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Chemical Structure| 2089415-51-8 Chemical Structure| 2089415-51-8

Structure of PQM130
CAS No.: 2089415-51-8

Chemical Structure| 2089415-51-8

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PQM130 is a brain-penetrating hybrid compound of Weirolin and donepezil, serving as a multi-target candidate molecule for studying Aβ1-42 oligomer-induced neurotoxicity and exhibiting anti-inflammatory activity. PQM130 is a potential neuroprotective anti-Alzheimer's disease (AD) active molecule.

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Product Details of PQM130

CAS No. :2089415-51-8
Formula : C23H27NO4
M.W : 381.46
SMILES Code : O=C(/C=C/C1=CC(OC)=C(O)C=C1)OCC(CC2)CCN2CC3=CC=CC=C3
InChI Key :QJDRBHVMOOPIGE-CSKARUKUSA-N
Pubchem ID :137643434

Safety of PQM130

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
PQM130, a Feruloyl-Donepezil brain injury hybrid, is a multi-target drug candidate that fights neurotoxicity caused by Aβ1-42 oligomers (AβO) and has anti-inflammatory activity. PQM130 is a neuroprotective compound developed as an anti-AD drug[1].

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Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.62mL

0.52mL

0.26mL

13.11mL

2.62mL

1.31mL

26.22mL

5.24mL

2.62mL

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