Reference ID/Investigator# 32058 Drama, Greece, 66100 Site Reference ID/Investigator# 32077 Holargos, Greece, 15562 Site Reference ID/Investigator# 32076 Katerini, Greece, 60100 Site Reference ID/Investigator# 32059 Kavala, Greece, 65201 Site Reference ID/Investigator# 32053 Komotini, Greece, 69100 Site Reference ID/Investigator# 32060 Lamia, Greece, 35100 Site Reference ID/Investigator# 32061 Lefkada, Greece, 31100 Site Reference ID/Investigator# 32062 Livadia, Greece, 32100 Site Reference ID/Investigator# 32048 Pireus, Greece Site Reference ID/Investigator# 32054 Preveza, Greece, 48100 Site Reference ID/Investigator# 32063 Ptolemaida, Greece, 50200 Site Reference ID/Investigator# 32075 Volos, Greece, 38222 Less << | |
NCT03519308 | Pancreatic Cancer | Early Phase 1 | Recruiting | August 4, 2019 | United States, Pennsylvania ... More >> Abramson Cancer Center of the University of Pennsylvania Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Peter O'Dwyer, MD 855-216-0098 PennCancerTrials@emergingmed.com Principal Investigator: Peter O'Dwyer, MD Less << |
NCT01081665 | - | Completed | - | - | |
NCT00463021 | Secondary Hyperparathyroidism | Phase 4 | Completed | - | United States, California ... More >> Downey, California, United States Paramount, California, United States United States, Florida Hudson, Florida, United States United States, Georgia Augusta, Georgia, United States Decatur, Georgia, United States United States, Pennsylvania Pittsburgh, Pennsylvania, United States United States, Tennessee Nashville, Tennessee, United States United States, Virginia Norfolk, Virginia, United States Less << |
NCT00454350 | Secondary Hyperparathyroidism | Phase 4 | Completed | - | United States, Minnesota ... More >> Minneapolis, Minnesota, United States Less << |
NCT01224782 | - | Completed | - | - | |
NCT01012414 | Coronary Artery Disease ... More >> Chronic Kidney Disease Hypovitaminosis D Secondary Hyperparathyroidism Less << | Phase 3 | Terminated(Futility in enrollm... More >>ent as of May 31, 2011) Less << | - | United States, Pennsylvania ... More >> Thomas Jefferson University Philadelphia, Pennsylvania, United States, 19107 Less << |
NCT00258258 | Multiple Myeloma and Plasma Ce... More >>ll Neoplasm Less << | Phase 1 | Terminated(Withdrawn due to lo... More >>w accrual) Less << | - | United States, New York ... More >> Roswell Park Cancer Institute Buffalo, New York, United States, 14263-0001 Less << |
NCT01012414 | - | Terminated(Futility in enrollm... More >>ent as of May 31, 2011) Less << | - | - | |
NCT02030860 | Previously Untreated Resectabl... More >>e Adenocarcinoma of the Pancreas Less << | Not Applicable | Active, not recruiting | - | United States, Pennsylvania ... More >> Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Less << |
NCT03588884 | Secondary Hyperparathyroidism ... More >>Due to Renal Causes Vitamin D Deficiency CKD Stage 3 CKD Stage 4 Less << | Phase 4 | Recruiting | December 4, 2018 | United States, Wisconsin ... More >> Spaulding Clinical Research Recruiting West Bend, Wisconsin, United States, 53095 Contact: Randy Spaulding 262-206-3085 Randy.Spaulding@spauldingclinical.com Contact: Laura Millard 262-306-3362 Laura.Millard@spauldingclinical.com Principal Investigator: Carlos Sanabria, MD Less << |
NCT01680198 | Chronic Kidney Disease. | Phase 3 | Completed | - | Italy ... More >> Nephrology, Dialysis and Transplantation Unit Reggio Calabria, Italy, 89124 Less << |
NCT02686827 | Hypersensitivity | Phase 2 | Completed | - | Netherlands ... More >> Academic medical center Amsterdam, Netherlands, 1100 AZ Less << |
NCT01083186 | - | Completed | - | Greece ... More >> Site Reference ID/Investigator# 47002 Arta, Greece, 47100 Site Reference ID/Investigator# 43772 Athens, Greece, 115 21 Site Reference ID/Investigator# 27492 Athens, Greece, 115 27 Site Reference ID/Investigator# 43769 Athens, Greece, 115 27 Site Reference ID/Investigator# 38257 Athens, Greece, 11526 Site Reference ID/Investigator# 47003 Athens, Greece, 11526 Site Reference ID/Investigator# 27497 Athens, Greece, 11527 Site Reference ID/Investigator# 47004 Athens, Greece, 11527 Site Reference ID/Investigator# 27489 Athens, Greece, 11528 Site Reference ID/Investigator# 27495 Athens, Greece, 16673 Site Reference ID/Investigator# 43773 Athens, Greece, 17237 Site Reference ID/Investigator# 27498 Haidari, Athens, Greece, 12462 Site Reference ID/Investigator# 38259 Ioannina, Greece, 45500 Site Reference ID/Investigator# 22121 Larissa, Greece, 411 10 Site Reference ID/Investigator# 43771 Larissa, Greece, 41223 Site Reference ID/Investigator# 43767 Maroussi Athens, Greece, 15123 Site Reference ID/Investigator# 27496 Nikaia, Greece, 18454 Site Reference ID/Investigator# 43768 North Ionia, Athens, Greece, 142 33 Site Reference ID/Investigator# 27491 Piraeus, Greece, 18536 Site Reference ID/Investigator# 27494 Thessaloniki, Greece, 546 36 Site Reference ID/Investigator# 27493 Thessaloniki, Greece, 54636 Site Reference ID/Investigator# 38255 Thessaloniki, Greece, 56403 Site Reference ID/Investigator# 43770 Thessaloniki, Greece, 570 01 Site Reference ID/Investigator# 39839 Thessaloniki, Greece Less << | |
NCT00469625 | Proteinuric Renal Disease | Not Applicable | Withdrawn(Investigator left th... More >>e Institution.) Less << | - | United States, New York ... More >> Winthrop Univ. Hospital Mineola, New York, United States, 11501 Less << |
NCT00307840 | Secondary Hyperparathyroidism | Phase 4 | Completed | - | - |
NCT01265992 | - | Completed | - | Sweden ... More >> Site Reference ID/Investigator# 47723 Kalmar, Sweden, 391 85 Site Reference ID/Investigator# 41084 Karlstad, Sweden, 651 85 Site Reference ID/Investigator# 45190 Kristianstad, Sweden, 291 85 Site Reference ID/Investigator# 41085 Linkoping, Sweden, 581 85 Site Reference ID/Investigator# 41087 Norrkoping, Sweden, 601 82 Site Reference ID/Investigator# 45188 Orebro, Sweden, 701 85 Site Reference ID/Investigator# 41088 Skovde, Sweden, 541 85 Site Reference ID/Investigator# 57782 Stockholm, Sweden, 112 81 Site Reference ID/Investigator# 41089 Varnamo, Sweden, 331 85 Site Reference ID/Investigator# 45191 Vasteras, Sweden, 721 89 Less << | |
NCT02011828 | Inflammation ... More >>Insulin Resistance Less << | Phase 1 | Completed | - | United States, Utah ... More >> University of Utah Salt Lake City, Utah, United States, 84112 Less << |
NCT01758289 | - | Terminated(Changes in country ... More >>regulation) Less << | - | Venezuela ... More >> Site Reference ID/Investigator# 96757 Acarigua, Venezuela Site Reference ID/Investigator# 96766 Barquisimeto, Venezuela Site Reference ID/Investigator# 96768 Caracas, Venezuela Site Reference ID/Investigator# 96760 Maracaibo, Venezuela Site Reference ID/Investigator# 96761 Maracaibo, Venezuela Site Reference ID/Investigator# 96770 Miranda, Venezuela Site Reference ID/Investigator# 96763 Monagas, Venezuela Site Reference ID/Investigator# 96765 Naguanagua, Venezuela Less << | |
NCT01265992 | - | Completed | - | - | |
NCT01820078 | Chronic Kidney Disease, Unspec... More >>ified Less << | Phase 4 | Terminated(Recruitment not rea... More >>ched) Less << | December 2013 | Spain ... More >> Hospital Germans Trias i Pujol Badalona, Barcelona, Spain, 08035 Hospital Son Espases Mallorca, Islas Baleares, Spain, 07010 Hospital Virgen de la Candelaria Santa Cruz de Tenerife, Islas Canarias, Spain, 38010 Hospital Comarcal Da Costa Burela, Lugo, Spain, 27880 Hosp. U. Fundación de Alcorcón Alcorcón, Madrid, Spain, 28922 Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, 28222 Hospital Infanta Sofía San Sebastian de los Reyes, Madrid, Spain, 28702 Hospital de Galdakao Bilbao, País Vasco, Spain, 48960 Hospital Universitario General de Alicante Alicante, Spain, 03010 Fundació Puigvert Barcelona, Spain, 08025 Hospital Valle de Hebrón Barcelona, Spain, 08035 Hospital Reina Sofía Córdoba, Spain, 14004 Hospital Virgen de las Nieves Granada, Spain, 18014 Hospital Gregorio Marañon Madrid, Spain, 28007 Hospital Ramon y Cajal Madrid, Spain, 28034 Clínico San Carlos Madrid, Spain, 28040 Fundación Jiménez Díaz Madrid, Spain, 28040 Hospital 12 de Octubre Madrid, Spain, 28046 Hospital Universitario La Paz Madrid, Spain, 28046 Hospital Carlos Haya Málaga, Spain, 29010 Hospital Universitario Virgen de la Macarena Sevilla, Spain, 41009 Hospital Universitario Virgen del Rocío Sevilla, Spain, 41013 Hospital General Universitario de Valencia Valencia, Spain, 46014 Hospital Dr Peset Valencia, Spain, 46017 Hospital Clinico Lozano Blesa Zaragoza, Spain, 50009 Less << |
NCT01134315 | - | Terminated(Terminated after FD... More >>A agreement.) Less << | - | United States, Alabama ... More >> Site Reference ID/Investigator# 37082 Birmingham, Alabama, United States, 35255 United States, Florida Site Reference ID/Investigator# 26762 Gainesville, Florida, United States, 32610 Site Reference ID/Investigator# 28529 Orlando, Florida, United States, 32801 United States, Georgia Site Reference ID/Investigator# 26748 Atlanta, Georgia, United States, 30322 United States, Louisiana Site Reference ID/Investigator# 37582 New Orleans, Louisiana, United States, 70118 United States, Maryland Site Reference ID/Investigator# 39973 Baltimore, Maryland, United States, 21287 United States, Massachusetts Site Reference ID/Investigator# 26769 Boston, Massachusetts, United States, 02115 United States, Michigan Site Reference ID/Investigator# 26768 Detroit, Michigan, United States, 48201 United States, Missouri Site Reference ID/Investigator# 26747 Kansas City, Missouri, United States, 64108 United States, Ohio Site Reference ID/Investigator# 26749 Akron, Ohio, United States, 44308 Site Reference ID/Investigator# 26751 Cincinnati, Ohio, United States, 45229 Site Reference ID/Investigator# 26765 Columbus, Ohio, United States, 43205 United States, Oklahoma Site Reference ID/Investigator# 28528 Oklahoma City, Oklahoma, United States, 73104 United States, Oregon Site Reference ID/Investigator# 26763 Portland, Oregon, United States, 97227 United States, Virginia Site Reference ID/Investigator# 28526 Charlottesville, Virginia, United States, 22908 United States, Washington Site Reference ID/Investigator# 26758 Seattle, Washington, United States, 98105 United States, Wisconsin Site Reference ID/Investigator# 40382 Madison, Wisconsin, United States, 53792 Site Reference ID/Investigator# 26759 Wauwatosa, Wisconsin, United States, 53226 Less << | |
NCT00891813 | Secondary Hyperparathyroidism ... More >> Renal Insufficiency, Chronic Parathyroid Hormone Hemodialysis Hypercalcemia Less << | Phase 4 | Completed | - | Peru ... More >> Site Reference ID/Investigator# 21401 Callao, Peru, CALLAO 2 Site Reference ID/Investigator# 23857 Lima, Peru, Lima-11 Site Reference ID/Investigator# 10941 Lima, Peru Less << |
NCT01083186 | - | Completed | - | - | |
NCT00891813 | - | Completed | - | - | |
NCT01083849 | - | Completed | - | - | |
NCT00064376 | Leukemia Myel... More >>odysplastic Syndromes Less << | Phase 2 | Completed | - | United States, California ... More >> Cedars-Sinai Comprehensive Cancer Center at Cedars-Sinai Medical Center Los Angeles, California, United States, 90048 Less << |
NCT01273597 | - | Completed | - | Hungary ... More >> Site Reference ID/Investigator# 46593 Budapest, Hungary, 1083 Site Reference ID/Investigator# 46585 Budapest, Hungary, 1115 Site Reference ID/Investigator# 46594 Debrecen, Hungary, 4012 Site Reference ID/Investigator# 47722 Gyor, Hungary, 9023 Site Reference ID/Investigator# 46592 Karcag, Hungary, 5301 Site Reference ID/Investigator# 58644 Karcag, Hungary, 5301 Site Reference ID/Investigator# 46595 Miskolc, Hungary, 3501 Site Reference ID/Investigator# 46588 Nyiregyhaza, Hungary, 4400 Site Reference ID/Investigator# 46597 Pecs, Hungary, 7624 Site Reference ID/Investigator# 46590 Szombathely, Hungary, 9700 Site Reference ID/Investigator# 46591 Veszprem, Hungary, 8200 Less << | |
NCT01083849 | - | Completed | - | - | |
NCT01273597 | - | Completed | - | - | |
NCT01073462 | - | Completed | - | Austria ... More >> Site Reference ID/Investigator# 27447 Graz, Austria, 8010 Site Reference ID/Investigator# 49182 Graz, Austria, 8020 Site Reference ID/Investigator# 27483 Graz, Austria, 80360 Site Reference ID/Investigator# 52742 Graz, Austria, 8052 Site Reference ID/Investigator# 27487 Innsbruck, Austria, 6020 Site Reference ID/Investigator# 36983 Linz, Austria, 4010 Site Reference ID/Investigator# 27484 Linz, Austria, 4020 Site Reference ID/Investigator# 27485 Rottenmann, Austria, 8786 Site Reference ID/Investigator# 27446 Vienna, Austria, 1030 Site Reference ID/Investigator# 53469 Vienna, Austria, 1090 Site Reference ID/Investigator# 27482 Vienna, Austria, 1130 Site Reference ID/Investigator# 10981 Vienna, Austria, 1220 Less << | |
NCT01758289 | - | Terminated(Changes in country ... More >>regulation) Less << | - | - | |
NCT01134315 | - | Terminated(Terminated after FD... More >>A agreement.) Less << | - | - | |
NCT01073462 | - | Completed | - | - | |
NCT01265615 | - | Completed | - | - | |
NCT00646932 | Chronic Kidney Disease | Phase 2 | Completed | - | Japan ... More >> Gunma, Japan Hokkaido, Japan Ibaraki, Japan Kagoshima, Japan Kumamoto, Japan Nagano, Japan Nagasaki, Japan Saitama, Japan Shizuoka, Japan Tokyo, Japan Less << |
NCT00469599 | Secondary Hyperparathyroidism ... More >> Chronic Kidney Disease Vitamin D Deficiency Less << | Not Applicable | Terminated(Terminated after 86... More >> pt included, because of recruitment problems) Less << | - | Denmark ... More >> Aalborg University Hospital Aalborg, Denmark, 4000 Århus University Hospital Skejby Aarhus, Denmark, 4000 Hospital of Southwest Denmark Esbjerg Esbjerg, Denmark, 6700 Holbæk County Hospital Holbæk, Denmark, 4300 Holstebro County Hospital Holstebro, Denmark, 7500 Odense University Hospital Odense, Denmark, 5000 Roskilde County Hospital Roskilde, Denmark, 4000 Viborg County Hospital Viborg, Denmark, 8800 Less << |
NCT01331317 | Cardiovascular Disease|Diabeti... More >>c Nephropathy Less << | PHASE4 | COMPLETED | 2025-04-12 | Steno Diabetes Center A/S, Gen... More >>tofte, 2400, Denmark Less << |
NCT00752102 | - | Completed | - | - | |
NCT00752102 | Chronic Kidney Disease ... More >> Vitamin D Deficiency Coronary Calcification Disorders of Calcium and Bone Metabolism Less << | Phase 4 | Completed | - | United States, Pennsylvania ... More >> Hospital of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19107 Less << |
NCT01138475 | Gastric Bypass ... More >> Parathyroid Hormone Less << | Phase 3 | Completed | - | United States, Michigan ... More >> William Beaumont Health Center Royal Oak, Michigan, United States, 48073 Less << |
NCT00646035 | End Stage Renal Disease | Phase 3 | Completed | - | - |
NCT01265615 | Cardiorenal Syndrome ... More >> Chronic Allograft Nephropathy Less << | Phase 4 | Completed | - | Netherlands ... More >> De Haar Research Foundation Rotterdam, South Holland, Netherlands, 3071PR Russian Federation Ural Institute of Cardiology Yekaterinburg, Russian Federation, 620144 Less << |
NCT01138475 | - | Completed | - | - | |
NCT00417612 | Hypophosphatemia, Familial ... More >> Hyperparathyroidism Less << | Phase 3 | Completed | - | United States, Connecticut ... More >> Yale University School of Medicine New Haven, Connecticut, United States, 06520 Less << |
NCT00417612 | - | Completed | - | - | |
NCT01630408 | Heart Failure | WITHDRAWN | 2025-06-14 | Massachusetts General Hospital... More >>, Boston, Massachusetts, 01886, United States Less << | |
NCT00217477 | Unspecified Adult Solid Tumor,... More >> Protocol Specific Less << | Phase 1 | Completed | - | United States, New York ... More >> Roswell Park Cancer Institute Buffalo, New York, United States, 14263-0001 Less << |
NCT01084538 | - | Completed | - | Croatia ... More >> Site Reference ID/Investigator# 27525 Dubrovnik, Croatia, 20000 Site Reference ID/Investigator# 27531 Imotski, Croatia, 21260 Site Reference ID/Investigator# 6175 Karlovac, Croatia, 47000 Site Reference ID/Investigator# 27528 Pula, Croatia, 52100 Site Reference ID/Investigator# 27533 Rijeka, Croatia, 51000 Site Reference ID/Investigator# 27524 Sibenik, Croatia, 22000 Site Reference ID/Investigator# 27523 Sisak, Croatia, 44000 Site Reference ID/Investigator# 27529 Slavonski Brod, Croatia, 35000 Site Reference ID/Investigator# 27530 Split, Croatia, 1000 Site Reference ID/Investigator# 27534 Trogir, Croatia, 21220 Site Reference ID/Investigator# 27522 Vinkovci, Croatia, 32000 Site Reference ID/Investigator# 27527 Zadar, Croatia, 23000 Site Reference ID/Investigator# 27526 Zagreb, Croatia, 10000 Site Reference ID/Investigator# 27532 Zagreb, Croatia, 10000 Serbia Site Reference ID/Investigator# 27536 Beograd, Serbia, 11000 Site Reference ID/Investigator# 27538 Beograd, Serbia, 11000 Site Reference ID/Investigator# 27539 Beograd, Serbia, 11000 Site Reference ID/Investigator# 6169 Beograd, Serbia, 11000 Site Reference ID/Investigator# 27540 Beograd, Serbia, 11080 Site Reference ID/Investigator# 27535 Bor, Serbia, 19210 Site Reference ID/Investigator# 27537 Kragujevac, Serbia, 34000 Less << | |
NCT00823303 | Secondary Hyperparathyroidism ... More >> Chronic Kidney Disease Less << | Phase 4 | Completed | - | United States, Illinois ... More >> Northwestern University Chicago, Illinois, United States, 60611 Northshore University Health System Evanston, Illinois, United States, 60201 United States, Michigan Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, Missouri Washington University St. Louis, Missouri, United States, 63110 Less << |
NCT00667576 | Chronic Kidney Disease on Hemo... More >>dialysis Secondary Hyperparathyroidism Less << | Phase 2 | Completed | - | Japan ... More >> Tokyo, Metropolis, Japan Aichi, Prefecture, Japan Chiba, Prefecture, Japan Fukuoka, Prefecture, Japan Hokkaido, Prefecture, Japan Ibaragi, Prefecture, Japan Kanagawa, Prefecture, Japan Kumamoto, Prefecture, Japan Nagano, Prefecture, Japan Nagasaki, Prefecture, Japan Osaka, Prefecture, Japan Saitama, Prefecture, Japan Less << |
NCT00823303 | - | Completed | - | - | |
NCT01071070 | Chronic Kidney Disease | Phase 3 | Completed | - | China ... More >> Site Reference ID/Investigator# 23483 Beijing, China, 100034 Site Reference ID/Investigator# 23485 Beijing, China, 100044 Site Reference ID/Investigator# 23482 Beijing, China, 100730 Site Reference ID/Investigator# 23484 Dalian City, China, 116011 Site Reference ID/Investigator# 23486 Guangzhou City, China, 510080 Site Reference ID/Investigator# 23488 Nanjing, China, 210029 Site Reference ID/Investigator# 37722 Qingdao, China, 266003 Site Reference ID/Investigator# 23490 Shanghai, China, 200001 Site Reference ID/Investigator# 25502 Shanghai, China, 200001 Site Reference ID/Investigator# 23489 Shanghai, China, 200025 Site Reference ID/Investigator# 23487 Shanghai, China, 200092 Site Reference ID/Investigator# 35822 Wenzhou, China, 325000 Less << |
NCT01694160 | Proteinuria | PHASE3 | COMPLETED | 2025-12-15 | Renal Section, Oslo University... More >> Hospital, Rikshospitalet, Oslo, 0424, Norway Less << |
NCT01084538 | - | Completed | - | - | |
NCT03331562 | Pancreatic Cancer ... More >> Pancreas Adenocarcinoma Advanced Pancreatic Cancer Metastatic Pancreatic Cancer Metastatic Pancreatic Adenocarcinoma Less << | Phase 2 | Recruiting | December 15, 2019 | United States, Arizona ... More >> HonorHealth Research Institute Recruiting Scottsdale, Arizona, United States, 85258 Contact: Joyce Schaffer, RN 480-323-1339 clinicaltrials@honorhealth.com Principal Investigator: Erkut Borazanci, MD Principal Investigator: Gayle Jameson, ACNP-BC AOCN United States, California City of Hope National Medical Center Recruiting Duarte, California, United States, 91010 Contact: Isma Hafeez 626-218-5013 ihafeez@coh.org Principal Investigator: Vincent Chung, MD United States, New Jersey Atlantic Medical Group-Oncology Morristown Medical Center Recruiting Morristown, New Jersey, United States, 07962 Contact: Nancy Ginder, RN, BSN 973-971-6608 Principal Investigator: Angela Alistar, MD Less << |
NCT01792206 | Type 2 Diabetes ... More >> Chronic Kidney Disease Less << | Not Applicable | Unknown | February 2013 | United States, Georgia ... More >> Emory University Atlanta, Georgia, United States, 30303 United States, Louisiana Tulane University New Orleans, Louisiana, United States, 70112 United States, Massachusetts Joslin Diabetes Clinic, Inc. Boston, Massachusetts, United States, 02215 United States, Nebraska Omaha VA Medical Center Omaha, Nebraska, United States, 68105 Less << |
NCT00800358 | Hyperparathyroidism ... More >> Kidney Disease Less << | Not Applicable | Completed | - | Malaysia ... More >> Hospital Sultanah Bahiyah Haemodialysis Unit KM 6 Jalan Langgar Alor Star, Kedah, Malaysia, 05460 Hemodialysis Unit, Raja Perempuan Zainab II Hospital Kota Bahru, Kelantan, Malaysia, 15586 Hemodialysis Unit, Tengku Ampuan Afzan Hospital Kuantan, Pahang, Malaysia, 25100 Clinical Research Centre, Penang Hospital Georgetown, Penang, Malaysia, 10990 Haemodialysis Unit, Seberang Jaya Hospital Seberang jaya, Penang, Malaysia, 13700 Hemodialysis Unit, Taiping Hospital Taiping, Perak, Malaysia, 34000 Nephrology Department, Tengku Ampuan Rahimah Hospital Klang, Selangor, Malaysia, 41200 Hemodialysis Unit, Kuala Lumpur Hospital Kuala Lumpur, Selangor, Malaysia, 50586 Haemodialysis Unit, Serdang Hospital Serdang, Selangor, Malaysia, 43000 Hemodialysis Unit, Tuanku Ja'afar Seremban Hospital Seremban, Selangor, Malaysia, 70300 Haemodialysis Unit, Melaka Hospital Melaka, Malaysia, 75400 Less << |
NCT00599963 | IgA Nephropathy | Phase 3 | Withdrawn(Funding problem.) | December 2009 | Hong Kong ... More >> Department of Medicine & Therapeutics, Prince of Wales Hospital Shatin, Hong Kong Less << |
NCT01071070 | - | Completed | - | - | |
NCT00915876 | Chronic Kidney Disease | Not Applicable | Completed | - | United States, New York ... More >> Albany Medical Center South Clinical Campus Albany, New York, United States, 12208 Less << |
NCT03300921 | Pancreatic Cancer | PHASE1 | TERMINATED | 2022-03-23 | Abramson Cancer Center of the ... More >>University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States Less << |
NCT00667576 | - | Completed | - | - | |
NCT00990704 | Secondary Hyperparathyroidism ... More >> Hemodialysis Less << | Phase 2 | Completed | - | Japan ... More >> Site Ref # / Investigator 53794 Anjo, Japan Site Ref # / Investigator 53787 Chiba, Japan Site Ref # / Investigator 53786 Kumagaya, Japan Site Ref # / Investigator 53792 Matsumoto, Japan Site Ref # / Investigator 53784 Mito, Japan Site Ref # / Investigator 53796 Nagasaki, Japan Site Ref # / Investigator 53795 Osaka, Japan Site Ref # / Investigator 21561 Sapporo, Japan Site Ref # / Investigator 53789 Tokyo, Japan Site Ref # / Investigator 53790 Tokyo, Japan Site Ref # / Investigator 53793 Toyohashi, Japan Site Ref # / Investigator 53785 Tsuchiura, Japan Site Ref # / Investigator 53788 Yachiyo, Japan Site Ref # / Investigator 53791 Yokosuka, Japan Less << |
NCT00915876 | - | Completed | - | - | |
NCT00637897 | Breast Cancer | Phase 1 | Completed | - | United States, North Carolina ... More >> Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 Less << |
NCT01393808 | Type 2 Diabetes | Phase 2 | Completed | - | Italy ... More >> ASL of Ponte San Pietro - Diabetologic Unit Brembate, Bergamo, Italy, 24030 Clinical Research Center fo Rare Diseases Aldo and Cele Daccò Ranica, Bergamo, Italy, 24020 Azienda Ospedaliera di Treviglio e Caravaggio - Unit of Diabetology and Metabolic Diseases Romano di Lombardia, BG, Italy Azienda Ospedaliera Bolognini - Unità di Medicina Seriate, BG, Italy Azienda Ospedaliera di Treviglio e Caravaggio - Unit of Diabetology and Metabolic Diseases Treviglio, BG, Italy Azienda Ospedaliera Ospedali Riuniti di Bergamo Bergamo, Italy Less << |
NCT00497146 | Chronic Kidney Disease ... More >> Left Ventricular Hypertrophy Less << | Phase 3 | Completed | - | - |
NCT01341782 | Secondary Hyperparathyroidism ... More >> Hemodialysis Less << | Phase 3 | Completed | - | Japan ... More >> Site Reference ID/Investigator# 53485 Aichi, Japan Site Reference ID/Investigator# 51571 Chiba, Japan Site Reference ID/Investigator# 52963 Chiba, Japan Site Reference ID/Investigator# 52966 Chiba, Japan Site Reference ID/Investigator# 51578 Gifu, Japan Site Reference ID/Investigator# 52965 Gunma, Japan Site Reference ID/Investigator# 53782 Hadano-City, Japan Site Reference ID/Investigator# 57483 Himeji-City, Japan Site Reference ID/Investigator# 57487 Hokkaido, Japan Site Reference ID/Investigator# 53484 Hyogo, Japan Site Reference ID/Investigator# 54385 Ibaraki, Japan Site Reference ID/Investigator# 51581 Kagawa, Japan Site Reference ID/Investigator# 59164 Kagoshima, Japan Site Reference ID/Investigator# 51574 Kanagawa, Japan Site Reference ID/Investigator# 51575 Kanagawa, Japan Site Reference ID/Investigator# 52751 Kodaira, Japan Site Reference ID/Investigator# 62025 Koga, Japan Site Reference ID/Investigator# 54384 Matsumoto, Japan Site Reference ID/Investigator# 52745 Midori, Japan Site Reference ID/Investigator# 51569 Mito, Japan Site Reference ID/Investigator# 52964 Nagano, Japan Site Reference ID/Investigator# 53483 Nagano, Japan Site Reference ID/Investigator# 51582 Nagasaki, Japan Site Reference ID/Investigator# 54388 Nagoya, Japan Site Reference ID/Investigator# 51576 Niigata, Japan Site Reference ID/Investigator# 51577 Niigata, Japan Site Reference ID/Investigator# 51580 Osaka, Japan Site Reference ID/Investigator# 52747 Osaka, Japan Site Reference ID/Investigator# 52748 Osaka, Japan Site Reference ID/Investigator# 52750 Osaka, Japan Site Reference ID/Investigator# 51570 Saitama, Japan Site Reference ID/Investigator# 54387 Sakai, Japan Site Reference ID/Investigator# 52746 Sapporo, Japan Site Reference ID/Investigator# 51579 Shizuoka, Japan Site Reference ID/Investigator# 62024 Takasaki, Japan Site Reference ID/Investigator# 51572 Tokyo, Japan Site Reference ID/Investigator# 52752 Tokyo, Japan Site Reference ID/Investigator# 53482 Tokyo, Japan Site Reference ID/Investigator# 59162 Tokyo, Japan Site Reference ID/Investigator# 59966 Tokyo, Japan Site Reference ID/Investigator# 53783 Tomakomai-shi, Japan Site Reference ID/Investigator# 54383 Toyama, Japan Site Reference ID/Investigator# 52749 Wakayama, Japan Site Reference ID/Investigator# 52962 Yachiyoshi, Japan Site Reference ID/Investigator# 59163 Yokohama-Shi, Japan Less << |
NCT00990704 | - | Completed | - | - | |
NCT00664430 | Secondary Hyperparathyroidism ... More >> Dialysis Less << | Phase 4 | Terminated(Low enrollment rate... More >>) Less << | - | Brazil ... More >> Site Reference ID/Investigator# 7118 Sao Paulo, Brazil, 04039-001 Site Reference ID/Investigator# 7114 Sao Paulo, Brazil, 05403-000 Less << |
NCT00664430 | - | Terminated(Low enrollment rate... More >>) Less << | - | - | |
NCT00587158 | Transplant; Failure, Kidney ... More >> Renal Disease, End Stage Hyperparathyroidism, Secondary Less << | Not Applicable | Completed | - | United States, Arizona ... More >> Mayo Clinic Scottsdale, Arizona, United States, 85259 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 Less << |
NCT00497146 | - | Completed | - | - | |
NCT00587158 | - | Completed | - | - | |
NCT01820767 | Chronic Kidney Disease | Phase 3 | Completed | - | Spain ... More >> Hospital El Bierzo. Servicio de Nefrología. Ponferrada, (León)., Spain, 24411, Hospital de León León, Spain, 24008 Less << |
NCT00294866 | Kidney Failure | PHASE4 | COMPLETED | 2025-01-08 | Southwest Nephrology, Evergree... More >>n Park, Illinois, 60805, United States|Nephrology Center, Kalamazoo, Michigan, 49007, United States|Nephrology Associates P.A., West Orange, New Jersey, 07052, United States|Delaware Valley Nephrology, Philadelphia, Pennsylvania, 19144, United States|Nephrology Associates, PC, Nashville, Tennessee, 37205, United States|Tyler Nephrology Associates, Tyler, Texas, 75701, United States Less << |
NCT00977080 | Chronic Kidney Disease ... More >> Secondary Hyperparathyroidism Hemodialysis Less << | Phase 4 | Completed | - | - |
NCT00796679 | Chronic Kidney Disease | Not Applicable | Completed | - | Hong Kong ... More >> Queen Mary Hospital Hong Kong, Hong Kong, 0000 University of Hong Kong, Queen Mary Hospital Hong Kong, Hong Kong, 0000 Less << |
NCT03415854 | Pancreatic Cancer ... More >> Pancreatic Ductal Adenocarcinoma Pancreatic Adenocarcinoma Pancreas Metastases Adenocarcinoma Less << | Phase 2 | Recruiting | December 15, 2020 | United States, Arizona ... More >> HonorHealth Research Institute Recruiting Scottsdale, Arizona, United States, 85258 Contact: Joyce Schaffer, MSN, AOCNS 480-323-1339 ext option #2 Joyce.Schaffer@HonorHealth.com Principal Investigator: Erkut Borazanci, MD Less << |
NCT01341782 | - | Completed | - | - | |
NCT01436747 | Disorder of Transplanted Kidne... More >>y Proteinuria Albuminuria Less << | Phase 3 | Completed | - | Slovenia ... More >> University Medical Centre Ljubljana Ljubljana, Slovenia, 1000 Less << |
NCT01197664 | Mucinous Adenocarcinoma of the... More >> Rectum Stage IIA Rectal Cancer Stage IIB Rectal Cancer Stage IIC Rectal Cancer Stage IIIB Rectal Cancer Stage IIIC Rectal Cancer Less << | Phase 1 | Terminated(Study terminated du... More >>e to funding issues) Less << | - | United States, North Carolina ... More >> Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 Less << |
NCT00977080 | - | Completed | - | - | |
NCT00421733 | - | Completed | - | - | |
NCT01725113 | Kidney Failure ... More >> Secondary Hyperparathyroidism Hyperphosphatemia Hypercalcemia Less << | Phase 4 | Terminated(Nationwide shortage... More >> of study meds in 2013 loss of funding & competing studies) Less << | - | United States, New York ... More >> Winthrop University Hospital Mineola, New York, United States, 11501 Less << |
NCT03520790 | Pancreatic Cancer | Phase 1 Phase 2 | Not yet recruiting | November 30, 2025 | United States, Massachusetts ... More >> Dana Farber Cancer Institute Not yet recruiting Boston, Massachusetts, United States, 02215 Contact: Kimberly Perez, MD 617-632-6353 Kimberly_perez@dfci.harvard.edu Principal Investigator: Kimberly Perez, MD Less << |
NCT00421733 | Diabetic Nephropathy ... More >> Chronic Kidney Disease Less << | Phase 2 | Completed | - | - |
NCT01003275 | Chronic Kidney Disease | Phase 2 | Completed | - | United States, Washington ... More >> University of Washington Seattle, Washington, United States, 98195 Less << |
NCT00701805 | Secondary Hyperparathyroidism|... More >>Hemodialysis Less << | PHASE2 | COMPLETED | 2025-12-09 | Aichi, Japan|Chiba, Japan|Fuku... More >>oka, Japan|Hokkaido, Japan|Ibaragi, Japan|Kanagawa, Japan|Kumamoto, Japan|Nagano, Japan|Nagasaki, Japan|Osaka, Japan|Saitama, Japan|Tokyo, Japan Less << |
NCT01220050 | Renal Transplant ... More >> Secondary Hyperparathyroidism Less << | Phase 2 | Completed | - | Italy ... More >> Mario Negri Institute - Clinical Research Center for Rare Diseases Ranica, Bergamo, Italy, 24020 Less << |
NCT00701805 | Secondary Hyperparathyroidism|... More >>Hemodialysis Less << | PHASE2 | COMPLETED | 2025-12-09 | Aichi, Japan|Chiba, Japan|Fuku... More >>oka, Japan|Hokkaido, Japan|Ibaragi, Japan|Kanagawa, Japan|Kumamoto, Japan|Nagano, Japan|Nagasaki, Japan|Osaka, Japan|Saitama, Japan|Tokyo, Japan Less << |
NCT00537979 | Secondary Hyperparathyroidism ... More >> Dialysis Less << | Phase 4 | Completed | - | Mexico ... More >> Site Ref # / Investigator 19391 Jojutla Morelos, Mexico, CP 62900 Site Ref # / Investigator 19389 Mexico City, Mexico, CP 03900 Site Ref # / Investigator 19390 Mexico City, Mexico, CP 14000 Site Ref # / Investigator 19393 Mexico City, Mexico, CP 14080 Site Ref # / Investigator 19395 Mexico City, Mexico, CP 16070 Site Ref # / Investigator 19392 Mexico D.F., Mexico, CP 01030 Site Ref # / Investigator 19397 Mexico D.F., Mexico, CP 02080 Site Ref # / Investigator 19396 Mexico D.F., Mexico, CP 03650 Site Ref # / Investigator 19394 Mexico D.F., Mexico, CP 14140 Site Ref # / Investigator 19399 Puebla, Mexico, CP 72400 Site Ref # / Investigator 19398 Zapopan, Mexico, CP 45116 Site Ref # / Investigator 19388 Zapopan, Mexico, CP 45150 Less << |
NCT00428246 | Chronic Kidney Disease ... More >> Endothelial Dysfunction Inflammation Hypertension Less << | Not Applicable | Completed | - | United States, Indiana ... More >> Richard A. Rodebush VA Medical Center Indianapolis, Indiana, United States, 46202 Less << |
NCT01003275 | - | Completed | - | - | |
NCT01939977 | Secondary Hyperparathyroidism ... More >>Due to Renal Causes Less << | Phase 4 | Completed | - | Spain ... More >> Hospital Universitari Germans Trias I Pujol de Badalona Badalona, Barcelona, Spain, 08916 Hospital Universitari de Bellvitge L'Hospitalet de Llobregat, Barcelona, Spain, 08907 Hospital Universitario Marqués de Valdecilla Santander, Cantabria, Spain, 39008 Hospital Del Mar Barcelona, Spain, 08003 Fundació Puigvert-Iuna Barcelona, Spain, 08025 Hospital Universitari Vall D'Hebron Barcelona, Spain, 08035 Hospital Puerta Del Mar Cádiz, Spain, 11009 Hospital Reina Sofía Córdoba, Spain, 14004 Complexo Hospitalario Universitario A Coruna La Coruna, Spain, 15006 Complejo Hospitalario Universitario de Canarias Las Palmas De Gran Canaria, Spain, 38320 Hospital Ramón Y Cajal Madrid, Spain, 28034 Hospital Universitario 12 de Octubre Madrid, Spain, 28041 Complejo Hospitalario Regional de Málaga Málaga, Spain, 29010 Hospital Virgen Del Rocío Sevilla, Spain, 41013 Hospital Universitari I Politècnic La Fe Valencia, Spain, 46026 Hospital Universitario Miguel Servet Zaragoza, Spain, 50009 Less << |
NCT00537979 | - | Completed | - | - | |
NCT02090608 | Fabry Disease|Proteinuria | COMPLETED | 2025-12-13 | federico II university, depart... More >>ment of nephrology, Naples, 80129, Italy Less << | |
NCT02876211 | Anemia | Phase 4 | Recruiting | December 2019 | Spain ... More >> Son Espases University Hospital Recruiting Palma de Mallorca, Islas Baleares, Spain, 07120 Contact: Miguel Uriol, Ph.D.M.D. 00-34-871205000 ext 75212 miguelg.uriol@ssib.es Sub-Investigator: Sheila Cabello Pelegrin, MD Sub-Investigator: Juan Rey Valeriano, MD Sub-Investigator: Antonio Corral Paez, MD Sub-Investigator: Angel Garcia Alvarez, Pharmacist Sub-Investigator: Sonia Jimenez Mendoza, MD Sub-Investigator: Manuel Luque_Ramírez, Ph.D.MD. Principal Investigator: Miguel Uriol Rivera, Ph.D.MD. Less << |
NCT01020487 | Chronic Kidney Disease Stage 3... More >> and 4 Less << | Phase 3 | Completed | - | - |
NCT01939977 | - | Completed | - | - | |
NCT00616902 | Chronic Kidney Disease (CKD) S... More >>tage 5 Hypertrophy, Left Ventricular Less << | Phase 3 | Terminated(This study was prem... More >>aturely terminated due to low enrollment) Less << | - | - |
NCT00428246 | - | Completed | - | - | |
NCT02322632 | Healthy | Phase 1 | Completed | - | India ... More >> Lambda Therapeutic Research Ltd Ahmedabad, Gujarat, India, 3 80 061 Less << |
NCT01768351 | Anemia Chroni... More >>c Kidney Disease Less << | Phase 4 | Completed | - | Italy ... More >> Federico II University Naples, Italy, 80129 Less << |
NCT01382212 | End-Stage Renal Disease ... More >> Secondary Hyperparathyroidism Less << | Phase 3 | Completed | - | - |
NCT00616902 | - | Terminated(This study was prem... More >>aturely terminated due to low enrollment) Less << | - | - | |
NCT02372695 | Nephropathy | PHASE4 | TERMINATED | 2025-05-13 | - |
NCT01382212 | - | Completed | - | - | |
NCT03023748 | Endstage Renal Disease ... More >> Secondary Hyperparathyroidism Less << | Phase 4 | Active, not recruiting | January 2018 | Hong Kong ... More >> Queen Mary Hospital and Tung Wah Hospital Hong Kong, Hong Kong, 0000 Less << |
NCT01163162 | Chronic Kidney Disease | PHASE4 | COMPLETED | 2025-06-11 | Roudebush VA Medical Center, I... More >>ndianapolis, Indiana, 46202, United States Less << |
NCT02930902 | Pancreatic Cancer | Phase 1 | Recruiting | February 2020 | United States, Texas ... More >> The University of Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact gvaradha@mdanderson.org Less << |
NCT01020487 | - | Completed | - | - | |
NCT01163162 | Chronic Kidney Disease | PHASE4 | COMPLETED | 2025-06-11 | Roudebush VA Medical Center, I... More >>ndianapolis, Indiana, 46202, United States Less << |
NCT04064827 | Chronic Kidney Disease (CKD)|S... More >>econdary Hyperparathyroidism (SHPT) Less << | PHASE3 | RECRUITING | 2026-10-30 | Arkansas Children's Hospital /... More >>ID# 225417, Little Rock, Arkansas, 72202, United States|Stanford University /ID# 252150, Redwood City, California, 94063, United States|Children's National Medical Center /ID# 225991, Washington, District of Columbia, 20010-2916, United States|Holtz Childrens Hospital, University of Miami /ID# 225636, Miami, Florida, 33136-1005, United States|Nicklaus Children's Hospital /ID# 210517, Miami, Florida, 33155-3009, United States|Emory University /ID# 140665, Atlanta, Georgia, 30322-1014, United States|Boston Children's Hospital /ID# 162863, Boston, Massachusetts, 02115, United States|Duplicate_Levine Children's Specialty Center- Charlotte /ID# 216057, Charlotte, North Carolina, 28203-5866, United States|Children's Hospital of Philadelphia - Main /ID# 213802, Philadelphia, Pennsylvania, 19104-4319, United States|University of Texas Southwestern Medical Center /ID# 210495, Dallas, Texas, 75390-7208, United States|University of Utah /ID# 140669, Salt Lake City, Utah, 84112-5500, United States|Seattle Children's Hospital /ID# 162861, Seattle, Washington, 98105, United States|School of Medicine University of Puerto Rico-Medical Science Campus /ID# 140663, San Juan, 00935, Puerto Rico Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.40mL 0.48mL 0.24mL |
12.00mL 2.40mL 1.20mL |
24.00mL 4.80mL 2.40mL |