Structure of Pirtobrutinib
CAS No.: 2101700-15-4
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Pirtobrutinib is a highly selective and non-covalent BTK inhibitor, which may be regarded as a third generation BTK inhibitor. It potently inhibited the cellular activity (measured by Y223 autophosphorylation) of BTK C481S, T and R mutations and displayed strong equilibrium binding to WT BTK and several BTK C481 substitution mutations. It may overcome acquired resistance to covalent BTK inhibitors in patients without significant off-target toxicity.
Synonyms: LOXO-305; LY 3527727; RXC-005
4.5
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Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
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CAS No. : | 2101700-15-4 |
Formula : | C22H21F4N5O3 |
M.W : | 479.43 |
SMILES Code : | C(N)(=O)C=1C(=NN([C@H](C(F)(F)F)C)C1N)C2=CC=C(CNC(=O)C3=C(OC)C=CC(F)=C3)C=C2 |
Synonyms : |
LOXO-305; LY 3527727; RXC-005
|
MDL No. : | N/A |
InChI Key : | FWZAWAUZXYCBKZ-NSHDSACASA-N |
Pubchem ID : | 129269915 |
GHS Pictogram: |
![]() |
Signal Word: | Warning |
Hazard Statements: | H302-H315-H319-H335 |
Precautionary Statements: | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT06390956 | Marginal Zone Lymphoma | PHASE2 | RECRUITING | 1932-12-01 | Huntsman Cancer Institute at U... More >>niversity of Utah, Salt Lake City, Utah, 84112, United States Less << |
NCT05172700 | Leukemia, Lymphocytic, Chronic... More >>, B-Cell|Lymphoma, Lymphocytic, Small|Lymphoma, Mantle-Cell|Waldenstrom Macroglobulinemia|Ritcher's Transformation, Syndrome Less << | APPROVED_FOR_MARKETING | - | - | |
NCT06190678 | Healthy|Renal Insufficiency | PHASE1 | COMPLETED | 2021-06-04 | Orange County Research Institu... More >>te, Anaheim, California, 92801, United States|Riverside Clinical Research, Edgewater, Florida, 32132, United States|Clinical Pharmacology of Miami, Miami, Florida, 33014, United States|Orlando Clinical Research Center, Orlando, Florida, 32809, United States|Prism Research, Saint Paul, Minnesota, 55114, United States Less << |
NCT06190691 | Healthy|Hepatic Insufficiency | PHASE1 | COMPLETED | 2021-12-30 | Orange County Research Institu... More >>te, Anaheim, California, 92801, United States|Orange County Research Center, Tustin, California, 92780, United States|Riverside Clinical Research, Edgewater, Florida, 32132, United States|Clinical Pharmacology of Miami, Miami, Florida, 33014, United States|Advanced Pharma Clinical Research, Miami, Florida, 33147, United States|Orlando Clinical Research Center, Orlando, Florida, 32809, United States|The Texas Liver Institute, San Antonio, Texas, 78215, United States|Pinnacle Clinical Research, San Antonio, Texas, 78229, United States Less << |
NCT06588478 | Chronic Lymphocytic Leukemia|S... More >>mall Lymphocytic Lymphoma Less << | PHASE2 | RECRUITING | 2025-12-28 | Ironwood Cancer & Research Cen... More >>ters, Chandler, Arizona, 85224, United States|City of Hope National Medical Center, Duarte, California, 91010, United States|City of Hope National Medical Center, Irvine, California, 92618, United States|Palo Alto Medical Foundation Research Institute (PAMFRI), Palo Alto, California, 94304, United States|Stanford Cancer Center, Palo Alto, California, 94304, United States|Rocky Mountain Cancer Center, Aurora, Colorado, 80012, United States|University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami, Florida, 33136, United States|Mission Cancer + Blood, Des Moines, Iowa, 50309, United States|Saint Elizabeth Medical Center Edgewood, Edgewood, Kentucky, 41017, United States|American Oncology Partners of Maryland, PA, Bethesda, Maryland, 20817, United States|Boston Medical Center, Boston, Massachusetts, 02118, United States|Gulfport Memorial Hospital, Gulfport, Mississippi, 39501, United States|Clinical Research Alliance, Westbury, New York, 11590, United States|East Carolina University, Greenville, North Carolina, 27834, United States|Williamette Valley Cancer Institute & Research Center, Eugene, Oregon, 97401, United States|Cancer Care Associates Of York, York, Pennsylvania, 17403, United States|The West Clinic, PLLC dba West Cancer Center, Germantown, Tennessee, 38138, United States|Sarah Cannon Research Institute/SCRI, Nashville, Tennessee, 37203, United States|USO-Texas Oncology-Central/South Texas, Austin, Texas, 78705, United States|USO-Virginia Oncology Associates, Hampton, Virginia, 23666, United States|USO-Northwest Cancer Specialists, PC, Vancouver, Washington, 98683, United States|Medical College of Wisconsin, Milwaukee, Wisconsin, 53226, United States|Bankstown-Lidcombe Hospital, Bankstown, New South Wales, 2200, Australia|Coffs Harbour Health Campus, Coffs Harbour, New South Wales, 2450, Australia|Calvary Mater Newcastle, Waratah, New South Wales, 2298, Australia|Princess Alexandra Hospital, Woolloongabba, Queensland, 4102, Australia|ICON Cancer Centre - Kurralta Park, Kurralta Park, South Australia, 5037, Australia|Royal Hobart Hospital, Hobart, Tasmania, 7000, Australia|Box Hill Hospital, Box Hill, Victoria, 3128, Australia|Latrobe Regional Health, Traralgon, Victoria, 3844, Australia|The Perth Blood Institute - West Perth, West Perth, Western Australia, 6005, Australia|Clinique Saint Pierre, Ottignies, Brabant Wallon, 1340, Belgium|Institut Jules Bordet, Anderlecht, Bruxelles-Capitale, Région De, 1070, Belgium|Groupe Jolimont, La Louvière, Hainaut, 7100, Belgium|CHR Verviers - La Tourelle, Verviers, Liège, 4800, Belgium|UZ Gent, Gent, Oost-Vlaanderen, 9000, Belgium|AZ Nikolaas, Sint-Niklaas, Oost-Vlaanderen, B-9100, Belgium|UZ Leuven, Leuven, Vlaams-Brabant, 3000, Belgium|AZ Sint-Jan Brugge-Oostende AV, Brugge, West-Vlaanderen, 8000, Belgium|AZ Delta vzw, Roeselare, West-Vlaanderen, 8800, Belgium|Royal Victoria Regional Health Centre, Barrie, Ontario, L4M 6M2, Canada|CIUSSS- saguenay-Lac-Saint-Jean, Chicoutimi, Quebec, G7H 5H6, Canada|Saskatoon Cancer Centre, Saskatoon, Saskatchewan, S7N4H4, Canada|Fakultní nemocnice Brno Bohunice, Brno, Brno-město, 625 00, Czechia|Fakultni nemocnice Hradec Kralove, Hradec Kralove, Hradec Králové, 500 05, Czechia|Fakultni nemocnice Kralovske Vinohrady, PRague, Praha 10, 100 34, Czechia|Vseobecna fakultni nemocnice v Praze, Praha 2, 12808, Czechia|Aarhus Universitetshospital, Skejby, Aarhus, Midtjylland, 8200, Denmark|Roskilde Sygehus, Roskilde, Sj?lland, 4000, Denmark|Odense Universitetshospital, Odense, Syddanmark, 5000, Denmark|Centre Antoine-Lacassagne, Nice, Alpes-Maritimes, 06189, France|Groupe Hospitalier de la Région de Mulhouse et Sud Alsace - H?pital Emile Muller, Mulhouse, Alsace, 68100, France|Centre Hospitalier Universitaire de Caen - H?pital C?te de Nacre, Caen, Calvados, 14033, France|Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE, Toulouse, Haute-Garonne, 31059, France|Centre Hospitalier Régional Universitaire de Tours - H?pital Bretonneau, Tours, Indre-et-Loire, 37044 Cedex 9, France|Centre Hospitalier du Mans, Le Mans, Sarthe, 72000, France|Centre Hospitalier d'Argenteuil Victor Dupouy, Argenteuil, Val-d'Oise, 95107, France|Klinikum Aschaffenburg-Alzenau, Aschaffenburg, Bayern, 63739, Germany|Centrum für H?matologie und Onkologie Bethanien, Frankfurt, Hessen, 60389, Germany|OSP G?ttingen, Goettingen, Niedersachsen, 37073, Germany|Onkologisches Ambulanzzentrum Hannover, Hannover, Niedersachsen, 30171, Germany|Gemeinschaftspraxis für H?matologie und Onkologie Münster, Münster, Nordrhein-Westfalen, 48153, Germany|InVO Institut für Versorgungsforschung in der Onkologie, Koblenz, Rheinland-Pfalz, 56068, Germany|Evangelismos General Hospital of Athens, Athens, Attikí, 106 76, Greece|Attikon General University Hospital, Chaidari, Attikí, 12462, Greece|General Hospital of Athens "Laiko", Αthens, Attikí, 11527, Greece|G. Papanikolaou General Hospital, Thessaloniki, Thessaloníki, 570 10, Greece|Pécsi Tudományegyetem Klinikai K?zpont, Pécs, Baranya, 7624, Hungary|Szegedi Tudományegyetem Szent-Gy?rgyi Albert Klinikai K?zpont, Szeged, Csongrád, 6725, Hungary|Semmelweis University, Budapest, 1088, Hungary|Dél-Pesti Centrumkórház, Budapest, 1097, Hungary|Azienda Ospedaliero Universitaria S.Anna, Cona, Emilia-Romagna, 44124, Italy|Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore, Roma, Lazio, 00168, Italy|ASST Grande Ospedale Metropolitano Niguarda, Milan, Lombardia, 20162, Italy|A.O.U.C. Policlinico di Bari, Bari, Puglia, 70124, Italy|Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO, Palermo, Sicilia, 90146, Italy|Azienda Ospedaliera Universitaria Careggi, Firenze, Toscana, 50134, Italy|AO Santa Maria della Misericordia, Perugia, Umbria, 06132, Italy|Azienda Ospedale - Università Padova, Padova, Veneto, 35128, Italy|Azienda Ospedaliero Universitaria Maggiore della Carità, Novara, 28100, Italy|AOU Policlinico Umberto I, Roma, 00161, Italy|Chonnam National University Hwasun Hospital, Hwasun-gun, Jeonranamdo, 58128, Korea, Republic of|Seoul National University Hospital, Seoul, Seoul-teukbyeolsi [Seoul], 03080, Korea, Republic of|Severance Hospital, Yonsei University Health System, Seoul, Seoul-teukbyeolsi [Seoul], 03722, Korea, Republic of|Samsung Medical Center, Seoul, Seoul-teukbyeolsi [Seoul], 06351, Korea, Republic of|The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul], 06591, Korea, Republic of|The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul], 07345, Korea, Republic of|Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroc?awiu, Wroc?aw, Dolno?l?skie, 50-367, Poland|Szpital Uniwersytecki Nr 2 im. dr J. Biziela w Bydgoszczy, Bydgoszcz, Kujawsko-pomorskie, 85-168, Poland|Pratia MCM Krakow, Kraków, Ma?opolskie, 30-727, Poland|AIDPORT Sp. z o.o., Skórzewo, Wielkopolskie, 60-185, Poland|Pratia Onkologia Katowice, Katowice, ?l?skie, 40-519, Poland|Fundeni Clinical Institute, Bucuresti, Bucure?ti, 022328, Romania|Ovidius Clinical Hospital OCH, Ovidiu, Constan?a, 905900, Romania|Spitalul Clinic Municipal Filantropia Craiova, Craiova, Dolj, 200143, Romania|Spitalul Clinic Col?ea, Bucure?ti, 030171, Romania|Institutul Oncologic Cluj, Cluj, 400015, Romania|Institutul Regional de Oncologie, Ia?i, 700483, Romania|Fakultna nemocnica s poliklinikou F.D.Roosevelta Banska Bystrica, Banska Bystrica, Banskobystricky Kraj, 975 17, Slovakia|Narodny onkologicky ustav, Bratislava, Bratislavsky Kraj, 833 10, Slovakia|Univerzitna Nemocnica L. Pasteura Kosice, Kosice, Ko?icky Kraj, 040 11, Slovakia|Univerzitna nemocnica Martin, Martin, ?ilinsky Kraj, 036 59, Slovakia|Hospital Universitario Virgen Macarena, Sevilla, Andalucía, 41009, Spain|Hospital Universitario Central de Asturias, Oviedo, Asturias, 33011, Spain|Institut Català d'Oncologia (ICO) - Badalona, Badalona, Barcelona [Barcelona], 08916, Spain|Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona], 08035, Spain|Institut Català d'Oncologia - L'Hospitalet, L'Hospitalet Del Llobregat, Barcelona [Barcelona], 08908, Spain|Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, 39008, Spain|Hospital Clínic de Barcelona, Barcelona, Catalunya [Catalu?a], 08036, Spain|Clinica Universidad de Navarra, Madrid, Madrid, Comunidad De, 28027, Spain|Hospital Universitario Infanta Leonor, Madrid, Madrid, Comunidad De, 28031, Spain|MD Anderson Cancer Center, Madrid, Madrid, Comunidad De, 28033, Spain|Hospital Universitario Ramón y Cajal, Madrid, Madrid, Comunidad De, 28034, Spain|Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid, Comunidad De, 28222, Spain|Hospital Costa del Sol, Marbella, Málaga, 29603, Spain|Hospital Universitario 12 de Octubre, Madrid, 28041, Spain|Hospital Universitario Quironsalud Madrid, Madrid, 28223, Spain|Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca, Salamanca, 37007, Spain|Hospital Universitario Virgen Del Rocio, Sevilla, 41013, Spain|Kocaeli üniversitesi, Izmit, Kocaeli, 41380, Turkey|Sakarya University School of Medicine, Adapazar?, Sakarya, 54100, Turkey|Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arast?rma Hastanesi, Ankara, 06200, Turkey|Ankara University Health Practice and Research Hospitals, Ankara, 06620, Turkey|Memorial Antalya Hospital, Antalya, 07090, Turkey|Yeditepe üniversitesi Ko?uyolu Hastanesi, Istanbul, 34718, Turkey|Ege Universitesi Hastanesi, Izmir, 35100, Turkey|VM Medical Park Mersin Hastanesi, Mersin, 33200, Turkey|Ondokuz May?s Universitesi, Samsun, 55139, Turkey|Maidstone Hospital, Maidstone, Kent, ME16 9QQ, United Kingdom|Lincoln County Hospital, Lincoln, Lincolnshire, LN2 5QY, United Kingdom|Northwick Park Hospital, Harrow, London, City Of, HA1 3UJ, United Kingdom|Hammersmith Hospital, London, London, City Of, W12 0HS, United Kingdom|Heartlands Hospital, Birmingham, B9 5SS, United Kingdom|The Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN, United Kingdom|St James's University Hospital, Leeds, LS9 7TF, United Kingdom|Clatterbridge Cancer Centre - Liverpool, Liverpool, L7 8YA, United Kingdom|Singleton Hospital, Swansea, SA2 8QA, United Kingdom Less << |
NCT06181006 | Healthy | PHASE1 | COMPLETED | 2020-12-01 | Covance Clinical Research Unit... More >>, Daytona Beach, Florida, 32117, United States Less << |
NCT06812715 | Chronic Lymphocytic Leukemia | PHASE2 | NOT_YET_RECRUITING | 2025-05-31 | Peter MacCallum Cancer Centre,... More >> Melbourne, Victoria, 3000, Australia|Alfred Hospital, Melbourne, Victoria, 3004, Australia|Monash Medical Centre, Melbourne, Victoria, 3168, Australia Less << |
NCT06180980 | Healthy | PHASE1 | COMPLETED | 2021-03-08 | Covance Clinical Research Unit... More >>, Daytona Beach, Florida, 32117, United States Less << |
NCT06258174 | Healthy | PHASE1 | COMPLETED | 2021-12-22 | Labcorp Drug Development, Dall... More >>as, Texas, 75247, United States Less << |
NCT04849416 | Leukemia, Lymphoid|Lymphoma, N... More >>on-Hodgkin|Lymphoma, Mantle-Cell|Lymphoma, Large B-Cell, Diffuse|Lymphoma, B-Cell|Lymphoma, B-Cell, Marginal Zone|Leukemia, Lymphocytic, Chronic, B-Cell Less << | PHASE2 | ACTIVE_NOT_RECRUITING | 2025-04-25 | Wannan Medical College Yijisha... More >>n Hospital, Wuhu, Anhui, 241001, China|Beijing Cancer hospital, Beijing, Beijing, 100142, China|Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, 510515, China|Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 511400, China|Hainan General Hospital, Haikou, Hainan, 570311, China|Affiliated Hospital of Hebei University, Baoding, Hebei, 71066, China|Xingtai People's Hospital, Xingtai, Hebei, 054031, China|Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, 150081, China|The First Affiliated Hospital of Henan University of Science &Technology, Luoyang Shi, Henan, 471003, China|Henan Cancer Hospital, Zhengzhou, Henan, 450008, China|Xiangya Hospital Central South University, Changsha, Hunan, 410008, China|Hunan Cancer Hospital, Changsha, Hunan, 410013, China|Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, 210000, China|The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215066, China|The First Hospital of Jilin University, Changchun, Jilin, 130021, China|Xi'an International Medical Center Hospital, Xi'an, Shaanxi, 710126, China|Sichuan Cancer Hospital, Chengdu, Sichuan, 610041, China|Institute of hematology&blood disease hospital, Tianjin, Tianjin, 300020, China|Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, 300060, China|Xinjiang Medical University Cancer Hospital - Urumqi, Urumqi, Xinjiang, 830000, China|Zhejiang Cancer Hospital, Hangzhou, Zhejiang, 310022, China|Shanghai East Hospital, Shanghai, 200120, China Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.09mL 0.42mL 0.21mL |
10.43mL 2.09mL 1.04mL |
20.86mL 4.17mL 2.09mL |
Tags: Pirtobrutinib | LOXO-305 | Amides | Fluorinated Building Blocks | BTK | Organic Building Blocks | Protein Tyrosine Kinase/RTK | Angiogenesis | 2101700-15-4
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P101 | If medical advice is needed,have product container or label at hand. |
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P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
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P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
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P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
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P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
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P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
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P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
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P332 | IF SKIN irritation occurs: |
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P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
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P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
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