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Chemical Structure| 684234-56-8 Chemical Structure| 684234-56-8

Structure of PARP-1-IN-4
CAS No.: 684234-56-8

Chemical Structure| 684234-56-8

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PARP-1-IN-4 is an effective PARP-1 inhibitor with an IC50 of 302 μM, suitable for research on lung adenocarcinoma. This compound can inhibit the DNA damage repair pathway associated with PARP-1, showing anti-cancer potential.

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Product Details of PARP-1-IN-4

CAS No. :684234-56-8
Formula : C22H15Cl2N3O2
M.W : 424.28
SMILES Code : O=C(NC1=CC=C(Cl)C=C1)CN(N=C(C2=CC=C(Cl)C=C2)C3=C4C=CC=C3)C4=O
InChI Key :ZYDMHJZNLFTYOR-UHFFFAOYSA-N
Pubchem ID :1830002

Safety of PARP-1-IN-4

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of PARP-1-IN-4

epigenetics
DNA

Isoform Comparison

Biological Activity

Description
PARP-1 inhibitor PARP-1-IN-4 targets PARP-1, showing an IC50 value of 302 µM against it and is utilized in studies related to lung adenocarcinoma[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.36mL

0.47mL

0.24mL

11.78mL

2.36mL

1.18mL

23.57mL

4.71mL

2.36mL

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