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Chemical Structure| 5293-84-5 Chemical Structure| 5293-84-5

Structure of 5293-84-5

Chemical Structure| 5293-84-5

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Product Details of [ 5293-84-5 ]

CAS No. :5293-84-5
Formula : C19H17Cl2P
M.W : 347.22
SMILES Code : ClC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Cl-]
MDL No. :MFCD00011867
InChI Key :SXYFAZGVNNYGJQ-UHFFFAOYSA-M
Pubchem ID :197823

Safety of [ 5293-84-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 5293-84-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5293-84-5 ]

[ 5293-84-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 33985-71-6 ]
  • [ 5293-84-5 ]
  • (1Z)-1-chloro-2-(9'-julolidinyl)-ethylene [ No CAS ]
  • [ 1285688-63-2 ]
YieldReaction ConditionsOperation in experiment
To a solution of chloromethyltriphenylphosphonium chloride (3.98 mmol, 1.6 equiv) in THF (90 mL) at 0 C under an argon atmosphere, was slowly added n-BuLi (1.5 M in hexane, 3.74 mmol, 1.5 equiv). After 30 min stirring at -78 C, 9-formyljulolidine (2.49 mmol, 1.0 equiv) in THF (20 mL) was slowly added. The reaction mixture was stirred for 10 min at -78 C and then for 14 h at room temperature. The reaction mixture was quenched with a 10% aqueous solution of NaHCO3 (20 mL). The resulting solution was then extracted with dichloromethane (3×15 mL). The combined organic extracts were washed with saturated brine (10 mL) and dried over MgSO4. After evaporation the crude product was further purified by silica gel column chromatography (pentane/ether: 15/1) to give a mixture of two isomers 4a/4b (65/35). Yield: 0.574 g (99%) as a yellow oil. IR: 3073, 3005, 2937, 2885, 1604, 1505, 1464, 1282, 1073, 1053, 974, 737, 685, 620 cm-1. MS (EI) m/z: 233-235 (M+, 100%, 34%), 204 (17%), 196 (25%), 168 (24%), 154 (14%), 141 (11%), 115 (13%), 77 (4%). Anal. Calcd for C14H16ClN (233.45): C 71.96, H 6.85, N 6.00; found: C 71.81, H 6.91, N 5.98.
 

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