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Chemical Structure| 593-39-5 Chemical Structure| 593-39-5

Structure of Petroselinic acid
CAS No.: 593-39-5

Chemical Structure| 593-39-5

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Synonyms: cis-Petroselinic Acid; PSA; 5-Heptadecylene-1-carboxylic Acid

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Product Details of Petroselinic acid

CAS No. :593-39-5
Formula : C18H34O2
M.W : 282.46
SMILES Code : CCCCCCCCCCC/C=C\CCCCC(O)=O
Synonyms :
cis-Petroselinic Acid; PSA; 5-Heptadecylene-1-carboxylic Acid
MDL No. :MFCD00046561

Safety of Petroselinic acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
Methicillin-sensitive Staphylococcus aureus (MSSA) 25923 20 mg/mL 24 hours Petroselinic acid significantly inhibited MSSA 25923 biofilm formation, with dramatic reductions in biofilm density and thickness. Microbiol Spectr. 2022 Jun 29;10(3):e0133022
Methicillin-resistant Staphylococcus aureus (MRSA) 33591 20 mg/mL 24 hours Petroselinic acid significantly inhibited MRSA 33591 biofilm formation, with dramatic reductions in biofilm density and thickness. Microbiol Spectr. 2022 Jun 29;10(3):e0133022
Methicillin-resistant Staphylococcus aureus (MRSA) MW2 20 mg/mL 24 hours Petroselinic acid significantly inhibited MRSA MW2 biofilm formation, with dramatic reductions in biofilm density and thickness. Microbiol Spectr. 2022 Jun 29;10(3):e0133022
BMDM cells 200 µM 6 hours Suppresses type I interferon production induced by cytosolic nucleic acids Biomolecules. 2025 Feb 24;15(3):329
BJ5ta cells 200 µM 6 hours Suppresses type I interferon production induced by cytosolic nucleic acids Biomolecules. 2025 Feb 24;15(3):329
U937 cells 200 µM 6 hours Suppresses type I interferon production induced by cytosolic nucleic acids Biomolecules. 2025 Feb 24;15(3):329
A549 cells 200 µM 6 hours Suppresses type I interferon production induced by cytosolic nucleic acids Biomolecules. 2025 Feb 24;15(3):329

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Porcine Porcine skin model Topical application 100 mg/mL 24 hours Petroselinic acid significantly inhibited S. aureus biofilm formation on porcine skin and almost completely prevented cell attachment. Microbiol Spectr. 2022 Jun 29;10(3):e0133022

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.54mL

0.71mL

0.35mL

17.70mL

3.54mL

1.77mL

35.40mL

7.08mL

3.54mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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