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Chemical Structure| 104632-26-0 Chemical Structure| 104632-26-0
Chemical Structure| 104632-26-0

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Pramipexole is an agonist of dopamine receptors D2, D3, and D4 (Ki = 3.9, 2.2, 0.5, and 5.1 nM respectively) and it is indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS).

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Product Details of Pramipexole

CAS No. :104632-26-0
Formula : C10H17N3S
M.W : 211.33
SMILES Code : CCCN[C@H]1CCC2=C(C1)SC(N)=N2
MDL No. :MFCD00869076
InChI Key :FASDKYOPVNHBLU-ZETCQYMHSA-N
Pubchem ID :119570

Safety of Pramipexole

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of Pramipexole

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 104632-26-0 ]

[ 104632-26-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 1046124-81-5 ]
  • [ 68-11-1 ]
  • [ 6375-65-1 ]
  • [ 104632-26-0 ]
  • 2
  • [ 104632-26-0 ]
  • [ 130-85-8 ]
  • pramipexole pamoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
99% In dimethyl sulfoxide; ethyl acetate; at 20℃; Pramipexole (5.0 g, 23.44 mmol) and <strong>[130-85-8]Pamoic acid</strong> (9.08 g, 23.44 mmol) was dissolved by stirring at room temperature in DMSO (50 mL). The solution was then slowly added to ethyl acetate (2L) at room temperature to generate a white solid. The solid was collected on a filter and dried in vacuum at 45 °C to give pramipexole pamoate at a 1: 1 Molar ratio of Pramipexole to <strong>[130-85-8]Pamoic acid</strong> (14.0g, 99.0percent).
 

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