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Structure of 17431-03-7

Chemical Structure| 17431-03-7

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Product Details of [ 17431-03-7 ]

CAS No. :17431-03-7
Formula : C7H15NO2
M.W : 145.20
SMILES Code : CC(C)[C@H](N)C(OCC)=O
MDL No. :MFCD12796096

Safety of [ 17431-03-7 ]

Application In Synthesis of [ 17431-03-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17431-03-7 ]

[ 17431-03-7 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 17431-03-7 ]
  • [ 2491-15-8 ]
  • N-Formyl-glycyl-L-valin-ethylester [ No CAS ]
  • 2
  • [ 17431-03-7 ]
  • [ 2338-54-7 ]
  • (S)-ethyl 2-(4-methoxy-2-methylphenylamino)-3-methylbutanoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
83% With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; In 1,2-dichloro-ethane; at 25℃; for 48h;Irradiation; Inert atmosphere; 1-Fluoro-4-methoxy-2-methylbenzene a11 (0.0140 g, 0.10 mmol), acridine photosensitizer (A) (0.0029 g, 0.005 mmol) and L-guanidine were added sequentially under argon atmosphere. Ethyl acetate b1 (0.0218 g, 0.15 mmol), 1,2-dichloroethane (DCE) 2.0 mL.The reaction was irradiated for 48 hours under a 6W blue light at room temperature.After completion of the reaction, the solvent was evaporated under reduced pressure and purified by column chromatography, eluting solvent: (V) petroleum ether / (V) ethyl acetate = 20/1.A yellow liquid (28) (0.0140 g, 83%) was obtained.
  • 3
  • [ 17431-03-7 ]
  • [ 103291-07-2 ]
  • C14H20BrNO3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
94% With 3,6?di?tert?butyl?9?mesityl?10?phenylacridin?10?ium tetrafluoroborate; In 1,2-dichloro-ethane; for 72h;Irradiation; Inert atmosphere; 4-Bromo-1-fluoro-2-methoxybenzene a15 (0.0204 g, 0.10 mmol), acridine photosensitizer (A) (0.0029 g, 0.005 mmol) and L-valine were added sequentially under argon atmosphere. Ethyl b1 (0.0218 g, 0.15 mmol), 1,2-dichloroethane (DCE) 2.0 mL.The reaction was irradiated under a 6W blue light lamp at 50 C for 72 h.After completion of the reaction, the solvent was evaporated under reduced pressure and purified by column chromatography, eluting solvent: (V) petroleum ether / (V) ethyl acetate = 30/1.Yellow liquid (32) (0.0109 g, 94%) was obtained.
  • 4
  • [ 17431-03-7 ]
  • [ 42017-89-0 ]
  • [ 98-11-3 ]
  • (2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoyloxy)ethyl-2-amino-3-methylbutanoate monobenzenesulfonate [ No CAS ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; A solution of 4-chloromethyl-5-1,3-dioxolen-2-one(2.94 g, 20 mmol) was added to <strong>[42017-89-0]fenofibric acid</strong>(3.18 g, 10 mmol) and K2CO3 (2.76 g, 20 mmol) inN,N-dimethylacetamide (64 mL) at room temperatureat such a rate that the reaction maintained an internaltemperature of 60-65 C overnight. The reaction mixturewas cooled to 0 C and water (100 mL) was added slowly.The resulting mixture was stirred at room temperature for1.5 h, extracted with ethyl acetate (100 mL), and washedwith brine (150 mL × 3). The solvent was distilled offunder reduced pressure to obtain a residue. The residue waspurified further by column chromatography to give the titlecompounds. The following compounds were synthesizedaccording to this procedure.
  • 5
  • [ 17431-03-7 ]
  • [ 42017-89-0 ]
  • [ 104-15-4 ]
  • 2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoyloxy)ethyl-2-amino-3-methylbutanoate monotosylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; A solution of 4-chloromethyl-5-1,3-dioxolen-2-one(2.94 g, 20 mmol) was added to <strong>[42017-89-0]fenofibric acid</strong>(3.18 g, 10 mmol) and K2CO3 (2.76 g, 20 mmol) inN,N-dimethylacetamide (64 mL) at room temperatureat such a rate that the reaction maintained an internaltemperature of 60-65 C overnight. The reaction mixturewas cooled to 0 C and water (100 mL) was added slowly.The resulting mixture was stirred at room temperature for1.5 h, extracted with ethyl acetate (100 mL), and washedwith brine (150 mL × 3). The solvent was distilled offunder reduced pressure to obtain a residue. The residue waspurified further by column chromatography to give the titlecompounds. The following compounds were synthesizedaccording to this procedure.
 

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