Home Cart Sign in  
Chemical Structure| 514814-49-4 Chemical Structure| 514814-49-4

Structure of PMX 205
CAS No.: 514814-49-4

Chemical Structure| 514814-49-4

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

PMX 205 is an antagonist of C5a receptor peptide with IC50 of 31 nM.

Synonyms: PMX 205

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of PMX 205

CAS No. :514814-49-4
Formula : C45H62N10O6
M.W : 839.04
SMILES Code : [H][C@@]1(C(N[C@H](CC2CCCCC2)C(N3)=O)=O)CCCN1C([C@@H](NC(CCC4=CC=CC=C4)=O)CCCNC([C@H](CCCNC(N)=N)NC([C@@H]3CC5=CNC6=CC=CC=C56)=O)=O)=O
Synonyms :
PMX 205
MDL No. :MFCD31657373

Safety of PMX 205

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335-H412
Precautionary Statements:P261-P264-P271-P273-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501

Isoform Comparison

Biological Activity

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
BALB/c mice Snake envenomation model Subcutaneous injection 1 or 2 mg/kg body weight 24 hours and 1 hour before induction To assess the role of the C5a-C5aR1 axis in N. annulifera venom-induced local and systemic reactions. Results showed that PMX205 significantly reduced edema and systemic inflammatory responses and prevented the development of acute lung injury. PMC8082402

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.19mL

0.24mL

0.12mL

5.96mL

1.19mL

0.60mL

11.92mL

2.38mL

1.19mL

 

Historical Records

Categories