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Chemical Structure| 1042780-52-8 Chemical Structure| 1042780-52-8

Structure of PARP10-IN-2
CAS No.: 1042780-52-8

Chemical Structure| 1042780-52-8

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PARP10-IN-2 is an effective mono-ADP-ribosyltransferase PARP10 inhibitor with an IC50 of 3.64 μM. This compound also inhibits PARP2 and PARP15, showing important potential applications in cancer treatment and DNA repair research.

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Product Details of PARP10-IN-2

CAS No. :1042780-52-8
Formula : C14H10N2O2
M.W : 238.24
SMILES Code : O=C(N)C1=CC=C(OC2=CC=C(C#N)C=C2)C=C1
MDL No. :N/A

Safety of PARP10-IN-2

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of PARP10-IN-2

epigenetics
DNA

Isoform Comparison

Biological Activity

Description
PARP10-IN-2 is a potent inhibitor of mono‐ADP‐ribosyltransferase PARP10, with an IC50 of 3.64 μM against human PARP10. It also exhibits strong inhibition of PARP2 and PARP15, with IC50 values of 27 μM and 11 μM for human PARP2 and PARP15, respectively[1].

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Bio Calculators
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1 mM

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4.20mL

0.84mL

0.42mL

20.99mL

4.20mL

2.10mL

41.97mL

8.39mL

4.20mL

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